GeDiPNet: Comprehensive Gene Data - OMIM, HGNC, Ensembl, UniProt, GO, Transcription Factors & miRNA

Home
Browse
- Genes
- Diseases
- Pathways
  - Reactome
  - KEGG
Analysis
Help
Links
FAQ
Contact us

GSDMA (gasdermin A)

Gene

284110

Gasdermin A

GSDMA

FKSG9, GSDM, GSDM1

17q21.1

Show/Hide all(243)

miRTarBase ID	miRNA	Experiments	Reference
MIRT628789	hsa-miR-564	HITS-CLIP	23824327
MIRT628788	hsa-miR-4284	HITS-CLIP	23824327
MIRT628787	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT628786	hsa-miR-7977	HITS-CLIP	23824327
MIRT628789	hsa-miR-564	HITS-CLIP	23824327
MIRT628788	hsa-miR-4284	HITS-CLIP	23824327
MIRT628787	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT628786	hsa-miR-7977	HITS-CLIP	23824327
MIRT628789	hsa-miR-564	HITS-CLIP	23824327
MIRT628788	hsa-miR-4284	HITS-CLIP	23824327
MIRT628787	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT628786	hsa-miR-7977	HITS-CLIP	23824327
MIRT628789	hsa-miR-564	HITS-CLIP	23824327
MIRT628788	hsa-miR-4284	HITS-CLIP	23824327
MIRT628787	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT628786	hsa-miR-7977	HITS-CLIP	23824327
MIRT637708	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT628789	hsa-miR-564	HITS-CLIP	23824327
MIRT628788	hsa-miR-4284	HITS-CLIP	23824327
MIRT628787	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT628786	hsa-miR-7977	HITS-CLIP	23824327
MIRT628789	hsa-miR-564	HITS-CLIP	23824327
MIRT628788	hsa-miR-4284	HITS-CLIP	23824327
MIRT628787	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT628786	hsa-miR-7977	HITS-CLIP	23824327
MIRT628789	hsa-miR-564	HITS-CLIP	23824327
MIRT628788	hsa-miR-4284	HITS-CLIP	23824327
MIRT628787	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT628786	hsa-miR-7977	HITS-CLIP	23824327
MIRT628789	hsa-miR-564	HITS-CLIP	23824327
MIRT628788	hsa-miR-4284	HITS-CLIP	23824327
MIRT628787	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT628786	hsa-miR-7977	HITS-CLIP	23824327
MIRT628789	hsa-miR-564	HITS-CLIP	23824327
MIRT628788	hsa-miR-4284	HITS-CLIP	23824327
MIRT628787	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT628786	hsa-miR-7977	HITS-CLIP	23824327
MIRT628789	hsa-miR-564	HITS-CLIP	23824327
MIRT628788	hsa-miR-4284	HITS-CLIP	23824327
MIRT628787	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT628786	hsa-miR-7977	HITS-CLIP	23824327
MIRT628789	hsa-miR-564	HITS-CLIP	23824327
MIRT628788	hsa-miR-4284	HITS-CLIP	23824327
