Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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30845 |
Gene nameGene Name - the full gene name approved by the HGNC.
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EH domain containing 3 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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EHD3 |
SynonymsGene synonyms aliases
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PAST3 |
ChromosomeChromosome number
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2 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2p23.1 |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
|
UniProt ID |
Q9NZN3 |
Protein name |
EH domain-containing protein 3 (PAST homolog 3) |
Protein function |
ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (PubMed:25686250). In vitro causes tubulation of endocytic membranes (PubMed:24019528). Binding to phosphatidic acid induces its membrane tubu |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF16880 |
EHD_N |
24 → 56 |
N-terminal EH-domain containing protein |
Family |
PF00350 |
Dynamin_N |
61 → 221 |
Dynamin family |
Domain |
PF18150 |
DUF5600 |
288 → 394 |
Domain of unknown function (DUF5600) |
Domain |
PF12763 |
EF-hand_4 |
439 → 535 |
Cytoskeletal-regulatory complex EF hand |
Family |
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Sequence |
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Sequence length |
535 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Leukemia |
Leukemia, Myelocytic, Acute, Acute Myeloid Leukemia (AML-M2) |
rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297, rs11978267, rs4132601 |
17330099 |
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