UQCR10 (ubiquinol-cytochrome c reductase, complex III subunit X)

Gene

• Entrez ID: 29796
• Gene name: Ubiquinol-cytochrome c reductase, complex III subunit X
• Gene symbol: UQCR10
• Synonyms: HSPC051, HSPC119, HSPC151, QCR9, UCCR7.2, UCRC
• Chromosome: 22
• Chromosome location: 22q12.2
• Summary: UCRC is a subunit of mitochondrial complex III (ubiquinol-cytochrome c reductase; EC 1.10.2.2), which forms the middle segment of the respiratory chain of the inner mitochondrial membrane (Schagger et al., 1995 [PubMed 8592474]).[supplied by OMIM, Mar 200

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT048647	hsa-miR-99a-5p	CLASH	23622248
MIRT046897	hsa-miR-221-3p	CLASH	23622248
MIRT042747	hsa-miR-339-5p	CLASH	23622248
MIRT495635	hsa-miR-3667-5p	PAR-CLIP	22291592
MIRT495634	hsa-miR-548ao-3p	PAR-CLIP	22291592
MIRT495633	hsa-miR-5195-5p	PAR-CLIP	22291592
MIRT495632	hsa-miR-4717-5p	PAR-CLIP	22291592
MIRT495631	hsa-miR-15a-3p	PAR-CLIP	22291592
MIRT495630	hsa-miR-6846-3p	PAR-CLIP	22291592
MIRT495629	hsa-miR-5704	PAR-CLIP	22291592
MIRT495635	hsa-miR-3667-5p	PAR-CLIP	22291592
MIRT495634	hsa-miR-548ao-3p	PAR-CLIP	22291592
MIRT495633	hsa-miR-5195-5p	PAR-CLIP	22291592
MIRT495632	hsa-miR-4717-5p	PAR-CLIP	22291592
MIRT495631	hsa-miR-15a-3p	PAR-CLIP	22291592
MIRT495630	hsa-miR-6846-3p	PAR-CLIP	22291592
MIRT495629	hsa-miR-5704	PAR-CLIP	22291592
MIRT495635	hsa-miR-3667-5p	PAR-CLIP	22291592
MIRT495634	hsa-miR-548ao-3p	PAR-CLIP	22291592
MIRT495633	hsa-miR-5195-5p	PAR-CLIP	22291592
MIRT495632	hsa-miR-4717-5p	PAR-CLIP	22291592
MIRT495631	hsa-miR-15a-3p	PAR-CLIP	22291592
MIRT495630	hsa-miR-6846-3p	PAR-CLIP	22291592
MIRT495629	hsa-miR-5704	PAR-CLIP	22291592
MIRT495635	hsa-miR-3667-5p	PAR-CLIP	22291592
MIRT495634	hsa-miR-548ao-3p	PAR-CLIP	22291592
MIRT495633	hsa-miR-5195-5p	PAR-CLIP	22291592
MIRT495632	hsa-miR-4717-5p	PAR-CLIP	22291592
MIRT495631	hsa-miR-15a-3p	PAR-CLIP	22291592
MIRT495630	hsa-miR-6846-3p	PAR-CLIP	22291592
MIRT495629	hsa-miR-5704	PAR-CLIP	22291592
MIRT1476510	hsa-miR-1200	CLIP-seq
MIRT1476511	hsa-miR-1261	CLIP-seq
MIRT1476512	hsa-miR-1915	CLIP-seq
MIRT1476513	hsa-miR-2052	CLIP-seq
MIRT1476514	hsa-miR-23a	CLIP-seq
MIRT1476515	hsa-miR-23b	CLIP-seq
MIRT1476516	hsa-miR-23c	CLIP-seq
MIRT1476517	hsa-miR-2467-3p	CLIP-seq
MIRT1476518	hsa-miR-3074-5p	CLIP-seq
MIRT1476519	hsa-miR-3148	CLIP-seq
MIRT1476520	hsa-miR-3158-3p	CLIP-seq
MIRT1476521	hsa-miR-3545-5p	CLIP-seq
MIRT1476522	hsa-miR-3616-5p	CLIP-seq
MIRT1476523	hsa-miR-3647-5p	CLIP-seq
MIRT1476524	hsa-miR-3678-3p	CLIP-seq
