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IPCEF1 (interaction protein for cytohesin exchange factors 1)

Gene

26034

Interaction protein for cytohesin exchange factors 1

IPCEF1

PIP3-E, PIP3E

6q25.2

Show/Hide all(238)

miRTarBase ID	miRNA	Experiments	Reference
MIRT022415	hsa-miR-124-3p	Microarray	18668037
MIRT052329	hsa-let-7b-5p	CLASH	23622248
MIRT047560	hsa-miR-10a-5p	CLASH	23622248
MIRT047416	hsa-miR-10b-5p	CLASH	23622248
MIRT667868	hsa-miR-34b-3p	HITS-CLIP	23824327
MIRT667867	hsa-miR-6753-5p	HITS-CLIP	23824327
MIRT667866	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT667865	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT667864	hsa-miR-940	HITS-CLIP	23824327
MIRT667863	hsa-miR-3929	HITS-CLIP	23824327
MIRT667862	hsa-miR-4419b	HITS-CLIP	23824327
MIRT667861	hsa-miR-4478	HITS-CLIP	23824327
MIRT667860	hsa-miR-1321	HITS-CLIP	23824327
MIRT667859	hsa-miR-4739	HITS-CLIP	23824327
MIRT667858	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT667857	hsa-miR-5690	HITS-CLIP	23824327
MIRT667856	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT667855	hsa-miR-4270	HITS-CLIP	23824327
MIRT667854	hsa-miR-4441	HITS-CLIP	23824327
MIRT667853	hsa-miR-6754-5p	HITS-CLIP	23824327
MIRT667852	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT667851	hsa-miR-6746-5p	HITS-CLIP	23824327
MIRT667850	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT667849	hsa-miR-676-5p	HITS-CLIP	23824327
MIRT667848	hsa-miR-1827	HITS-CLIP	23824327
MIRT667847	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT667846	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT667845	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT667844	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT667843	hsa-miR-3612	HITS-CLIP	23824327
MIRT667842	hsa-miR-650	HITS-CLIP	23824327
MIRT667841	hsa-miR-6771-5p	HITS-CLIP	23824327
MIRT667840	hsa-miR-665	HITS-CLIP	23824327
MIRT623612	hsa-miR-5582-5p	HITS-CLIP	23824327
MIRT623611	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT623610	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT623609	hsa-miR-8064	HITS-CLIP	23824327
MIRT623608	hsa-miR-664b-5p	HITS-CLIP	23824327
MIRT623607	hsa-miR-623	HITS-CLIP	23824327
MIRT623606	hsa-miR-4674	HITS-CLIP	23824327
MIRT623605	hsa-miR-1587	HITS-CLIP	23824327
MIRT623603	hsa-miR-3620-5p	HITS-CLIP	23824327
MIRT623604	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT623602	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT623601	hsa-miR-521	HITS-CLIP	23824327
MIRT667868	hsa-miR-34b-3p	HITS-CLIP	23824327
MIRT667867	hsa-miR-6753-5p	HITS-CLIP	23824327
MIRT667866	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT667865	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT667864	hsa-miR-940	HITS-CLIP	23824327
MIRT667863	hsa-miR-3929	HITS-CLIP	23824327
MIRT667862	hsa-miR-4419b	HITS-CLIP	23824327
MIRT667861	hsa-miR-4478	HITS-CLIP	23824327
MIRT667860	hsa-miR-1321	HITS-CLIP	23824327
MIRT667859	hsa-miR-4739	HITS-CLIP	23824327
MIRT667858	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT667857	hsa-miR-5690	HITS-CLIP	23824327
MIRT667856	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT667855	hsa-miR-4270	HITS-CLIP	23824327
MIRT667854	hsa-miR-4441	HITS-CLIP	23824327
MIRT667853	hsa-miR-6754-5p	HITS-CLIP	23824327
