Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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2850 |
Gene nameGene Name - the full gene name approved by the HGNC.
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G protein-coupled receptor 27 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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GPR27 |
SynonymsGene synonyms aliases
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SREB1 |
ChromosomeChromosome number
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3 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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3p13 |
SummarySummary of gene provided in NCBI Entrez Gene.
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GPR27 is a member of the G protein-coupled receptors (GPCRs), a large family of receptors that have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli such as neurotransmitters, hormones, or light in |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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GO ID |
Ontology |
Definition |
Evidence |
Reference |
GO:0004930 |
Function |
G protein-coupled receptor activity |
IBA |
21873635 |
GO:0005886 |
Component |
Plasma membrane |
IBA |
21873635 |
GO:0005886 |
Component |
Plasma membrane |
TAS |
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GO:0007165 |
Process |
Signal transduction |
TAS |
10833454 |
GO:0007186 |
Process |
G protein-coupled receptor signaling pathway |
TAS |
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GO:0016021 |
Component |
Integral component of membrane |
IEA |
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GO:0035774 |
Process |
Positive regulation of insulin secretion involved in cellular response to glucose stimulus |
IEA |
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GO:1900738 |
Process |
Positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway |
IEA |
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
|
UniProt ID |
Q9NS67 |
Protein name |
Probable G-protein coupled receptor 27 (Super conserved receptor expressed in brain 1) |
Protein function |
Orphan receptor. Possible candidate for amine-like G-protein coupled receptor. |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00001 |
7tm_1 |
35 → 337 |
7 transmembrane receptor (rhodopsin family) |
Family |
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Sequence |
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Sequence length |
375 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Malignant mesothelioma |
Malignant mesothelioma |
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25756049 |
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