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DNAJC15 (DnaJ heat shock protein family (Hsp40) member C15)

Gene

29103

DnaJ heat shock protein family (Hsp40) member C15

DNAJC15

DNAJD1, HSD18, MCJ

13q14.11

Show/Hide all(258)

miRTarBase ID	miRNA	Experiments	Reference
MIRT031683	hsa-miR-16-5p	Proteomics	18668040
MIRT606986	hsa-miR-6867-5p	HITS-CLIP	23313552
MIRT688452	hsa-miR-450b-5p	HITS-CLIP	23313552
MIRT688451	hsa-miR-507	HITS-CLIP	23313552
MIRT688450	hsa-miR-557	HITS-CLIP	23313552
MIRT688449	hsa-miR-3680-3p	HITS-CLIP	23313552
MIRT688448	hsa-miR-129-5p	HITS-CLIP	23313552
MIRT606983	hsa-miR-574-5p	HITS-CLIP	23313552
MIRT606993	hsa-miR-4716-3p	HITS-CLIP	24906430
MIRT606992	hsa-miR-6794-5p	HITS-CLIP	24906430
MIRT606991	hsa-miR-6805-5p	HITS-CLIP	24906430
MIRT606990	hsa-miR-6732-5p	HITS-CLIP	24906430
MIRT606989	hsa-miR-625-5p	HITS-CLIP	24906430
MIRT606988	hsa-miR-6795-5p	HITS-CLIP	24906430
MIRT606987	hsa-miR-6887-5p	HITS-CLIP	24906430
MIRT606986	hsa-miR-6867-5p	HITS-CLIP	24906430
MIRT606985	hsa-miR-4278	HITS-CLIP	24906430
MIRT606984	hsa-miR-135b-3p	HITS-CLIP	24906430
MIRT606983	hsa-miR-574-5p	HITS-CLIP	24906430
MIRT454869	hsa-miR-5580-3p	PAR-CLIP	21572407
MIRT454868	hsa-miR-4464	PAR-CLIP	21572407
MIRT454867	hsa-miR-4748	PAR-CLIP	21572407
MIRT524070	hsa-miR-5589-3p	PAR-CLIP	21572407
MIRT454866	hsa-miR-3665	PAR-CLIP	21572407
MIRT454865	hsa-miR-657	PAR-CLIP	21572407
MIRT454864	hsa-miR-5087	PAR-CLIP	21572407
MIRT454863	hsa-miR-8068	PAR-CLIP	21572407
MIRT454869	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT454868	hsa-miR-4464	PAR-CLIP	23446348
MIRT454867	hsa-miR-4748	PAR-CLIP	23446348
MIRT524070	hsa-miR-5589-3p	PAR-CLIP	23446348
MIRT454866	hsa-miR-3665	PAR-CLIP	23446348
MIRT454865	hsa-miR-657	PAR-CLIP	23446348
MIRT454864	hsa-miR-5087	PAR-CLIP	23446348
MIRT454863	hsa-miR-8068	PAR-CLIP	23446348
MIRT454869	hsa-miR-5580-3p	PAR-CLIP	23592263
MIRT454868	hsa-miR-4464	PAR-CLIP	23592263
MIRT454867	hsa-miR-4748	PAR-CLIP	23592263
MIRT454866	hsa-miR-3665	PAR-CLIP	23592263
MIRT454865	hsa-miR-657	PAR-CLIP	23592263
MIRT454864	hsa-miR-5087	PAR-CLIP	23592263
MIRT454863	hsa-miR-8068	PAR-CLIP	23592263
MIRT688448	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT688448	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT606984	hsa-miR-135b-3p	HITS-CLIP	27418678
MIRT688449	hsa-miR-3680-3p	HITS-CLIP	27418678
MIRT688449	hsa-miR-3680-3p	HITS-CLIP	27418678
MIRT606985	hsa-miR-4278	HITS-CLIP	27418678
MIRT688452	hsa-miR-450b-5p	HITS-CLIP	27418678
MIRT688452	hsa-miR-450b-5p	HITS-CLIP	27418678