MIRT628787	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT628786	hsa-miR-7977	HITS-CLIP	23824327
MIRT637708	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT628789	hsa-miR-564	HITS-CLIP	23824327
MIRT628788	hsa-miR-4284	HITS-CLIP	23824327
MIRT628787	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT628786	hsa-miR-7977	HITS-CLIP	23824327
MIRT628789	hsa-miR-564	HITS-CLIP	23824327
MIRT628788	hsa-miR-4284	HITS-CLIP	23824327
MIRT628787	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT628786	hsa-miR-7977	HITS-CLIP	23824327
MIRT628789	hsa-miR-564	HITS-CLIP	23824327
MIRT628788	hsa-miR-4284	HITS-CLIP	23824327
MIRT628787	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT628786	hsa-miR-7977	HITS-CLIP	23824327
MIRT1035682	hsa-miR-1262	CLIP-seq
MIRT1035683	hsa-miR-1273e	CLIP-seq
MIRT1035684	hsa-miR-1285	CLIP-seq
MIRT1035685	hsa-miR-1304	CLIP-seq
MIRT1035686	hsa-miR-145	CLIP-seq
MIRT1035687	hsa-miR-1827	CLIP-seq
MIRT1035688	hsa-miR-24	CLIP-seq
MIRT1035689	hsa-miR-2964a-3p	CLIP-seq
MIRT1035690	hsa-miR-302f	CLIP-seq
MIRT1035691	hsa-miR-3122	CLIP-seq
MIRT1035692	hsa-miR-3187-5p	CLIP-seq
MIRT1035693	hsa-miR-3192	CLIP-seq
MIRT1035694	hsa-miR-3614-5p	CLIP-seq
MIRT1035695	hsa-miR-3689a-3p	CLIP-seq
MIRT1035696	hsa-miR-3689c	CLIP-seq
MIRT1035697	hsa-miR-3913-5p	CLIP-seq
MIRT1035698	hsa-miR-4252	CLIP-seq
MIRT1035699	hsa-miR-4433	CLIP-seq
MIRT1035700	hsa-miR-4649-3p	CLIP-seq
MIRT1035701	hsa-miR-4701-3p	CLIP-seq
MIRT1035702	hsa-miR-4712-5p	CLIP-seq
MIRT1035703	hsa-miR-4722-5p	CLIP-seq
MIRT1035704	hsa-miR-4728-5p	CLIP-seq
MIRT1035705	hsa-miR-4768-3p	CLIP-seq
MIRT1035706	hsa-miR-4786-5p	CLIP-seq
MIRT1035707	hsa-miR-4793-3p	CLIP-seq
MIRT1035708	hsa-miR-4797-5p	CLIP-seq
MIRT1035709	hsa-miR-490-3p	CLIP-seq
MIRT1035710	hsa-miR-508-5p	CLIP-seq
MIRT1035711	hsa-miR-542-3p	CLIP-seq
MIRT1035712	hsa-miR-587	CLIP-seq
MIRT1035713	hsa-miR-612	CLIP-seq
MIRT1035714	hsa-miR-658	CLIP-seq
MIRT1035715	hsa-miR-661	CLIP-seq
MIRT1035716	hsa-miR-665	CLIP-seq
MIRT1035717	hsa-miR-759	CLIP-seq
MIRT1035718	hsa-miR-766	CLIP-seq
MIRT1035719	hsa-miR-770-5p	CLIP-seq
MIRT1035720	hsa-miR-885-5p	CLIP-seq
MIRT1035721	hsa-miR-940	CLIP-seq
MIRT1035683	hsa-miR-1273e	CLIP-seq
MIRT1035684	hsa-miR-1285	CLIP-seq
MIRT1035685	hsa-miR-1304	CLIP-seq
MIRT1035687	hsa-miR-1827	CLIP-seq
MIRT1035689	hsa-miR-2964a-3p	CLIP-seq
MIRT1035690	hsa-miR-302f	CLIP-seq
MIRT1035692	hsa-miR-3187-5p	CLIP-seq
MIRT1035693	hsa-miR-3192	CLIP-seq
