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SLC22A24 (solute carrier family 22 member 24)
Gene
Gene Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
283238
Gene nameGene Name - the full gene name approved by the HGNC.
Solute carrier family 22 member 24
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
SLC22A24
SynonymsGene synonyms aliases
NET46
ChromosomeChromosome number
11
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
11q12.3
SummarySummary of gene provided in NCBI Entrez Gene.
SLC22A24 belongs to a large family of transmembrane proteins that function as uniporters, symporters, and antiporters to transport organic ions across cell membranes (Jacobsson et al., 2007 [PubMed 17714910]).[supplied by OMIM, Mar 2008]
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0008202 Process Steroid metabolic process IDA 31553721
GO:0015711 Process Organic anion transport IBA 21873635
GO:0016021 Component Integral component of membrane IEA
GO:0022857 Function Transmembrane transporter activity IEA
GO:0035382 Process Sterol transmembrane transport IDA 31553721
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Associated diseases
MIM
HGNC
e!Ensembl
Protein
Gene Gene ontology Other IDs Protein Associated diseases
UniProt ID Q8N4F4
Protein name Steroid transmembrane transporter SLC22A24 (Solute carrier family 22 member 24)
Protein function Steroid transmembrane transporter that functions in the reabsorption of conjugated steroids in the kidney and is involved in steroid homeostasis. ; [Isoform 2]: Similar uptake function as Isoform 1. ; [Isoform 3]: Lack of transporter activity.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07690 MFS_1
16 → 312
Major Facilitator Superfamily
 Family
Sequence 
MGFDVLLDQVGGMGRFQICLIAFFCITNILLFPNIVLENFTAFTPSHRCWVPLLDNDTVS
DNDTGTLSKDDLLRISIPLDSNLRPQKCQRFIHPQWQLLHLNGTFPNTNEPDTEPCVDGW
VYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCF
LQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLLCS
YSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFLSSWKMVESARWLIINNQLDEGLKELR
RVAHINGKKNTEETLTTELVRSTMKKELDAVRIKTSIFSLFRAPKLRMRVFGLCFVRFAI
TVPFYGLILNLQHLGSNVSLFQILCGAVTFTARCVSLLTLNHMGRRISQILFTFPVGLFI
LVNTFLPQEMQILRVVLATLGIGSVSAASNSASVHHNELVPTILRSTVAGINAVSGRTGA
ALAPLLMTLMAYSPHLPWISYGVFPILAVPVILLLPETRDLPLPNTIQDVENDRKDSRNI
KQEDTCMKVTQF
Sequence length 552
Interactions View interactions
Associated diseases
Gene Gene ontology Other IDs Protein Associated diseases
Unknown
Disease name Disease term dbSNP ID References
Kidney failure Kidney Failure, Acute 26230185, 23649842
Acute kidney insufficiency Acute Kidney Insufficiency 26230185, 23649842

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