CADM1 (cell adhesion molecule 1)

Gene

• Entrez ID: 23705
• Gene name: Cell adhesion molecule 1
• Gene symbol: CADM1
• Synonyms: BL2, IGSF4, IGSF4A, NECL2, Necl-2, RA175, ST17, SYNCAM, TSLC1, sTSLC-1, sgIGSF, synCAM1
• Chromosome: 11
• Chromosome location: 11q23.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT003888	hsa-miR-15a-5p	Reporter assay, qRT-PCR	18362358
MIRT004382	hsa-miR-16-5p	Reporter assay, qRT-PCR	18362358
MIRT004167	hsa-miR-192-5p	Microarray	16822819
MIRT029576	hsa-miR-26b-5p	Microarray	19088304
MIRT042379	hsa-miR-484	CLASH	23622248
MIRT036901	hsa-miR-877-3p	CLASH	23622248
MIRT054846	hsa-miR-182-5p	Luciferase reporter assay, qRT-PCR, Western blot	24445397
MIRT438847	hsa-miR-486-5p	qRT-PCR	23294929
MIRT438815	hsa-miR-214-3p	Luciferase reporter assay	23301758
MIRT438847	hsa-miR-486-5p	qRT-PCR	23294929
MIRT438815	hsa-miR-214-3p	Luciferase reporter assay	23301758
MIRT708158	hsa-miR-7161-3p	HITS-CLIP	21572407
MIRT708157	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT708156	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT708155	hsa-miR-6083	HITS-CLIP	21572407
MIRT708154	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT574844	hsa-miR-101-3p	PAR-CLIP	20371350
MIRT438847	hsa-miR-486-5p	PAR-CLIP	20371350
MIRT574848	hsa-miR-10a-5p	PAR-CLIP	20371350
MIRT574847	hsa-miR-10b-5p	PAR-CLIP	20371350
MIRT574846	hsa-miR-652-5p	PAR-CLIP	20371350
MIRT574845	hsa-miR-6732-3p	PAR-CLIP	20371350
MIRT574844	hsa-miR-101-3p	PAR-CLIP	20371350
MIRT574843	hsa-miR-144-3p	PAR-CLIP	20371350
MIRT574842	hsa-miR-7852-3p	PAR-CLIP	20371350
MIRT574841	hsa-miR-140-3p	PAR-CLIP	20371350
MIRT574840	hsa-miR-4703-3p	PAR-CLIP	20371350
MIRT058253	hsa-let-7a-2-3p	PAR-CLIP	20371350
MIRT058254	hsa-let-7g-3p	PAR-CLIP	20371350
MIRT574839	hsa-miR-3692-3p	PAR-CLIP	20371350
MIRT538752	hsa-miR-548an	PAR-CLIP	22012620
MIRT538751	hsa-miR-6768-3p	PAR-CLIP	22012620
MIRT538750	hsa-miR-4484	PAR-CLIP	22012620
MIRT538749	hsa-miR-4475	PAR-CLIP	22012620
MIRT538748	hsa-miR-6512-5p	PAR-CLIP	22012620
MIRT538747	hsa-miR-4327	PAR-CLIP	22012620
MIRT538746	hsa-miR-6892-5p	PAR-CLIP	22012620
MIRT538745	hsa-miR-1273e	PAR-CLIP	22012620
MIRT538744	hsa-miR-6885-3p	PAR-CLIP	22012620
MIRT494397	hsa-miR-4428	PAR-CLIP	23592263
MIRT494396	hsa-miR-361-3p	PAR-CLIP	23592263
MIRT494395	hsa-miR-6770-5p	PAR-CLIP	23592263
MIRT494394	hsa-miR-4479	PAR-CLIP	23592263
MIRT494393	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT494392	hsa-miR-4306	PAR-CLIP	23592263
MIRT494391	hsa-miR-4644	PAR-CLIP	23592263
MIRT732065	hsa-miR-126-3p	Luciferase reporter assay, qRT-PCR, Western blot	26464628
