Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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283349 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Ras association domain family member 3 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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RASSF3 |
SynonymsGene synonyms aliases
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RASSF5 |
ChromosomeChromosome number
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12 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12q14.2 |
SummarySummary of gene provided in NCBI Entrez Gene.
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The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RA |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
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UniProt ID |
Q86WH2 |
Protein name |
Ras association domain-containing protein 3 |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00788 |
RA |
79 → 187 |
Ras association (RalGDS/AF-6) domain |
Domain |
PF16517 |
Nore1-SARAH |
192 → 231 |
Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain |
Domain |
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Sequence |
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Sequence length |
238 |
Interactions |
View interactions |
Associated diseases
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Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Lung adenocarcinoma |
Adenocarcinoma of lung (disorder) |
rs28934576, rs121913530, rs397516975, rs587776805, rs121913469, rs121913364, rs121913351, rs121913366, rs397516896, rs397516977, rs397516981, rs397517127, rs121913344, rs727504233, rs121913370, rs760043106, rs1057519788, rs1131692238, rs1131692237, rs1554350382 |
28604730 |
Prostate cancer |
Prostate carcinoma, Prostate cancer, familial |
rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 |
29892016 |
Prostate cancer, hereditary |
PROSTATE CANCER, HEREDITARY, 1 |
rs387906327, rs193929331, rs74315365, rs10993994, rs397516896, rs794729219, rs121913349, rs587782641, rs1114167673, rs1597371666, rs2073394466 |
29892016 |
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