MTCH2 (mitochondrial carrier 2)

Gene

• Entrez ID: 23788
• Gene name: Mitochondrial carrier 2
• Gene symbol: MTCH2
• Synonyms: HSPC032, MIMP, SLC25A50
• Chromosome: 11
• Chromosome location: 11p11.2
• Summary: This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT029895	hsa-miR-26b-5p	Microarray	19088304
MIRT051550	hsa-let-7e-5p	CLASH	23622248
MIRT047945	hsa-miR-30c-5p	CLASH	23622248
MIRT042361	hsa-miR-484	CLASH	23622248
MIRT038156	hsa-miR-423-5p	CLASH	23622248
MIRT437877	hsa-miR-135b-5p	Luciferase reporter assay, Western blot	23623609
MIRT1162384	hsa-miR-106a	CLIP-seq
MIRT1162385	hsa-miR-106b	CLIP-seq
MIRT1162386	hsa-miR-1224-5p	CLIP-seq
MIRT1162387	hsa-miR-1256	CLIP-seq
MIRT1162388	hsa-miR-1304	CLIP-seq
MIRT1162389	hsa-miR-150	CLIP-seq
MIRT1162390	hsa-miR-17	CLIP-seq
MIRT1162391	hsa-miR-203	CLIP-seq
MIRT1162392	hsa-miR-20a	CLIP-seq
MIRT1162393	hsa-miR-20b	CLIP-seq
MIRT1162394	hsa-miR-24	CLIP-seq
MIRT1162395	hsa-miR-2467-5p	CLIP-seq
MIRT1162396	hsa-miR-2682	CLIP-seq
MIRT1162397	hsa-miR-3121-5p	CLIP-seq
MIRT1162398	hsa-miR-3148	CLIP-seq
MIRT1162399	hsa-miR-3185	CLIP-seq
MIRT1162400	hsa-miR-3192	CLIP-seq
MIRT1162401	hsa-miR-3199	CLIP-seq
MIRT1162402	hsa-miR-339-5p	CLIP-seq
MIRT1162403	hsa-miR-3613-3p	CLIP-seq
MIRT1162404	hsa-miR-3915	CLIP-seq
MIRT1162405	hsa-miR-3928	CLIP-seq
MIRT1162406	hsa-miR-3940-5p	CLIP-seq
MIRT1162407	hsa-miR-3974	CLIP-seq
MIRT1162408	hsa-miR-4257	CLIP-seq
MIRT1162409	hsa-miR-4314	CLIP-seq
MIRT1162410	hsa-miR-449c	CLIP-seq
MIRT1162411	hsa-miR-4507	CLIP-seq
MIRT1162412	hsa-miR-4528	CLIP-seq
MIRT1162413	hsa-miR-4642	CLIP-seq
MIRT1162414	hsa-miR-4646-5p	CLIP-seq
MIRT1162415	hsa-miR-4653-3p	CLIP-seq
MIRT1162416	hsa-miR-4689	CLIP-seq
MIRT1162417	hsa-miR-4712-3p	CLIP-seq
MIRT1162418	hsa-miR-4713-5p	CLIP-seq
MIRT1162419	hsa-miR-4768-5p	CLIP-seq
MIRT1162420	hsa-miR-4778-5p	CLIP-seq
MIRT1162421	hsa-miR-4802-3p	CLIP-seq
MIRT1162422	hsa-miR-499a-5p	CLIP-seq
MIRT1162423	hsa-miR-519d	CLIP-seq
MIRT1162424	hsa-miR-520d-5p	CLIP-seq
MIRT1162425	hsa-miR-524-5p	CLIP-seq
MIRT1162426	hsa-miR-532-3p	CLIP-seq
MIRT1162427	hsa-miR-543	CLIP-seq
MIRT1162428	hsa-miR-545	CLIP-seq
MIRT1162429	hsa-miR-548a-3p	CLIP-seq
MIRT1162430	hsa-miR-548ae	CLIP-seq
MIRT1162431	hsa-miR-548aj	CLIP-seq
MIRT1162432	hsa-miR-548am	CLIP-seq
MIRT1162433	hsa-miR-548e	CLIP-seq
MIRT1162434	hsa-miR-548f	CLIP-seq
MIRT1162435	hsa-miR-548m	CLIP-seq
MIRT1162436	hsa-miR-548t	CLIP-seq
MIRT1162437	hsa-miR-548x	CLIP-seq
MIRT1162438	hsa-miR-624	CLIP-seq
MIRT1162439	hsa-miR-93	CLIP-seq
MIRT1162440	hsa-miR-940	CLIP-seq
MIRT2046572	hsa-miR-1208	CLIP-seq
MIRT1162394	hsa-miR-24	CLIP-seq
