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ANXA7 (annexin A7)

Gene

310

Annexin A7

ANXA7

ANX7, SNX, SYNEXIN

10q22.2

Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and

Show/Hide all(210)

miRTarBase ID	miRNA	Experiments	Reference
MIRT023283	hsa-miR-122-5p	Proteomics	21750653
MIRT048217	hsa-miR-196a-5p	CLASH	23622248
MIRT043161	hsa-miR-324-5p	CLASH	23622248
MIRT439134	hsa-miR-10b-5p	3'LIFE	25074381
MIRT439134	hsa-miR-10b-5p	3'LIFE	25074381
MIRT786608	hsa-miR-10a	CLIP-seq
MIRT786609	hsa-miR-10b	CLIP-seq
MIRT786610	hsa-miR-124	CLIP-seq
MIRT786611	hsa-miR-1252	CLIP-seq
MIRT786612	hsa-miR-137	CLIP-seq
MIRT786613	hsa-miR-19a	CLIP-seq
MIRT786614	hsa-miR-19b	CLIP-seq
MIRT786615	hsa-miR-3145-3p	CLIP-seq
MIRT786616	hsa-miR-3194-3p	CLIP-seq
MIRT786617	hsa-miR-323-3p	CLIP-seq
MIRT786618	hsa-miR-3665	CLIP-seq
MIRT786619	hsa-miR-3714	CLIP-seq
MIRT786620	hsa-miR-3910	CLIP-seq
MIRT786621	hsa-miR-4317	CLIP-seq
MIRT786622	hsa-miR-506	CLIP-seq
MIRT786623	hsa-miR-548n	CLIP-seq
MIRT786624	hsa-miR-570	CLIP-seq
MIRT786625	hsa-miR-616	CLIP-seq
MIRT786626	hsa-miR-657	CLIP-seq
MIRT786619	hsa-miR-3714	CLIP-seq
MIRT786627	hsa-miR-4328	CLIP-seq
MIRT786628	hsa-miR-4672	CLIP-seq
MIRT786629	hsa-miR-603	CLIP-seq
MIRT786612	hsa-miR-137	CLIP-seq
MIRT786615	hsa-miR-3145-3p	CLIP-seq
MIRT786608	hsa-miR-10a	CLIP-seq
MIRT786609	hsa-miR-10b	CLIP-seq
MIRT786613	hsa-miR-19a	CLIP-seq
MIRT786614	hsa-miR-19b	CLIP-seq
MIRT786617	hsa-miR-323-3p	CLIP-seq
MIRT2172439	hsa-miR-4272	CLIP-seq
MIRT786627	hsa-miR-4328	CLIP-seq
MIRT786628	hsa-miR-4672	CLIP-seq
MIRT2172440	hsa-miR-548a-5p	CLIP-seq
MIRT2172441	hsa-miR-548ab	CLIP-seq
MIRT2172442	hsa-miR-548ak	CLIP-seq
MIRT2172443	hsa-miR-548b-5p	CLIP-seq
MIRT2172444	hsa-miR-548c-5p	CLIP-seq
MIRT2172445	hsa-miR-548d-5p	CLIP-seq
MIRT2172446	hsa-miR-548h	CLIP-seq
MIRT2172447	hsa-miR-548i	CLIP-seq
MIRT2172448	hsa-miR-548j	CLIP-seq
MIRT2172449	hsa-miR-548k	CLIP-seq
MIRT2172450	hsa-miR-548l	CLIP-seq
MIRT2172451	hsa-miR-548w	CLIP-seq
MIRT2172452	hsa-miR-548y	CLIP-seq
MIRT2172453	hsa-miR-559	CLIP-seq
MIRT786624	hsa-miR-570	CLIP-seq
MIRT786629	hsa-miR-603	CLIP-seq
MIRT2172454	hsa-miR-944	CLIP-seq
MIRT2384269	hsa-miR-3919	CLIP-seq
MIRT2384270	hsa-miR-4679	CLIP-seq
MIRT2384271	hsa-miR-4756-3p	CLIP-seq
MIRT786608	hsa-miR-10a	CLIP-seq
MIRT786609	hsa-miR-10b	CLIP-seq
MIRT2475367	hsa-miR-1183	CLIP-seq
MIRT786610	hsa-miR-124	CLIP-seq
MIRT786611	hsa-miR-1252	CLIP-seq
MIRT2475368	hsa-miR-1273f	CLIP-seq
MIRT2475369	hsa-miR-135a	CLIP-seq
MIRT2475370	hsa-miR-135b	CLIP-seq