MIRT1476525	hsa-miR-3688-3p	CLIP-seq
MIRT1476526	hsa-miR-371b-5p	CLIP-seq
MIRT1476527	hsa-miR-4324	CLIP-seq
MIRT1476528	hsa-miR-4670-3p	CLIP-seq
MIRT1476529	hsa-miR-4698	CLIP-seq
MIRT1476530	hsa-miR-4721	CLIP-seq
MIRT1476531	hsa-miR-4729	CLIP-seq
MIRT1476532	hsa-miR-4786-3p	CLIP-seq
MIRT1476533	hsa-miR-4795-5p	CLIP-seq
MIRT1476534	hsa-miR-544b	CLIP-seq
MIRT1476535	hsa-miR-569	CLIP-seq
MIRT1476536	hsa-miR-573	CLIP-seq
MIRT1476537	hsa-miR-578	CLIP-seq
MIRT1476538	hsa-miR-671-5p	CLIP-seq
MIRT1476539	hsa-miR-888	CLIP-seq
MIRT1476540	hsa-miR-1183	CLIP-seq
MIRT1476510	hsa-miR-1200	CLIP-seq
MIRT1476541	hsa-miR-1276	CLIP-seq
MIRT1476542	hsa-miR-129-5p	CLIP-seq
MIRT1476543	hsa-miR-147	CLIP-seq
MIRT1476513	hsa-miR-2052	CLIP-seq
MIRT1476514	hsa-miR-23a	CLIP-seq
MIRT1476515	hsa-miR-23b	CLIP-seq
MIRT1476516	hsa-miR-23c	CLIP-seq
MIRT1476544	hsa-miR-298	CLIP-seq
MIRT1476518	hsa-miR-3074-5p	CLIP-seq
MIRT1476545	hsa-miR-3136-3p	CLIP-seq
MIRT1476546	hsa-miR-3911	CLIP-seq
MIRT1476547	hsa-miR-4311	CLIP-seq
MIRT1476527	hsa-miR-4324	CLIP-seq
MIRT1476548	hsa-miR-4477a	CLIP-seq
MIRT1476549	hsa-miR-450b-5p	CLIP-seq
MIRT1476550	hsa-miR-4693-5p	CLIP-seq
MIRT1476551	hsa-miR-4712-3p	CLIP-seq
MIRT1476552	hsa-miR-4728-3p	CLIP-seq
MIRT1476531	hsa-miR-4729	CLIP-seq
MIRT1476553	hsa-miR-4742-3p	CLIP-seq
MIRT1476554	hsa-miR-507	CLIP-seq
MIRT1476534	hsa-miR-544b	CLIP-seq
MIRT1476555	hsa-miR-548ag	CLIP-seq
MIRT1476556	hsa-miR-548ai	CLIP-seq
MIRT1476557	hsa-miR-557	CLIP-seq
MIRT1476558	hsa-miR-583	CLIP-seq
MIRT1476559	hsa-miR-628-5p	CLIP-seq
MIRT1476560	hsa-miR-644	CLIP-seq
MIRT1476561	hsa-miR-663b	CLIP-seq
MIRT1476562	hsa-miR-922	CLIP-seq
MIRT1476510	hsa-miR-1200	CLIP-seq
MIRT1476513	hsa-miR-2052	CLIP-seq
MIRT1476514	hsa-miR-23a	CLIP-seq
MIRT1476515	hsa-miR-23b	CLIP-seq
MIRT1476516	hsa-miR-23c	CLIP-seq
MIRT1476518	hsa-miR-3074-5p	CLIP-seq
MIRT1476531	hsa-miR-4729	CLIP-seq
MIRT1476514	hsa-miR-23a	CLIP-seq
MIRT1476515	hsa-miR-23b	CLIP-seq
MIRT1476516	hsa-miR-23c	CLIP-seq
MIRT1476518	hsa-miR-3074-5p	CLIP-seq
MIRT1476531	hsa-miR-4729	CLIP-seq
MIRT1476510	hsa-miR-1200	CLIP-seq
MIRT1476541	hsa-miR-1276	CLIP-seq
MIRT2143563	hsa-miR-1285	CLIP-seq
MIRT2143564	hsa-miR-1293	CLIP-seq
MIRT2143565	hsa-miR-1911	CLIP-seq
MIRT1476514	hsa-miR-23a	CLIP-seq
MIRT1476515	hsa-miR-23b	CLIP-seq
MIRT1476516	hsa-miR-23c	CLIP-seq
MIRT2143566	hsa-miR-2467-5p	CLIP-seq
MIRT1476544	hsa-miR-298	CLIP-seq
MIRT1476518	hsa-miR-3074-5p	CLIP-seq
MIRT2143567	hsa-miR-3187-5p	CLIP-seq
MIRT2143568	hsa-miR-3188	CLIP-seq