MIRT1035695	hsa-miR-3689a-3p	CLIP-seq
MIRT1035696	hsa-miR-3689c	CLIP-seq
MIRT2007066	hsa-miR-3929	CLIP-seq
MIRT1035698	hsa-miR-4252	CLIP-seq
MIRT2007067	hsa-miR-4419b	CLIP-seq
MIRT2007068	hsa-miR-4478	CLIP-seq
MIRT1035700	hsa-miR-4649-3p	CLIP-seq
MIRT1035703	hsa-miR-4722-5p	CLIP-seq
MIRT1035704	hsa-miR-4728-5p	CLIP-seq
MIRT1035705	hsa-miR-4768-3p	CLIP-seq
MIRT1035706	hsa-miR-4786-5p	CLIP-seq
MIRT1035707	hsa-miR-4793-3p	CLIP-seq
MIRT2007069	hsa-miR-485-5p	CLIP-seq
MIRT1035709	hsa-miR-490-3p	CLIP-seq
MIRT1035710	hsa-miR-508-5p	CLIP-seq
MIRT1035713	hsa-miR-612	CLIP-seq
MIRT1035714	hsa-miR-658	CLIP-seq
MIRT1035716	hsa-miR-665	CLIP-seq
MIRT1035718	hsa-miR-766	CLIP-seq
MIRT1035721	hsa-miR-940	CLIP-seq
MIRT1035682	hsa-miR-1262	CLIP-seq
MIRT1035683	hsa-miR-1273e	CLIP-seq
MIRT1035688	hsa-miR-24	CLIP-seq
MIRT1035689	hsa-miR-2964a-3p	CLIP-seq
MIRT1035690	hsa-miR-302f	CLIP-seq
MIRT1035693	hsa-miR-3192	CLIP-seq
MIRT1035695	hsa-miR-3689a-3p	CLIP-seq
MIRT1035696	hsa-miR-3689c	CLIP-seq
MIRT1035698	hsa-miR-4252	CLIP-seq
MIRT2239593	hsa-miR-4503	CLIP-seq
MIRT1035701	hsa-miR-4701-3p	CLIP-seq
MIRT1035703	hsa-miR-4722-5p	CLIP-seq
MIRT1035704	hsa-miR-4728-5p	CLIP-seq
MIRT1035705	hsa-miR-4768-3p	CLIP-seq
MIRT1035707	hsa-miR-4793-3p	CLIP-seq
MIRT1035709	hsa-miR-490-3p	CLIP-seq
MIRT1035710	hsa-miR-508-5p	CLIP-seq
MIRT1035711	hsa-miR-542-3p	CLIP-seq
MIRT1035714	hsa-miR-658	CLIP-seq
MIRT1035715	hsa-miR-661	CLIP-seq
MIRT1035718	hsa-miR-766	CLIP-seq
MIRT1035721	hsa-miR-940	CLIP-seq
MIRT1035683	hsa-miR-1273e	CLIP-seq
MIRT1035687	hsa-miR-1827	CLIP-seq
MIRT1035689	hsa-miR-2964a-3p	CLIP-seq
MIRT1035690	hsa-miR-302f	CLIP-seq
MIRT1035703	hsa-miR-4722-5p	CLIP-seq
MIRT1035705	hsa-miR-4768-3p	CLIP-seq
MIRT1035709	hsa-miR-490-3p	CLIP-seq
MIRT1035721	hsa-miR-940	CLIP-seq
MIRT1035683	hsa-miR-1273e	CLIP-seq
MIRT1035685	hsa-miR-1304	CLIP-seq
MIRT1035687	hsa-miR-1827	CLIP-seq
MIRT1035689	hsa-miR-2964a-3p	CLIP-seq
MIRT1035690	hsa-miR-302f	CLIP-seq
MIRT1035691	hsa-miR-3122	CLIP-seq
MIRT1035693	hsa-miR-3192	CLIP-seq
MIRT1035694	hsa-miR-3614-5p	CLIP-seq
MIRT1035695	hsa-miR-3689a-3p	CLIP-seq
MIRT1035696	hsa-miR-3689c	CLIP-seq
MIRT1035697	hsa-miR-3913-5p	CLIP-seq
MIRT1035699	hsa-miR-4433	CLIP-seq
MIRT2450829	hsa-miR-4440	CLIP-seq
MIRT2450830	hsa-miR-4455	CLIP-seq
MIRT2450831	hsa-miR-4684-5p	CLIP-seq
MIRT1035703	hsa-miR-4722-5p	CLIP-seq
MIRT1035704	hsa-miR-4728-5p	CLIP-seq
MIRT1035705	hsa-miR-4768-3p	CLIP-seq
MIRT1035709	hsa-miR-490-3p	CLIP-seq