MIRT786612	hsa-miR-137	CLIP-seq
MIRT2475371	hsa-miR-143	CLIP-seq
MIRT2475372	hsa-miR-190	CLIP-seq
MIRT2475373	hsa-miR-190b	CLIP-seq
MIRT786613	hsa-miR-19a	CLIP-seq
MIRT786614	hsa-miR-19b	CLIP-seq
MIRT2475374	hsa-miR-200b	CLIP-seq
MIRT2475375	hsa-miR-200c	CLIP-seq
MIRT2475376	hsa-miR-219-5p	CLIP-seq
MIRT2475377	hsa-miR-297	CLIP-seq
MIRT2475378	hsa-miR-299-3p	CLIP-seq
MIRT2475379	hsa-miR-299-5p	CLIP-seq
MIRT2475380	hsa-miR-3064-3p	CLIP-seq
MIRT2475381	hsa-miR-3119	CLIP-seq
MIRT2475382	hsa-miR-3123	CLIP-seq
MIRT786615	hsa-miR-3145-3p	CLIP-seq
MIRT2475383	hsa-miR-3149	CLIP-seq
MIRT2475384	hsa-miR-3163	CLIP-seq
MIRT2475385	hsa-miR-3190	CLIP-seq
MIRT786616	hsa-miR-3194-3p	CLIP-seq
MIRT786617	hsa-miR-323-3p	CLIP-seq
MIRT2475386	hsa-miR-3662	CLIP-seq
MIRT786618	hsa-miR-3665	CLIP-seq
MIRT2475387	hsa-miR-3668	CLIP-seq
MIRT2475388	hsa-miR-3689a-5p	CLIP-seq
MIRT2475389	hsa-miR-3689b	CLIP-seq
MIRT2475390	hsa-miR-3689e	CLIP-seq
MIRT2475391	hsa-miR-3689f	CLIP-seq
MIRT786619	hsa-miR-3714	CLIP-seq
MIRT786620	hsa-miR-3910	CLIP-seq
MIRT2475392	hsa-miR-3923	CLIP-seq
MIRT2475393	hsa-miR-3925-5p	CLIP-seq
MIRT2475394	hsa-miR-3978	CLIP-seq
MIRT2475395	hsa-miR-4282	CLIP-seq
MIRT2475396	hsa-miR-4289	CLIP-seq
MIRT2475397	hsa-miR-429	CLIP-seq
MIRT786621	hsa-miR-4317	CLIP-seq
MIRT2475398	hsa-miR-4423-3p	CLIP-seq
MIRT2475399	hsa-miR-4445	CLIP-seq
MIRT2475400	hsa-miR-4452	CLIP-seq
MIRT2475401	hsa-miR-4491	CLIP-seq
MIRT2475402	hsa-miR-4495	CLIP-seq
MIRT2475403	hsa-miR-4657	CLIP-seq
MIRT2475404	hsa-miR-4693-5p	CLIP-seq
MIRT2475405	hsa-miR-4698	CLIP-seq
MIRT2475406	hsa-miR-4708-5p	CLIP-seq
MIRT2475407	hsa-miR-4732-5p	CLIP-seq
MIRT2475408	hsa-miR-4738-3p	CLIP-seq
MIRT2475409	hsa-miR-4770	CLIP-seq
MIRT2475410	hsa-miR-4777-5p	CLIP-seq
MIRT2475411	hsa-miR-4782-3p	CLIP-seq
MIRT2475412	hsa-miR-493	CLIP-seq
MIRT786622	hsa-miR-506	CLIP-seq
MIRT2475413	hsa-miR-508-3p	CLIP-seq
MIRT2475414	hsa-miR-518d-5p	CLIP-seq
MIRT2475415	hsa-miR-519b-5p	CLIP-seq
MIRT2475416	hsa-miR-519c-5p	CLIP-seq
MIRT2475417	hsa-miR-520c-5p	CLIP-seq
MIRT2475418	hsa-miR-520d-5p	CLIP-seq
MIRT2475419	hsa-miR-524-5p	CLIP-seq
MIRT2475420	hsa-miR-526a	CLIP-seq
MIRT2475421	hsa-miR-548m	CLIP-seq
MIRT2475422	hsa-miR-567	CLIP-seq
MIRT2475423	hsa-miR-576-3p	CLIP-seq
MIRT786625	hsa-miR-616	CLIP-seq
MIRT2475424	hsa-miR-628-3p	CLIP-seq
MIRT786626	hsa-miR-657	CLIP-seq
MIRT2172454	hsa-miR-944	CLIP-seq
MIRT786608	hsa-miR-10a	CLIP-seq
MIRT786609	hsa-miR-10b	CLIP-seq
MIRT2475367	hsa-miR-1183	CLIP-seq
MIRT786610	hsa-miR-124	CLIP-seq
