GOLGB1 (golgin B1)

Gene

• Entrez ID: 2804
• Gene name: Golgin B1
• Gene symbol: GOLGB1
• Synonyms: GCP, GCP372, GOLIM1
• Chromosome: 3
• Chromosome location: 3q13.33

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT004202	hsa-miR-197-3p	Microarray	16822819
MIRT017250	hsa-miR-335-5p	Microarray	18185580
MIRT440541	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440540	hsa-miR-544a	HITS-CLIP	24374217
MIRT440541	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440540	hsa-miR-544a	HITS-CLIP	24374217
MIRT1026892	hsa-miR-1265	CLIP-seq
MIRT1026893	hsa-miR-1275	CLIP-seq
MIRT1026894	hsa-miR-1278	CLIP-seq
MIRT1026895	hsa-miR-140-3p	CLIP-seq
MIRT1026896	hsa-miR-1915	CLIP-seq
MIRT1026897	hsa-miR-197	CLIP-seq
MIRT1026898	hsa-miR-21	CLIP-seq
MIRT1026899	hsa-miR-2392	CLIP-seq
MIRT1026900	hsa-miR-335	CLIP-seq
MIRT1026901	hsa-miR-34b	CLIP-seq
MIRT1026902	hsa-miR-3613-5p	CLIP-seq
MIRT1026903	hsa-miR-4302	CLIP-seq
MIRT1026904	hsa-miR-4433	CLIP-seq
MIRT1026905	hsa-miR-4459	CLIP-seq
MIRT1026906	hsa-miR-4496	CLIP-seq
MIRT1026907	hsa-miR-4525	CLIP-seq
MIRT1026908	hsa-miR-4665-5p	CLIP-seq
MIRT1026909	hsa-miR-4694-5p	CLIP-seq
MIRT1026910	hsa-miR-4723-5p	CLIP-seq
MIRT1026911	hsa-miR-4726-3p	CLIP-seq
MIRT1026912	hsa-miR-4728-5p	CLIP-seq
MIRT1026913	hsa-miR-4768-3p	CLIP-seq
MIRT1026914	hsa-miR-590-5p	CLIP-seq
MIRT1026915	hsa-miR-625	CLIP-seq
MIRT1026916	hsa-miR-873	CLIP-seq
MIRT1556464	hsa-miR-3064-5p	CLIP-seq
MIRT2004541	hsa-miR-1	CLIP-seq
MIRT2004542	hsa-miR-1343	CLIP-seq
MIRT2004543	hsa-miR-206	CLIP-seq
MIRT2004544	hsa-miR-3673	CLIP-seq
MIRT2004545	hsa-miR-3690	CLIP-seq
MIRT2004546	hsa-miR-3942-3p	CLIP-seq
MIRT2004547	hsa-miR-4254	CLIP-seq
MIRT2004548	hsa-miR-4279	CLIP-seq
MIRT2004549	hsa-miR-4438	CLIP-seq
MIRT2004550	hsa-miR-4470	CLIP-seq
MIRT2004551	hsa-miR-4684-5p	CLIP-seq
MIRT2004552	hsa-miR-4742-5p	CLIP-seq
MIRT1026913	hsa-miR-4768-3p	CLIP-seq
MIRT2004553	hsa-miR-5095	CLIP-seq
MIRT2004554	hsa-miR-613	CLIP-seq
MIRT2004555	hsa-miR-942	CLIP-seq
MIRT2237328	hsa-miR-1266	CLIP-seq
MIRT1026894	hsa-miR-1278	CLIP-seq
MIRT1026898	hsa-miR-21	CLIP-seq
MIRT2237329	hsa-miR-24	CLIP-seq
MIRT2237330	hsa-miR-298	CLIP-seq
MIRT1556464	hsa-miR-3064-5p	CLIP-seq
MIRT2237331	hsa-miR-3065-5p	CLIP-seq
MIRT2237332	hsa-miR-3120-3p	CLIP-seq
MIRT2237333	hsa-miR-3123	CLIP-seq
MIRT2237334	hsa-miR-3127-5p	CLIP-seq
MIRT2237335	hsa-miR-3152-3p	CLIP-seq
MIRT2237336	hsa-miR-3155	CLIP-seq
MIRT2237337	hsa-miR-3155b	CLIP-seq
MIRT1026900	hsa-miR-335	CLIP-seq
MIRT2237338	hsa-miR-3545-5p	CLIP-seq
MIRT2237339	hsa-miR-3607-5p	CLIP-seq
MIRT2237340	hsa-miR-3684	CLIP-seq
MIRT2237341	hsa-miR-3918	CLIP-seq
MIRT2237342	hsa-miR-3973	CLIP-seq
MIRT1026903	hsa-miR-4302	CLIP-seq
MIRT2237343	hsa-miR-4330	CLIP-seq
MIRT1026904	hsa-miR-4433	CLIP-seq
MIRT2237344	hsa-miR-4436b-3p	CLIP-seq
MIRT1026905	hsa-miR-4459	CLIP-seq
MIRT2237345	hsa-miR-4503	CLIP-seq
MIRT2237346	hsa-miR-4518	CLIP-seq
MIRT2237347	hsa-miR-4666-5p	CLIP-seq
MIRT1026909	hsa-miR-4694-5p	CLIP-seq
MIRT1026913	hsa-miR-4768-3p	CLIP-seq
MIRT2237348	hsa-miR-484	CLIP-seq
MIRT2237349	hsa-miR-545	CLIP-seq
MIRT2237350	hsa-miR-562	CLIP-seq
MIRT1026914	hsa-miR-590-5p	CLIP-seq
MIRT2237351	hsa-miR-668	CLIP-seq
MIRT2237352	hsa-miR-936	CLIP-seq
MIRT2004555	hsa-miR-942	CLIP-seq
MIRT2237343	hsa-miR-4330	CLIP-seq
