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APOL2 (apolipoprotein L2)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
23780
Gene nameGene Name - the full gene name approved by the HGNC.
Apolipoprotein L2
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
APOL2
SynonymsGene synonyms aliases
APOL-II, APOL3
ChromosomeChromosome number
22
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
22q12.3
SummarySummary of gene provided in NCBI Entrez Gene.
This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles. Two transcript variants encoding the same protein have been
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT017248 hsa-miR-335-5p Microarray 18185580
MIRT024143 hsa-miR-221-3p Sequencing 20371350
MIRT025355 hsa-miR-34a-5p Proteomics 21566225
MIRT671855 hsa-miR-4755-3p HITS-CLIP 23824327
MIRT671854 hsa-miR-4284 HITS-CLIP 23824327
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005102 Function Signaling receptor binding NAS 11374903
GO:0005515 Function Protein binding IPI 32296183
GO:0005576 Component Extracellular region IEA
GO:0005789 Component Endoplasmic reticulum membrane NAS 11374903
GO:0006629 Process Lipid metabolic process NAS 11374903, 11944986
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q9BQE5
Protein name Apolipoprotein L2 (Apolipoprotein L-II) (ApoL-II)
Protein function May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles.
PDB 7LF8
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05461 ApoL
19 331
Apolipoprotein L
Family
Sequence
Sequence length 337
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Schizophrenia Schizophrenia rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313
Unknown
Disease name Disease term dbSNP ID References
Delusions Delusions
Hallucinations Hallucinations

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