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HK2 (hexokinase 2)

Gene

3099

Hexokinase 2

HK2

HKII, HXK2

2p12

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expres

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miRTarBase ID	miRNA	Experiments	Reference
MIRT006301	hsa-miR-143-3p	Luciferase reporter assay	22354042
MIRT006301	hsa-miR-143-3p	Luciferase reporter assay	22354042
MIRT006301	hsa-miR-143-3p	Luciferase reporter assay	22354042
MIRT006301	hsa-miR-143-3p	Luciferase reporter assay	22354042
MIRT006301	hsa-miR-143-3p	Luciferase reporter assay	22354042
MIRT006301	hsa-miR-143-3p	Luciferase reporter assay	22354042
MIRT006301	hsa-miR-143-3p	Luciferase reporter assay	22691140
MIRT006301	hsa-miR-143-3p	Luciferase reporter assay	22691140
MIRT006301	hsa-miR-143-3p	Luciferase reporter assay	22691140
MIRT006301	hsa-miR-143-3p	Luciferase reporter assay	22691140
MIRT006301	hsa-miR-143-3p	Luciferase reporter assay	22593586
MIRT006301	hsa-miR-143-3p	Luciferase reporter assay	22593586
MIRT006944	hsa-miR-125a-5p	Luciferase reporter assay	22593586
MIRT006944	hsa-miR-125a-5p	Luciferase reporter assay	22593586
MIRT006945	hsa-miR-125b-5p	Luciferase reporter assay, qRT-PCR	22593586
MIRT006301	hsa-miR-143-3p	Luciferase reporter assay	23376635
MIRT006301	hsa-miR-143-3p	Luciferase reporter assay	23376635
MIRT019914	hsa-miR-375	Microarray	20215506
MIRT020800	hsa-miR-155-5p	Proteomics	18668040
MIRT027665	hsa-miR-98-5p	Microarray	19088304
MIRT041885	hsa-miR-484	CLASH	23622248
MIRT041885	hsa-miR-484	CLASH	23622248
MIRT006301	hsa-miR-143-3p	Luciferase reporter assay, qRT-PCR, Western blot	24033605
0	hsa-miR-143-3p	Luciferase reporter assay, qRT-PCR, Western blot	24033605
MIRT440498	ebv-miR-BART13-3p	HITS-CLIP	22473208
MIRT440498	ebv-miR-BART13-3p	HITS-CLIP	22473208
MIRT731381	hsa-miR-199a-5p	Luciferase reporter assay, qRT-PCR, Western blot	26054020
MIRT731381	hsa-miR-199a-5p	Luciferase reporter assay, qRT-PCR, Western blot	26054020
MIRT731659	hsa-miR-181b-5p	Immunohistochemistry, In situ hybridization, Luciferase reporter assay, qRT-PCR, Western blot	28184935
MIRT731659	hsa-miR-181b-5p	Immunohistochemistry, In situ hybridization, Luciferase reporter assay, qRT-PCR, Western blot	28184935
MIRT027665	hsa-miR-98-5p	SW620	28025745
MIRT731659	hsa-miR-181b-5p	Luciferase reporter assay, qRT-PCR, Western blot	27314295
MIRT731659	hsa-miR-181b-5p	Luciferase reporter assay, qRT-PCR, Western blot	27314295
MIRT732439	hsa-miR-487a-3p	Luciferase reporter assay, Microarray, Western blotting	32094325
MIRT733345	hsa-miR-199b-3p	Immunoprecipitaion (IP), Luciferase reporter assay, qRT-PCR, Western blotting	34257820
MIRT734062	hsa-miR-505-3p	Immunoprecipitaion (IP), Luciferase reporter assay, qRT-PCR, Western blotting	33520999
MIRT006945	hsa-miR-125b-5p	Luciferase reporter assay, Western blotting, qRT-PCR	32415544
MIRT736637	hsa-miR-513a-5p	Luciferase reporter assay, Western blotting, qRT-PCR	32537015
MIRT736638	hsa-miR-513a-3p	Luciferase reporter assay, Western blotting, qRT-PCR	32537015
MIRT737175	hsa-miR-3143	RNA-seq	33425736
MIRT737334	hsa-miR-202-3p	Luciferase reporter assay, Western blotting, qRT-PCR	32194725
