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GGT7 (gamma-glutamyltransferase 7)
Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
2686
Gene nameGene Name - the full gene name approved by the HGNC.
Gamma-glutamyltransferase 7
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
GGT7
SynonymsGene synonyms aliases
D20S101, GGT4, GGTL3, GGTL5
ChromosomeChromosome number
20
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
20q11.22
SummarySummary of gene provided in NCBI Entrez Gene.
This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. [provided by RefSeq, Jul 2008]
miRNAmiRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
miRTarBase ID miRNA Experiments Reference
MIRT043545 hsa-miR-331-3p CLASH 23622248
MIRT611133 hsa-miR-197-3p HITS-CLIP 23824327
MIRT611133 hsa-miR-197-3p HITS-CLIP 28735896
MIRT611134 hsa-miR-6511b-3p HITS-CLIP 23824327
MIRT611134 hsa-miR-6511b-3p HITS-CLIP 28735896
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0000048 Function Peptidyltransferase activity IBA 21873635
GO:0005515 Function Protein binding IPI 25416956, 25910212, 31515488, 32296183
GO:0005886 Component Plasma membrane IBA 21873635
GO:0006412 Process Translation IEA
GO:0006508 Process Proteolysis IEA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM
HGNC
e!Ensembl
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q9UJ14
Protein name Glutathione hydrolase 7 (EC 3.4.19.13) (Gamma-glutamyltransferase 7) (GGT 7) (EC 2.3.2.2) (Gamma-glutamyltransferase-like 3) (Gamma-glutamyltransferase-like 5) (Gamma-glutamyltranspeptidase 7) [Cleaved into: Glutathione hydrolase 7 heavy chain; Glutathione hydrolase 7 light chain]
Protein function Cleaves glutathione conjugates.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01019 G_glu_transpept
154 → 655
Domain
Sequence
Sequence length 662
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
 
KEGG
  
Reactome
  Taurine and hypotaurine metabolism
Glutathione metabolism
Metabolic pathways 		  Glutathione synthesis and recycling
Aflatoxin activation and detoxification
Associated diseases
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Causal
Disease name Disease term dbSNP ID References
Coronary artery disease Coronary Artery Disease rs137852988, rs121918313, rs-1, rs121918529, rs121918531, rs137852340, rs405509, rs1555800701, rs1215189537 29212778

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