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THYN1 (thymocyte nuclear protein 1)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
29087
Gene nameGene Name - the full gene name approved by the HGNC.
Thymocyte nuclear protein 1
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
THYN1
SynonymsGene synonyms aliases
HSPC144, MDS012, MY105, THY28, THY28KD
ChromosomeChromosome number
11
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
11q25
SummarySummary of gene provided in NCBI Entrez Gene.
This gene encodes a protein that is highly conserved among vertebrates and plant species and may be involved in the induction of apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT569516 hsa-miR-548ac PAR-CLIP 20371350
MIRT569515 hsa-miR-548bb-3p PAR-CLIP 20371350
MIRT569514 hsa-miR-548d-3p PAR-CLIP 20371350
MIRT569513 hsa-miR-548h-3p PAR-CLIP 20371350
MIRT569512 hsa-miR-548z PAR-CLIP 20371350
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005634 Component Nucleus HDA 21630459
GO:0005634 Component Nucleus IBA 21873635
GO:0005634 Component Nucleus ISS 14601557
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q9P016
Protein name Thymocyte nuclear protein 1 (Thymocyte protein Thy28)
Protein function Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
PDB 3EOP , 5J3E
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01878 EVE
55 219
EVE domain
Domain
Sequence
Sequence length 225
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Prostate cancer Malignant neoplasm of prostate rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 17199135
Unknown
Disease name Disease term dbSNP ID References
Prostatic neoplasms Prostatic Neoplasms 17199135

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