MIRT667852	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT667851	hsa-miR-6746-5p	HITS-CLIP	23824327
MIRT667850	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT667849	hsa-miR-676-5p	HITS-CLIP	23824327
MIRT667848	hsa-miR-1827	HITS-CLIP	23824327
MIRT667847	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT667846	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT667845	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT667844	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT667843	hsa-miR-3612	HITS-CLIP	23824327
MIRT667842	hsa-miR-650	HITS-CLIP	23824327
MIRT667841	hsa-miR-6771-5p	HITS-CLIP	23824327
MIRT667840	hsa-miR-665	HITS-CLIP	23824327
MIRT623612	hsa-miR-5582-5p	HITS-CLIP	23824327
MIRT623611	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT623610	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT623609	hsa-miR-8064	HITS-CLIP	23824327
MIRT623608	hsa-miR-664b-5p	HITS-CLIP	23824327
MIRT623607	hsa-miR-623	HITS-CLIP	23824327
MIRT623606	hsa-miR-4674	HITS-CLIP	23824327
MIRT623605	hsa-miR-1587	HITS-CLIP	23824327
MIRT623603	hsa-miR-3620-5p	HITS-CLIP	23824327
MIRT623604	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT623602	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT623601	hsa-miR-521	HITS-CLIP	23824327
MIRT1068445	hsa-miR-1228	CLIP-seq
MIRT1068446	hsa-miR-1279	CLIP-seq
MIRT1068447	hsa-miR-1281	CLIP-seq
MIRT1068448	hsa-miR-1285	CLIP-seq
MIRT1068449	hsa-miR-150	CLIP-seq
MIRT1068450	hsa-miR-205	CLIP-seq
MIRT1068451	hsa-miR-24	CLIP-seq
MIRT1068452	hsa-miR-2467-3p	CLIP-seq
MIRT1068453	hsa-miR-3120-5p	CLIP-seq
MIRT1068454	hsa-miR-3187-5p	CLIP-seq
MIRT1068455	hsa-miR-3192	CLIP-seq
MIRT1068456	hsa-miR-326	CLIP-seq
MIRT1068457	hsa-miR-330-5p	CLIP-seq
MIRT1068458	hsa-miR-342-3p	CLIP-seq
MIRT1068459	hsa-miR-3613-5p	CLIP-seq
MIRT1068460	hsa-miR-3664-5p	CLIP-seq
MIRT1068461	hsa-miR-3689a-3p	CLIP-seq
MIRT1068462	hsa-miR-3689c	CLIP-seq
MIRT1068463	hsa-miR-3934	CLIP-seq
MIRT1068464	hsa-miR-4261	CLIP-seq
MIRT1068465	hsa-miR-4284	CLIP-seq
MIRT1068466	hsa-miR-4314	CLIP-seq
MIRT1068467	hsa-miR-4421	CLIP-seq
MIRT1068468	hsa-miR-4432	CLIP-seq
MIRT1068469	hsa-miR-4496	CLIP-seq
MIRT1068470	hsa-miR-451b	CLIP-seq
MIRT1068471	hsa-miR-4522	CLIP-seq
MIRT1068472	hsa-miR-4646-5p	CLIP-seq
MIRT1068473	hsa-miR-4665-3p	CLIP-seq
MIRT1068474	hsa-miR-4684-5p	CLIP-seq
MIRT1068475	hsa-miR-4696	CLIP-seq
MIRT1068476	hsa-miR-4713-5p	CLIP-seq
MIRT1068477	hsa-miR-4728-5p	CLIP-seq
MIRT1068478	hsa-miR-4753-3p	CLIP-seq
MIRT1068479	hsa-miR-4768-5p	CLIP-seq
MIRT1068480	hsa-miR-4796-5p	CLIP-seq
MIRT1068481	hsa-miR-483-3p	CLIP-seq
MIRT1068482	hsa-miR-494	CLIP-seq
MIRT1068483	hsa-miR-532-3p	CLIP-seq
MIRT1068484	hsa-miR-612	CLIP-seq
MIRT1068485	hsa-miR-661	CLIP-seq
MIRT1068448	hsa-miR-1285	CLIP-seq
MIRT1068486	hsa-miR-204	CLIP-seq
MIRT1068487	hsa-miR-211	CLIP-seq
MIRT1068488	hsa-miR-2277-3p	CLIP-seq
MIRT1068452	hsa-miR-2467-3p	CLIP-seq
MIRT1068489	hsa-miR-3122	CLIP-seq
MIRT1068454	hsa-miR-3187-5p	CLIP-seq
MIRT1068490	hsa-miR-3613-3p	CLIP-seq
MIRT1068491	hsa-miR-3622a-3p	CLIP-seq
MIRT1068492	hsa-miR-3622b-3p	CLIP-seq
MIRT1068493	hsa-miR-371b-5p	CLIP-seq
MIRT1068494	hsa-miR-377	CLIP-seq
MIRT1068495	hsa-miR-3913-5p	CLIP-seq
MIRT1068496	hsa-miR-3923	CLIP-seq
MIRT1068497	hsa-miR-3926	CLIP-seq
MIRT1068498	hsa-miR-4257	CLIP-seq
MIRT1068499	hsa-miR-4328	CLIP-seq