MIRT1162395	hsa-miR-2467-5p	CLIP-seq
MIRT2046573	hsa-miR-3140-5p	CLIP-seq
MIRT1162400	hsa-miR-3192	CLIP-seq
MIRT1162401	hsa-miR-3199	CLIP-seq
MIRT1162402	hsa-miR-339-5p	CLIP-seq
MIRT2046574	hsa-miR-3622a-3p	CLIP-seq
MIRT2046575	hsa-miR-3622b-3p	CLIP-seq
MIRT1162408	hsa-miR-4257	CLIP-seq
MIRT1162409	hsa-miR-4314	CLIP-seq
MIRT1162414	hsa-miR-4646-5p	CLIP-seq
MIRT1162424	hsa-miR-520d-5p	CLIP-seq
MIRT1162425	hsa-miR-524-5p	CLIP-seq
MIRT2046576	hsa-miR-579	CLIP-seq
MIRT2046577	hsa-miR-606	CLIP-seq
MIRT2046578	hsa-miR-668	CLIP-seq
MIRT1162384	hsa-miR-106a	CLIP-seq
MIRT1162385	hsa-miR-106b	CLIP-seq
MIRT2046572	hsa-miR-1208	CLIP-seq
MIRT1162386	hsa-miR-1224-5p	CLIP-seq
MIRT2275684	hsa-miR-1271	CLIP-seq
MIRT1162388	hsa-miR-1304	CLIP-seq
MIRT1162389	hsa-miR-150	CLIP-seq
MIRT1162390	hsa-miR-17	CLIP-seq
MIRT2275685	hsa-miR-182	CLIP-seq
MIRT2275686	hsa-miR-186	CLIP-seq
MIRT1162392	hsa-miR-20a	CLIP-seq
MIRT1162393	hsa-miR-20b	CLIP-seq
MIRT2275687	hsa-miR-302a	CLIP-seq
MIRT2275688	hsa-miR-302b	CLIP-seq
MIRT2275689	hsa-miR-302c	CLIP-seq
MIRT2275690	hsa-miR-302d	CLIP-seq
MIRT2275691	hsa-miR-302e	CLIP-seq
MIRT1162397	hsa-miR-3121-5p	CLIP-seq
MIRT2275692	hsa-miR-3133	CLIP-seq
MIRT1162398	hsa-miR-3148	CLIP-seq
MIRT2275693	hsa-miR-3154	CLIP-seq
MIRT2275694	hsa-miR-3174	CLIP-seq
MIRT2275695	hsa-miR-3179	CLIP-seq
MIRT1162400	hsa-miR-3192	CLIP-seq
MIRT1162401	hsa-miR-3199	CLIP-seq
MIRT2275696	hsa-miR-372	CLIP-seq
MIRT2275697	hsa-miR-373	CLIP-seq
MIRT1162404	hsa-miR-3915	CLIP-seq
MIRT1162405	hsa-miR-3928	CLIP-seq
MIRT2275698	hsa-miR-410	CLIP-seq
MIRT2275699	hsa-miR-4268	CLIP-seq
MIRT1162409	hsa-miR-4314	CLIP-seq
MIRT2275700	hsa-miR-4424	CLIP-seq
MIRT2275701	hsa-miR-4503	CLIP-seq
MIRT2275702	hsa-miR-4511	CLIP-seq
MIRT1162414	hsa-miR-4646-5p	CLIP-seq
MIRT1162416	hsa-miR-4689	CLIP-seq
MIRT1162417	hsa-miR-4712-3p	CLIP-seq
MIRT1162418	hsa-miR-4713-5p	CLIP-seq
MIRT1162419	hsa-miR-4768-5p	CLIP-seq
MIRT1162420	hsa-miR-4778-5p	CLIP-seq
MIRT2275703	hsa-miR-519a	CLIP-seq
MIRT2275704	hsa-miR-519b-3p	CLIP-seq
MIRT2275705	hsa-miR-519c-3p	CLIP-seq
MIRT1162423	hsa-miR-519d	CLIP-seq
MIRT2275706	hsa-miR-520a-3p	CLIP-seq
MIRT2275707	hsa-miR-520b	CLIP-seq
MIRT2275708	hsa-miR-520c-3p	CLIP-seq
MIRT2275709	hsa-miR-520d-3p	CLIP-seq
MIRT2275710	hsa-miR-520e	CLIP-seq
MIRT2275711	hsa-miR-520f	CLIP-seq
MIRT1162426	hsa-miR-532-3p	CLIP-seq
MIRT1162427	hsa-miR-543	CLIP-seq
MIRT1162436	hsa-miR-548t	CLIP-seq
MIRT2275712	hsa-miR-550b	CLIP-seq
MIRT2275713	hsa-miR-556-5p	CLIP-seq
MIRT2046576	hsa-miR-579	CLIP-seq
MIRT2046578	hsa-miR-668	CLIP-seq
MIRT2275714	hsa-miR-760	CLIP-seq
