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RASSF3 (Ras association domain family member 3)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
283349
Gene nameGene Name - the full gene name approved by the HGNC.
Ras association domain family member 3
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
RASSF3
SynonymsGene synonyms aliases
RASSF5
ChromosomeChromosome number
12
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12q14.2
SummarySummary of gene provided in NCBI Entrez Gene.
The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RA
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT016387 hsa-miR-193b-3p Microarray 20304954
MIRT031332 hsa-miR-18a-5p Sequencing 20371350
MIRT038969 hsa-miR-20a-3p CLASH 23622248
MIRT1292752 hsa-miR-101 CLIP-seq
MIRT1292753 hsa-miR-1197 CLIP-seq
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 20920251, 23455922, 24255178, 24366813, 28514442, 32296183
GO:0005737 Component Cytoplasm IBA 21873635
GO:0005829 Component Cytosol IDA
GO:0005874 Component Microtubule IEA
GO:0005886 Component Plasma membrane IDA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q86WH2
Protein name Ras association domain-containing protein 3
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00788 RA
79 187
Ras association (RalGDS/AF-6) domain
Domain
PF16517 Nore1-SARAH
192 231
Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain
Domain
Sequence
Sequence length 238
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Lung adenocarcinoma Adenocarcinoma of lung (disorder) rs28934576, rs121913530, rs397516975, rs587776805, rs121913469, rs121913364, rs121913351, rs121913366, rs397516896, rs397516977, rs397516981, rs397517127, rs121913344, rs727504233, rs121913370, rs760043106, rs1057519788, rs1131692238, rs1131692237, rs1554350382 28604730
Prostate cancer Prostate carcinoma, Prostate cancer, familial rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 29892016
Prostate cancer, hereditary PROSTATE CANCER, HEREDITARY, 1 rs387906327, rs193929331, rs74315365, rs10993994, rs397516896, rs794729219, rs121913349, rs587782641, rs1114167673, rs1597371666, rs2073394466 29892016

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