MIRT786611	hsa-miR-1252	CLIP-seq
MIRT2475368	hsa-miR-1273f	CLIP-seq
MIRT2475369	hsa-miR-135a	CLIP-seq
MIRT2475370	hsa-miR-135b	CLIP-seq
MIRT786612	hsa-miR-137	CLIP-seq
MIRT2475371	hsa-miR-143	CLIP-seq
MIRT2475372	hsa-miR-190	CLIP-seq
MIRT2475373	hsa-miR-190b	CLIP-seq
MIRT786613	hsa-miR-19a	CLIP-seq
MIRT786614	hsa-miR-19b	CLIP-seq
MIRT2475374	hsa-miR-200b	CLIP-seq
MIRT2475375	hsa-miR-200c	CLIP-seq
MIRT2475376	hsa-miR-219-5p	CLIP-seq
MIRT2475377	hsa-miR-297	CLIP-seq
MIRT2475378	hsa-miR-299-3p	CLIP-seq
MIRT2475379	hsa-miR-299-5p	CLIP-seq
MIRT2475380	hsa-miR-3064-3p	CLIP-seq
MIRT2475381	hsa-miR-3119	CLIP-seq
MIRT2475382	hsa-miR-3123	CLIP-seq
MIRT786615	hsa-miR-3145-3p	CLIP-seq
MIRT2475383	hsa-miR-3149	CLIP-seq
MIRT2475384	hsa-miR-3163	CLIP-seq
MIRT2475385	hsa-miR-3190	CLIP-seq
MIRT786616	hsa-miR-3194-3p	CLIP-seq
MIRT786617	hsa-miR-323-3p	CLIP-seq
MIRT2475386	hsa-miR-3662	CLIP-seq
MIRT786618	hsa-miR-3665	CLIP-seq
MIRT2475387	hsa-miR-3668	CLIP-seq
MIRT2475388	hsa-miR-3689a-5p	CLIP-seq
MIRT2475389	hsa-miR-3689b	CLIP-seq
MIRT2475390	hsa-miR-3689e	CLIP-seq
MIRT2475391	hsa-miR-3689f	CLIP-seq
MIRT786619	hsa-miR-3714	CLIP-seq
MIRT786620	hsa-miR-3910	CLIP-seq
MIRT2475392	hsa-miR-3923	CLIP-seq
MIRT2475393	hsa-miR-3925-5p	CLIP-seq
MIRT2475394	hsa-miR-3978	CLIP-seq
MIRT2475395	hsa-miR-4282	CLIP-seq
MIRT2475396	hsa-miR-4289	CLIP-seq
MIRT2475397	hsa-miR-429	CLIP-seq
MIRT786621	hsa-miR-4317	CLIP-seq
MIRT2475398	hsa-miR-4423-3p	CLIP-seq
MIRT2475399	hsa-miR-4445	CLIP-seq
MIRT2475400	hsa-miR-4452	CLIP-seq
MIRT2475401	hsa-miR-4491	CLIP-seq
MIRT2475402	hsa-miR-4495	CLIP-seq
MIRT2475403	hsa-miR-4657	CLIP-seq
MIRT2475404	hsa-miR-4693-5p	CLIP-seq
MIRT2475405	hsa-miR-4698	CLIP-seq
MIRT2475406	hsa-miR-4708-5p	CLIP-seq
MIRT2475407	hsa-miR-4732-5p	CLIP-seq
MIRT2475408	hsa-miR-4738-3p	CLIP-seq
MIRT2475409	hsa-miR-4770	CLIP-seq
MIRT2475410	hsa-miR-4777-5p	CLIP-seq
MIRT2475411	hsa-miR-4782-3p	CLIP-seq
MIRT2475412	hsa-miR-493	CLIP-seq
MIRT786622	hsa-miR-506	CLIP-seq
MIRT2475413	hsa-miR-508-3p	CLIP-seq
MIRT2475414	hsa-miR-518d-5p	CLIP-seq
MIRT2475415	hsa-miR-519b-5p	CLIP-seq
MIRT2475416	hsa-miR-519c-5p	CLIP-seq
MIRT2475417	hsa-miR-520c-5p	CLIP-seq
MIRT2475418	hsa-miR-520d-5p	CLIP-seq
MIRT2475419	hsa-miR-524-5p	CLIP-seq
MIRT2475420	hsa-miR-526a	CLIP-seq
MIRT2475421	hsa-miR-548m	CLIP-seq
MIRT2475422	hsa-miR-567	CLIP-seq
MIRT2475423	hsa-miR-576-3p	CLIP-seq
MIRT786625	hsa-miR-616	CLIP-seq
MIRT2475424	hsa-miR-628-3p	CLIP-seq
MIRT786626	hsa-miR-657	CLIP-seq
MIRT2172454	hsa-miR-944	CLIP-seq