MIRT732065	hsa-miR-126-3p	Luciferase reporter assay, qRT-PCR, Western blot	26464628
MIRT736208	hsa-miR-25-3p	Microarray	31919459
MIRT737429	hsa-miR-424-5p	Western blotting, Microarray	31819525
MIRT708158	hsa-miR-7161-3p	HITS-CLIP	21572407
MIRT708157	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT708156	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT708155	hsa-miR-6083	HITS-CLIP	21572407
MIRT708154	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT574844	hsa-miR-101-3p	PAR-CLIP	20371350
MIRT438847	hsa-miR-486-5p	PAR-CLIP	20371350
MIRT574848	hsa-miR-10a-5p	PAR-CLIP	20371350
MIRT574847	hsa-miR-10b-5p	PAR-CLIP	20371350
MIRT574846	hsa-miR-652-5p	PAR-CLIP	20371350
MIRT574845	hsa-miR-6732-3p	PAR-CLIP	20371350
MIRT574844	hsa-miR-101-3p	PAR-CLIP	20371350
MIRT574843	hsa-miR-144-3p	PAR-CLIP	20371350
MIRT574842	hsa-miR-7852-3p	PAR-CLIP	20371350
MIRT574841	hsa-miR-140-3p	PAR-CLIP	20371350
MIRT574840	hsa-miR-4703-3p	PAR-CLIP	20371350
MIRT058253	hsa-let-7a-2-3p	PAR-CLIP	20371350
MIRT058254	hsa-let-7g-3p	PAR-CLIP	20371350
MIRT574839	hsa-miR-3692-3p	PAR-CLIP	20371350
MIRT538752	hsa-miR-548an	PAR-CLIP	22012620
MIRT538751	hsa-miR-6768-3p	PAR-CLIP	22012620
MIRT538750	hsa-miR-4484	PAR-CLIP	22012620
MIRT538749	hsa-miR-4475	PAR-CLIP	22012620
MIRT538748	hsa-miR-6512-5p	PAR-CLIP	22012620
MIRT538747	hsa-miR-4327	PAR-CLIP	22012620
MIRT538746	hsa-miR-6892-5p	PAR-CLIP	22012620
MIRT538745	hsa-miR-1273e	PAR-CLIP	22012620
MIRT538744	hsa-miR-6885-3p	PAR-CLIP	22012620
MIRT494397	hsa-miR-4428	PAR-CLIP	23592263
MIRT494396	hsa-miR-361-3p	PAR-CLIP	23592263
MIRT494395	hsa-miR-6770-5p	PAR-CLIP	23592263
MIRT494394	hsa-miR-4479	PAR-CLIP	23592263
MIRT494393	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT494392	hsa-miR-4306	PAR-CLIP	23592263
MIRT494391	hsa-miR-4644	PAR-CLIP	23592263
MIRT858452	hsa-miR-101	CLIP-seq
MIRT858453	hsa-miR-124	CLIP-seq
MIRT858454	hsa-miR-1279	CLIP-seq
MIRT858455	hsa-miR-144	CLIP-seq
MIRT858456	hsa-miR-15a	CLIP-seq
MIRT858457	hsa-miR-15b	CLIP-seq
MIRT858458	hsa-miR-16	CLIP-seq
MIRT858459	hsa-miR-193a-3p	CLIP-seq
MIRT858460	hsa-miR-193b	CLIP-seq
MIRT858461	hsa-miR-194	CLIP-seq
MIRT858462	hsa-miR-195	CLIP-seq
MIRT858463	hsa-miR-1972	CLIP-seq
MIRT858464	hsa-miR-2052	CLIP-seq
MIRT858465	hsa-miR-2054	CLIP-seq
MIRT858466	hsa-miR-23a	CLIP-seq
MIRT858467	hsa-miR-23b	CLIP-seq
MIRT858468	hsa-miR-23c	CLIP-seq
MIRT858469	hsa-miR-25	CLIP-seq
MIRT858470	hsa-miR-3065-5p	CLIP-seq
MIRT858471	hsa-miR-3143	CLIP-seq
MIRT858472	hsa-miR-3176	CLIP-seq
MIRT858473	hsa-miR-32	CLIP-seq
MIRT858474	hsa-miR-3607-3p	CLIP-seq