MIRT2450832	hsa-miR-548c-3p	CLIP-seq
MIRT2450833	hsa-miR-609	CLIP-seq
MIRT1035714	hsa-miR-658	CLIP-seq
MIRT1035716	hsa-miR-665	CLIP-seq
MIRT1035721	hsa-miR-940	CLIP-seq
MIRT1035683	hsa-miR-1273e	CLIP-seq
MIRT1035685	hsa-miR-1304	CLIP-seq
MIRT1035687	hsa-miR-1827	CLIP-seq
MIRT1035689	hsa-miR-2964a-3p	CLIP-seq
MIRT1035690	hsa-miR-302f	CLIP-seq
MIRT1035691	hsa-miR-3122	CLIP-seq
MIRT1035693	hsa-miR-3192	CLIP-seq
MIRT2543317	hsa-miR-3613-3p	CLIP-seq
MIRT1035694	hsa-miR-3614-5p	CLIP-seq
MIRT1035695	hsa-miR-3689a-3p	CLIP-seq
MIRT1035696	hsa-miR-3689c	CLIP-seq
MIRT2543318	hsa-miR-371-5p	CLIP-seq
MIRT2543319	hsa-miR-371b-5p	CLIP-seq
MIRT1035697	hsa-miR-3913-5p	CLIP-seq
MIRT1035699	hsa-miR-4433	CLIP-seq
MIRT2450829	hsa-miR-4440	CLIP-seq
MIRT2450830	hsa-miR-4455	CLIP-seq
MIRT2450831	hsa-miR-4684-5p	CLIP-seq
MIRT1035703	hsa-miR-4722-5p	CLIP-seq
MIRT1035704	hsa-miR-4728-5p	CLIP-seq
MIRT1035705	hsa-miR-4768-3p	CLIP-seq
MIRT1035708	hsa-miR-4797-5p	CLIP-seq
MIRT1035709	hsa-miR-490-3p	CLIP-seq
MIRT2450832	hsa-miR-548c-3p	CLIP-seq
MIRT2450833	hsa-miR-609	CLIP-seq
MIRT1035714	hsa-miR-658	CLIP-seq
MIRT1035716	hsa-miR-665	CLIP-seq
MIRT1035717	hsa-miR-759	CLIP-seq
MIRT1035721	hsa-miR-940	CLIP-seq
MIRT2682112	hsa-miR-1204	CLIP-seq
MIRT1035683	hsa-miR-1273e	CLIP-seq
MIRT1035684	hsa-miR-1285	CLIP-seq
MIRT1035685	hsa-miR-1304	CLIP-seq
MIRT1035687	hsa-miR-1827	CLIP-seq
MIRT1035689	hsa-miR-2964a-3p	CLIP-seq
MIRT1035690	hsa-miR-302f	CLIP-seq
MIRT1035691	hsa-miR-3122	CLIP-seq
MIRT1035692	hsa-miR-3187-5p	CLIP-seq
MIRT1035693	hsa-miR-3192	CLIP-seq
MIRT2543317	hsa-miR-3613-3p	CLIP-seq
MIRT1035694	hsa-miR-3614-5p	CLIP-seq
MIRT1035695	hsa-miR-3689a-3p	CLIP-seq
MIRT1035696	hsa-miR-3689c	CLIP-seq
MIRT2543318	hsa-miR-371-5p	CLIP-seq
MIRT2543319	hsa-miR-371b-5p	CLIP-seq
MIRT1035697	hsa-miR-3913-5p	CLIP-seq
MIRT1035699	hsa-miR-4433	CLIP-seq
MIRT2450829	hsa-miR-4440	CLIP-seq
MIRT2450830	hsa-miR-4455	CLIP-seq
MIRT2450831	hsa-miR-4684-5p	CLIP-seq
MIRT1035703	hsa-miR-4722-5p	CLIP-seq
MIRT1035704	hsa-miR-4728-5p	CLIP-seq
MIRT1035705	hsa-miR-4768-3p	CLIP-seq
MIRT1035706	hsa-miR-4786-5p	CLIP-seq
MIRT1035708	hsa-miR-4797-5p	CLIP-seq
MIRT1035709	hsa-miR-490-3p	CLIP-seq
MIRT2450832	hsa-miR-548c-3p	CLIP-seq
MIRT2450833	hsa-miR-609	CLIP-seq
MIRT1035713	hsa-miR-612	CLIP-seq
MIRT1035714	hsa-miR-658	CLIP-seq
MIRT1035716	hsa-miR-665	CLIP-seq
MIRT1035717	hsa-miR-759	CLIP-seq
MIRT1035721	hsa-miR-940	CLIP-seq

