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DHDH (dihydrodiol dehydrogenase)
Gene
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
27294
Gene nameGene Name - the full gene name approved by the HGNC.
Dihydrodiol dehydrogenase
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
DHDH
SynonymsGene synonyms aliases
2DD, HUM2DD
ChromosomeChromosome number
19
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
19q13.33
SummarySummary of gene provided in NCBI Entrez Gene.
This gene encodes an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars. These enzymes catalyze the NADP1-linked oxidation of tra
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0005975 Process Carbohydrate metabolic process TAS 10477285
GO:0008746 Function NAD(P)+ transhydrogenase activity TAS 10477285
GO:0009055 Function Electron transfer activity TAS 10477285
GO:0022900 Process Electron transport chain IEA
GO:0042843 Process D-xylose catabolic process IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
MIM
HGNC
e!Ensembl
Protein
Gene Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q9UQ10
Protein name Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) (D-xylose 1-dehydrogenase) (D-xylose-NADP dehydrogenase) (EC 1.1.1.179) (Dimeric dihydrodiol dehydrogenase) (Hum2DD)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01408 GFO_IDH_MocA
3 → 123
Oxidoreductase family, NAD-binding Rossmann fold
 Family
PF02894 GFO_IDH_MocA_C
136 → 265
Oxidoreductase family, C-terminal alpha/beta domain
 Domain
Sequence
Sequence length 334
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
 
KEGG
  
  Pentose and glucuronate interconversions
Metabolism of xenobiotics by cytochrome P450
Metabolic pathways 		 
Associated diseases
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Causal
Disease name Disease term dbSNP ID References
Prostate cancer Malignant neoplasm of prostate rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 21716162
Unknown
Disease name Disease term dbSNP ID References
Prostatic neoplasms Prostatic Neoplasms 21716162

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