MIRT737466	hsa-miR-374b-5p	Western blotting, RNA-seq, qRT-PCR	31878355
MIRT755692	hsa-miR-603	Western blotting, qRT-PCR, in vitro cullelar assays	35770296
MIRT006301	hsa-miR-143-3p	Luciferase reporter assay, Western blotting, qRT-PCR, RNA pull down assay	35070838
MIRT756061	hsa-miR-145-5p	Luciferase reporter assay, Western blotting, qRT-PCR, RNA pull down assay	38010958
MIRT1048076	hsa-miR-1202	CLIP-seq
MIRT1048077	hsa-miR-125b	CLIP-seq
MIRT1048078	hsa-miR-1271	CLIP-seq
MIRT1048079	hsa-miR-1273f	CLIP-seq
MIRT1048080	hsa-miR-1275	CLIP-seq
MIRT1048081	hsa-miR-1276	CLIP-seq
MIRT1048082	hsa-miR-1286	CLIP-seq
MIRT1048083	hsa-miR-130a	CLIP-seq
MIRT1048084	hsa-miR-130b	CLIP-seq
MIRT1048085	hsa-miR-140-3p	CLIP-seq
MIRT1048086	hsa-miR-143	CLIP-seq
MIRT1048087	hsa-miR-146a	CLIP-seq
MIRT1048088	hsa-miR-146b-5p	CLIP-seq
MIRT1048089	hsa-miR-148a	CLIP-seq
MIRT1048090	hsa-miR-148b	CLIP-seq
MIRT1048091	hsa-miR-151-3p	CLIP-seq
MIRT1048092	hsa-miR-152	CLIP-seq
MIRT1048093	hsa-miR-181a	CLIP-seq
MIRT1048094	hsa-miR-181b	CLIP-seq
MIRT1048095	hsa-miR-181c	CLIP-seq
MIRT1048096	hsa-miR-181d	CLIP-seq
MIRT1048097	hsa-miR-182	CLIP-seq
MIRT1048098	hsa-miR-185	CLIP-seq
MIRT1048099	hsa-miR-2114	CLIP-seq
MIRT1048100	hsa-miR-214	CLIP-seq
MIRT1048101	hsa-miR-218	CLIP-seq
MIRT1048102	hsa-miR-300	CLIP-seq
MIRT1048103	hsa-miR-301a	CLIP-seq
MIRT1048104	hsa-miR-301b	CLIP-seq
MIRT1048105	hsa-miR-31	CLIP-seq
MIRT1048106	hsa-miR-3124-3p	CLIP-seq
MIRT1048107	hsa-miR-3125	CLIP-seq
MIRT1048108	hsa-miR-3135	CLIP-seq
MIRT1048109	hsa-miR-3148	CLIP-seq
MIRT1048110	hsa-miR-3149	CLIP-seq
MIRT1048111	hsa-miR-3161	CLIP-seq
MIRT1048112	hsa-miR-3173-3p	CLIP-seq
MIRT1048113	hsa-miR-3184	CLIP-seq
MIRT1048114	hsa-miR-3185	CLIP-seq
MIRT1048115	hsa-miR-3194-5p	CLIP-seq
MIRT1048116	hsa-miR-3199	CLIP-seq
MIRT1048117	hsa-miR-323-3p	CLIP-seq
MIRT1048118	hsa-miR-3619-5p	CLIP-seq
MIRT1048119	hsa-miR-362-5p	CLIP-seq
MIRT1048120	hsa-miR-3660	CLIP-seq
MIRT1048121	hsa-miR-3666	CLIP-seq
MIRT1048122	hsa-miR-3674	CLIP-seq
MIRT1048123	hsa-miR-3713	CLIP-seq
MIRT1048124	hsa-miR-374a	CLIP-seq
MIRT1048125	hsa-miR-374b	CLIP-seq
MIRT1048126	hsa-miR-381	CLIP-seq
MIRT1048127	hsa-miR-3913-3p	CLIP-seq
MIRT1048128	hsa-miR-3916	CLIP-seq
MIRT1048129	hsa-miR-3935	CLIP-seq
MIRT1048130	hsa-miR-3972	CLIP-seq
MIRT1048131	hsa-miR-409-3p	CLIP-seq
MIRT1048132	hsa-miR-412	CLIP-seq
MIRT1048133	hsa-miR-423-5p	CLIP-seq
MIRT1048134	hsa-miR-4251	CLIP-seq
MIRT1048135	hsa-miR-4256	CLIP-seq
MIRT1048136	hsa-miR-4262	CLIP-seq
MIRT1048137	hsa-miR-4267	CLIP-seq
MIRT1048138	hsa-miR-4271	CLIP-seq
MIRT1048139	hsa-miR-4275	CLIP-seq
MIRT1048140	hsa-miR-4282	CLIP-seq
MIRT1048141	hsa-miR-4291	CLIP-seq
MIRT1048142	hsa-miR-4295	CLIP-seq
MIRT1048143	hsa-miR-4300	CLIP-seq
MIRT1048144	hsa-miR-4303	CLIP-seq
MIRT1048145	hsa-miR-4306	CLIP-seq
MIRT1048146	hsa-miR-4311	CLIP-seq
MIRT1048147	hsa-miR-4319	CLIP-seq
MIRT1048148	hsa-miR-4329	CLIP-seq
MIRT1048149	hsa-miR-4428	CLIP-seq
MIRT1048150	hsa-miR-4436b-5p	CLIP-seq
MIRT1048151	hsa-miR-4450	CLIP-seq
MIRT1048152	hsa-miR-4463	CLIP-seq
MIRT1048153	hsa-miR-4473	CLIP-seq
MIRT1048154	hsa-miR-4475	CLIP-seq
MIRT1048155	hsa-miR-4499	CLIP-seq
MIRT1048156	hsa-miR-450b-5p	CLIP-seq
MIRT1048157	hsa-miR-4525	CLIP-seq