MIRT606993	hsa-miR-4716-3p	HITS-CLIP	27418678
MIRT688451	hsa-miR-507	HITS-CLIP	27418678
MIRT688451	hsa-miR-507	HITS-CLIP	27418678
MIRT688450	hsa-miR-557	HITS-CLIP	27418678
MIRT688450	hsa-miR-557	HITS-CLIP	27418678
MIRT606983	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT606983	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT606990	hsa-miR-6732-5p	HITS-CLIP	27418678
MIRT606992	hsa-miR-6794-5p	HITS-CLIP	27418678
MIRT606991	hsa-miR-6805-5p	HITS-CLIP	27418678
MIRT606986	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT606986	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT606986	hsa-miR-6867-5p	HITS-CLIP	23313552
MIRT688452	hsa-miR-450b-5p	HITS-CLIP	23313552
MIRT688451	hsa-miR-507	HITS-CLIP	23313552
MIRT688450	hsa-miR-557	HITS-CLIP	23313552
MIRT688449	hsa-miR-3680-3p	HITS-CLIP	23313552
MIRT688448	hsa-miR-129-5p	HITS-CLIP	23313552
MIRT606983	hsa-miR-574-5p	HITS-CLIP	23313552
MIRT454869	hsa-miR-5580-3p	PAR-CLIP	21572407
MIRT454868	hsa-miR-4464	PAR-CLIP	21572407
MIRT454867	hsa-miR-4748	PAR-CLIP	21572407
MIRT524070	hsa-miR-5589-3p	PAR-CLIP	21572407
MIRT454866	hsa-miR-3665	PAR-CLIP	21572407
MIRT454865	hsa-miR-657	PAR-CLIP	21572407
MIRT454864	hsa-miR-5087	PAR-CLIP	21572407
MIRT454863	hsa-miR-8068	PAR-CLIP	21572407
MIRT454869	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT454868	hsa-miR-4464	PAR-CLIP	23446348
MIRT454867	hsa-miR-4748	PAR-CLIP	23446348
MIRT524070	hsa-miR-5589-3p	PAR-CLIP	23446348
MIRT454866	hsa-miR-3665	PAR-CLIP	23446348
MIRT454865	hsa-miR-657	PAR-CLIP	23446348
MIRT454864	hsa-miR-5087	PAR-CLIP	23446348
MIRT454863	hsa-miR-8068	PAR-CLIP	23446348
MIRT454869	hsa-miR-5580-3p	PAR-CLIP	23592263
MIRT454868	hsa-miR-4464	PAR-CLIP	23592263
MIRT454867	hsa-miR-4748	PAR-CLIP	23592263
MIRT454866	hsa-miR-3665	PAR-CLIP	23592263
MIRT454865	hsa-miR-657	PAR-CLIP	23592263
MIRT454864	hsa-miR-5087	PAR-CLIP	23592263
MIRT454863	hsa-miR-8068	PAR-CLIP	23592263
MIRT940707	hsa-miR-3935	CLIP-seq
MIRT940708	hsa-miR-411	CLIP-seq
MIRT940709	hsa-miR-4270	CLIP-seq
MIRT940710	hsa-miR-4441	CLIP-seq
MIRT940711	hsa-miR-577	CLIP-seq
MIRT1978192	hsa-miR-1229	CLIP-seq
MIRT1978193	hsa-miR-2117	CLIP-seq
MIRT1978194	hsa-miR-3673	CLIP-seq
MIRT1978195	hsa-miR-4273	CLIP-seq
MIRT1978196	hsa-miR-4719	CLIP-seq
MIRT1978197	hsa-miR-4768-5p	CLIP-seq
MIRT1978198	hsa-miR-625	CLIP-seq
MIRT2213714	hsa-miR-202	CLIP-seq
MIRT1978193	hsa-miR-2117	CLIP-seq
MIRT1978194	hsa-miR-3673	CLIP-seq
MIRT2213715	hsa-miR-3942-3p	CLIP-seq
MIRT1978195	hsa-miR-4273	CLIP-seq
MIRT1978197	hsa-miR-4768-5p	CLIP-seq
MIRT2213716	hsa-miR-513c	CLIP-seq