MIRT2143569	hsa-miR-3200-3p	CLIP-seq
MIRT2143570	hsa-miR-323-5p	CLIP-seq
MIRT2143571	hsa-miR-326	CLIP-seq
MIRT2143572	hsa-miR-330-5p	CLIP-seq
MIRT2143573	hsa-miR-3661	CLIP-seq
MIRT2143574	hsa-miR-378g	CLIP-seq
MIRT2143575	hsa-miR-3975	CLIP-seq
MIRT2143576	hsa-miR-4267	CLIP-seq
MIRT1476547	hsa-miR-4311	CLIP-seq
MIRT1476527	hsa-miR-4324	CLIP-seq
MIRT2143577	hsa-miR-4483	CLIP-seq
MIRT2143578	hsa-miR-4486	CLIP-seq
MIRT2143579	hsa-miR-4535	CLIP-seq
MIRT2143580	hsa-miR-4649-3p	CLIP-seq
MIRT2143581	hsa-miR-4709-3p	CLIP-seq
MIRT1476552	hsa-miR-4728-3p	CLIP-seq
MIRT1476531	hsa-miR-4729	CLIP-seq
MIRT2143582	hsa-miR-4731-5p	CLIP-seq
MIRT2143583	hsa-miR-4790-3p	CLIP-seq
MIRT2143584	hsa-miR-4800-5p	CLIP-seq
MIRT2143585	hsa-miR-485-5p	CLIP-seq
MIRT2143586	hsa-miR-492	CLIP-seq
MIRT2143587	hsa-miR-498	CLIP-seq
MIRT2143588	hsa-miR-513c	CLIP-seq
MIRT2143589	hsa-miR-514b-5p	CLIP-seq
MIRT1476534	hsa-miR-544b	CLIP-seq
MIRT1476555	hsa-miR-548ag	CLIP-seq
MIRT1476556	hsa-miR-548ai	CLIP-seq
MIRT1476537	hsa-miR-578	CLIP-seq
MIRT1476558	hsa-miR-583	CLIP-seq
MIRT2143590	hsa-miR-612	CLIP-seq
MIRT1476559	hsa-miR-628-5p	CLIP-seq
MIRT2143591	hsa-miR-631	CLIP-seq
MIRT2143592	hsa-miR-766	CLIP-seq
MIRT2143593	hsa-miR-876-3p	CLIP-seq
MIRT1476562	hsa-miR-922	CLIP-seq
MIRT1476510	hsa-miR-1200	CLIP-seq
MIRT1476541	hsa-miR-1276	CLIP-seq
MIRT2143563	hsa-miR-1285	CLIP-seq
MIRT2143564	hsa-miR-1293	CLIP-seq
MIRT2143565	hsa-miR-1911	CLIP-seq
MIRT1476513	hsa-miR-2052	CLIP-seq
MIRT1476514	hsa-miR-23a	CLIP-seq
MIRT1476515	hsa-miR-23b	CLIP-seq
MIRT1476516	hsa-miR-23c	CLIP-seq
MIRT2143566	hsa-miR-2467-5p	CLIP-seq
MIRT1476544	hsa-miR-298	CLIP-seq
MIRT1476518	hsa-miR-3074-5p	CLIP-seq
MIRT2143567	hsa-miR-3187-5p	CLIP-seq
MIRT2143568	hsa-miR-3188	CLIP-seq
MIRT2143569	hsa-miR-3200-3p	CLIP-seq
MIRT2143570	hsa-miR-323-5p	CLIP-seq
MIRT2143571	hsa-miR-326	CLIP-seq
MIRT2143572	hsa-miR-330-5p	CLIP-seq
MIRT2143573	hsa-miR-3661	CLIP-seq
MIRT2143574	hsa-miR-378g	CLIP-seq
MIRT2143575	hsa-miR-3975	CLIP-seq
MIRT2143576	hsa-miR-4267	CLIP-seq
MIRT1476547	hsa-miR-4311	CLIP-seq
MIRT1476527	hsa-miR-4324	CLIP-seq
MIRT2363804	hsa-miR-4470	CLIP-seq
MIRT2143577	hsa-miR-4483	CLIP-seq
MIRT2143578	hsa-miR-4486	CLIP-seq
MIRT2143579	hsa-miR-4535	CLIP-seq
MIRT2143580	hsa-miR-4649-3p	CLIP-seq
MIRT2143581	hsa-miR-4709-3p	CLIP-seq
MIRT1476552	hsa-miR-4728-3p	CLIP-seq
MIRT1476531	hsa-miR-4729	CLIP-seq
MIRT2143582	hsa-miR-4731-5p	CLIP-seq
MIRT2143583	hsa-miR-4790-3p	CLIP-seq
MIRT2143584	hsa-miR-4800-5p	CLIP-seq
MIRT2143585	hsa-miR-485-5p	CLIP-seq
