PHF19 (PHD finger protein 19)

Gene

• Entrez ID: 26147
• Gene name: PHD finger protein 19
• Gene symbol: PHF19
• Synonyms: MTF2L1, PCL3, TDRD19B
• Chromosome: 9
• Chromosome location: 9q33.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT002687	hsa-miR-124-3p	Microarray	15685193
MIRT016585	hsa-miR-193b-3p	Microarray	20304954
MIRT002687	hsa-miR-124-3p	Microarray	15685193
MIRT002687	hsa-miR-124-3p	Microarray	18668037
MIRT025582	hsa-miR-34a-5p	Sequencing	20371350
MIRT026902	hsa-miR-192-5p	Microarray	19074876
MIRT027228	hsa-miR-103a-3p	Sequencing	20371350
MIRT027908	hsa-miR-96-5p	Sequencing	20371350
MIRT032068	hsa-miR-16-5p	Sequencing	20371350
MIRT040639	hsa-miR-92b-3p	CLASH	23622248
MIRT655180	hsa-miR-4640-3p	HITS-CLIP	23824327
MIRT655179	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT471141	hsa-miR-1470	HITS-CLIP	23824327
MIRT471140	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT655178	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT655177	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT655176	hsa-miR-4469	HITS-CLIP	23824327
MIRT655175	hsa-miR-3166	HITS-CLIP	23824327
MIRT655174	hsa-miR-4771	HITS-CLIP	23824327
MIRT655173	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT655172	hsa-miR-1273h-3p	HITS-CLIP	23824327
MIRT655171	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT655170	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT655169	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT571829	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT571828	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT571827	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT571825	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT571826	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT032068	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT571824	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT571823	hsa-miR-548ac	PAR-CLIP	20371350
MIRT571822	hsa-miR-548bb-3p	PAR-CLIP	20371350
MIRT571821	hsa-miR-548d-3p	PAR-CLIP	20371350
MIRT571820	hsa-miR-548h-3p	PAR-CLIP	20371350
MIRT571819	hsa-miR-548z	PAR-CLIP	20371350
MIRT571818	hsa-miR-548ae-3p	PAR-CLIP	20371350
MIRT571817	hsa-miR-548ah-3p	PAR-CLIP	20371350
MIRT571815	hsa-miR-548aj-3p	PAR-CLIP	20371350
MIRT571816	hsa-miR-548am-3p	PAR-CLIP	20371350
MIRT571814	hsa-miR-548aq-3p	PAR-CLIP	20371350
MIRT571813	hsa-miR-548j-3p	PAR-CLIP	20371350
MIRT571812	hsa-miR-548x-3p	PAR-CLIP	20371350
MIRT571811	hsa-miR-548aa	PAR-CLIP	20371350
MIRT571810	hsa-miR-548ap-3p	PAR-CLIP	20371350
MIRT571809	hsa-miR-548t-3p	PAR-CLIP	20371350
MIRT571808	hsa-miR-548e-5p	PAR-CLIP	20371350
MIRT571807	hsa-miR-4477a	PAR-CLIP	20371350
MIRT506210	hsa-miR-449a	PAR-CLIP	23446348
MIRT025582	hsa-miR-34a-5p	PAR-CLIP	23446348
MIRT506209	hsa-miR-34c-5p	PAR-CLIP	23446348
MIRT506208	hsa-miR-449b-5p	PAR-CLIP	23446348
MIRT506207	hsa-miR-223-3p	PAR-CLIP	23446348
MIRT506206	hsa-miR-3974	PAR-CLIP	23446348
MIRT506205	hsa-miR-5700	PAR-CLIP	23446348
MIRT506204	hsa-miR-4715-5p	PAR-CLIP	23446348