MIRT2213717	hsa-miR-514b-5p	CLIP-seq
MIRT2213718	hsa-miR-515-5p	CLIP-seq
MIRT2517557	hsa-miR-101	CLIP-seq
MIRT2517558	hsa-miR-106a	CLIP-seq
MIRT2517559	hsa-miR-106b	CLIP-seq
MIRT1978192	hsa-miR-1229	CLIP-seq
MIRT2517560	hsa-miR-1238	CLIP-seq
MIRT2517561	hsa-miR-1243	CLIP-seq
MIRT2517562	hsa-miR-1278	CLIP-seq
MIRT2517563	hsa-miR-1279	CLIP-seq
MIRT2517564	hsa-miR-132	CLIP-seq
MIRT2517565	hsa-miR-137	CLIP-seq
MIRT2517566	hsa-miR-141	CLIP-seq
MIRT2517567	hsa-miR-144	CLIP-seq
MIRT2517568	hsa-miR-17	CLIP-seq
MIRT2517569	hsa-miR-200a	CLIP-seq
MIRT2517570	hsa-miR-20a	CLIP-seq
MIRT2517571	hsa-miR-20b	CLIP-seq
MIRT1978193	hsa-miR-2117	CLIP-seq
MIRT2517572	hsa-miR-212	CLIP-seq
MIRT2517573	hsa-miR-3074-3p	CLIP-seq
MIRT2517574	hsa-miR-3121-5p	CLIP-seq
MIRT2517575	hsa-miR-3124-3p	CLIP-seq
MIRT2517576	hsa-miR-3200-5p	CLIP-seq
MIRT2517577	hsa-miR-320a	CLIP-seq
MIRT2517578	hsa-miR-320b	CLIP-seq
MIRT2517579	hsa-miR-320c	CLIP-seq
MIRT2517580	hsa-miR-320d	CLIP-seq
MIRT2517581	hsa-miR-3545-3p	CLIP-seq
MIRT2517582	hsa-miR-3609	CLIP-seq
MIRT2517583	hsa-miR-362-5p	CLIP-seq
MIRT2517584	hsa-miR-3654	CLIP-seq
MIRT2517585	hsa-miR-3667-3p	CLIP-seq
MIRT2517586	hsa-miR-3669	CLIP-seq
MIRT1978194	hsa-miR-3673	CLIP-seq
MIRT2517587	hsa-miR-3674	CLIP-seq
MIRT2517588	hsa-miR-383	CLIP-seq
MIRT940707	hsa-miR-3935	CLIP-seq
MIRT2517589	hsa-miR-3936	CLIP-seq
MIRT940708	hsa-miR-411	CLIP-seq
MIRT2517590	hsa-miR-4263	CLIP-seq
MIRT940709	hsa-miR-4270	CLIP-seq
MIRT1978195	hsa-miR-4273	CLIP-seq
MIRT2517591	hsa-miR-4330	CLIP-seq
MIRT2517592	hsa-miR-4427	CLIP-seq
MIRT2517593	hsa-miR-4429	CLIP-seq
MIRT2517594	hsa-miR-4437	CLIP-seq
MIRT940710	hsa-miR-4441	CLIP-seq
MIRT2517595	hsa-miR-4494	CLIP-seq
MIRT2517596	hsa-miR-4502	CLIP-seq
MIRT2517597	hsa-miR-4509	CLIP-seq
MIRT2517598	hsa-miR-4639-5p	CLIP-seq
MIRT2517599	hsa-miR-4659a-3p	CLIP-seq
MIRT2517600	hsa-miR-4659b-3p	CLIP-seq
MIRT2517601	hsa-miR-4666-3p	CLIP-seq
MIRT2517602	hsa-miR-4680-3p	CLIP-seq
MIRT2517603	hsa-miR-4714-3p	CLIP-seq
MIRT1978196	hsa-miR-4719	CLIP-seq
MIRT2517604	hsa-miR-4742-3p	CLIP-seq
MIRT2517605	hsa-miR-4744	CLIP-seq
MIRT2517606	hsa-miR-4760-3p	CLIP-seq
MIRT2517607	hsa-miR-4763-5p	CLIP-seq
MIRT1978197	hsa-miR-4768-5p	CLIP-seq
MIRT2517608	hsa-miR-4772-5p	CLIP-seq
MIRT2517609	hsa-miR-4777-3p	CLIP-seq
MIRT2517610	hsa-miR-4796-3p	CLIP-seq
MIRT2517611	hsa-miR-4799-5p	CLIP-seq
MIRT2517612	hsa-miR-499a-5p	CLIP-seq
MIRT2517613	hsa-miR-500b	CLIP-seq
MIRT2517614	hsa-miR-501-5p	CLIP-seq
MIRT2517615	hsa-miR-513a-5p	CLIP-seq
MIRT2517616	hsa-miR-519d	CLIP-seq
MIRT2517617	hsa-miR-539	CLIP-seq