MIRT2143586	hsa-miR-492	CLIP-seq
MIRT2143587	hsa-miR-498	CLIP-seq
MIRT2143588	hsa-miR-513c	CLIP-seq
MIRT2143589	hsa-miR-514b-5p	CLIP-seq
MIRT1476534	hsa-miR-544b	CLIP-seq
MIRT1476555	hsa-miR-548ag	CLIP-seq
MIRT1476556	hsa-miR-548ai	CLIP-seq
MIRT1476537	hsa-miR-578	CLIP-seq
MIRT1476558	hsa-miR-583	CLIP-seq
MIRT2143590	hsa-miR-612	CLIP-seq
MIRT1476559	hsa-miR-628-5p	CLIP-seq
MIRT2143591	hsa-miR-631	CLIP-seq
MIRT2143592	hsa-miR-766	CLIP-seq
MIRT2143593	hsa-miR-876-3p	CLIP-seq
MIRT1476562	hsa-miR-922	CLIP-seq
MIRT1476510	hsa-miR-1200	CLIP-seq
MIRT1476541	hsa-miR-1276	CLIP-seq
MIRT2143563	hsa-miR-1285	CLIP-seq
MIRT2143565	hsa-miR-1911	CLIP-seq
MIRT1476513	hsa-miR-2052	CLIP-seq
MIRT1476514	hsa-miR-23a	CLIP-seq
MIRT1476515	hsa-miR-23b	CLIP-seq
MIRT1476516	hsa-miR-23c	CLIP-seq
MIRT2143566	hsa-miR-2467-5p	CLIP-seq
MIRT1476544	hsa-miR-298	CLIP-seq
MIRT1476518	hsa-miR-3074-5p	CLIP-seq
MIRT2143567	hsa-miR-3187-5p	CLIP-seq
MIRT2143568	hsa-miR-3188	CLIP-seq
MIRT2143569	hsa-miR-3200-3p	CLIP-seq
MIRT2143570	hsa-miR-323-5p	CLIP-seq
MIRT2143571	hsa-miR-326	CLIP-seq
MIRT2657546	hsa-miR-330-3p	CLIP-seq
MIRT2143572	hsa-miR-330-5p	CLIP-seq
MIRT2657547	hsa-miR-3668	CLIP-seq
MIRT2143574	hsa-miR-378g	CLIP-seq
MIRT2657548	hsa-miR-3927	CLIP-seq
MIRT2143575	hsa-miR-3975	CLIP-seq
MIRT2143576	hsa-miR-4267	CLIP-seq
MIRT1476547	hsa-miR-4311	CLIP-seq
MIRT1476527	hsa-miR-4324	CLIP-seq
MIRT2657549	hsa-miR-4424	CLIP-seq
MIRT2657550	hsa-miR-4451	CLIP-seq
MIRT2143578	hsa-miR-4486	CLIP-seq
MIRT2143580	hsa-miR-4649-3p	CLIP-seq
MIRT2657551	hsa-miR-4699-5p	CLIP-seq
MIRT2143581	hsa-miR-4709-3p	CLIP-seq
MIRT1476552	hsa-miR-4728-3p	CLIP-seq
MIRT1476531	hsa-miR-4729	CLIP-seq
MIRT2657552	hsa-miR-4772-5p	CLIP-seq
MIRT2143583	hsa-miR-4790-3p	CLIP-seq
MIRT2143585	hsa-miR-485-5p	CLIP-seq
MIRT2657553	hsa-miR-495	CLIP-seq
MIRT2143587	hsa-miR-498	CLIP-seq
MIRT2143588	hsa-miR-513c	CLIP-seq
MIRT2143589	hsa-miR-514b-5p	CLIP-seq
MIRT1476534	hsa-miR-544b	CLIP-seq
MIRT1476555	hsa-miR-548ag	CLIP-seq
MIRT1476556	hsa-miR-548ai	CLIP-seq
MIRT1476537	hsa-miR-578	CLIP-seq
MIRT1476558	hsa-miR-583	CLIP-seq
MIRT2143590	hsa-miR-612	CLIP-seq
MIRT1476559	hsa-miR-628-5p	CLIP-seq
MIRT2143592	hsa-miR-766	CLIP-seq
MIRT2143593	hsa-miR-876-3p	CLIP-seq
MIRT1476562	hsa-miR-922	CLIP-seq
MIRT1476510	hsa-miR-1200	CLIP-seq
MIRT2694782	hsa-miR-1237	CLIP-seq
MIRT2694783	hsa-miR-1248	CLIP-seq
MIRT1476541	hsa-miR-1276	CLIP-seq
MIRT2143563	hsa-miR-1285	CLIP-seq
MIRT2143564	hsa-miR-1293	CLIP-seq
MIRT2143565	hsa-miR-1911	CLIP-seq