MIRT506203	hsa-miR-3126-3p	PAR-CLIP	23446348
MIRT506202	hsa-miR-1298-3p	PAR-CLIP	23446348
MIRT506201	hsa-miR-4490	PAR-CLIP	23446348
MIRT506200	hsa-miR-4774-5p	PAR-CLIP	23446348
MIRT506199	hsa-miR-4660	PAR-CLIP	23446348
MIRT506198	hsa-miR-548au-3p	PAR-CLIP	23446348
MIRT506197	hsa-miR-1301-3p	PAR-CLIP	23446348
MIRT506196	hsa-miR-5047	PAR-CLIP	23446348
MIRT506195	hsa-miR-7150	PAR-CLIP	23446348
MIRT471146	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT471145	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT471144	hsa-miR-4781-3p	PAR-CLIP	23592263
MIRT471143	hsa-miR-1245b-3p	PAR-CLIP	23592263
MIRT471142	hsa-miR-488-5p	PAR-CLIP	23592263
MIRT471141	hsa-miR-1470	PAR-CLIP	23592263
MIRT471140	hsa-miR-4667-3p	PAR-CLIP	23592263
MIRT471139	hsa-miR-1827	PAR-CLIP	23592263
MIRT471138	hsa-miR-218-1-3p	PAR-CLIP	23592263
MIRT471137	hsa-miR-659-3p	PAR-CLIP	23592263
MIRT471136	hsa-miR-4796-3p	PAR-CLIP	23592263
MIRT471134	hsa-miR-3125	PAR-CLIP	23592263
MIRT471135	hsa-miR-3916	PAR-CLIP	23592263
MIRT471133	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT471132	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT471131	hsa-miR-6828-5p	PAR-CLIP	23592263
MIRT471130	hsa-miR-7974	PAR-CLIP	23592263
MIRT471129	hsa-miR-4656	PAR-CLIP	23592263
MIRT471128	hsa-miR-6829-5p	PAR-CLIP	23592263
MIRT471126	hsa-miR-4492	PAR-CLIP	23592263
MIRT471127	hsa-miR-4498	PAR-CLIP	23592263
MIRT471125	hsa-miR-5001-5p	PAR-CLIP	23592263
MIRT471124	hsa-miR-762	PAR-CLIP	23592263
MIRT471123	hsa-miR-4675	PAR-CLIP	23592263
MIRT471122	hsa-miR-4741	PAR-CLIP	23592263
MIRT471121	hsa-miR-363-5p	PAR-CLIP	23592263
MIRT471120	hsa-miR-6745	PAR-CLIP	23592263
MIRT471118	hsa-miR-6756-5p	PAR-CLIP	23592263
MIRT471119	hsa-miR-6766-5p	PAR-CLIP	23592263
MIRT471117	hsa-miR-1293	PAR-CLIP	23592263
MIRT471116	hsa-miR-4483	PAR-CLIP	23592263
MIRT471115	hsa-miR-541-3p	PAR-CLIP	23592263
MIRT471114	hsa-miR-654-5p	PAR-CLIP	23592263
MIRT471113	hsa-miR-4417	PAR-CLIP	23592263
MIRT471112	hsa-miR-6748-5p	PAR-CLIP	23592263
MIRT471110	hsa-miR-1587	PAR-CLIP	23592263
MIRT471111	hsa-miR-3620-5p	PAR-CLIP	23592263
MIRT439987	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT439987	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT571824	hsa-miR-15a-5p	Luciferase reporter assay, Western blotting, qRT-PCR	32312841
MIRT655180	hsa-miR-4640-3p	HITS-CLIP	23824327
MIRT655179	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT471141	hsa-miR-1470	HITS-CLIP	23824327
MIRT471140	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT655178	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT655177	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT655176	hsa-miR-4469	HITS-CLIP	23824327
MIRT655175	hsa-miR-3166	HITS-CLIP	23824327
MIRT655174	hsa-miR-4771	HITS-CLIP	23824327
MIRT655173	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT655172	hsa-miR-1273h-3p	HITS-CLIP	23824327