MIRT2517618	hsa-miR-548ad	CLIP-seq
MIRT2517619	hsa-miR-548ah	CLIP-seq
MIRT2517620	hsa-miR-576-5p	CLIP-seq
MIRT940711	hsa-miR-577	CLIP-seq
MIRT2517621	hsa-miR-583	CLIP-seq
MIRT2517622	hsa-miR-7	CLIP-seq
MIRT2517623	hsa-miR-758	CLIP-seq
MIRT2517624	hsa-miR-769-5p	CLIP-seq
MIRT2517625	hsa-miR-93	CLIP-seq
MIRT2517626	hsa-miR-935	CLIP-seq
MIRT2517627	hsa-miR-942	CLIP-seq
MIRT2517557	hsa-miR-101	CLIP-seq
MIRT2517558	hsa-miR-106a	CLIP-seq
MIRT2517559	hsa-miR-106b	CLIP-seq
MIRT1978192	hsa-miR-1229	CLIP-seq
MIRT2517561	hsa-miR-1243	CLIP-seq
MIRT2517562	hsa-miR-1278	CLIP-seq
MIRT2517563	hsa-miR-1279	CLIP-seq
MIRT2517565	hsa-miR-137	CLIP-seq
MIRT2517566	hsa-miR-141	CLIP-seq
MIRT2517567	hsa-miR-144	CLIP-seq
MIRT2517568	hsa-miR-17	CLIP-seq
MIRT2517569	hsa-miR-200a	CLIP-seq
MIRT2517570	hsa-miR-20a	CLIP-seq
MIRT2517571	hsa-miR-20b	CLIP-seq
MIRT1978193	hsa-miR-2117	CLIP-seq
MIRT2517573	hsa-miR-3074-3p	CLIP-seq
MIRT2517574	hsa-miR-3121-5p	CLIP-seq
MIRT2517576	hsa-miR-3200-5p	CLIP-seq
MIRT2517577	hsa-miR-320a	CLIP-seq
MIRT2517578	hsa-miR-320b	CLIP-seq
MIRT2517579	hsa-miR-320c	CLIP-seq
MIRT2517580	hsa-miR-320d	CLIP-seq
MIRT2517581	hsa-miR-3545-3p	CLIP-seq
MIRT2517582	hsa-miR-3609	CLIP-seq
MIRT2517584	hsa-miR-3654	CLIP-seq
MIRT2517586	hsa-miR-3669	CLIP-seq
MIRT1978194	hsa-miR-3673	CLIP-seq
MIRT2517587	hsa-miR-3674	CLIP-seq
MIRT2517588	hsa-miR-383	CLIP-seq
MIRT940707	hsa-miR-3935	CLIP-seq
MIRT2517589	hsa-miR-3936	CLIP-seq
MIRT940708	hsa-miR-411	CLIP-seq
MIRT2517590	hsa-miR-4263	CLIP-seq
MIRT940709	hsa-miR-4270	CLIP-seq
MIRT1978195	hsa-miR-4273	CLIP-seq
MIRT2517591	hsa-miR-4330	CLIP-seq
MIRT2517592	hsa-miR-4427	CLIP-seq
MIRT2517593	hsa-miR-4429	CLIP-seq
MIRT940710	hsa-miR-4441	CLIP-seq
MIRT2517596	hsa-miR-4502	CLIP-seq
MIRT2517597	hsa-miR-4509	CLIP-seq
MIRT2517598	hsa-miR-4639-5p	CLIP-seq
MIRT2517599	hsa-miR-4659a-3p	CLIP-seq
MIRT2517600	hsa-miR-4659b-3p	CLIP-seq
MIRT2517601	hsa-miR-4666-3p	CLIP-seq
MIRT2517602	hsa-miR-4680-3p	CLIP-seq
MIRT1978196	hsa-miR-4719	CLIP-seq
MIRT2517605	hsa-miR-4744	CLIP-seq
MIRT2517607	hsa-miR-4763-5p	CLIP-seq
MIRT1978197	hsa-miR-4768-5p	CLIP-seq
MIRT2517608	hsa-miR-4772-5p	CLIP-seq
MIRT2517609	hsa-miR-4777-3p	CLIP-seq
MIRT2517610	hsa-miR-4796-3p	CLIP-seq
MIRT2517611	hsa-miR-4799-5p	CLIP-seq
MIRT2517616	hsa-miR-519d	CLIP-seq
MIRT2517617	hsa-miR-539	CLIP-seq
MIRT2517618	hsa-miR-548ad	CLIP-seq
MIRT2517619	hsa-miR-548ah	CLIP-seq
MIRT2517620	hsa-miR-576-5p	CLIP-seq
MIRT940711	hsa-miR-577	CLIP-seq
MIRT2517622	hsa-miR-7	CLIP-seq
MIRT2517624	hsa-miR-769-5p	CLIP-seq
MIRT2517625	hsa-miR-93	CLIP-seq