MIRT1476513	hsa-miR-2052	CLIP-seq
MIRT1476514	hsa-miR-23a	CLIP-seq
MIRT1476515	hsa-miR-23b	CLIP-seq
MIRT1476516	hsa-miR-23c	CLIP-seq
MIRT2143566	hsa-miR-2467-5p	CLIP-seq
MIRT1476544	hsa-miR-298	CLIP-seq
MIRT1476518	hsa-miR-3074-5p	CLIP-seq
MIRT2143567	hsa-miR-3187-5p	CLIP-seq
MIRT2143568	hsa-miR-3188	CLIP-seq
MIRT2143569	hsa-miR-3200-3p	CLIP-seq
MIRT2143570	hsa-miR-323-5p	CLIP-seq
MIRT2143571	hsa-miR-326	CLIP-seq
MIRT2657546	hsa-miR-330-3p	CLIP-seq
MIRT2143572	hsa-miR-330-5p	CLIP-seq
MIRT2143573	hsa-miR-3661	CLIP-seq
MIRT2657547	hsa-miR-3668	CLIP-seq
MIRT2143574	hsa-miR-378g	CLIP-seq
MIRT2657548	hsa-miR-3927	CLIP-seq
MIRT2143575	hsa-miR-3975	CLIP-seq
MIRT2143576	hsa-miR-4267	CLIP-seq
MIRT1476547	hsa-miR-4311	CLIP-seq
MIRT1476527	hsa-miR-4324	CLIP-seq
MIRT2657549	hsa-miR-4424	CLIP-seq
MIRT2657550	hsa-miR-4451	CLIP-seq
MIRT2363804	hsa-miR-4470	CLIP-seq
MIRT2143577	hsa-miR-4483	CLIP-seq
MIRT2143578	hsa-miR-4486	CLIP-seq
MIRT2143579	hsa-miR-4535	CLIP-seq
MIRT2143580	hsa-miR-4649-3p	CLIP-seq
MIRT2657551	hsa-miR-4699-5p	CLIP-seq
MIRT2143581	hsa-miR-4709-3p	CLIP-seq
MIRT1476552	hsa-miR-4728-3p	CLIP-seq
MIRT1476531	hsa-miR-4729	CLIP-seq
MIRT2143582	hsa-miR-4731-5p	CLIP-seq
MIRT2657552	hsa-miR-4772-5p	CLIP-seq
MIRT2143583	hsa-miR-4790-3p	CLIP-seq
MIRT2143584	hsa-miR-4800-5p	CLIP-seq
MIRT2143585	hsa-miR-485-5p	CLIP-seq
MIRT2143586	hsa-miR-492	CLIP-seq
MIRT2657553	hsa-miR-495	CLIP-seq
MIRT2143587	hsa-miR-498	CLIP-seq
MIRT2143588	hsa-miR-513c	CLIP-seq
MIRT2143589	hsa-miR-514b-5p	CLIP-seq
MIRT1476534	hsa-miR-544b	CLIP-seq
MIRT1476555	hsa-miR-548ag	CLIP-seq
MIRT1476556	hsa-miR-548ai	CLIP-seq
MIRT1476537	hsa-miR-578	CLIP-seq
MIRT1476558	hsa-miR-583	CLIP-seq
MIRT2143590	hsa-miR-612	CLIP-seq
MIRT1476559	hsa-miR-628-5p	CLIP-seq
MIRT2143591	hsa-miR-631	CLIP-seq
MIRT2143592	hsa-miR-766	CLIP-seq
MIRT2143593	hsa-miR-876-3p	CLIP-seq
MIRT1476562	hsa-miR-922	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005743	Component	Mitochondrial inner membrane	TAS
GO:0005750	Component	Mitochondrial respiratory chain complex III	IBA	21873635
GO:0006122	Process	Mitochondrial electron transport, ubiquinol to cytochrome c	IBA	21873635
GO:0006122	Process	Mitochondrial electron transport, ubiquinol to cytochrome c	NAS	8592474
GO:0006122	Process	Mitochondrial electron transport, ubiquinol to cytochrome c	TAS
GO:0008121	Function	Ubiquinol-cytochrome-c reductase activity	NAS	8592474
GO:0009060	Process	Aerobic respiration	IBA	21873635
GO:0016021	Component	Integral component of membrane	IEA