MIRT858475	hsa-miR-3613-3p	CLIP-seq
MIRT858476	hsa-miR-363	CLIP-seq
MIRT858477	hsa-miR-367	CLIP-seq
MIRT858478	hsa-miR-3686	CLIP-seq
MIRT858479	hsa-miR-375	CLIP-seq
MIRT858480	hsa-miR-3922-3p	CLIP-seq
MIRT858481	hsa-miR-424	CLIP-seq
MIRT858482	hsa-miR-4289	CLIP-seq
MIRT858483	hsa-miR-4329	CLIP-seq
MIRT858484	hsa-miR-4668-5p	CLIP-seq
MIRT858485	hsa-miR-4716-3p	CLIP-seq
MIRT858486	hsa-miR-4716-5p	CLIP-seq
MIRT858487	hsa-miR-4717-5p	CLIP-seq
MIRT858488	hsa-miR-4762-5p	CLIP-seq
MIRT858489	hsa-miR-494	CLIP-seq
MIRT858490	hsa-miR-495	CLIP-seq
MIRT858491	hsa-miR-497	CLIP-seq
MIRT858492	hsa-miR-505	CLIP-seq
MIRT858493	hsa-miR-506	CLIP-seq
MIRT858494	hsa-miR-543	CLIP-seq
MIRT858495	hsa-miR-545	CLIP-seq
MIRT858496	hsa-miR-548ac	CLIP-seq
MIRT858497	hsa-miR-548ae	CLIP-seq
MIRT858498	hsa-miR-548aj	CLIP-seq
MIRT858499	hsa-miR-548am	CLIP-seq
MIRT858500	hsa-miR-548d-3p	CLIP-seq
MIRT858501	hsa-miR-548x	CLIP-seq
MIRT858502	hsa-miR-548z	CLIP-seq
MIRT858503	hsa-miR-577	CLIP-seq
MIRT858504	hsa-miR-600	CLIP-seq
MIRT858505	hsa-miR-625	CLIP-seq
MIRT858506	hsa-miR-92a	CLIP-seq
MIRT858507	hsa-miR-92b	CLIP-seq
MIRT858452	hsa-miR-101	CLIP-seq
MIRT858463	hsa-miR-1972	CLIP-seq
MIRT858508	hsa-miR-214	CLIP-seq
MIRT858509	hsa-miR-219-1-3p	CLIP-seq
MIRT858510	hsa-miR-3117-5p	CLIP-seq
MIRT858511	hsa-miR-3129-3p	CLIP-seq
MIRT858512	hsa-miR-3148	CLIP-seq
MIRT858513	hsa-miR-3619-5p	CLIP-seq
MIRT858514	hsa-miR-3667-3p	CLIP-seq
MIRT858515	hsa-miR-3679-3p	CLIP-seq
MIRT858516	hsa-miR-4297	CLIP-seq
MIRT858517	hsa-miR-4446-5p	CLIP-seq
MIRT858518	hsa-miR-4690-5p	CLIP-seq
MIRT858519	hsa-miR-4698	CLIP-seq
MIRT858487	hsa-miR-4717-5p	CLIP-seq
MIRT858520	hsa-miR-4742-5p	CLIP-seq
MIRT858521	hsa-miR-514	CLIP-seq
MIRT858522	hsa-miR-514b-3p	CLIP-seq
MIRT858523	hsa-miR-761	CLIP-seq
MIRT858452	hsa-miR-101	CLIP-seq
MIRT1954945	hsa-miR-10a	CLIP-seq
MIRT1954946	hsa-miR-10b	CLIP-seq
MIRT1954947	hsa-miR-1228	CLIP-seq
MIRT1954948	hsa-miR-1252	CLIP-seq
MIRT858455	hsa-miR-144	CLIP-seq
MIRT858461	hsa-miR-194	CLIP-seq
MIRT1954949	hsa-miR-205	CLIP-seq
MIRT1954950	hsa-miR-2116	CLIP-seq
MIRT1954951	hsa-miR-329	CLIP-seq
MIRT1954952	hsa-miR-3614-5p	CLIP-seq
MIRT1954953	hsa-miR-362-3p	CLIP-seq
MIRT1954954	hsa-miR-3678-3p	CLIP-seq
MIRT1954955	hsa-miR-3692	CLIP-seq
MIRT858488	hsa-miR-4762-5p	CLIP-seq
MIRT1954956	hsa-miR-561	CLIP-seq
MIRT1954957	hsa-miR-759	CLIP-seq
MIRT2192532	hsa-miR-1271	CLIP-seq
MIRT2192533	hsa-miR-139-3p	CLIP-seq
MIRT2192534	hsa-miR-182	CLIP-seq
MIRT1954955	hsa-miR-3692	CLIP-seq
MIRT2192535	hsa-miR-412	CLIP-seq
MIRT2192536	hsa-miR-4324	CLIP-seq