MIRT2275715	hsa-miR-890	CLIP-seq
MIRT1162439	hsa-miR-93	CLIP-seq
MIRT2275716	hsa-miR-96	CLIP-seq
MIRT2574612	hsa-miR-1182	CLIP-seq
MIRT2574613	hsa-miR-1245	CLIP-seq
MIRT2574614	hsa-miR-1915	CLIP-seq
MIRT2574615	hsa-miR-2053	CLIP-seq
MIRT1162394	hsa-miR-24	CLIP-seq
MIRT1162395	hsa-miR-2467-5p	CLIP-seq
MIRT2574616	hsa-miR-2909	CLIP-seq
MIRT2574617	hsa-miR-3120-5p	CLIP-seq
MIRT2574618	hsa-miR-3150a-5p	CLIP-seq
MIRT2574619	hsa-miR-3150b-5p	CLIP-seq
MIRT1162402	hsa-miR-339-5p	CLIP-seq
MIRT2574620	hsa-miR-3545-3p	CLIP-seq
MIRT2574621	hsa-miR-3591-5p	CLIP-seq
MIRT2574622	hsa-miR-3606	CLIP-seq
MIRT2574623	hsa-miR-361-5p	CLIP-seq
MIRT2574624	hsa-miR-3616-5p	CLIP-seq
MIRT2574625	hsa-miR-3617	CLIP-seq
MIRT2574626	hsa-miR-3647-5p	CLIP-seq
MIRT2574627	hsa-miR-3673	CLIP-seq
MIRT2574628	hsa-miR-377	CLIP-seq
MIRT2574629	hsa-miR-3908	CLIP-seq
MIRT2574630	hsa-miR-3913-3p	CLIP-seq
MIRT2574631	hsa-miR-3942-5p	CLIP-seq
MIRT1162408	hsa-miR-4257	CLIP-seq
MIRT2275699	hsa-miR-4268	CLIP-seq
MIRT2574632	hsa-miR-432	CLIP-seq
MIRT2275701	hsa-miR-4503	CLIP-seq
MIRT2574633	hsa-miR-450b-5p	CLIP-seq
MIRT2574634	hsa-miR-4635	CLIP-seq
MIRT2574635	hsa-miR-4703-5p	CLIP-seq
MIRT1162417	hsa-miR-4712-3p	CLIP-seq
MIRT2574636	hsa-miR-4725-5p	CLIP-seq
MIRT2574637	hsa-miR-4728-5p	CLIP-seq
MIRT2574638	hsa-miR-4760-3p	CLIP-seq
MIRT2574639	hsa-miR-4766-3p	CLIP-seq
MIRT2574640	hsa-miR-4775	CLIP-seq
MIRT1162422	hsa-miR-499a-5p	CLIP-seq
MIRT2574641	hsa-miR-504	CLIP-seq
MIRT2574642	hsa-miR-516a-3p	CLIP-seq
MIRT1162424	hsa-miR-520d-5p	CLIP-seq
MIRT1162425	hsa-miR-524-5p	CLIP-seq
MIRT2574643	hsa-miR-526b	CLIP-seq
MIRT2574644	hsa-miR-548a-5p	CLIP-seq
MIRT2574645	hsa-miR-548ab	CLIP-seq
MIRT2574646	hsa-miR-548ak	CLIP-seq
MIRT2574647	hsa-miR-548b-5p	CLIP-seq
MIRT2574648	hsa-miR-548c-5p	CLIP-seq
MIRT2574649	hsa-miR-548d-5p	CLIP-seq
MIRT2574650	hsa-miR-548h	CLIP-seq
MIRT2574651	hsa-miR-548i	CLIP-seq
MIRT2574652	hsa-miR-548j	CLIP-seq
MIRT2574653	hsa-miR-548n	CLIP-seq
MIRT2574654	hsa-miR-548w	CLIP-seq
MIRT2574655	hsa-miR-548y	CLIP-seq
MIRT2574656	hsa-miR-556-3p	CLIP-seq
MIRT2275713	hsa-miR-556-5p	CLIP-seq
MIRT2574657	hsa-miR-559	CLIP-seq
MIRT2574658	hsa-miR-573	CLIP-seq
MIRT2574659	hsa-miR-578	CLIP-seq
MIRT2574660	hsa-miR-641	CLIP-seq
MIRT2574661	hsa-miR-656	CLIP-seq
MIRT2574662	hsa-miR-921	CLIP-seq
MIRT2574663	hsa-miR-944	CLIP-seq
MIRT2574612	hsa-miR-1182	CLIP-seq
MIRT2574613	hsa-miR-1245	CLIP-seq
MIRT2275686	hsa-miR-186	CLIP-seq
MIRT2574614	hsa-miR-1915	CLIP-seq
MIRT2574615	hsa-miR-2053	CLIP-seq
MIRT1162394	hsa-miR-24	CLIP-seq
MIRT1162395	hsa-miR-2467-5p	CLIP-seq
MIRT2574616	hsa-miR-2909	CLIP-seq