MIRT2237345	hsa-miR-4503	CLIP-seq
MIRT1026894	hsa-miR-1278	CLIP-seq
MIRT1026898	hsa-miR-21	CLIP-seq
MIRT1556464	hsa-miR-3064-5p	CLIP-seq
MIRT2237332	hsa-miR-3120-3p	CLIP-seq
MIRT2237335	hsa-miR-3152-3p	CLIP-seq
MIRT1026900	hsa-miR-335	CLIP-seq
MIRT2541026	hsa-miR-3617	CLIP-seq
MIRT2541027	hsa-miR-3662	CLIP-seq
MIRT2237340	hsa-miR-3684	CLIP-seq
MIRT2004546	hsa-miR-3942-3p	CLIP-seq
MIRT2237342	hsa-miR-3973	CLIP-seq
MIRT1026903	hsa-miR-4302	CLIP-seq
MIRT1026904	hsa-miR-4433	CLIP-seq
MIRT2004549	hsa-miR-4438	CLIP-seq
MIRT1026905	hsa-miR-4459	CLIP-seq
MIRT2541028	hsa-miR-4464	CLIP-seq
MIRT2004550	hsa-miR-4470	CLIP-seq
MIRT2541029	hsa-miR-4494	CLIP-seq
MIRT2541030	hsa-miR-4539	CLIP-seq
MIRT2541031	hsa-miR-4693-3p	CLIP-seq
MIRT1026909	hsa-miR-4694-5p	CLIP-seq
MIRT2541032	hsa-miR-4698	CLIP-seq
MIRT2541033	hsa-miR-4705	CLIP-seq
MIRT2541034	hsa-miR-4724-5p	CLIP-seq
MIRT2004552	hsa-miR-4742-5p	CLIP-seq
MIRT2541035	hsa-miR-4748	CLIP-seq
MIRT2541036	hsa-miR-4766-5p	CLIP-seq
MIRT1026913	hsa-miR-4768-3p	CLIP-seq
MIRT2541037	hsa-miR-4797-3p	CLIP-seq
MIRT2541038	hsa-miR-494	CLIP-seq
MIRT2541039	hsa-miR-499a-5p	CLIP-seq
MIRT2004553	hsa-miR-5095	CLIP-seq
MIRT2237349	hsa-miR-545	CLIP-seq
MIRT2237350	hsa-miR-562	CLIP-seq
MIRT1026914	hsa-miR-590-5p	CLIP-seq
MIRT2541040	hsa-miR-641	CLIP-seq
MIRT2541041	hsa-miR-647	CLIP-seq
MIRT2237351	hsa-miR-668	CLIP-seq
MIRT1026894	hsa-miR-1278	CLIP-seq
MIRT1026898	hsa-miR-21	CLIP-seq
MIRT1556464	hsa-miR-3064-5p	CLIP-seq
MIRT2237332	hsa-miR-3120-3p	CLIP-seq
MIRT2237335	hsa-miR-3152-3p	CLIP-seq
MIRT1026900	hsa-miR-335	CLIP-seq
MIRT2541027	hsa-miR-3662	CLIP-seq
MIRT2237340	hsa-miR-3684	CLIP-seq
MIRT2237342	hsa-miR-3973	CLIP-seq
MIRT1026903	hsa-miR-4302	CLIP-seq
MIRT1026904	hsa-miR-4433	CLIP-seq
MIRT2004549	hsa-miR-4438	CLIP-seq
MIRT1026905	hsa-miR-4459	CLIP-seq
MIRT2004550	hsa-miR-4470	CLIP-seq
MIRT2541029	hsa-miR-4494	CLIP-seq
MIRT2541031	hsa-miR-4693-3p	CLIP-seq
MIRT1026909	hsa-miR-4694-5p	CLIP-seq
MIRT2541032	hsa-miR-4698	CLIP-seq
MIRT2541033	hsa-miR-4705	CLIP-seq
MIRT2004552	hsa-miR-4742-5p	CLIP-seq
MIRT1026913	hsa-miR-4768-3p	CLIP-seq
MIRT2541038	hsa-miR-494	CLIP-seq
MIRT2541039	hsa-miR-499a-5p	CLIP-seq
MIRT2004553	hsa-miR-5095	CLIP-seq
MIRT2237349	hsa-miR-545	CLIP-seq
MIRT2237350	hsa-miR-562	CLIP-seq
MIRT1026914	hsa-miR-590-5p	CLIP-seq
MIRT2237351	hsa-miR-668	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	TAS
GO:0003723	Function	RNA binding	HDA	22658674
GO:0005515	Function	Protein binding	IPI	14980500, 16169070
GO:0005793	Component	Endoplasmic reticulum-Golgi intermediate compartment	IBA	21873635
GO:0005793	Component	Endoplasmic reticulum-Golgi intermediate compartment	IDA	15308636
GO:0005794	Component	Golgi apparatus	IDA	22572157, 22792322
GO:0005795	Component	Golgi stack	TAS	7691276
GO:0005801	Component	Cis-Golgi network	IBA	21873635
GO:0005801	Component	Cis-Golgi network	IEA
GO:0006355	Process	Regulation of transcription, DNA-templated	IEA
GO:0006888	Process	Endoplasmic reticulum to Golgi vesicle-mediated transport	TAS
GO:0007030	Process	Golgi organization	TAS	7691276
GO:0016020	Component	Membrane	HDA	19946888
GO:0016021	Component	Integral component of membrane	IEA
GO:0043565	Function	Sequence-specific DNA binding	IEA
GO:1905793	Process	Protein localization to pericentriolar material	IMP	25205765