MIRT858483	hsa-miR-4329	CLIP-seq
MIRT2192537	hsa-miR-4420	CLIP-seq
MIRT2192538	hsa-miR-4476	CLIP-seq
MIRT2192539	hsa-miR-450b-5p	CLIP-seq
MIRT858488	hsa-miR-4762-5p	CLIP-seq
MIRT858492	hsa-miR-505	CLIP-seq
MIRT2192540	hsa-miR-570	CLIP-seq
MIRT2192541	hsa-miR-96	CLIP-seq
MIRT2495770	hsa-miR-1305	CLIP-seq
MIRT2495771	hsa-miR-1323	CLIP-seq
MIRT2495772	hsa-miR-3689a-3p	CLIP-seq
MIRT2495773	hsa-miR-3689c	CLIP-seq
MIRT2495774	hsa-miR-4426	CLIP-seq
MIRT2495775	hsa-miR-4647	CLIP-seq
MIRT2495776	hsa-miR-4662b	CLIP-seq
MIRT2495777	hsa-miR-4728-5p	CLIP-seq
MIRT2495778	hsa-miR-548o	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001819	Process	Positive regulation of cytokine production	IDA	15811952
GO:0001913	Process	T cell mediated cytotoxicity	IDA	15811952
GO:0005102	Function	Signaling receptor binding	IPI	15811952
GO:0005102	Function	Signaling receptor binding	ISS	12826663
GO:0005515	Function	Protein binding	IPI	12234973, 20479255, 23871486, 25416956
GO:0005886	Component	Plasma membrane	IDA	15811952
GO:0005886	Component	Plasma membrane	TAS
GO:0005911	Component	Cell-cell junction	ISS	12826663
GO:0006915	Process	Apoptotic process	IEA
GO:0007156	Process	Homophilic cell adhesion via plasma membrane adhesion molecules	ISS	12826663
GO:0007157	Process	Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	ISS	12826663
GO:0007275	Process	Multicellular organism development	IEA
GO:0007283	Process	Spermatogenesis	IEA
GO:0008037	Process	Cell recognition	IDA	15811952
GO:0008037	Process	Cell recognition	ISS	12826663
GO:0016021	Component	Integral component of membrane	IEA
GO:0016032	Process	Viral process	IEA
GO:0016323	Component	Basolateral plasma membrane	ISS	12826663
GO:0030154	Process	Cell differentiation	IEA
GO:0030165	Function	PDZ domain binding	ISS	12826663
GO:0034332	Process	Adherens junction organization	TAS
GO:0042271	Process	Susceptibility to natural killer cell mediated cytotoxicity	IBA	21873635
GO:0042271	Process	Susceptibility to natural killer cell mediated cytotoxicity	IDA	15811952
GO:0042271	Process	Susceptibility to natural killer cell mediated cytotoxicity	ISS	12826663
GO:0042803	Function	Protein homodimerization activity	ISS	12826663
GO:0045202	Component	Synapse	IEA
GO:0045954	Process	Positive regulation of natural killer cell mediated cytotoxicity	IDA	15811952
GO:0045954	Process	Positive regulation of natural killer cell mediated cytotoxicity	ISS	12826663
GO:0050798	Process	Activated T cell proliferation	IDA	15811952
GO:0051606	Process	Detection of stimulus	IDA	15811952
GO:0051606	Process	Detection of stimulus	ISS	12826663

