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CCDC69 (coiled-coil domain containing 69)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
26112
Gene nameGene Name - the full gene name approved by the HGNC.
Coiled-coil domain containing 69
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
CCDC69
SynonymsGene synonyms aliases
-
ChromosomeChromosome number
5
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
5q33.1
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT018220 hsa-miR-335-5p Microarray 18185580
MIRT646681 hsa-miR-892a HITS-CLIP 23824327
MIRT646680 hsa-miR-6858-3p HITS-CLIP 23824327
MIRT646679 hsa-miR-4676-5p HITS-CLIP 23824327
MIRT646678 hsa-miR-575 HITS-CLIP 23824327
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005634 Component Nucleus IBA 21873635
GO:0005737 Component Cytoplasm IBA 21873635
GO:0008017 Function Microtubule binding IBA 21873635
GO:0030496 Component Midbody IEA
GO:0051233 Component Spindle midzone IDA 20962590
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID A6NI79
Protein name Coiled-coil domain-containing protein 69
Protein function May act as a scaffold to regulate the recruitment and assembly of spindle midzone components. Required for the localization of AURKB and PLK1 to the spindle midzone.
Family and domains
Sequence
MGCRHSRLSSCKPPKKKRQEPEPEQPPRPEPHELGPLNGDTAITVQLCASEEAERHQKDI
TRILQQHEEEKKKWAQQVEKERELELRDRLDEQQRVLEGKNEEALQVLRASYEQEKEALT
HSFREASSTQQETIDRLTSQLEAFQAKMKRVEESILSRNYKKHIQDYGSPSQFWEQELES
LHFVIEMKNERIHELDRRLILMETVKEKNLILEEKITTLQQENEDLHVRSRNQVVLSRQL
SEDLLLTREALEKEVQLRRQLQQEKEELLYRVLGANASPAFPLAPVTPTEVSFLAT
Sequence length 296
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Chronic obstructive pulmonary disease Chronic Obstructive Airway Disease rs2227956, rs1008438, rs1043618, rs562047, rs1061581, rs2763979, rs6457452, rs13147758, rs1828591, rs13118928 30804561

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