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BCL2L13 (BCL2 like 13)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
23786
Gene nameGene Name - the full gene name approved by the HGNC.
BCL2 like 13
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
BCL2L13
SynonymsGene synonyms aliases
BCL-RAMBO, Bcl2-L-13, MIL1
ChromosomeChromosome number
22
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
22q11.21
SummarySummary of gene provided in NCBI Entrez Gene.
This gene encodes a mitochondrially-localized protein with conserved B-cell lymphoma 2 homology motifs. Overexpression of the encoded protein results in apoptosis. Alternatively spliced transcript variants have been observed for this gene. [provided by Re
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT024899 hsa-miR-215-5p Microarray 19074876
MIRT025555 hsa-miR-34a-5p Sequencing 20371350
MIRT025589 hsa-miR-10a-5p Sequencing 20371350
MIRT026746 hsa-miR-192-5p Microarray 19074876
MIRT046068 hsa-miR-125b-5p CLASH 23622248
Transcription factors
Transcription factor Regulation Reference
ZIC1 Activation 20713527
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 16189514, 17360363, 25416956, 25910212, 26871637, 32296183, 32814053
GO:0005634 Component Nucleus IEA
GO:0005739 Component Mitochondrion IBA 21873635
GO:0005739 Component Mitochondrion IDA
GO:0005739 Component Mitochondrion NAS 11262395
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q9BXK5
Protein name Bcl-2-like protein 13 (Bcl2-L-13) (Bcl-rambo) (Protein Mil1)
Protein function May promote the activation of caspase-3 and apoptosis.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00452 Bcl-2
104 200
Apoptosis regulator proteins, Bcl-2 family
Family
Sequence
MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVK
TEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLH
KALQMLLSQPVTYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQ
FGVTYLEDYSAEYIIQQGGW
GTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPES
PTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSEN
NSSNSDIVHVEKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREP
DTEVITVEKSSPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREES
LVEELSPASEKKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVAL
ALRKK
Sequence length 485
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
KEGG
 
  Mitophagy - animal
Legionellosis
 
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Asthma Childhood asthma rs324981, rs121912630, rs150116809, rs4950928, rs708494, rs1581842283 29551627

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