MIRT1068500	hsa-miR-4433	CLIP-seq
MIRT1068501	hsa-miR-4446-5p	CLIP-seq
MIRT1068502	hsa-miR-4459	CLIP-seq
MIRT1068503	hsa-miR-4640-5p	CLIP-seq
MIRT1068504	hsa-miR-4704-5p	CLIP-seq
MIRT1068505	hsa-miR-4726-5p	CLIP-seq
MIRT1068506	hsa-miR-4731-5p	CLIP-seq
MIRT1068507	hsa-miR-4778-3p	CLIP-seq
MIRT1068508	hsa-miR-514	CLIP-seq
MIRT1068509	hsa-miR-514b-3p	CLIP-seq
MIRT1068510	hsa-miR-544b	CLIP-seq
MIRT1068511	hsa-miR-587	CLIP-seq
MIRT1068484	hsa-miR-612	CLIP-seq
MIRT1068512	hsa-miR-628-3p	CLIP-seq
MIRT1068485	hsa-miR-661	CLIP-seq
MIRT2248780	hsa-miR-1179	CLIP-seq
MIRT2248781	hsa-miR-4324	CLIP-seq
MIRT1068510	hsa-miR-544b	CLIP-seq
MIRT2451896	hsa-miR-3163	CLIP-seq
MIRT2451897	hsa-miR-3675-5p	CLIP-seq
MIRT2451898	hsa-miR-4656	CLIP-seq
MIRT1068474	hsa-miR-4684-5p	CLIP-seq
MIRT1068477	hsa-miR-4728-5p	CLIP-seq
MIRT2451899	hsa-miR-486-3p	CLIP-seq
MIRT2451900	hsa-miR-548c-3p	CLIP-seq
MIRT2451901	hsa-miR-585	CLIP-seq
MIRT2451902	hsa-miR-885-3p	CLIP-seq
MIRT2451897	hsa-miR-3675-5p	CLIP-seq
MIRT2451898	hsa-miR-4656	CLIP-seq
MIRT1068477	hsa-miR-4728-5p	CLIP-seq
MIRT2451899	hsa-miR-486-3p	CLIP-seq
MIRT2451902	hsa-miR-885-3p	CLIP-seq
MIRT1068445	hsa-miR-1228	CLIP-seq
MIRT1068448	hsa-miR-1285	CLIP-seq
MIRT2552526	hsa-miR-2114	CLIP-seq
MIRT1068452	hsa-miR-2467-3p	CLIP-seq
MIRT1068453	hsa-miR-3120-5p	CLIP-seq
MIRT2451896	hsa-miR-3163	CLIP-seq
MIRT1068454	hsa-miR-3187-5p	CLIP-seq
MIRT1068455	hsa-miR-3192	CLIP-seq
MIRT1068456	hsa-miR-326	CLIP-seq
MIRT1068457	hsa-miR-330-5p	CLIP-seq
MIRT1068491	hsa-miR-3622a-3p	CLIP-seq
MIRT1068492	hsa-miR-3622b-3p	CLIP-seq
MIRT1068460	hsa-miR-3664-5p	CLIP-seq
MIRT1068461	hsa-miR-3689a-3p	CLIP-seq
MIRT1068462	hsa-miR-3689c	CLIP-seq
MIRT1068494	hsa-miR-377	CLIP-seq
MIRT2552527	hsa-miR-3924	CLIP-seq
MIRT2552528	hsa-miR-4252	CLIP-seq
MIRT1068466	hsa-miR-4314	CLIP-seq
MIRT1068468	hsa-miR-4432	CLIP-seq
MIRT1068500	hsa-miR-4433	CLIP-seq
MIRT1068502	hsa-miR-4459	CLIP-seq
MIRT2552529	hsa-miR-4514	CLIP-seq
MIRT1068470	hsa-miR-451b	CLIP-seq
MIRT1068471	hsa-miR-4522	CLIP-seq
MIRT1068472	hsa-miR-4646-5p	CLIP-seq
MIRT1068474	hsa-miR-4684-5p	CLIP-seq
MIRT2552530	hsa-miR-4692	CLIP-seq
MIRT1068475	hsa-miR-4696	CLIP-seq
MIRT1068477	hsa-miR-4728-5p	CLIP-seq
MIRT2552531	hsa-miR-4793-3p	CLIP-seq
MIRT2552532	hsa-miR-508-5p	CLIP-seq
MIRT1068510	hsa-miR-544b	CLIP-seq
MIRT2451900	hsa-miR-548c-3p	CLIP-seq
MIRT2552533	hsa-miR-561	CLIP-seq
MIRT2451901	hsa-miR-585	CLIP-seq
MIRT1068484	hsa-miR-612	CLIP-seq
MIRT2552534	hsa-miR-633	CLIP-seq
MIRT1068485	hsa-miR-661	CLIP-seq
MIRT2552535	hsa-miR-766	CLIP-seq
MIRT2682868	hsa-miR-1227	CLIP-seq
MIRT1068448	hsa-miR-1285	CLIP-seq
MIRT2552526	hsa-miR-2114	CLIP-seq
MIRT1068453	hsa-miR-3120-5p	CLIP-seq
MIRT2451896	hsa-miR-3163	CLIP-seq
MIRT1068454	hsa-miR-3187-5p	CLIP-seq
MIRT1068460	hsa-miR-3664-5p	CLIP-seq
MIRT2552528	hsa-miR-4252	CLIP-seq
MIRT1068468	hsa-miR-4432	CLIP-seq
MIRT1068470	hsa-miR-451b	CLIP-seq
MIRT1068471	hsa-miR-4522	CLIP-seq
MIRT1068474	hsa-miR-4684-5p	CLIP-seq
MIRT1068475	hsa-miR-4696	CLIP-seq
MIRT2552531	hsa-miR-4793-3p	CLIP-seq
MIRT2552532	hsa-miR-508-5p	CLIP-seq
MIRT2451900	hsa-miR-548c-3p	CLIP-seq
MIRT2552533	hsa-miR-561	CLIP-seq
MIRT2451901	hsa-miR-585	CLIP-seq
MIRT1068484	hsa-miR-612	CLIP-seq
MIRT2552534	hsa-miR-633	CLIP-seq
MIRT1068485	hsa-miR-661	CLIP-seq
MIRT2552535	hsa-miR-766	CLIP-seq