MIRT1048158	hsa-miR-4526	CLIP-seq
MIRT1048159	hsa-miR-4533	CLIP-seq
MIRT1048160	hsa-miR-454	CLIP-seq
MIRT1048161	hsa-miR-4644	CLIP-seq
MIRT1048162	hsa-miR-4646-3p	CLIP-seq
MIRT1048163	hsa-miR-4665-5p	CLIP-seq
MIRT1048164	hsa-miR-4666-3p	CLIP-seq
MIRT1048165	hsa-miR-4671-3p	CLIP-seq
MIRT1048166	hsa-miR-4680-5p	CLIP-seq
MIRT1048167	hsa-miR-4687-3p	CLIP-seq
MIRT1048168	hsa-miR-4698	CLIP-seq
MIRT1048169	hsa-miR-4708-5p	CLIP-seq
MIRT1048170	hsa-miR-4714-3p	CLIP-seq
MIRT1048171	hsa-miR-4716-3p	CLIP-seq
MIRT1048172	hsa-miR-4717-3p	CLIP-seq
MIRT1048173	hsa-miR-4722-5p	CLIP-seq
MIRT1048174	hsa-miR-4723-5p	CLIP-seq
MIRT1048175	hsa-miR-4725-3p	CLIP-seq
MIRT1048176	hsa-miR-4731-5p	CLIP-seq
MIRT1048177	hsa-miR-4732-3p	CLIP-seq
MIRT1048178	hsa-miR-4747-5p	CLIP-seq
MIRT1048179	hsa-miR-4762-3p	CLIP-seq
MIRT1048180	hsa-miR-4768-3p	CLIP-seq
MIRT1048181	hsa-miR-4770	CLIP-seq
MIRT1048182	hsa-miR-4802-3p	CLIP-seq
MIRT1048183	hsa-miR-4803	CLIP-seq
MIRT1048184	hsa-miR-487a	CLIP-seq
MIRT1048185	hsa-miR-489	CLIP-seq
MIRT1048186	hsa-miR-495	CLIP-seq
MIRT1048187	hsa-miR-500b	CLIP-seq
MIRT1048188	hsa-miR-505	CLIP-seq
MIRT1048189	hsa-miR-507	CLIP-seq
MIRT1048190	hsa-miR-512-3p	CLIP-seq
MIRT1048191	hsa-miR-543	CLIP-seq
MIRT1048192	hsa-miR-544b	CLIP-seq
MIRT1048193	hsa-miR-548aa	CLIP-seq
MIRT1048194	hsa-miR-548ac	CLIP-seq
MIRT1048195	hsa-miR-548d-3p	CLIP-seq
MIRT1048196	hsa-miR-548z	CLIP-seq
MIRT1048197	hsa-miR-549	CLIP-seq
MIRT1048198	hsa-miR-557	CLIP-seq
MIRT1048199	hsa-miR-583	CLIP-seq
MIRT1048200	hsa-miR-587	CLIP-seq
MIRT1048201	hsa-miR-589	CLIP-seq
MIRT1048202	hsa-miR-591	CLIP-seq
MIRT1048203	hsa-miR-618	CLIP-seq
MIRT1048204	hsa-miR-625	CLIP-seq
MIRT1048205	hsa-miR-633	CLIP-seq
MIRT1048206	hsa-miR-636	CLIP-seq
MIRT1048207	hsa-miR-637	CLIP-seq
MIRT1048208	hsa-miR-642a	CLIP-seq
MIRT1048209	hsa-miR-643	CLIP-seq
MIRT1048210	hsa-miR-647	CLIP-seq
MIRT1048211	hsa-miR-654-3p	CLIP-seq
MIRT1048212	hsa-miR-664	CLIP-seq
MIRT1048213	hsa-miR-670	CLIP-seq
MIRT1048214	hsa-miR-761	CLIP-seq
MIRT1048215	hsa-miR-765	CLIP-seq
MIRT1048216	hsa-miR-802	CLIP-seq
MIRT1048217	hsa-miR-920	CLIP-seq
MIRT1048218	hsa-miR-922	CLIP-seq
MIRT1048219	hsa-miR-96	CLIP-seq
MIRT1048209	hsa-miR-643	CLIP-seq
MIRT1922098	hsa-miR-3675-3p	CLIP-seq
MIRT1922099	hsa-miR-4684-5p	CLIP-seq
MIRT2010904	hsa-miR-1185	CLIP-seq
MIRT2010905	hsa-miR-1224-5p	CLIP-seq
MIRT2010906	hsa-miR-1251	CLIP-seq
MIRT1048082	hsa-miR-1286	CLIP-seq
MIRT1048083	hsa-miR-130a	CLIP-seq
MIRT1048084	hsa-miR-130b	CLIP-seq
MIRT1048086	hsa-miR-143	CLIP-seq
MIRT2010907	hsa-miR-145	CLIP-seq
MIRT1048087	hsa-miR-146a	CLIP-seq
MIRT1048088	hsa-miR-146b-5p	CLIP-seq
MIRT2010908	hsa-miR-15a	CLIP-seq
MIRT2010909	hsa-miR-15b	CLIP-seq
MIRT2010910	hsa-miR-16	CLIP-seq
MIRT1048093	hsa-miR-181a	CLIP-seq
MIRT1048094	hsa-miR-181b	CLIP-seq
MIRT1048095	hsa-miR-181c	CLIP-seq
MIRT1048096	hsa-miR-181d	CLIP-seq
MIRT2010911	hsa-miR-1825	CLIP-seq
MIRT1048098	hsa-miR-185	CLIP-seq
MIRT2010912	hsa-miR-195	CLIP-seq
MIRT2010913	hsa-miR-199b-5p	CLIP-seq
MIRT2010914	hsa-miR-200b	CLIP-seq
MIRT2010915	hsa-miR-200c	CLIP-seq
MIRT1048099	hsa-miR-2114	CLIP-seq
MIRT2010916	hsa-miR-216b	CLIP-seq
MIRT2010917	hsa-miR-2467-3p	CLIP-seq
MIRT1048103	hsa-miR-301a	CLIP-seq
