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MOB4 (MOB family member 4, phocein)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
25843
Gene nameGene Name - the full gene name approved by the HGNC.
MOB family member 4, phocein
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
MOB4
SynonymsGene synonyms aliases
2C4D, CGI-95, MOB1, MOB3, MOBKL3, PHOCN, PREI3
ChromosomeChromosome number
2
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2q33.1
SummarySummary of gene provided in NCBI Entrez Gene.
This gene was identified based on its similarity with the mouse counterpart. Studies of the mouse counterpart suggest that the expression of this gene may be regulated during oocyte maturation and preimplantation following zygotic gene activation. Alterna
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT023746 hsa-miR-1-3p Proteomics;Microarray 18668037
MIRT027305 hsa-miR-101-3p Sequencing 20371350
MIRT031318 hsa-miR-18a-5p Sequencing 20371350
MIRT677739 hsa-miR-3155a HITS-CLIP 23824327
MIRT677738 hsa-miR-3155b HITS-CLIP 23824327
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 18782753, 19156129, 24255178, 24366813, 26496610
GO:0005737 Component Cytoplasm ISS
GO:0005794 Component Golgi apparatus IDA 11251078
GO:0032580 Component Golgi cisterna membrane IEA
GO:0046872 Function Metal ion binding IEA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q9Y3A3
Protein name MOB-like protein phocein (2C4D) (Class II mMOB1) (Mob1 homolog 3) (Mob3) (Mps one binder kinase activator-like 3) (Preimplantation protein 3)
Protein function Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytos
PDB 5YF4 , 7K36
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03637 Mob1_phocein
44 209
Mob1/phocein family
Family
Sequence
Sequence length 225
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Schizophrenia Schizophrenia rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 28540026
Unknown
Disease name Disease term dbSNP ID References
Development disorder Child Development Disorders, Pervasive 28540026

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