Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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353500 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Bone morphogenetic protein 8a |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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BMP8A |
SynonymsGene synonyms aliases
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OP-2, Op2 |
ChromosomeChromosome number
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1 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1p34.3 |
SummarySummary of gene provided in NCBI Entrez Gene.
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This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
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UniProt ID |
Q7Z5Y6 |
Protein name |
Bone morphogenetic protein 8A (BMP-8A) |
Protein function |
Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (By similarity). Signaling protein involved in regulation o |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00688 |
TGFb_propeptide |
29 → 251 |
TGF-beta propeptide |
Family |
PF00019 |
TGF_beta |
300 → 401 |
Transforming growth factor beta like domain |
Domain |
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Sequence |
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Sequence length |
402 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Vascular diseases |
Peripheral Arterial Diseases |
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27082954 |
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