MIRT1048104	hsa-miR-301b	CLIP-seq
MIRT1048107	hsa-miR-3125	CLIP-seq
MIRT2010918	hsa-miR-3155	CLIP-seq
MIRT2010919	hsa-miR-3155b	CLIP-seq
MIRT2010920	hsa-miR-3159	CLIP-seq
MIRT2010921	hsa-miR-3180-5p	CLIP-seq
MIRT1048114	hsa-miR-3185	CLIP-seq
MIRT2010922	hsa-miR-3192	CLIP-seq
MIRT1048116	hsa-miR-3199	CLIP-seq
MIRT2010923	hsa-miR-330-3p	CLIP-seq
MIRT2010924	hsa-miR-3605-5p	CLIP-seq
MIRT1048120	hsa-miR-3660	CLIP-seq
MIRT1048121	hsa-miR-3666	CLIP-seq
MIRT2010925	hsa-miR-3671	CLIP-seq
MIRT1922098	hsa-miR-3675-3p	CLIP-seq
MIRT2010926	hsa-miR-3679-5p	CLIP-seq
MIRT2010927	hsa-miR-3689a-3p	CLIP-seq
MIRT2010928	hsa-miR-3689c	CLIP-seq
MIRT1048124	hsa-miR-374a	CLIP-seq
MIRT1048125	hsa-miR-374b	CLIP-seq
MIRT1048127	hsa-miR-3913-3p	CLIP-seq
MIRT2010929	hsa-miR-3915	CLIP-seq
MIRT1048128	hsa-miR-3916	CLIP-seq
MIRT2010930	hsa-miR-3921	CLIP-seq
MIRT2010931	hsa-miR-3941	CLIP-seq
MIRT2010932	hsa-miR-424	CLIP-seq
MIRT1048134	hsa-miR-4251	CLIP-seq
MIRT2010933	hsa-miR-4255	CLIP-seq
MIRT1048136	hsa-miR-4262	CLIP-seq
MIRT1048140	hsa-miR-4282	CLIP-seq
MIRT2010934	hsa-miR-429	CLIP-seq
MIRT1048142	hsa-miR-4295	CLIP-seq
MIRT1048143	hsa-miR-4300	CLIP-seq
MIRT1048144	hsa-miR-4303	CLIP-seq
MIRT1048145	hsa-miR-4306	CLIP-seq
MIRT2010935	hsa-miR-4326	CLIP-seq
MIRT1048148	hsa-miR-4329	CLIP-seq
MIRT1048149	hsa-miR-4428	CLIP-seq
MIRT2010936	hsa-miR-4437	CLIP-seq
MIRT2010937	hsa-miR-4457	CLIP-seq
MIRT2010938	hsa-miR-4461	CLIP-seq
MIRT1048153	hsa-miR-4473	CLIP-seq
MIRT1048154	hsa-miR-4475	CLIP-seq
MIRT1048158	hsa-miR-4526	CLIP-seq
MIRT2010939	hsa-miR-4534	CLIP-seq
MIRT1048160	hsa-miR-454	CLIP-seq
MIRT1048161	hsa-miR-4644	CLIP-seq
MIRT2010940	hsa-miR-4653-5p	CLIP-seq
MIRT2010941	hsa-miR-466	CLIP-seq
MIRT1048165	hsa-miR-4671-3p	CLIP-seq
MIRT2010942	hsa-miR-4672	CLIP-seq
MIRT1048167	hsa-miR-4687-3p	CLIP-seq
MIRT2010943	hsa-miR-4689	CLIP-seq
MIRT2010944	hsa-miR-4699-3p	CLIP-seq
MIRT1048169	hsa-miR-4708-5p	CLIP-seq
MIRT1048170	hsa-miR-4714-3p	CLIP-seq
MIRT2010945	hsa-miR-4721	CLIP-seq
MIRT1048173	hsa-miR-4722-5p	CLIP-seq
MIRT2010946	hsa-miR-4728-5p	CLIP-seq
MIRT2010947	hsa-miR-4731-3p	CLIP-seq
MIRT1048176	hsa-miR-4731-5p	CLIP-seq
MIRT2010948	hsa-miR-4742-3p	CLIP-seq
MIRT1048180	hsa-miR-4768-3p	CLIP-seq
MIRT1048181	hsa-miR-4770	CLIP-seq
MIRT2010949	hsa-miR-4777-5p	CLIP-seq
MIRT2010950	hsa-miR-4801	CLIP-seq
MIRT2010951	hsa-miR-4802-5p	CLIP-seq
MIRT1048183	hsa-miR-4803	CLIP-seq
MIRT1048185	hsa-miR-489	CLIP-seq
MIRT1048186	hsa-miR-495	CLIP-seq
MIRT2010952	hsa-miR-497	CLIP-seq
MIRT1048188	hsa-miR-505	CLIP-seq
MIRT1048191	hsa-miR-543	CLIP-seq
MIRT2010953	hsa-miR-545	CLIP-seq
MIRT1048194	hsa-miR-548ac	CLIP-seq
MIRT1048195	hsa-miR-548d-3p	CLIP-seq
MIRT1048196	hsa-miR-548z	CLIP-seq
MIRT1048199	hsa-miR-583	CLIP-seq
MIRT1048201	hsa-miR-589	CLIP-seq
MIRT2010954	hsa-miR-642b	CLIP-seq
MIRT2010955	hsa-miR-653	CLIP-seq
MIRT2010956	hsa-miR-659	CLIP-seq
MIRT1048215	hsa-miR-765	CLIP-seq
MIRT2010957	hsa-miR-769-5p	CLIP-seq
MIRT1048217	hsa-miR-920	CLIP-seq
MIRT1048218	hsa-miR-922	CLIP-seq
MIRT1048076	hsa-miR-1202	CLIP-seq
MIRT2243140	hsa-miR-1236	CLIP-seq
MIRT1048078	hsa-miR-1271	CLIP-seq
MIRT1048079	hsa-miR-1273f	CLIP-seq
MIRT1048080	hsa-miR-1275	CLIP-seq
