Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
285704 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Repulsive guidance molecule BMP co-receptor b |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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RGMB |
SynonymsGene synonyms aliases
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DRAGON |
ChromosomeChromosome number
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5 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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5q15 |
SummarySummary of gene provided in NCBI Entrez Gene.
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RGMB is a glycosylphosphatidylinositol (GPI)-anchored member of the repulsive guidance molecule family (see RGMA, MIM 607362) and contributes to the patterning of the developing nervous system (Samad et al., 2005 [PubMed 15671031]).[supplied by OMIM, Apr |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
|
UniProt ID |
Q6NW40 |
Protein name |
Repulsive guidance molecule B (DRG11-responsive axonal guidance and outgrowth of neurite) (DRAGON) |
Protein function |
Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Pro |
PDB |
4BQ6
,
4BQ7
,
4BQ8
,
4UHZ
,
4UI0
,
4UI2
,
6Z3H
,
6Z3J
,
6Z3M
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF06535 |
RGM_N |
54 → 222 |
Repulsive guidance molecule (RGM) N-terminus |
Family |
PF06534 |
RGM_C |
226 → 400 |
Repulsive guidance molecule (RGM) C-terminus |
Family |
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Sequence |
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Sequence length |
437 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Prostate cancer |
Malignant neoplasm of prostate |
rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 |
29662167 |
Rheumatoid arthritis |
Rheumatoid Arthritis |
rs3766379, rs3792876, rs2071592, rs3087456, rs587776843, rs1566328963, rs2240340, rs1557787212 |
17568789 |
|
Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Prostatic neoplasms |
Prostatic Neoplasms |
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29662167 |
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