Other IDs

• MIM: 605686
• HGNC: 5951
• e!Ensembl: ENSG00000182985

Protein

• UniProt ID: Q9BY67
• Protein name: Cell adhesion molecule 1 (Immunoglobulin superfamily member 4) (IgSF4) (Nectin-like protein 2) (NECL-2) (Spermatogenic immunoglobulin superfamily) (SgIgSF) (Synaptic cell adhesion molecule) (SynCAM) (Tumor suppressor in lung cancer 1) (TSLC-1)
• Protein function: Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner (PubMed:12050160, PubMed:22438059). Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca(2+)-independent manner (By similarity). Interaction with CRTAM
• PDB: 3BIN, 4H5S
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07686	V-set	49 → 142	Immunoglobulin V-set domain	Domain
  PF08205	C2-set_2	148 → 230	CD80-like C2-set immunoglobulin domain	Domain
  PF13927	Ig_3	242 → 317		Domain

• Sequence:

  MASVVLPSGSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVA
  TISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEG
  RYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF
  KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQ
  YKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFI
  NNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTIITD
  SRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAADA
  DTAIINAEGGQNNSEEKKEYFI

• Sequence length: 442

Pathways

KEGG:

Cell adhesion molecules

Reactome:

Adherens junctions interactions
Nectin/Necl trans heterodimerization

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Autism	Autistic Disorder	rs121964908, rs121912597, rs2710102, rs7794745, rs142990298, rs62643608, rs181327458, rs797046134, rs869312704, rs1555013332, rs876657679, rs1057518999, rs1057518658, rs771827120, rs1555187899, rs773080572, rs753871454, rs1684130791, rs1684180699, rs1553510219, rs1684182454, rs1559060428, rs1553510677, rs1576352885, rs1574152522, rs1574152672, rs1696658542, rs1751123722, rs1750373491, rs1751075634	18957284
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158, rs80357524, rs80357115, rs80357945, rs80357729, rs80357609, rs80357259, rs80357981, rs80358063, rs80357389, rs80356862, rs80359876, rs80357580, rs80358053, rs80358089, rs80187739, rs397507241, rs80358069, rs80357590, rs80357284, rs80357941, rs80359261, rs80359272, rs80359276, rs276174813, rs80358474, rs80359316, rs1555282969, rs80359388, rs80359499, rs80359505, rs80359520, rs80359526, rs80359533, rs56253082, rs80358824, rs80359554, rs80359636, rs80359651, rs80359659, rs80359011, rs80359012, rs80359013, rs80359718, rs397507410, rs81002812, rs80359730, rs80359152, rs80359159, rs397507419, rs28897759, rs80359211, rs80359775, rs397514577, rs397507584, rs80358435, rs80358456, rs80359340, rs80359343, rs80359365, rs80358579, rs397507670, rs80358593, rs80359406, rs80359444, rs80359454, rs276174853, rs276174854, rs80359483, rs80359537, rs80358815, rs80358843, rs80359558, rs80359560, rs80359594, rs80358893, rs28897743, rs397507900, rs397507906, rs397507918, rs80358971, rs80358981, rs397507941, rs80359030, rs80359035, rs41293511, rs397507396, rs81002806, rs80359112, rs397508006, rs81002893, rs45580035, rs80359760, rs397508051, rs80359772, rs4987049, rs80359777, rs80357770, rs397508867, rs62625303, rs397508874, rs80357506, rs80357287, rs273898674, rs80358042, rs80358083, rs80357058, rs41286296, rs80357960, rs80356945, rs80357223, rs386134270, rs80358116, rs80357856, rs80357424, rs397509050, rs80357485, rs80357966, rs397509067, rs80357310, rs80356866, rs80357260, rs80357437, rs80358023, rs80358086, rs80357133, rs80356993, rs80357997, rs80357239, rs80357227, rs397509243, rs80356969, rs80356959, rs63750617, rs63751319, rs587779315, rs200640585, rs398122546, rs80357543, rs398122687, rs80359328, rs398122779, rs398122783, rs62517194, rs80358029, rs515726060, rs180177103, rs180177111, rs180177133, rs587776527, rs180177135, rs180