MIRT1048083	hsa-miR-130a	CLIP-seq
MIRT1048084	hsa-miR-130b	CLIP-seq
MIRT2243141	hsa-miR-1324	CLIP-seq
MIRT1048085	hsa-miR-140-3p	CLIP-seq
MIRT1048086	hsa-miR-143	CLIP-seq
MIRT1048089	hsa-miR-148a	CLIP-seq
MIRT1048090	hsa-miR-148b	CLIP-seq
MIRT1048091	hsa-miR-151-3p	CLIP-seq
MIRT1048092	hsa-miR-152	CLIP-seq
MIRT2010908	hsa-miR-15a	CLIP-seq
MIRT2010909	hsa-miR-15b	CLIP-seq
MIRT2010910	hsa-miR-16	CLIP-seq
MIRT1048097	hsa-miR-182	CLIP-seq
MIRT1048098	hsa-miR-185	CLIP-seq
MIRT2010912	hsa-miR-195	CLIP-seq
MIRT1048099	hsa-miR-2114	CLIP-seq
MIRT2010917	hsa-miR-2467-3p	CLIP-seq
MIRT2243142	hsa-miR-28-5p	CLIP-seq
MIRT1048103	hsa-miR-301a	CLIP-seq
MIRT1048104	hsa-miR-301b	CLIP-seq
MIRT2243143	hsa-miR-3065-3p	CLIP-seq
MIRT1048105	hsa-miR-31	CLIP-seq
MIRT2243144	hsa-miR-3117-5p	CLIP-seq
MIRT2243145	hsa-miR-3119	CLIP-seq
MIRT2243146	hsa-miR-3121-5p	CLIP-seq
MIRT1048107	hsa-miR-3125	CLIP-seq
MIRT1048108	hsa-miR-3135	CLIP-seq
MIRT2243147	hsa-miR-3139	CLIP-seq
MIRT2010918	hsa-miR-3155	CLIP-seq
MIRT2010919	hsa-miR-3155b	CLIP-seq
MIRT1048111	hsa-miR-3161	CLIP-seq
MIRT1048112	hsa-miR-3173-3p	CLIP-seq
MIRT1048114	hsa-miR-3185	CLIP-seq
MIRT2010922	hsa-miR-3192	CLIP-seq
MIRT1048115	hsa-miR-3194-5p	CLIP-seq
MIRT1048117	hsa-miR-323-3p	CLIP-seq
MIRT2010923	hsa-miR-330-3p	CLIP-seq
MIRT2243148	hsa-miR-3591-5p	CLIP-seq
MIRT2243149	hsa-miR-3655	CLIP-seq
MIRT2243150	hsa-miR-3657	CLIP-seq
MIRT1048120	hsa-miR-3660	CLIP-seq
MIRT1048121	hsa-miR-3666	CLIP-seq
MIRT2010925	hsa-miR-3671	CLIP-seq
MIRT2010927	hsa-miR-3689a-3p	CLIP-seq
MIRT2010928	hsa-miR-3689c	CLIP-seq
MIRT1048128	hsa-miR-3916	CLIP-seq
MIRT2010931	hsa-miR-3941	CLIP-seq
MIRT1048130	hsa-miR-3972	CLIP-seq
MIRT1048132	hsa-miR-412	CLIP-seq
MIRT2010932	hsa-miR-424	CLIP-seq
MIRT1048135	hsa-miR-4256	CLIP-seq
MIRT1048137	hsa-miR-4267	CLIP-seq
MIRT1048138	hsa-miR-4271	CLIP-seq
MIRT1048139	hsa-miR-4275	CLIP-seq
MIRT1048140	hsa-miR-4282	CLIP-seq
MIRT2243151	hsa-miR-4286	CLIP-seq
MIRT1048142	hsa-miR-4295	CLIP-seq
MIRT1048143	hsa-miR-4300	CLIP-seq
MIRT1048145	hsa-miR-4306	CLIP-seq
MIRT2243152	hsa-miR-4317	CLIP-seq
MIRT1048149	hsa-miR-4428	CLIP-seq
MIRT2010936	hsa-miR-4437	CLIP-seq
MIRT1048151	hsa-miR-4450	CLIP-seq
MIRT2010938	hsa-miR-4461	CLIP-seq
MIRT1048152	hsa-miR-4463	CLIP-seq
MIRT1048153	hsa-miR-4473	CLIP-seq
MIRT1048155	hsa-miR-4499	CLIP-seq
MIRT1048157	hsa-miR-4525	CLIP-seq
MIRT1048158	hsa-miR-4526	CLIP-seq
MIRT1048159	hsa-miR-4533	CLIP-seq
MIRT1048160	hsa-miR-454	CLIP-seq
MIRT1048161	hsa-miR-4644	CLIP-seq
MIRT2010941	hsa-miR-466	CLIP-seq
MIRT1048163	hsa-miR-4665-5p	CLIP-seq
MIRT1048165	hsa-miR-4671-3p	CLIP-seq
MIRT2010942	hsa-miR-4672	CLIP-seq
MIRT2010944	hsa-miR-4699-3p	CLIP-seq
MIRT1048169	hsa-miR-4708-5p	CLIP-seq
MIRT1048171	hsa-miR-4716-3p	CLIP-seq
MIRT1048172	hsa-miR-4717-3p	CLIP-seq
MIRT2243153	hsa-miR-4720-3p	CLIP-seq
MIRT2010945	hsa-miR-4721	CLIP-seq
MIRT1048174	hsa-miR-4723-5p	CLIP-seq
MIRT1048175	hsa-miR-4725-3p	CLIP-seq
MIRT2010946	hsa-miR-4728-5p	CLIP-seq
MIRT2010947	hsa-miR-4731-3p	CLIP-seq
MIRT1048176	hsa-miR-4731-5p	CLIP-seq
MIRT2010948	hsa-miR-4742-3p	CLIP-seq
MIRT1048178	hsa-miR-4747-5p	CLIP-seq
MIRT2243154	hsa-miR-4761-5p	CLIP-seq
MIRT1048180	hsa-miR-4768-3p	CLIP-seq