MIRT2574617	hsa-miR-3120-5p	CLIP-seq
MIRT2275692	hsa-miR-3133	CLIP-seq
MIRT2574618	hsa-miR-3150a-5p	CLIP-seq
MIRT2574619	hsa-miR-3150b-5p	CLIP-seq
MIRT2275693	hsa-miR-3154	CLIP-seq
MIRT2275695	hsa-miR-3179	CLIP-seq
MIRT1162402	hsa-miR-339-5p	CLIP-seq
MIRT2574620	hsa-miR-3545-3p	CLIP-seq
MIRT2574621	hsa-miR-3591-5p	CLIP-seq
MIRT2574622	hsa-miR-3606	CLIP-seq
MIRT2574624	hsa-miR-3616-5p	CLIP-seq
MIRT2574625	hsa-miR-3617	CLIP-seq
MIRT2574626	hsa-miR-3647-5p	CLIP-seq
MIRT2574627	hsa-miR-3673	CLIP-seq
MIRT2574628	hsa-miR-377	CLIP-seq
MIRT2574629	hsa-miR-3908	CLIP-seq
MIRT2574630	hsa-miR-3913-3p	CLIP-seq
MIRT2574631	hsa-miR-3942-5p	CLIP-seq
MIRT1162408	hsa-miR-4257	CLIP-seq
MIRT2275699	hsa-miR-4268	CLIP-seq
MIRT2574632	hsa-miR-432	CLIP-seq
MIRT2685452	hsa-miR-4470	CLIP-seq
MIRT2685453	hsa-miR-4494	CLIP-seq
MIRT2685454	hsa-miR-4499	CLIP-seq
MIRT2275701	hsa-miR-4503	CLIP-seq
MIRT2574633	hsa-miR-450b-5p	CLIP-seq
MIRT2574634	hsa-miR-4635	CLIP-seq
MIRT2574635	hsa-miR-4703-5p	CLIP-seq
MIRT1162417	hsa-miR-4712-3p	CLIP-seq
MIRT2574636	hsa-miR-4725-5p	CLIP-seq
MIRT2574637	hsa-miR-4728-5p	CLIP-seq
MIRT2574638	hsa-miR-4760-3p	CLIP-seq
MIRT2574639	hsa-miR-4766-3p	CLIP-seq
MIRT2574640	hsa-miR-4775	CLIP-seq
MIRT1162422	hsa-miR-499a-5p	CLIP-seq
MIRT2574641	hsa-miR-504	CLIP-seq
MIRT2574642	hsa-miR-516a-3p	CLIP-seq
MIRT1162424	hsa-miR-520d-5p	CLIP-seq
MIRT1162425	hsa-miR-524-5p	CLIP-seq
MIRT2574643	hsa-miR-526b	CLIP-seq
MIRT2574644	hsa-miR-548a-5p	CLIP-seq
MIRT2574645	hsa-miR-548ab	CLIP-seq
MIRT2574646	hsa-miR-548ak	CLIP-seq
MIRT2574647	hsa-miR-548b-5p	CLIP-seq
MIRT2574648	hsa-miR-548c-5p	CLIP-seq
MIRT2574649	hsa-miR-548d-5p	CLIP-seq
MIRT2574650	hsa-miR-548h	CLIP-seq
MIRT2574651	hsa-miR-548i	CLIP-seq
MIRT2574652	hsa-miR-548j	CLIP-seq
MIRT2574653	hsa-miR-548n	CLIP-seq
MIRT2574654	hsa-miR-548w	CLIP-seq
MIRT2574655	hsa-miR-548y	CLIP-seq
MIRT2574656	hsa-miR-556-3p	CLIP-seq
MIRT2275713	hsa-miR-556-5p	CLIP-seq
MIRT2574657	hsa-miR-559	CLIP-seq
MIRT2574658	hsa-miR-573	CLIP-seq
MIRT2574659	hsa-miR-578	CLIP-seq
MIRT2574660	hsa-miR-641	CLIP-seq
MIRT2275714	hsa-miR-760	CLIP-seq
MIRT2275715	hsa-miR-890	CLIP-seq
MIRT2574662	hsa-miR-921	CLIP-seq
MIRT2574663	hsa-miR-944	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	HDA	21630459
GO:0005739	Component	Mitochondrion	IBA	21873635
GO:0005743	Component	Mitochondrial inner membrane	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IBA	21873635
GO:0016021	Component	Integral component of membrane	IEA
GO:0043065	Process	Positive regulation of apoptotic process	IBA	21873635
GO:0070585	Process	Protein localization to mitochondrion	IMP	23744079