177136, rs515726117, rs587779813, rs587779909, rs587780024, rs587780100, rs28909982, rs121908698, rs180177100, rs587780210, rs587780240, rs587780639, rs587781269, rs587781353, rs587781471, rs587781658, rs587781697, rs587781730, rs587781894, rs587781948, rs587782005, rs587782011, rs200928781, rs587781558, rs370228071, rs587782245, rs587782401, rs180177110, rs587782504, rs72552322, rs587782531, rs587782620, rs587782680, rs587782774, rs587782818, rs730881411, rs730881389, rs564652222, rs397507768, rs587776419, rs730881868, rs730881940, rs56383036, rs758972589, rs201089102, rs730881348, rs786202608, rs786201886, rs786203318, rs786203775, rs786203714, rs786202033, rs750621215, rs786203884, rs786203650, rs772821016, rs863224521, rs864622223, rs864622655, rs375699023, rs876659572, rs768362387, rs876659535, rs876658957, rs483353072, rs876659435, rs267608041, rs876661113, rs730881369, rs878853535, rs772228129, rs878855122, rs760551339, rs80359596, rs397509222, rs886039630, rs886039683, rs886040828, rs587781799, rs886040374, rs886040649, rs397507967, rs878854957, rs886040043, rs1057517589, rs1060502769, rs866380588, rs863224765, rs1064793243, rs747563556, rs1555074976, rs1064795885, rs753961188, rs1064794708, rs869312772, rs1064793887, rs1131690820, rs1135401928, rs1135401868, rs1135401859, rs1553370324, rs397507630, rs1555283160, rs1555283251, rs1555283262, rs1555283361, rs1555286298, rs1555288462, rs886040950, rs1555289566, rs776323117, rs80357123, rs1555579627, rs1555580697, rs80358054, rs1555593302, rs1328985852, rs763470424, rs1555139694, rs878854697, rs1555461217, rs1555461765, rs774684620, rs766416564, rs1554558613, rs1305740166, rs1555461460, rs1555461407, rs1555461586, rs1555567202, rs1555607022, rs1555069815, rs1442299125, rs1474786480, rs1555084947, rs1555457867, rs141087784, rs1482641121, rs1564830522, rs1565469955, rs1565503137, rs864622613, rs755263466, rs757679199, rs1593903166, rs1597801649, rs1603293306, rs879253880, rs80358754, rs1597062038, rs45494092, rs1603275367, rs887358871, rs1597091518, rs1966967065, rs1064793049, rs2082872908, rs2085078278, rs2072475243	17260099
Breast carcinoma	Breast Carcinoma	rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451, rs397507859, rs80359709, rs80359742, rs80359205, rs80357627, rs80357004, rs80357571, rs80357767, rs80357653, rs80358086, rs80357608, rs28897696, rs41293465, rs146650273, rs63751017, rs63750617, rs63750726, rs63750199, rs63749848, rs398122618, rs398122653, rs397509211, rs80357791, rs121912666, rs587778541, rs121908698, rs536907995, rs587781302, rs140342925, rs587781506, rs587782652, rs587782849, rs587783057, rs10520699, rs11852999, rs139770721, rs374950566, rs786202800, rs863224451, rs377153250, rs747727055, rs876658804, rs780001540, rs760815829, rs878854926, rs775248597, rs886040658, rs886040192, rs786203523, rs886040319, rs397508006, rs587782011, rs1060502772, rs1555461727, rs1553333072, rs1114167702, rs1257401983, rs886040950, rs1060502759, rs774684620, rs142947311, rs1555580883, rs748513310, rs376170600, rs863224499, rs1593909229, rs748453607, rs1294578913, rs1574737047, rs1593909960, rs2081922847, rs2082559544, rs2053694038	17260099
Marfan syndrome	Mammary Carcinoma, Human	rs137854456, rs137854457, rs267606796, rs137854458, rs137854459, rs137854460, rs137854470, rs137854471, rs267606797, rs137854461, rs137854462, rs137854463, rs869025419, rs137854464, rs137854465, rs137854466, rs137854467, rs387906547, rs387906548, rs137854469, rs137854473, rs1131692050, rs112989722, rs137854474, rs137854476, rs140593, rs1555395819, rs137854478, rs137854479, rs137854480, rs137854481, rs137854482, rs137854483, rs137854484, rs137854485, rs112289537, rs193922181, rs193922182, rs193922185, rs140603, rs193922187, rs193922188, rs193921256, rs112660651, rs193922193, rs193922194, rs193922197, rs193922198, rs193922