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CCR10 (C-C motif chemokine receptor 10)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
2826
Gene nameGene Name - the full gene name approved by the HGNC.
C-C motif chemokine receptor 10
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
CCR10
SynonymsGene synonyms aliases
GPR2
ChromosomeChromosome number
17
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
17q21.2
SummarySummary of gene provided in NCBI Entrez Gene.
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chem
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0004930 Function G protein-coupled receptor activity TAS 7851889
GO:0005515 Function Protein binding IPI 26941067, 32296183
GO:0005783 Component Endoplasmic reticulum IDA
GO:0005886 Component Plasma membrane TAS
GO:0005887 Component Integral component of plasma membrane TAS 7851889
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID P46092
Protein name C-C chemokine receptor type 10 (C-C CKR-10) (CC-CKR-10) (CCR-10) (G-protein coupled receptor 2)
Protein function Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00001 7tm_1
58 310
7 transmembrane receptor (rhodopsin family)
Family
Sequence
Sequence length 362
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
KEGG
 
Reactome
  Cytokine-cytokine receptor interaction
Viral protein interaction with cytokine and cytokine receptor
Chemokine signaling pathway
Intestinal immune network for IgA production
  Chemokine receptors bind chemokines
G alpha (i) signalling events
Associated diseases
Unknown
Disease name Disease term dbSNP ID References
Grand mal status epilepticus Grand Mal Status Epilepticus 17181556
Nonconvulsive status epilepticus Non-Convulsive Status Epilepticus 17181556
Petit mal status Petit mal status 17181556
Status epilepticus Status Epilepticus, Complex Partial Status Epilepticus, Status Epilepticus, Subclinical 17181556

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