Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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3187 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Heterogeneous nuclear ribonucleoprotein H1 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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HNRNPH1 |
SynonymsGene synonyms aliases
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HNRPH, HNRPH1, NEDCDS, hnRNPH |
ChromosomeChromosome number
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5 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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5q35.3 |
SummarySummary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nuc |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
|
UniProt ID |
P31943 |
Protein name |
Heterogeneous nuclear ribonucleoprotein H (hnRNP H) [Cleaved into: Heterogeneous nuclear ribonucleoprotein H, N-terminally processed] |
Protein function |
This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates p |
PDB |
2LXU
,
6DHS
,
7ZUG
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00076 |
RRM_1 |
13 → 84 |
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
Domain |
PF00076 |
RRM_1 |
113 → 182 |
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
Domain |
PF08080 |
zf-RNPHF |
255 → 290 |
RNPHF zinc finger |
Domain |
PF00076 |
RRM_1 |
291 → 358 |
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
Domain |
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Sequence |
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Sequence length |
449 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Lymphoblastic leukemia |
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-cell acute lymphoblastic leukemia |
rs387906351, rs104894562, rs398122513, rs398122840, rs398123063, rs1057524466, rs1064796115, rs1064795660, rs1064793129, rs1064796227, rs1567887558, rs1161194345, rs1597558200, rs1406320425, rs1597566470, rs1597566699, rs1597567692, rs1597567985, rs1438890364, rs1288977950, rs1597552140, rs1597566356, rs1597566726, rs1597568117, rs2069719445, rs2069729948, rs2070018439, rs745708044, rs1169577591 |
23673860 |
Prostate cancer |
Malignant neoplasm of prostate |
rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 |
17566973 |
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Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Prostatic neoplasms |
Prostatic Neoplasms |
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17566973 |
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