ZNF615 (zinc finger protein 615)

Gene

• Entrez ID: 284370
• Gene name: Zinc finger protein 615
• Gene symbol: ZNF615
• Synonyms: -
• Chromosome: 19
• Chromosome location: 19q13.41

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1531913	hsa-miR-105	CLIP-seq
MIRT1531914	hsa-miR-135a	CLIP-seq
MIRT1531915	hsa-miR-135b	CLIP-seq
MIRT1531916	hsa-miR-1827	CLIP-seq
MIRT1531917	hsa-miR-24	CLIP-seq
MIRT1531918	hsa-miR-31	CLIP-seq
MIRT1531919	hsa-miR-3185	CLIP-seq
MIRT1531920	hsa-miR-320e	CLIP-seq
MIRT1531921	hsa-miR-34c-3p	CLIP-seq
MIRT1531922	hsa-miR-380	CLIP-seq
MIRT1531923	hsa-miR-382	CLIP-seq
MIRT1531924	hsa-miR-4284	CLIP-seq
MIRT1531925	hsa-miR-4495	CLIP-seq
MIRT1531926	hsa-miR-4511	CLIP-seq
MIRT1531927	hsa-miR-656	CLIP-seq
MIRT1531928	hsa-miR-676	CLIP-seq
MIRT1531929	hsa-miR-7	CLIP-seq
MIRT1531930	hsa-miR-9	CLIP-seq
MIRT1531921	hsa-miR-34c-3p	CLIP-seq
MIRT1531931	hsa-miR-433	CLIP-seq
MIRT2160843	hsa-miR-3616-5p	CLIP-seq
MIRT2160844	hsa-miR-3647-5p	CLIP-seq
MIRT2160845	hsa-miR-4670-3p	CLIP-seq
MIRT2160846	hsa-miR-573	CLIP-seq
MIRT2380008	hsa-miR-1290	CLIP-seq
MIRT2380009	hsa-miR-132	CLIP-seq
MIRT2380010	hsa-miR-144	CLIP-seq
MIRT2380011	hsa-miR-194	CLIP-seq
MIRT2380012	hsa-miR-212	CLIP-seq
MIRT2380013	hsa-miR-3074-5p	CLIP-seq
MIRT2380014	hsa-miR-3124-3p	CLIP-seq
MIRT2380015	hsa-miR-3137	CLIP-seq
MIRT2380016	hsa-miR-3159	CLIP-seq
MIRT2380017	hsa-miR-376a	CLIP-seq
MIRT2380018	hsa-miR-376b	CLIP-seq
MIRT2380019	hsa-miR-4703-3p	CLIP-seq
MIRT2380020	hsa-miR-4742-3p	CLIP-seq
MIRT2380021	hsa-miR-486-5p	CLIP-seq
MIRT1531916	hsa-miR-1827	CLIP-seq
MIRT2464429	hsa-miR-4299	CLIP-seq
MIRT2464430	hsa-miR-548a-3p	CLIP-seq
MIRT2464431	hsa-miR-548e	CLIP-seq
MIRT2464432	hsa-miR-548f	CLIP-seq
MIRT2464433	hsa-miR-582-3p	CLIP-seq
MIRT2672157	hsa-miR-221	CLIP-seq
MIRT2672158	hsa-miR-222	CLIP-seq
MIRT2672159	hsa-miR-3152-3p	CLIP-seq
MIRT2672160	hsa-miR-3163	CLIP-seq
MIRT2672161	hsa-miR-320a	CLIP-seq
MIRT2672162	hsa-miR-320b	CLIP-seq
MIRT2672163	hsa-miR-320c	CLIP-seq
MIRT2672164	hsa-miR-320d	CLIP-seq
MIRT1531921	hsa-miR-34c-3p	CLIP-seq
MIRT1531931	hsa-miR-433	CLIP-seq
MIRT2672165	hsa-miR-4429	CLIP-seq
MIRT2672166	hsa-miR-4778-3p	CLIP-seq
MIRT2672167	hsa-miR-495	CLIP-seq
MIRT2672157	hsa-miR-221	CLIP-seq
MIRT2672158	hsa-miR-222	CLIP-seq
MIRT2672159	hsa-miR-3152-3p	CLIP-seq
MIRT2672160	hsa-miR-3163	CLIP-seq
MIRT2672161	hsa-miR-320a	CLIP-seq
MIRT2672162	hsa-miR-320b	CLIP-seq
MIRT2672163	hsa-miR-320c	CLIP-seq
MIRT2672164	hsa-miR-320d	CLIP-seq
MIRT2672165	hsa-miR-4429	CLIP-seq
MIRT2672167	hsa-miR-495	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	21873635
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IBA	21873635
GO:0005634	Component	Nucleus	IBA	21873635
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA	21873635
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: HGNC
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8N8J6
• Protein name: Zinc finger protein 615
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01352	KRAB	7 → 48	KRAB box	Family
  PF00096	zf-C2H2	232 → 254	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	260 → 282	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	288 → 310	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	318 → 338	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	344 → 366	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	372 → 394	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	400 → 422	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	428 → 450	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	456 → 478	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	484 → 506	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	512 → 534	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	540 → 562	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	568 → 590	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	596 → 618	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	624 → 646	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	680 → 702	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	708 → 730	Zinc finger, C2H2 type	Domain

• Sequence:

  MMQAQESLTLEDVAVDFTWEEWQFLSPAQKDLYRDVMLENYSNLVAVGYQASKPDALSKL
  ERGEETCTTEDEIYSRICSEIRKIDDPLQHHLQNQSIQKSVKQCHEQNMFGNIVNQNKGH
  FLLKQDCDTFDLHEKPLKSNLSFENQKRSSGLKNSAEFNRDGKSLFHANHKQFYTEMKFP
  AIAKPINKSQFIKQQRTHNIENAHVCSECGKAFLKLSQFIDHQRVHTGEKPHVCSMCGKA
  FSRKSRLMDHQRTHTELKHYECTECDKTFLKKSQLNIHQKTHMGGKPYTCSQCGKAFIKK
  CRLIYHQRTHTGEKPHGCSVCGKAFSTKFSLTTHQKTHTGEKPYICSECGKGFIEKRRLT
  AHHRTHTGEKPFICNKCGKGFTLKNSLITHQQTHTGEKLYTCSECGKGFSMKHCLMVHQR
  THTGEKPYKCNECGKGFALKSPLIRHQRTHTGEKPYVCTECRKGFTMKSDLIVHQRTHTA
  EKPYICNDCGKGFTVKSRLIVHQRTHTGEKPYVCGECGKGFPAKIRLMGHQRTHTGEKPY
  ICNECGKGFTEKSHLNVHRRTHTGEKPYVCSECGKGLTGKSMLIAHQRTHTGEKPYICNE
  CGKGFTMKSTLSIHQQTHTGEKPYKCNECDKTFRKKTCLIQHQRFHTGKTSFACTECGKF
  SLRKNDLITHQRIHTGEKPYKCSDCGKAFTTKSGLNVHQRKHTGERPYGCSDCGKAFAHL
  SILVKHRRIHR

• Sequence length: 731

Pathways

Reactome:

Generic Transcription Pathway

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Attention deficit hyperactivity disorder	Attention deficit hyperactivity disorder	rs120074176, rs786205019	23453885
Schizophrenia	Schizophrenia	rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313	23453885

Unknown
Disease name	Disease term	dbSNP ID	References
Bipolar disorder	Bipolar Disorder		23453885
Development disorder	Child Development Disorders, Pervasive		23453885
Mental depression	Major Depressive Disorder	rs587778876, rs587778877	23453885