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SLCO3A1 (solute carrier organic anion transporter family member 3A1)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
28232
Gene nameGene Name - the full gene name approved by the HGNC.
Solute carrier organic anion transporter family member 3A1
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
SLCO3A1
SynonymsGene synonyms aliases
OATP-D, OATP-RP3, OATP3A1, OATPD, OATPRP3, SLC21A11
ChromosomeChromosome number
15
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
15q26.1
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT024914 hsa-miR-215-5p Microarray 19074876
MIRT026667 hsa-miR-192-5p Microarray 19074876
MIRT051495 hsa-let-7e-5p CLASH 23622248
MIRT038665 hsa-miR-218-1-3p CLASH 23622248
MIRT699236 hsa-miR-6758-5p HITS-CLIP 23313552
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001934 Process Positive regulation of protein phosphorylation IMP 24945726
GO:0005886 Component Plasma membrane IDA 21278488
GO:0005886 Component Plasma membrane TAS
GO:0005887 Component Integral component of plasma membrane IBA 21873635
GO:0015347 Function Sodium-independent organic anion transmembrane transporter activity IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q9UIG8
Protein name Solute carrier organic anion transporter family member 3A1 (OATP3A1) (Organic anion transporter polypeptide-related protein 3) (OATP-RP3) (OATPRP3) (Organic anion-transporting polypeptide D) (OATP-D) (PGE1 transporter) (Sodium-independent organic anion tr
Protein function Putative organic anion antiporter with apparent broad substrate specificity. Recognizes various substrates including thyroid hormone L-thyroxine, prostanoids such as prostaglandin E1 and E2, bile acids such as taurocholate, glycolate and glycoch
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03137 OATP
41 622
Organic Anion Transporter Polypeptide (OATP) family
Family
PF07648 Kazal_2
472 513
Kazal-type serine protease inhibitor domain
Domain
Sequence
Sequence length 710
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
Reactome
    Transport of organic anions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Lymphoblastic leukemia Precursor Cell Lymphoblastic Leukemia Lymphoma rs387906351, rs104894562, rs398122513, rs398122840, rs398123063, rs1057524466, rs1064796115, rs1064795660, rs1064793129, rs1064796227, rs1567887558, rs1161194345, rs1597558200, rs1406320425, rs1597566470, rs1597566699, rs1597567692, rs1597567985, rs1438890364, rs1288977950, rs1597552140, rs1597566356, rs1597566726, rs1597568117, rs2069719445, rs2069729948, rs2070018439, rs745708044, rs1169577591 22076464

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