Other IDs

• MIM: 613221
• HGNC: 17587
• e!Ensembl: ENSG00000109919

Protein

• UniProt ID: Q9Y6C9
• Protein name: Mitochondrial carrier homolog 2 (Met-induced mitochondrial protein)
• Protein function: Protein insertase that mediates insertion of transmembrane proteins into the mitochondrial outer membrane (PubMed:36264797). Catalyzes insertion of proteins with alpha-helical transmembrane regions, such as signal-anchored, tail-anchored and mul
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00153	Mito_carr	118 → 205	Mitochondrial carrier protein	Family

• Sequence:

  MADAASQVLLGSGLTILSQPLMYVKVLIQVGYEPLPPTIGRNIFGRQVCQLPGLFSYAQH
  IASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKEVSSSFDHV
  IKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFA
  GLVPRLLGDILSLWLCNSLAYLVNTYALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLV
  SNLMAVNNCGLAGGCPPYSPIYTSWIDCWCMLQKEGNMSRGNSLFFRKVPFGKTYCCDLK
  MLI

• Sequence length: 303

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Obesity	Obesity	rs34911341, rs74315349, rs1474810899, rs2282440, rs2491132, rs121918111, rs796065034, rs753856820, rs796065035, rs121918112, rs104894023, rs137852821, rs1580764441, rs137852822, rs137852823, rs137852824, rs13447324, rs121913562, rs121913564, rs74315393, rs121913556, rs2989924, rs193922650, rs193922685, rs193922687, rs751160202, rs1421085, rs747681609, rs1553400259, rs13447339, rs370479598, rs1554394014, rs1553174844, rs756232889, rs369841551, rs1557670950, rs1571321748, rs148538980, rs1572820988, rs1591461970, rs1419374563, rs745921568, rs144159890, rs1570714352, rs779783209, rs1573250294, rs1573254045, rs1580744791, rs1580746829, rs6548238, rs7138803, rs7754840	19079261

Unknown
Disease name	Disease term	dbSNP ID	References
Anxiety disorder	Anxiety		29942085