Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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26136 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Testin LIM domain protein |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
TES |
SynonymsGene synonyms aliases
|
TESS, TESS-2 |
ChromosomeChromosome number
|
7 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
7q31.2 |
SummarySummary of gene provided in NCBI Entrez Gene.
|
Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli ce |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
|
UniProt ID |
Q9UGI8 |
Protein name |
Testin (TESS) |
Protein function |
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor. Inhibits tumor cell growth. {ECO:000 |
PDB |
2IYB
,
2XQN
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF06297 |
PET |
109 → 193 |
PET Domain |
Domain |
PF00412 |
LIM |
236 → 297 |
LIM domain |
Domain |
PF00412 |
LIM |
301 → 357 |
LIM domain |
Domain |
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Sequence |
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Sequence length |
421 |
Interactions |
View interactions |
Associated diseases
|
|
Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Giant cell glioblastoma |
Giant Cell Glioblastoma |
|
16909125 |
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