MIRT1048181	hsa-miR-4770	CLIP-seq
MIRT2243155	hsa-miR-4789-5p	CLIP-seq
MIRT2243156	hsa-miR-4793-5p	CLIP-seq
MIRT2010950	hsa-miR-4801	CLIP-seq
MIRT1048182	hsa-miR-4802-3p	CLIP-seq
MIRT2243157	hsa-miR-4804-3p	CLIP-seq
MIRT2243158	hsa-miR-486-5p	CLIP-seq
MIRT1048184	hsa-miR-487a	CLIP-seq
MIRT1048186	hsa-miR-495	CLIP-seq
MIRT2010952	hsa-miR-497	CLIP-seq
MIRT2243159	hsa-miR-498	CLIP-seq
MIRT2243160	hsa-miR-501-3p	CLIP-seq
MIRT2243161	hsa-miR-502-3p	CLIP-seq
MIRT1048190	hsa-miR-512-3p	CLIP-seq
MIRT1048199	hsa-miR-583	CLIP-seq
MIRT1048202	hsa-miR-591	CLIP-seq
MIRT1048204	hsa-miR-625	CLIP-seq
MIRT1048207	hsa-miR-637	CLIP-seq
MIRT1048208	hsa-miR-642a	CLIP-seq
MIRT2010956	hsa-miR-659	CLIP-seq
MIRT1048212	hsa-miR-664	CLIP-seq
MIRT2243162	hsa-miR-708	CLIP-seq
MIRT1048215	hsa-miR-765	CLIP-seq
MIRT1048216	hsa-miR-802	CLIP-seq
MIRT2243163	hsa-miR-9	CLIP-seq
MIRT1048217	hsa-miR-920	CLIP-seq
MIRT1048218	hsa-miR-922	CLIP-seq
MIRT1048219	hsa-miR-96	CLIP-seq
MIRT1048087	hsa-miR-146a	CLIP-seq
MIRT1048088	hsa-miR-146b-5p	CLIP-seq
MIRT1048093	hsa-miR-181a	CLIP-seq
MIRT1048094	hsa-miR-181b	CLIP-seq
MIRT1048095	hsa-miR-181c	CLIP-seq
MIRT1048096	hsa-miR-181d	CLIP-seq
MIRT1048134	hsa-miR-4251	CLIP-seq
MIRT1048136	hsa-miR-4262	CLIP-seq
MIRT1048144	hsa-miR-4303	CLIP-seq
MIRT1048148	hsa-miR-4329	CLIP-seq
MIRT1048168	hsa-miR-4698	CLIP-seq
MIRT1048170	hsa-miR-4714-3p	CLIP-seq
MIRT1048183	hsa-miR-4803	CLIP-seq
MIRT1048186	hsa-miR-495	CLIP-seq
MIRT1048188	hsa-miR-505	CLIP-seq
MIRT1048191	hsa-miR-543	CLIP-seq
MIRT1048201	hsa-miR-589	CLIP-seq
MIRT2451219	hsa-miR-3120-5p	CLIP-seq
MIRT2451220	hsa-miR-3936	CLIP-seq
MIRT2451221	hsa-miR-548p	CLIP-seq
MIRT1048080	hsa-miR-1275	CLIP-seq
MIRT2010907	hsa-miR-145	CLIP-seq
MIRT1048087	hsa-miR-146a	CLIP-seq
MIRT1048088	hsa-miR-146b-5p	CLIP-seq
MIRT1048089	hsa-miR-148a	CLIP-seq
MIRT1048090	hsa-miR-148b	CLIP-seq
MIRT1048092	hsa-miR-152	CLIP-seq
MIRT1048093	hsa-miR-181a	CLIP-seq
MIRT1048094	hsa-miR-181b	CLIP-seq
MIRT1048095	hsa-miR-181c	CLIP-seq
MIRT1048096	hsa-miR-181d	CLIP-seq
MIRT2010911	hsa-miR-1825	CLIP-seq
MIRT2010913	hsa-miR-199b-5p	CLIP-seq
MIRT2546381	hsa-miR-2113	CLIP-seq
MIRT2243145	hsa-miR-3119	CLIP-seq
MIRT2546382	hsa-miR-3140-3p	CLIP-seq
MIRT2010918	hsa-miR-3155	CLIP-seq
MIRT2010919	hsa-miR-3155b	CLIP-seq
MIRT2010921	hsa-miR-3180-5p	CLIP-seq
MIRT2546383	hsa-miR-329	CLIP-seq
MIRT2546384	hsa-miR-346	CLIP-seq
MIRT2243148	hsa-miR-3591-5p	CLIP-seq
MIRT2546385	hsa-miR-362-3p	CLIP-seq
MIRT1048120	hsa-miR-3660	CLIP-seq
MIRT1922098	hsa-miR-3675-3p	CLIP-seq
MIRT1048124	hsa-miR-374a	CLIP-seq
MIRT1048125	hsa-miR-374b	CLIP-seq
MIRT2546386	hsa-miR-374c	CLIP-seq
MIRT1048127	hsa-miR-3913-3p	CLIP-seq
MIRT2010930	hsa-miR-3921	CLIP-seq
MIRT2010931	hsa-miR-3941	CLIP-seq
MIRT2546387	hsa-miR-3978	CLIP-seq
MIRT1048134	hsa-miR-4251	CLIP-seq
MIRT2010933	hsa-miR-4255	CLIP-seq
MIRT2546388	hsa-miR-4261	CLIP-seq
MIRT1048136	hsa-miR-4262	CLIP-seq
MIRT1048140	hsa-miR-4282	CLIP-seq
MIRT2546389	hsa-miR-4284	CLIP-seq
MIRT2243151	hsa-miR-4286	CLIP-seq
MIRT1048144	hsa-miR-4303	CLIP-seq
MIRT2010935	hsa-miR-4326	CLIP-seq
MIRT1048148	hsa-miR-4329	CLIP-seq
MIRT2010937	hsa-miR-4457	CLIP-seq
MIRT1048157	hsa-miR-4525	CLIP-seq
MIRT1048158	hsa-miR-4526	CLIP-seq