MIRT655171	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT655170	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT655169	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT571829	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT571828	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT571827	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT571825	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT571826	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT032068	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT571824	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT571823	hsa-miR-548ac	PAR-CLIP	20371350
MIRT571822	hsa-miR-548bb-3p	PAR-CLIP	20371350
MIRT571821	hsa-miR-548d-3p	PAR-CLIP	20371350
MIRT571820	hsa-miR-548h-3p	PAR-CLIP	20371350
MIRT571819	hsa-miR-548z	PAR-CLIP	20371350
MIRT571818	hsa-miR-548ae-3p	PAR-CLIP	20371350
MIRT571817	hsa-miR-548ah-3p	PAR-CLIP	20371350
MIRT571815	hsa-miR-548aj-3p	PAR-CLIP	20371350
MIRT571816	hsa-miR-548am-3p	PAR-CLIP	20371350
MIRT571814	hsa-miR-548aq-3p	PAR-CLIP	20371350
MIRT571813	hsa-miR-548j-3p	PAR-CLIP	20371350
MIRT571812	hsa-miR-548x-3p	PAR-CLIP	20371350
MIRT571811	hsa-miR-548aa	PAR-CLIP	20371350
MIRT571810	hsa-miR-548ap-3p	PAR-CLIP	20371350
MIRT571809	hsa-miR-548t-3p	PAR-CLIP	20371350
MIRT571808	hsa-miR-548e-5p	PAR-CLIP	20371350
MIRT571807	hsa-miR-4477a	PAR-CLIP	20371350
MIRT506210	hsa-miR-449a	PAR-CLIP	23446348
MIRT025582	hsa-miR-34a-5p	PAR-CLIP	23446348
MIRT506209	hsa-miR-34c-5p	PAR-CLIP	23446348
MIRT506208	hsa-miR-449b-5p	PAR-CLIP	23446348
MIRT506207	hsa-miR-223-3p	PAR-CLIP	23446348
MIRT506206	hsa-miR-3974	PAR-CLIP	23446348
MIRT506205	hsa-miR-5700	PAR-CLIP	23446348
MIRT506204	hsa-miR-4715-5p	PAR-CLIP	23446348
MIRT506203	hsa-miR-3126-3p	PAR-CLIP	23446348
MIRT506202	hsa-miR-1298-3p	PAR-CLIP	23446348
MIRT506201	hsa-miR-4490	PAR-CLIP	23446348
MIRT506200	hsa-miR-4774-5p	PAR-CLIP	23446348
MIRT506199	hsa-miR-4660	PAR-CLIP	23446348
MIRT506198	hsa-miR-548au-3p	PAR-CLIP	23446348
MIRT506197	hsa-miR-1301-3p	PAR-CLIP	23446348
MIRT506196	hsa-miR-5047	PAR-CLIP	23446348
MIRT506195	hsa-miR-7150	PAR-CLIP	23446348
MIRT471146	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT471145	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT471144	hsa-miR-4781-3p	PAR-CLIP	23592263
MIRT471143	hsa-miR-1245b-3p	PAR-CLIP	23592263
MIRT471142	hsa-miR-488-5p	PAR-CLIP	23592263
MIRT471141	hsa-miR-1470	PAR-CLIP	23592263
MIRT471140	hsa-miR-4667-3p	PAR-CLIP	23592263
MIRT471139	hsa-miR-1827	PAR-CLIP	23592263
MIRT471138	hsa-miR-218-1-3p	PAR-CLIP	23592263
MIRT471137	hsa-miR-659-3p	PAR-CLIP	23592263
MIRT471136	hsa-miR-4796-3p	PAR-CLIP	23592263
MIRT471134	hsa-miR-3125	PAR-CLIP	23592263
MIRT471135	hsa-miR-3916	PAR-CLIP	23592263
MIRT471133	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT471132	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT471131	hsa-miR-6828-5p	PAR-CLIP	23592263
MIRT471130	hsa-miR-7974	PAR-CLIP	23592263
MIRT471129	hsa-miR-4656	PAR-CLIP	23592263
MIRT471128	hsa-miR-6829-5p	PAR-CLIP	23592263
MIRT471126	hsa-miR-4492	PAR-CLIP	23592263
MIRT471127	hsa-miR-4498	PAR-CLIP	23592263
MIRT471125	hsa-miR-5001-5p	PAR-CLIP	23592263