Show/Hide all(11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001786	Function	Phosphatidylserine binding	IBA	21873635
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005546	Function	Phosphatidylinositol-4,5-bisphosphate binding	IBA	21873635
GO:0005829	Component	Cytosol	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0006915	Process	Apoptotic process	IDA	17471240
GO:0016021	Component	Integral component of membrane	IEA
GO:0042742	Process	Defense response to bacterium	IBA	21873635
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	17471240
GO:0070269	Process	Pyroptosis	IBA	21873635
GO:0070273	Function	Phosphatidylinositol-4-phosphate binding	IBA	21873635

MIM	HGNC	e!Ensembl
611218	13311	ENSG00000167914

Protein

UniProt ID

Q96QA5

Protein name

Gasdermin-A (Gasdermin-1) [Cleaved into: Gasdermin-A, N-terminal (GSDMA-NT); Gasdermin-A, C-terminal (GSDMA-CT)]

Protein function

[Gasdermin-A]: This form constitutes the precursor of the pore-forming protein and acts as a sensor of infection: upon infection by S.pyogenes, specifically cleaved by S.pyogenes effector protein SpeB in epithelial cells, releasing the N-termina

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04598	Gasdermin	3 → 233	Gasdermin pore forming domain	Domain
PF17708	Gasdermin_C	254 → 418	Gasdermin PUB domain	Domain

Sequence

MTMFENVTRALARQLNPRGDLTPLDSLIDFKRFHPFCLVLRKRKSTLFWGARYVRTDYTL
LDVLEPGSSPSDPTDTGNFGFKNMLDTRVEGDVDVPKTVKVKGTAGLSQNSTLEVQTLSV
APKALETVQERKLAADHPFLKEMQDQGENLYVVMEVVETVQEVTLERAGKAEACFSLPFF
APLGLQGSINHKEAVTIPKGCVLAFRVRQLMVKGKDEWDIPHICNDNMQTFPPGEKSGEE
KVILIQASDVGDVHEGFRTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLLGKKKELQDLE
LALEGALDKGHEVTLEALPKDVLLSKEAVGAILYFVGALTELSEAQQKLLVKSMEKKILP
VQLKLVESTMEQNFLLDKEGVFPLQPELLSSLGDEELTLTEALVGLSGLEVQRSGPQYMW
DPDTLPRLCALYAGLSLLQQLTKAS

Sequence length

445

Interactions

View interactions

Associated diseases

Show/Hide Causal Diseases (1)

Causal
Disease name	Disease term	dbSNP ID	References
Asthma	Asthma, Childhood asthma	rs324981, rs121912630, rs150116809, rs4950928, rs708494, rs1581842283	20860503, 22561531, 21907864, 27130862, 24388013, 21804549, 17611496, 24241537

Show/Hide Unknown Diseases (2)

Unknown
Disease name	Disease term	dbSNP ID	References
Eczema	Eczema		30595370
Scleroderma	Systemic Scleroderma		28314753

| © 2021, Biomedical Informatics Centre, NIRRH |
ICMR-National Institute for Research in Reproductive Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Tel: +91-22-24192104, Fax No: +91-22-24139412