MIRT2010940	hsa-miR-4653-5p	CLIP-seq
MIRT1048163	hsa-miR-4665-5p	CLIP-seq
MIRT2546390	hsa-miR-4690-5p	CLIP-seq
MIRT1048168	hsa-miR-4698	CLIP-seq
MIRT1048170	hsa-miR-4714-3p	CLIP-seq
MIRT1048174	hsa-miR-4723-5p	CLIP-seq
MIRT2010947	hsa-miR-4731-3p	CLIP-seq
MIRT1048176	hsa-miR-4731-5p	CLIP-seq
MIRT2243154	hsa-miR-4761-5p	CLIP-seq
MIRT1048180	hsa-miR-4768-3p	CLIP-seq
MIRT2010950	hsa-miR-4801	CLIP-seq
MIRT1048183	hsa-miR-4803	CLIP-seq
MIRT1048185	hsa-miR-489	CLIP-seq
MIRT2243160	hsa-miR-501-3p	CLIP-seq
MIRT2243161	hsa-miR-502-3p	CLIP-seq
MIRT1048188	hsa-miR-505	CLIP-seq
MIRT1048190	hsa-miR-512-3p	CLIP-seq
MIRT1048191	hsa-miR-543	CLIP-seq
MIRT1048201	hsa-miR-589	CLIP-seq
MIRT2546391	hsa-miR-599	CLIP-seq
MIRT755692	hsa-miR-603	CLIP-seq
MIRT1048204	hsa-miR-625	CLIP-seq
MIRT1048207	hsa-miR-637	CLIP-seq
MIRT2010954	hsa-miR-642b	CLIP-seq
MIRT2546392	hsa-miR-655	CLIP-seq
MIRT2546393	hsa-miR-662	CLIP-seq
MIRT2010957	hsa-miR-769-5p	CLIP-seq
MIRT1048216	hsa-miR-802	CLIP-seq
MIRT1048080	hsa-miR-1275	CLIP-seq
MIRT2010907	hsa-miR-145	CLIP-seq
MIRT1048087	hsa-miR-146a	CLIP-seq
MIRT1048088	hsa-miR-146b-5p	CLIP-seq
MIRT1048089	hsa-miR-148a	CLIP-seq
MIRT1048090	hsa-miR-148b	CLIP-seq
MIRT1048092	hsa-miR-152	CLIP-seq
MIRT1048093	hsa-miR-181a	CLIP-seq
MIRT1048094	hsa-miR-181b	CLIP-seq
MIRT1048095	hsa-miR-181c	CLIP-seq
MIRT1048096	hsa-miR-181d	CLIP-seq
MIRT2010911	hsa-miR-1825	CLIP-seq
MIRT2010913	hsa-miR-199b-5p	CLIP-seq
MIRT2546381	hsa-miR-2113	CLIP-seq
MIRT2243145	hsa-miR-3119	CLIP-seq
MIRT2546382	hsa-miR-3140-3p	CLIP-seq
MIRT2010918	hsa-miR-3155	CLIP-seq
MIRT2010919	hsa-miR-3155b	CLIP-seq
MIRT2010921	hsa-miR-3180-5p	CLIP-seq
MIRT2546383	hsa-miR-329	CLIP-seq
MIRT2546384	hsa-miR-346	CLIP-seq
MIRT2546385	hsa-miR-362-3p	CLIP-seq
MIRT1048120	hsa-miR-3660	CLIP-seq
MIRT2546386	hsa-miR-374c	CLIP-seq
MIRT2010930	hsa-miR-3921	CLIP-seq
MIRT2010931	hsa-miR-3941	CLIP-seq
MIRT2546387	hsa-miR-3978	CLIP-seq
MIRT1048134	hsa-miR-4251	CLIP-seq
MIRT2010933	hsa-miR-4255	CLIP-seq
MIRT2546388	hsa-miR-4261	CLIP-seq
MIRT1048136	hsa-miR-4262	CLIP-seq
MIRT1048140	hsa-miR-4282	CLIP-seq
MIRT2546389	hsa-miR-4284	CLIP-seq
MIRT2243151	hsa-miR-4286	CLIP-seq
MIRT1048144	hsa-miR-4303	CLIP-seq
MIRT2010935	hsa-miR-4326	CLIP-seq
MIRT1048148	hsa-miR-4329	CLIP-seq
MIRT1048157	hsa-miR-4525	CLIP-seq
MIRT1048158	hsa-miR-4526	CLIP-seq
MIRT2010940	hsa-miR-4653-5p	CLIP-seq
MIRT1048163	hsa-miR-4665-5p	CLIP-seq
MIRT2546390	hsa-miR-4690-5p	CLIP-seq
MIRT1048168	hsa-miR-4698	CLIP-seq
MIRT1048170	hsa-miR-4714-3p	CLIP-seq
MIRT1048174	hsa-miR-4723-5p	CLIP-seq
MIRT1048176	hsa-miR-4731-5p	CLIP-seq
MIRT2243154	hsa-miR-4761-5p	CLIP-seq
MIRT1048180	hsa-miR-4768-3p	CLIP-seq
MIRT1048183	hsa-miR-4803	CLIP-seq
MIRT2243160	hsa-miR-501-3p	CLIP-seq
MIRT2243161	hsa-miR-502-3p	CLIP-seq
MIRT1048188	hsa-miR-505	CLIP-seq
MIRT1048190	hsa-miR-512-3p	CLIP-seq
MIRT1048191	hsa-miR-543	CLIP-seq
MIRT1048201	hsa-miR-589	CLIP-seq
MIRT2546391	hsa-miR-599	CLIP-seq
MIRT755692	hsa-miR-603	CLIP-seq
MIRT1048204	hsa-miR-625	CLIP-seq
MIRT1048207	hsa-miR-637	CLIP-seq
MIRT2546392	hsa-miR-655	CLIP-seq
MIRT2546393	hsa-miR-662	CLIP-seq
MIRT2010957	hsa-miR-769-5p	CLIP-seq
MIRT1048216	hsa-miR-802	CLIP-seq