Show/Hide all(20)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22681889
GO:0005178	Function	Integrin binding	IPI	24007983
GO:0005509	Function	Calcium ion binding	IBA	21873635
GO:0005515	Function	Protein binding	IPI	9268363, 12445460, 17699613, 18256029
GO:0005544	Function	Calcium-dependent phospholipid binding	IEA
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005634	Component	Nucleus	IDA	10672515
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0005789	Component	Endoplasmic reticulum membrane	IDA	10672515
GO:0006914	Process	Autophagy	IMP	24007983
GO:0010629	Process	Negative regulation of gene expression	IMP	24007983
GO:0014070	Process	Response to organic cyclic compound	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0030855	Process	Epithelial cell differentiation	IEP	21492153
GO:0042584	Component	Chromaffin granule membrane	IDA	9268363
GO:0048306	Function	Calcium-dependent protein binding	IPI	12445460
GO:0051592	Process	Response to calcium ion	IEA
GO:0061025	Process	Membrane fusion	IEA
GO:0062023	Component	Collagen-containing extracellular matrix	HDA	25037231
GO:0070062	Component	Extracellular exosome	HDA	19056867, 19199708, 20458337, 23533145

MIM	HGNC	e!Ensembl
186360	545	ENSG00000138279

Protein

UniProt ID

P20073

Protein name

Annexin A7 (Annexin VII) (Annexin-7) (Synexin)

Protein function

Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.

PDB

8W5S

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00191	Annexin	189 → 254	Annexin	Family
PF00191	Annexin	261 → 326	Annexin	Family
PF00191	Annexin	344 → 410	Annexin	Family
PF00191	Annexin	420 → 485	Annexin	Family

Sequence

MSYPGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGY
PAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQV
PLPGGFPGGQMPSQYPGGQPTYPSQINTDSFSSYPVFSPVSLDYSSEPATVTQVTQGTIR
PAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLK
SELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQ
SEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLGTD
ESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAF
FAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRR
LLLAIVGQ

Sequence length

488

Interactions

View interactions

	KEGG
	Amyotrophic lateral sclerosis

Associated diseases

Show/Hide Unknown Diseases (2)

Unknown
Disease name	Disease term	dbSNP ID	References
Liver neoplasms	Liver neoplasms		25058030
Liver cancer	Malignant neoplasm of liver		25058030

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