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CNNM3 (cyclin and CBS domain divalent metal cation transport mediator 3)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
26505
Gene nameGene Name - the full gene name approved by the HGNC.
Cyclin and CBS domain divalent metal cation transport mediator 3
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
CNNM3
SynonymsGene synonyms aliases
ACDP3, SLC70A3
ChromosomeChromosome number
2
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2q11.2
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT020730 hsa-miR-155-5p Proteomics 18668040
MIRT027933 hsa-miR-96-5p Sequencing 20371350
MIRT052005 hsa-let-7b-5p CLASH 23622248
MIRT692307 hsa-miR-3156-5p HITS-CLIP 23313552
MIRT692306 hsa-miR-1285-5p HITS-CLIP 23313552
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 16189514, 19060904, 21516116, 25416956, 32296183
GO:0005886 Component Plasma membrane IBA 21873635
GO:0006810 Process Transport IBA 21873635
GO:0006811 Process Ion transport IEA
GO:0016020 Component Membrane HDA 19946888
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q8NE01
Protein name Metal transporter CNNM3 (Ancient conserved domain-containing protein 3) (Cyclin-M3)
Protein function Probable metal transporter.
PDB 5K22 , 5K23 , 5K25 , 5TSR , 6DFD , 6MN6 , 6WUR
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00571 CBS
382 446
CBS domain
Domain
Sequence
MAAAVAAAGRLGWLFAALCLGNAAGEAAPGPRVLGFCLEEDGAAGAGWVRGGAARDTPDA
TFLLRLFGPGFANSSWSWVAPEGAGCREEAASPAGEWRALLRLRLRAEAVRPHSALLAVR
VEPGGGAAEEAAPPWALGLGAAGLLALAALARGLQLSALALAPAEVQVLRESGSEAERAA
ARRLEPARRWAGCALGALLLLASLAQAALAVLLYRAAGQRAVPAVLGSAGLVFLVGEVVP
AAVSGRWTLALAPRALGLSRLAVLLTLPVALPVGQLLELAARPGRLRERVLELARGGGDP
YSDLSKGVLRCRTVEDVLTPLEDCFMLDASTVLDFGVLASIMQSGHTRIPVYEEERSNIV
DMLYLKDLAFVDPEDCTPLSTITRFYNHPLHFVFNDTKLDAVLEEFKRGKSHLAIVQKVN
NEGEGDPFYEVLGLVTLEDVIEEIIR
SEILDESEDYRDTVVKRKPASLMAPLKRKEEFSL
FKVSDDEYKVTISPQLLLATQRFLSREVDVFSPLRISEKVLLHLLKHPSVNQEVRFDESN
RLATHHYLYQRSQPVDYFILILQGRVEVEIGKEGLKFENGAFTYYGVSALTVPSSVHQSP
VSSLQPIRHDLQPDPGDGTHSSAYCPDYTVRALSDLQLIKVTRLQYLNALLATRAQNLPQ
SPENTDLQVIPGSQTRLLGEKTTTAAGSSHSRPGVPVEGSPGRNPGV
Sequence length 707
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Schizophrenia Schizophrenia rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 26198764
Unknown
Disease name Disease term dbSNP ID References
Depressed bipolar disorder Depressed bipolar I disorder 31043756

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