Other IDs

• MIM: 602500
• HGNC: 4429
• e!Ensembl: ENSG00000173230

Protein

• UniProt ID: Q14789
• Protein name: Golgin subfamily B member 1 (372 kDa Golgi complex-associated protein) (GCP372) (Giantin) (Macrogolgin)
• Protein function: May participate in forming intercisternal cross-bridges of the Golgi complex.
• Sequence:

  MLSRLSGLANVVLHELSGDDDTDQNMRAPLDPELHQESDMEFNNTTQEDVQERLAYAEQL
  VVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGT
  VLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSST
  EMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQL
  VTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQME
  AEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELE
  SRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTI
  QQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVEL
  ENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSA
  EESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQ
  MEGEGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVE
  LKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISN
  LNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQR
  RLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQL
  QNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKD
  QQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLK
  QNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLK
  DESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDL
  EEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVAL
  VKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERH
  LREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSST
  PGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVE
  LELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ
  IAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALH
  TQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENK
  SLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLL
  ENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQ
  SYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRK
  FAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSK
  KFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQ
  DSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNK
  EFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKD
  DLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKT
  KVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALER
  TVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLK
  LKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIG
  EIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQ
  SKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCD
  TLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEG
  IIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIA
  ELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLD
  SFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMD
  DLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESE
  EANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEE
  VHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETET
  AEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRK
  YDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHL
  SSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLK
  KAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQ
  ENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQP
  LKVQYQRQASPETSASPDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLE
  EKNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQELQAGPLNIDVAPGAPQEKNGV
  HRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAAENALSVAEEQIRR
  LEHSEWDSSRTPIIGSCGTQEQALLIDLTSNSCRRTRSGVGWKRVLRSLCHSRTRVPLLA
  AIYFLMIHVLLILCFTGHL

• Sequence length: 3259

Pathways

Reactome:

Golgi Associated Vesicle Biogenesis
COPI-mediated anterograde transport

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158, rs80357524, rs80357115, rs80357945, rs80357729, rs80357609, rs80357259, rs80357981, rs80358063, rs80357389, rs80356862, rs80359876, rs80357580, rs80358053, rs80358089, rs80187739, rs397507241, rs80358069, rs80357590, rs80357284, rs80357941, rs80359261, rs80359272, rs80359276, rs276174813, rs80358474, rs80359316, rs1555282969, rs80359388, rs80359499, rs80359505, rs80359520, rs80359526, rs80359533, rs56253082, rs80358824, rs80359554, rs80359636, rs80359651, rs80359659, rs80359011, rs80359012, rs80359013, rs80359718, rs397507410, rs81002812, rs80359730, rs80359152, rs80359159, rs397507419, rs28897759, rs80359211, rs80359775, rs397514577, rs397507584, rs80358435, rs80358456, rs80359340, rs80359343, rs80359365, rs80358579, rs397507670, rs80358593, rs80359406, rs80359444, rs80359454, rs276174853, rs276174854, rs80359483, rs80359537, rs80358815, rs80358843, rs80359558, rs80359560, rs80359594, rs80358893, rs28897743, rs397507900, rs397507906, rs397507918, rs80358971, rs80358981, rs397507941, rs80359030, rs80359035, rs41293511, rs397507396, rs81002806, rs80359112, rs397508006, rs81002893, rs45580035, rs80359760, rs397508051, rs80359772, rs4987049, rs80359777, rs80357770, rs397508867, rs62625303, rs397508874, rs80357506, rs80357287, rs273898674, rs80358042, rs80358083, rs80357058, rs41286296, rs80357960, rs80356945, rs80357223, rs386134270, rs80358116, rs80357856, rs80357424, rs397509050, rs80357485, rs80357966, rs397509067, rs80357310, rs80356866, rs80357260, rs80357437, rs80358023, rs80358086, rs80357133, rs80356993, rs80357997, rs80357239, rs80357227, rs397509243, rs80356969, rs80356959, rs63750617, rs63751319, rs587779315, rs200640585, rs398122546, rs80357543, rs398122687, rs80359328, rs398122779, rs398122783, rs62517194, rs80358029, rs515726060, rs180177103, rs180177111, rs180177133, rs587776527, rs180177135, rs180177136, rs515726117, rs587779813, rs587779909, rs587780024, rs587780100, rs28909982, rs121908698, rs180177100, rs587780210, rs587780240, rs587780639, rs587781269, rs587781353, rs587781471, rs587781658, rs587781697, rs587781730, rs587781894, rs587781948, rs587782005, rs587782011, rs200928781, rs587781558, rs370228071, rs587782245, rs587782401, rs180177110, rs587782504, rs72552322, rs587782531, rs587782620, rs587782680, rs587782774, rs587782818, rs730881411, rs730881389, rs564652222, rs397507768, rs587776419, rs730881868, rs730881940, rs56383036, rs758972589, rs201089102, rs730881348, rs786202608, rs786201886, rs786203318, rs786203775, rs786203714, rs786202033, rs750621215, rs786203884, rs786203650, rs772821016, rs863224521, rs864622223, rs864622655, rs375699023, rs876659572, rs768362387, rs876659535, rs876658957, rs483353072, rs876659435, rs267608041, rs876661113, rs730881369, rs878853535, rs772228129, rs878855122, rs760551339, rs80359596, rs397509222, rs886039630, rs886039683, rs886040828, rs587781799, rs886040374, rs886040649, rs397507967, rs878854957, rs886040043, rs1057517589, rs1060502769, rs866380588, rs863224765, rs1064793243, rs747563556, rs1555074976, rs1064795885, rs753961188, rs1064794708, rs869312772, rs1064793887, rs1131690820, rs1135401928, rs1135401868, rs1135401859, rs1553370324, rs397507630, rs1555283160, rs1555283251, rs1555283262, rs1555283361, rs1555286298, rs1555288462, rs886040950, rs1555289566, rs776323117, rs80357123, rs1555579627, rs1555580697, rs80358054, rs1555593302, rs1328985852, rs763470424, rs1555139694, rs878854697, rs1555461217, rs1555461765, rs774684620, rs766416564, rs1554558613, rs1305740166, rs1555461460, rs1555461407, rs1555461586, rs1555567202, rs1555607022, rs1555069815, rs1442299125, rs1474786480, rs1555084947, rs1555457867, rs141087784, rs1482641121, rs1564830522, rs1565469955, rs1565503137, rs864622613, rs755263466, rs757679199, rs1593903166, rs1597801649, rs1603293306, rs879253880, rs80358754, rs1597062038, rs45494092, rs1603275367, rs887358871, rs1597091518, rs1966967065, rs1064793049, rs2082872908, rs2085078278, rs2072475243