Show/Hide all(9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004601	Function	Peroxidase activity	ISS	11320098
GO:0005344	Function	Oxygen carrier activity	NAS	11919282
GO:0005515	Function	Protein binding	IPI	22085542, 32296183
GO:0005829	Component	Cytosol	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0006979	Process	Response to oxidative stress	ISS	11320098
GO:0015671	Process	Oxygen transport	NAS	11919282
GO:0019904	Function	Protein domain specific binding	IEA
GO:0098869	Process	Cellular oxidant detoxification	IEA

MIM	HGNC	e!Ensembl
619948	21204	ENSG00000074706

Protein

UniProt ID

Q8WWN9

Protein name

Interactor protein for cytohesin exchange factors 1 (Phosphoinositide-binding protein PIP3-E)

Protein function

Enhances the promotion of guanine-nucleotide exchange by PSCD2 on ARF6 in a concentration-dependent manner.

PDB

5MR1

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00169	PH	42 → 139	PH domain	Domain

Sequence

MTSYMAIDGSALVPLRQKPRRKTQGFLTMSRRRISCKDLGHADCQGWLYKKKEKGSFLSN
KWKKFWVILKGSSLYWYSNQMAEKADGFVNLPDFTVERASECKKKHAFKISHPQIKTFYF
AAENVQEMNVWLNKLGSAVIHQESTTKDEECYSESEQEDPEIAAETPPPPHASQTQSLTA
QQASSSSPSLSGTSYSFSSLENTVKTPSSFPSSLSKERQSLPDTVNSLSAAEDEGQPITF
AVQVHSPVPSEAGIHKALENSFVTSESGFLNSLSSDDTSSLSSNHDHLTVPDKPAGSKIM
DKEETKVSEDDEMEKLYKSLEQASLSPLGDRRPSTKKELRKSFVKRCKNPSINEKLHKIR
TLNSTLKCKEHDLAMINQLLDDPKLTARKYREWKVMNTLLIQDIYQQQRASPAPDDTDDT
PQELKKSPSSPSVENSI

Sequence length

437

Interactions

View interactions

Associated diseases

Show/Hide Causal Diseases (1)

Causal
Disease name	Disease term	dbSNP ID	References
Dermatitis	Dermatitis, Allergic Contact	rs61816761, rs150597413, rs138726443, rs201356558, rs149484917, rs372754256, rs747301529, rs567795279, rs745915174	17374397

Show/Hide Unknown Diseases (2)

Unknown
Disease name	Disease term	dbSNP ID	References
Lymphocytic leukemia	Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma		24292274
Lymphoid leukemia	Lymphoid leukemia		24292274

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