Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
2768 |
Gene nameGene Name - the full gene name approved by the HGNC.
|
G protein subunit alpha 12 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
GNA12 |
SynonymsGene synonyms aliases
|
HG1M1, NNX3, RMP, gep |
ChromosomeChromosome number
|
7 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
7p22.3-p22.2 |
miRNAmiRNA information provided by mirtarbase database.
|
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
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Protein
|
UniProt ID |
Q03113 |
Protein name |
Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12) |
Protein function |
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:12515866, PubMed:15240885, PubMed:15525651, PubMed:16705036, PubMed:16787920, PubMed:17565996, PubMed:2 |
PDB |
7YDJ
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00503 |
G-alpha |
37 → 370 |
G-protein alpha subunit |
Domain |
|
Sequence |
|
Sequence length |
381 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
|
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Associated diseases
|
Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Inflammatory bowel disease |
Inflammatory Bowel Diseases |
rs137853579, rs137853580, rs121909601, rs149491038, rs368287711, rs387907326, rs587777338, rs758439420, rs139868987, rs750447828, rs368138379, rs1329427406, rs1264862631, rs1192830343, rs1373354533, rs1419560997, rs1591263883, rs1989014468 |
26192919, 28067908 |
Psoriasis |
Psoriasis |
rs281875215, rs587777763, rs281875213, rs281875212 |
26974007 |
|
Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Ankylosing spondylitis |
Ankylosing spondylitis |
|
26974007 |
Cholangitis |
Cholangitis, Sclerosing |
|
26974007 |
Crohn disease |
Crohn Disease |
rs2066847, rs2066844, rs886052047, rs5743265, rs111608429, rs104895438 |
26974007 |
Myocardial ischemia |
Myocardial Ischemia |
|
16214533 |
Nonorganic psychosis |
Nonorganic psychosis |
|
25266742 |
Psychosis |
Psychotic Disorders |
|
25266742 |
Ulcerative colitis |
Ulcerative Colitis |
|
26974007, 23128233, 21297633, 26192919, 28067908 |
|