MIRT471124	hsa-miR-762	PAR-CLIP	23592263
MIRT471123	hsa-miR-4675	PAR-CLIP	23592263
MIRT471122	hsa-miR-4741	PAR-CLIP	23592263
MIRT471121	hsa-miR-363-5p	PAR-CLIP	23592263
MIRT471120	hsa-miR-6745	PAR-CLIP	23592263
MIRT471118	hsa-miR-6756-5p	PAR-CLIP	23592263
MIRT471119	hsa-miR-6766-5p	PAR-CLIP	23592263
MIRT471117	hsa-miR-1293	PAR-CLIP	23592263
MIRT471116	hsa-miR-4483	PAR-CLIP	23592263
MIRT471115	hsa-miR-541-3p	PAR-CLIP	23592263
MIRT471114	hsa-miR-654-5p	PAR-CLIP	23592263
MIRT471113	hsa-miR-4417	PAR-CLIP	23592263
MIRT471112	hsa-miR-6748-5p	PAR-CLIP	23592263
MIRT471110	hsa-miR-1587	PAR-CLIP	23592263
MIRT471111	hsa-miR-3620-5p	PAR-CLIP	23592263
MIRT1230580	hsa-miR-103a	CLIP-seq
MIRT1230581	hsa-miR-107	CLIP-seq
MIRT1230582	hsa-miR-1237	CLIP-seq
MIRT1230583	hsa-miR-1291	CLIP-seq
MIRT1230584	hsa-miR-1301	CLIP-seq
MIRT1230585	hsa-miR-1304	CLIP-seq
MIRT1230586	hsa-miR-1321	CLIP-seq
MIRT1230587	hsa-miR-138	CLIP-seq
MIRT1230588	hsa-miR-193a-5p	CLIP-seq
MIRT1230589	hsa-miR-203	CLIP-seq
MIRT1230590	hsa-miR-204	CLIP-seq
MIRT1230591	hsa-miR-211	CLIP-seq
MIRT1230592	hsa-miR-223	CLIP-seq
MIRT1230593	hsa-miR-2467-3p	CLIP-seq
MIRT1230594	hsa-miR-296-5p	CLIP-seq
MIRT1230595	hsa-miR-3065-3p	CLIP-seq
MIRT1230596	hsa-miR-3126-5p	CLIP-seq
MIRT1230597	hsa-miR-3150a-3p	CLIP-seq
MIRT1230598	hsa-miR-3151	CLIP-seq
MIRT1230599	hsa-miR-3153	CLIP-seq
MIRT1230600	hsa-miR-3158-3p	CLIP-seq
MIRT1230601	hsa-miR-3175	CLIP-seq
MIRT1230602	hsa-miR-3184	CLIP-seq
MIRT1230603	hsa-miR-342-5p	CLIP-seq
MIRT1230604	hsa-miR-34a	CLIP-seq
MIRT1230605	hsa-miR-3612	CLIP-seq
MIRT1230606	hsa-miR-3678-3p	CLIP-seq
MIRT1230607	hsa-miR-3688-5p	CLIP-seq
MIRT1230608	hsa-miR-3689a-3p	CLIP-seq
MIRT1230609	hsa-miR-3689c	CLIP-seq
MIRT1230610	hsa-miR-3919	CLIP-seq
MIRT1230611	hsa-miR-3922-5p	CLIP-seq
MIRT1230612	hsa-miR-3925-5p	CLIP-seq
MIRT1230613	hsa-miR-423-5p	CLIP-seq
MIRT1230614	hsa-miR-4283	CLIP-seq
MIRT1230615	hsa-miR-4297	CLIP-seq
MIRT1230616	hsa-miR-4303	CLIP-seq
MIRT1230617	hsa-miR-4308	CLIP-seq
MIRT1230618	hsa-miR-4316	CLIP-seq
MIRT1230619	hsa-miR-4419a	CLIP-seq
MIRT1230620	hsa-miR-4447	CLIP-seq
MIRT1230621	hsa-miR-4450	CLIP-seq
MIRT1230622	hsa-miR-4472	CLIP-seq
MIRT1230623	hsa-miR-4489	CLIP-seq
MIRT1230624	hsa-miR-449b	CLIP-seq
MIRT1230625	hsa-miR-4510	CLIP-seq
MIRT1230626	hsa-miR-4649-3p	CLIP-seq
MIRT1230627	hsa-miR-4649-5p	CLIP-seq
MIRT1230628	hsa-miR-4651	CLIP-seq
MIRT1230629	hsa-miR-4664-5p	CLIP-seq
MIRT1230630	hsa-miR-4667-5p	CLIP-seq
MIRT1230631	hsa-miR-4700-5p	CLIP-seq
MIRT1230632	hsa-miR-4710	CLIP-seq
MIRT1230633	hsa-miR-4728-5p	CLIP-seq
MIRT1230634	hsa-miR-4731-5p	CLIP-seq
MIRT1230635	hsa-miR-4739	CLIP-seq
MIRT1230636	hsa-miR-4756-5p	CLIP-seq
MIRT1230637	hsa-miR-4773	CLIP-seq
MIRT1230638	hsa-miR-491-5p	CLIP-seq
MIRT1230639	hsa-miR-541	CLIP-seq
MIRT1230640	hsa-miR-548q	CLIP-seq
MIRT1230641	hsa-miR-608	CLIP-seq
MIRT1230642	hsa-miR-623	CLIP-seq
MIRT1230643	hsa-miR-637	CLIP-seq
MIRT1230644	hsa-miR-646	CLIP-seq
MIRT1230645	hsa-miR-650	CLIP-seq
MIRT1230646	hsa-miR-765	CLIP-seq
