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SEPTIN14 (septin 14)
Gene
Gene Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
346288
Gene nameGene Name - the full gene name approved by the HGNC.
Septin 14
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
SEPTIN14
SynonymsGene synonyms aliases
SEPT14, Septin-14
ChromosomeChromosome number
7
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
7p11.2
SummarySummary of gene provided in NCBI Entrez Gene.
SEPT14 is a member of the highly conserved septin family of GTP-binding cytoskeletal proteins implicated in membrane transport, apoptosis, cell polarity, cell cycle regulation, cytokinesis, and other cellular functions (Peterson et al., 2007 [PubMed 17922
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0003924 Function GTPase activity IBA 21873635
GO:0005515 Function Protein binding IPI 17922164, 32296183
GO:0005525 Function GTP binding IEA
GO:0005940 Component Septin ring IBA 21873635
GO:0015630 Component Microtubule cytoskeleton IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Associated diseases
MIM
HGNC
e!Ensembl
Protein
Gene Gene ontology Other IDs Protein Associated diseases
UniProt ID Q6ZU15
Protein name Septin-14
Protein function Filament-forming cytoskeletal GTPase (Probable). Involved in the migration of cortical neurons and the formation of neuron leading processes during embryonic development (By similarity). Plays a role in sperm head formation during spermiogenesis
PDB 8SJJ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00735 Septin
49 → 321
Septin
 Domain
Sequence
Sequence length 432
Interactions View interactions
Associated diseases
Gene Gene ontology Other IDs Protein Associated diseases
Causal
Disease name Disease term dbSNP ID References
Glioblastoma Glioblastoma, Glioblastoma Multiforme rs121913500, rs886042842, rs1555138291, rs1558518449, rs1567176006, rs1558650888 23917401
Unknown
Disease name Disease term dbSNP ID References
Giant cell glioblastoma Giant Cell Glioblastoma 24071942, 23917401, 24075187
Gliosarcoma gliosarcoma 24071942, 24075187

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