199, rs193922203, rs193922204, rs193922205, rs193922206, rs111401431, rs193922207, rs113871094, rs111671429, rs193922216, rs193922219, rs193922220, rs193922223, rs193922224, rs193922225, rs193922226, rs193922227, rs193922228, rs193922230, rs193922235, rs147195031, rs193922236, rs193922239, rs193922240, rs193922241, rs193922246, rs397514558, rs398122934, rs397515753, rs397515754, rs397515755, rs397515756, rs397515757, rs113812345, rs397515758, rs397515759, rs397515762, rs25403, rs397515765, rs397515766, rs397515767, rs397515768, rs397515769, rs397515770, rs397515771, rs25404, rs397515773, rs397515774, rs397515775, rs397515776, rs397515778, rs397515779, rs397515781, rs112202622, rs397515782, rs397515784, rs397515785, rs397515786, rs397515788, rs397515789, rs397515790, rs397515791, rs397515792, rs397515793, rs397515794, rs397515797, rs397515798, rs397515799, rs397515801, rs397515802, rs397515803, rs397515804, rs397515805, rs397515808, rs397515810, rs397515811, rs397515812, rs111231312, rs267606798, rs397515814, rs113905529, rs397515816, rs397515817, rs397515818, rs397515819, rs397515820, rs363853, rs113249837, rs397515821, rs111929350, rs397515823, rs397515824, rs113086760, rs397515825, rs397515826, rs397515827, rs363807, rs397515828, rs397515829, rs397515830, rs397515831, rs397515833, rs111687884, rs113080385, rs397515834, rs397515836, rs113001196, rs397515840, rs397515845, rs397515846, rs397515847, rs397515848, rs397515851, rs397515852, rs397515853, rs397515854, rs111856492, rs397515859, rs397515861, rs397515863, rs397515864, rs397515865, rs397515866, rs397515867, rs137854855, rs199474693, rs587782944, rs587782947, rs587782948, rs672601352, rs876658120, rs727504651, rs727503054, rs727504315, rs727504411, rs727503057, rs727504454, rs200309328, rs363811, rs727504410, rs363821, rs727504347, rs727505006, rs727505110, rs730880356, rs727505269, rs727503058, rs727504421, rs730880107, rs730880104, rs730880103, rs730880102, rs730880101, rs730880106, rs730880100, rs730880105, rs730880099, rs112645512, rs730880108, rs730880098, rs730880097, rs794728321, rs794728283, rs794728280, rs794728336, rs794728272, rs794728160, rs794728271, rs794728270, rs794728319, rs794728262, rs794728251, rs76702162, rs794728335, rs794728334, rs794728246, rs763091520, rs794728333, rs794728237, rs761857514, rs794728234, rs140630, rs794728231, rs794728228, rs794728225, rs794728308, rs794728216, rs794728221, rs763449629, rs201058219, rs794728210, rs794728208, rs794728206, rs794728199, rs794728195, rs794728194, rs794728193, rs794728190, rs1555399381, rs794728176, rs1555399968, rs113422242, rs794728326, rs794728166, rs794728325, rs794728165, rs794728162, rs794728213, rs869025417, rs112642323, rs869025416, rs869025415, rs869025424, rs869025423, rs869025414, rs869025422, rs869025413, rs869025412, rs869025411, rs869025418, rs869025426, rs869025406, rs869025421, rs869025425, rs869025404, rs869025420, rs869025403, rs398122833, rs876657645, rs878853686, rs878853676, rs886038919, rs886038795, rs187553035, rs886038869, rs886038949, rs886038967, rs886038976, rs886038848, rs886038940, rs886038877, rs886039038, rs886038817, rs886038963, rs886039036, rs886038797, rs886039550, rs886041482, rs1057517855, rs1057518912, rs1057518973, rs1057519502, rs1057521100, rs1057521102, rs1057518881, rs1057520617, rs1057521101, rs1555394445, rs369058466, rs1060501069, rs1060501031, rs778966916, rs1060501043, rs1555397663, rs1060501017, rs1060501094, rs1060501065, rs1555393848, rs1555394151, rs1060501051, rs1060501013, rs1060501054, rs1060501048, rs1060501089, rs1060501039, rs1555398160, rs1060501022, rs1060501024, rs1060501086, rs1060501058, rs1060501036, rs1060501100, rs1060501042, rs1060501059, rs1555397743, rs1060501021, rs1060501027, rs1060501096, rs1060501038, rs1060501050, rs1064794130, rs112118237, rs1064793980, rs1064