MIRT1230647	hsa-miR-885-3p	CLIP-seq
MIRT1230648	hsa-miR-939	CLIP-seq
MIRT2067655	hsa-miR-1193	CLIP-seq
MIRT2067656	hsa-miR-1231	CLIP-seq
MIRT2067657	hsa-miR-23a	CLIP-seq
MIRT2067658	hsa-miR-23b	CLIP-seq
MIRT2067659	hsa-miR-23c	CLIP-seq
MIRT2067660	hsa-miR-346	CLIP-seq
MIRT2067661	hsa-miR-3691-5p	CLIP-seq
MIRT2067662	hsa-miR-370	CLIP-seq
MIRT2067663	hsa-miR-4288	CLIP-seq
MIRT2067664	hsa-miR-4491	CLIP-seq
MIRT2067665	hsa-miR-4643	CLIP-seq
MIRT2067666	hsa-miR-4657	CLIP-seq
MIRT1230630	hsa-miR-4667-5p	CLIP-seq
MIRT1230631	hsa-miR-4700-5p	CLIP-seq
MIRT2067667	hsa-miR-4752	CLIP-seq
MIRT2067668	hsa-miR-493	CLIP-seq
MIRT2067669	hsa-miR-632	CLIP-seq
MIRT2067670	hsa-miR-644	CLIP-seq
MIRT2067655	hsa-miR-1193	CLIP-seq
MIRT2295061	hsa-miR-147b	CLIP-seq
MIRT2295062	hsa-miR-15a	CLIP-seq
MIRT2295063	hsa-miR-15b	CLIP-seq
MIRT2295064	hsa-miR-16	CLIP-seq
MIRT2295065	hsa-miR-195	CLIP-seq
MIRT2295066	hsa-miR-210	CLIP-seq
MIRT2295067	hsa-miR-3192	CLIP-seq
MIRT2295068	hsa-miR-3650	CLIP-seq
MIRT2067661	hsa-miR-3691-5p	CLIP-seq
MIRT2295069	hsa-miR-424	CLIP-seq
MIRT1230617	hsa-miR-4308	CLIP-seq
MIRT2295070	hsa-miR-4455	CLIP-seq
MIRT2295071	hsa-miR-4481	CLIP-seq
MIRT2067664	hsa-miR-4491	CLIP-seq
MIRT2067665	hsa-miR-4643	CLIP-seq
MIRT2067666	hsa-miR-4657	CLIP-seq
MIRT2295072	hsa-miR-4745-5p	CLIP-seq
MIRT2067667	hsa-miR-4752	CLIP-seq
MIRT2295073	hsa-miR-497	CLIP-seq
MIRT2295074	hsa-miR-532-3p	CLIP-seq
MIRT2295075	hsa-miR-609	CLIP-seq
MIRT2295076	hsa-miR-671-5p	CLIP-seq
MIRT2067656	hsa-miR-1231	CLIP-seq
MIRT2456358	hsa-miR-1224-3p	CLIP-seq
MIRT2456359	hsa-miR-1254	CLIP-seq
MIRT2456360	hsa-miR-1260	CLIP-seq
MIRT2456361	hsa-miR-1260b	CLIP-seq
MIRT2456362	hsa-miR-1280	CLIP-seq
MIRT2456363	hsa-miR-1299	CLIP-seq
MIRT2456364	hsa-miR-150	CLIP-seq
MIRT2456365	hsa-miR-3116	CLIP-seq
MIRT2456366	hsa-miR-3978	CLIP-seq
MIRT2456367	hsa-miR-4254	CLIP-seq
MIRT2456368	hsa-miR-4434	CLIP-seq
MIRT2456369	hsa-miR-4516	CLIP-seq
MIRT2456370	hsa-miR-4531	CLIP-seq
MIRT2456371	hsa-miR-4650-5p	CLIP-seq
MIRT2456372	hsa-miR-4690-5p	CLIP-seq
MIRT2456373	hsa-miR-4713-5p	CLIP-seq
MIRT2295074	hsa-miR-532-3p	CLIP-seq
MIRT2456374	hsa-miR-875-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IBA	21873635
GO:0003682	Function	Chromatin binding	IBA	21873635
GO:0005515	Function	Protein binding	IPI	23104054, 23160351, 23455924, 32296183, 32814053
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005654	Component	Nucleoplasm	TAS
GO:0006325	Process	Chromatin organization	IBA	21873635
GO:0006355	Process	Regulation of transcription, DNA-templated	IBA	21873635
GO:0035064	Function	Methylated histone binding	IBA	21873635
GO:0035064	Function	Methylated histone binding	IDA	23104054, 23160351, 23273982
GO:0035098	Component	ESC/E(Z) complex	IBA	21873635
GO:0035098	Component	ESC/E(Z) complex	IDA	23104054
GO:0045814	Process	Negative regulation of gene expression, epigenetic	TAS
GO:0046872	Function	Metal ion binding	IEA
GO:0061087	Process	Positive regulation of histone H3-K27 methylation	IMP	23104054