Transcription factors

Show/Hide all(1)

Transcription factor	Regulation	Reference
SREBF1	Unknown	14747281

Show/Hide all(40)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001666	Process	Response to hypoxia	IEA
GO:0001678	Process	Cellular glucose homeostasis	IBA	21873635
GO:0002931	Process	Response to ischemia	IEA
GO:0004340	Function	Glucokinase activity	IBA	21873635
GO:0004340	Function	Glucokinase activity	IDA	29298880
GO:0004396	Function	Hexokinase activity	IDA	26985301
GO:0005515	Function	Protein binding	IPI	16189514, 23185017, 25416956, 28054552
GO:0005524	Function	ATP binding	IEA
GO:0005536	Function	Glucose binding	IEA
GO:0005739	Component	Mitochondrion	IBA	21873635
GO:0005739	Component	Mitochondrion	IDA
GO:0005741	Component	Mitochondrial outer membrane	IDA	18350175
GO:0005813	Component	Centrosome	IDA
GO:0005829	Component	Cytosol	IBA	21873635
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IEA
GO:0006002	Process	Fructose 6-phosphate metabolic process	ISS
GO:0006096	Process	Glycolytic process	IBA	21873635
GO:0006096	Process	Glycolytic process	TAS	23962723
GO:0007595	Process	Lactation	IEA
GO:0008637	Process	Apoptotic mitochondrial changes	IDA	18350175
GO:0008865	Function	Fructokinase activity	IBA	21873635
GO:0008865	Function	Fructokinase activity	ISS
GO:0016020	Component	Membrane	HDA	19946888
GO:0016529	Component	Sarcoplasmic reticulum	IEA
GO:0019158	Function	Mannokinase activity	IBA	21873635
GO:0035795	Process	Negative regulation of mitochondrial membrane permeability	IEA
GO:0043231	Component	Intracellular membrane-bounded organelle	IDA
GO:0045766	Process	Positive regulation of angiogenesis	IMP	25801897
GO:0046324	Process	Regulation of glucose import	IEA
GO:0046835	Process	Carbohydrate phosphorylation	IEA
GO:0051156	Process	Glucose 6-phosphate metabolic process	IBA	21873635
GO:0051156	Process	Glucose 6-phosphate metabolic process	IDA	29298880
GO:0061621	Process	Canonical glycolysis	TAS
GO:0072655	Process	Establishment of protein localization to mitochondrion	IMP	23962723
GO:0072656	Process	Maintenance of protein location in mitochondrion	IMP	23962723
GO:1904925	Process	Positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization	IMP	23962723
GO:1990830	Process	Cellular response to leukemia inhibitory factor	IEA
GO:2000378	Process	Negative regulation of reactive oxygen species metabolic process	IEA

MIM	HGNC	e!Ensembl
601125	4923	ENSG00000159399

Protein

UniProt ID

P52789

Protein name

Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) (Hexokinase-B) (Muscle form hexokinase)

Protein function

Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively) (PubMed:23185017, PubMed:26985301, PubMed:29298880). Mediates the initial step of g

PDB

2NZT , 5HEX , 5HFU , 5HG1

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00349	Hexokinase_1	21 → 219	Hexokinase	Domain
PF03727	Hexokinase_2	225 → 459	Hexokinase	Domain
PF00349	Hexokinase_1	469 → 667	Hexokinase	Domain
PF03727	Hexokinase_2	673 → 907	Hexokinase	Domain

Sequence

MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAA
VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMR
GSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGV
EGRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYME
EMRHIDMVEGDEGRMCINMEWGAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGM
YMGELVRLILVKMAKEELLFGGKLSPELLNTGRFETKDISDIEGEKDGIRKAREVLMRLG
LDPTQEDCVATHRICQIVSTRSASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKH
PHFAKRLHKTVRRLVPGCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEHLQLS
HDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV
LLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGF
TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG
TMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDD
FRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG
IFETKFLSQIESDCLALLQVRAILQHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA
VVDRIRENRGLDALKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFLQSEDGSGKG
AALITAVACRIREAGQR

Sequence length

917

Interactions

View interactions

	KEGG		Reactome
	Glycolysis / Gluconeogenesis Fructose and mannose metabolism Galactose metabolism Starch and sucrose metabolism Amino sugar and nucleotide sugar metabolism Neomycin, kanamycin and gentamicin biosynthesis Metabolic pathways Carbon metabolism Biosynthesis of nucleotide sugars HIF-1 signaling pathway Insulin signaling pathway Type II diabetes mellitus Carbohydrate digestion and absorption Shigellosis Central carbon metabolism in cancer		Glycolysis

Associated diseases

Show/Hide Causal Diseases (3)

Causal
Disease name	Disease term	dbSNP ID	References
Lung adenocarcinoma	Adenocarcinoma of lung (disorder)	rs28934576, rs121913530, rs397516975, rs587776805, rs121913469, rs121913364, rs121913351, rs121913366, rs397516896, rs397516977, rs397516981, rs397517127, rs121913344, rs727504233, rs121913370, rs760043106, rs1057519788, rs1131692238, rs1131692237, rs1554350382	27602772
Obesity	Obesity	rs34911341, rs74315349, rs1474810899, rs2282440, rs2491132, rs121918111, rs796065034, rs753856820, rs796065035, rs121918112, rs104894023, rs137852821, rs1580764441, rs137852822, rs137852823, rs137852824, rs13447324, rs121913562, rs121913564, rs74315393, rs121913556, rs2989924, rs193922650, rs193922685, rs193922687, rs751160202, rs1421085, rs747681609, rs1553400259, rs13447339, rs370479598, rs1554394014, rs1553174844, rs756232889, rs369841551, rs1557670950, rs1571321748, rs148538980, rs1572820988, rs1591461970, rs1419374563, rs745921568, rs144159890, rs1570714352, rs779783209, rs1573250294, rs1573254045, rs1580744791, rs1580746829, rs6548238, rs7138803, rs7754840	20882379
Schizophrenia	Schizophrenia	rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313	21926974

Show/Hide Unknown Diseases (1)

Unknown
Disease name	Disease term	dbSNP ID	References
Myocardial ischemia	Myocardial Ischemia		16214533

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