Show/Hide all(10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001405	Component	PAM complex, Tim23 associated import motor	IBA	21873635
GO:0001671	Function	ATPase activator activity	IBA	21873635
GO:0005515	Function	Protein binding	IPI	23263864, 25416956
GO:0009267	Process	Cellular response to starvation	IEA
GO:0016021	Component	Integral component of membrane	IEA
GO:0019216	Process	Regulation of lipid metabolic process	IEA
GO:0030150	Process	Protein import into mitochondrial matrix	IBA	21873635
GO:0031333	Process	Negative regulation of protein-containing complex assembly	IEA
GO:0032781	Process	Positive regulation of ATPase activity	IEA
GO:1902957	Process	Negative regulation of mitochondrial electron transport, NADH to ubiquinone	IEA

MIM	HGNC	e!Ensembl
615339	20325	ENSG00000120675

Protein

UniProt ID

Q9Y5T4

Protein name

DnaJ homolog subfamily C member 15 (Cell growth-inhibiting gene 22 protein) (Methylation-controlled J protein) (MCJ)

Protein function

Negative regulator of the mitochondrial respiratory chain. Prevents mitochondrial hyperpolarization state and restricts mitochondrial generation of ATP (By similarity). Acts as an import component of the TIM23 translocase complex. Stimulates the

Family and domains

Sequence

MAARGVIAPVGESLRYAEYLQPSAKRPDADVDQQRLVRSLIAVGLGVAALAFAGRYAFRI
WKPLEQVITETAKKISTPSFSSYYKGGFEQKMSRREAGLILGVSPSAGKAKIRTAHRRVM
ILNHPDKGGSPYVAAKINEAKDLLETTTKH

Sequence length

150

Interactions

View interactions

Associated diseases

Show/Hide Causal Diseases (1)

Causal
Disease name	Disease term	dbSNP ID	References
Melanoma	melanoma	rs121913315, rs121913323, rs137853080, rs137853081, rs121909232, rs121913388, rs104894094, rs1563902635, rs104894095, rs104894097, rs104894098, rs104894099, rs104894109, rs137854599, rs11547328, rs104894340, rs398123152, rs587780668, rs587782083, rs587782206, rs587782792, rs180177042, rs121913381, rs730881675, rs730881674, rs730881677, rs730881673, rs1800586, rs768966657, rs587778189, rs786204195, rs121913321, rs45476696, rs864622636, rs864622263, rs869025340, rs876660436, rs876658534, rs876658556, rs878853647, rs878853644, rs878853650, rs886041162, rs121913389, rs1057519852, rs121913384, rs121913387, rs1060501266, rs1060501263, rs1060501262, rs749714198, rs1060501265, rs559848002, rs1064794292, rs1131691187, rs1131691186, rs199907548, rs1554654052, rs1554656411, rs1554656624, rs1554653915, rs1554653956, rs1554656253, rs1554654224, rs754806883, rs1057520039, rs1563889584, rs1563889685, rs1287464120, rs1563888944, rs1563892715, rs1563889847, rs141798398, rs1587332338, rs1587340291, rs11552823, rs561034503, rs138677674, rs1819962958, rs1820531050	17145863

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