Other IDs

• MIM: 609740
• HGNC: 24566
• e!Ensembl: ENSG00000119403

Protein

• UniProt ID: Q5T6S3
• Protein name: PHD finger protein 19 (Polycomb-like protein 3) (hPCL3)
• Protein function: Polycomb group (PcG) protein that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex, thus enhancing PRC2 H3K27me3 methylation activity (PubMed:15563832, PubMed:18691976, PubMed:23104054, PubMed:2316
• PDB: 2E5Q, 4BD3, 6NQ3, 6WAU
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF18104	Tudor_2	43 → 78	Jumonji domain-containing protein 2A Tudor domain	Domain
  PF00628	PHD	98 → 151	PHD-finger	Domain
  PF14061	Mtf2_C	531 → 578	Polycomb-like MTF2 factor 2	Domain

• Sequence:

  MENRALDPGTRDSYGATSHLPNKGALAKVKNNFKDLMSKLTEGQYVLCRWTDGLYYLGKI
  KRVSSSKQSCLVTFEDNSKYWVLWKDIQHAGVPGEEPKCNICLGKTSGPLNEILICGKCG
  LGYHQQCHIPIAGSADQPLLTPWFCRRCIFALAVRKGGALKKGAIARTLQAVKMVLSYQP
  EELEWDSPHRTNQQQCYCYCGGPGEWYLRMLQCYRCRQWFHEACTQCLNEPMMFGDRFYL
  FFCSVCNQGPEYIERLPLRWVDVVHLALYNLGVQSKKKYFDFEEILAFVNHHWELLQLGK
  LTSTPVTDRGPHLLNALNSYKSRFLCGKEIKKKKCIFRLRIRVPPNPPGKLLPDKGLLPN
  ENSASSELRKRGKSKPGLLPHEFQQQKRRVYRRKRSKFLLEDAIPSSDFTSAWSTNHHLA
  SIFDFTLDEIQSLKSASSGQTFFSDVDSTDAASTSGSASTSLSYDSRWTVGSRKRKLAAK
  AYMPLRAKRWAAELDGRCPSDSSAEGASVPERPDEGIDSHTFESISEDDSSLSHLKSSIT
  NYFGAAGRLACGEKYQVLARRVTPEGKVQYLVEWEGTTPY

• Sequence length: 580

Pathways

KEGG:

Polycomb repressive complex

Reactome:

PRC2 methylates histones and DNA

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Asthma	Asthma	rs324981, rs121912630, rs150116809, rs4950928, rs708494, rs1581842283	21907864
Autoimmune diseases	Autoimmune Diseases	rs41285370, rs869025224	21383967
Rheumatoid arthritis	Rheumatoid Arthritis	rs3766379, rs3792876, rs2071592, rs3087456, rs587776843, rs1566328963, rs2240340, rs1557787212	24782177, 17804836, 24390342, 30423114, 19503088

Unknown
Disease name	Disease term	dbSNP ID	References
Eczema	Eczema		30595370
Immune system diseases	Immune System Diseases		21383967