Other IDs

• MIM: 610843
• HGNC: 30863
• e!Ensembl: ENSG00000184076

Protein

• UniProt ID: Q9UDW1
• Protein name: Cytochrome b-c1 complex subunit 9 (Complex III subunit 9) (Complex III subunit X) (Cytochrome c1 non-heme 7 kDa protein) (Ubiquinol-cytochrome c reductase complex 7.2 kDa protein)
• Protein function: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complex
• PDB: 5XTE, 5XTH, 5XTI
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF05365	UCR_UQCRX_QCR9	8 → 60	Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like	Family

• Sequence:

  MAAATLTSKLYSLLFRRTSTFALTIIVGVMFFERAFDQGADAIYDHINEGKLWKHIKHKY
  ENK

• Sequence length: 63

Pathways

KEGG:

Oxidative phosphorylation
Metabolic pathways
Cardiac muscle contraction
Thermogenesis
Non-alcoholic fatty liver disease
Alzheimer disease
Parkinson disease
Amyotrophic lateral sclerosis
Huntington disease
Prion disease
Pathways of neurodegeneration - multiple diseases
Chemical carcinogenesis - reactive oxygen species
Diabetic cardiomyopathy

Reactome:

Respiratory electron transport

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Psoriasis	Psoriasis	rs281875215, rs587777763, rs281875213, rs281875212	26974007

Unknown
Disease name	Disease term	dbSNP ID	References
Ankylosing spondylitis	Ankylosing spondylitis		26974007
Cholangitis	Cholangitis, Sclerosing		26974007
Crohn disease	Crohn Disease	rs2066847, rs2066844, rs886052047, rs5743265, rs111608429, rs104895438	26974007
Ulcerative colitis	Ulcerative Colitis		26974007