793118, rs1064793636, rs1064794282, rs1064793559, rs1085307921, rs1085308004, rs1085307468, rs112907302, rs1131691479, rs1131691373, rs1131691467, rs1131691938, rs1131691311, rs1131691806, rs1131691317, rs1555393827, rs363804, rs1555397738, rs1555399144, rs1555400274, rs1555394195, rs1555398836, rs113543334, rs1555399825, rs1555394626, rs1555395256, rs1555395257, rs1555396427, rs1555397548, rs1555398173, rs1555404803, rs1232880706, rs1555393825, rs1555394567, rs1555396998, rs1555394928, rs1555397203, rs112375043, rs1555397720, rs140599, rs1555399150, rs1555400373, rs1555405041, rs1555395229, rs1555397671, rs775417975, rs1555398774, rs1555399368, rs1555394904, rs1555395987, rs1555397424, rs1555398377, rs1555398835, rs1555401011, rs1555405043, rs1555394580, rs1555397404, rs1555398511, rs1555395826, rs1555399372, rs1555399821, rs1555399836, rs1555400063, rs363810, rs1555397655, rs1555395756, rs1555395742, rs1555393844, rs112550005, rs1555395002, rs1555395658, rs765387131, rs1555396429, rs1555396835, rs1555397014, rs1555397016, rs778710767, rs1555397557, rs1555397704, rs140648, rs1555398406, rs1555398681, rs1555399257, rs1555399361, rs1555399764, rs1555405056, rs1555393510, rs1555395980, rs1555396789, rs1555399094, rs1555399378, rs1555399816, rs1555395645, rs371097218, rs1555398278, rs1555394238, rs1555396418, rs1206813753, rs1555399271, rs1555405044, rs113544411, rs1555395663, rs1555397216, rs1555398989, rs1555399149, rs1555401670, rs1555395001, rs1445085747, rs1555393538, rs1555393565, rs1404133653, rs1555394450, rs1555394581, rs1555394633, rs1555394900, rs1555395189, rs1555395261, rs1052480459, rs1555395480, rs1555395670, rs363806, rs1555395820, rs1555396419, rs1555396765, rs1296209846, rs794728233, rs1555396853, rs1555396863, rs1555397197, rs1555397204, rs1555397212, rs1555397713, rs1555397736, rs1555398139, rs1555398144, rs1555398409, rs1555398510, rs1555398520, rs1555398524, rs1555398667, rs1555399089, rs1555399482, rs1555399763, rs1555401002, rs794728323, rs1555393508, rs1555393514, rs1555393525, rs1555393532, rs1555393653, rs1555393657, rs1555393824, rs1555393831, rs112196241, rs1555393847, rs1555393862, rs1555393863, rs1555393866, rs113935744, rs1555393882, rs1555393886, rs1555393889, rs1555394138, rs1555394144, rs1555394146, rs1555394148, rs1555394149, rs1555394152, rs1555394153, rs1555394189, rs1555394197, rs1555394206, rs1555394212, rs1555394218, rs1555394220, rs1555394235, rs1555394245, rs1555394246, rs1057520728, rs1555394390, rs1555394391, rs537570299, rs1555394397, rs1555394398, rs1555394399, rs1555394402, rs1555394407, rs1555394412, rs1555394435, rs1555394436, rs1555394441, rs1555394556, rs1555394557, rs1555394559, rs1555394561, rs1555394570, rs397515844, rs1555394571, rs1555394574, rs1555394579, rs1555394582, rs534811966, rs111588631, rs1555394628, rs1555394629, rs1555394630, rs1555394631, rs1555394641, rs1555394644, rs1555394647, rs1555394756, rs886051245, rs1555394775, rs1555394776, rs1555394777, rs1555394779, rs1555394780, rs1555394783, rs1555394901, rs1555394906, rs1555394925, rs794728253, rs886039158, rs1555395013, rs1555395187, rs1555395188, rs1555395203, rs1555395205, rs363815, rs1246984265, rs794728245, rs1555395263, rs1555395267, rs1555395456, rs1555395475, rs1555395482, rs1555395638, rs1555395641, rs1555395648, rs1555395653, rs1555395659, rs111239111, rs1555395745, rs1555395747, rs1555395753, rs1555395757, rs1555395766, rs1555395767, rs1555395843, rs1555395846, rs1555395849, rs1555395978, rs1555395981, rs1555395984, rs1555395989, rs1555395990, rs1260109901, rs1555396186, rs1555396188, rs1555396198, rs1555396199, rs1555396201, rs1555396202, rs1555396205, rs1555396213, rs1555396424, rs1555396426, rs1555396428, rs1555396435, rs1555396630, rs1555396635, rs1555396636, rs1555396639, rs1555396757, rs1555396769, rs1555396838, rs1555396844, rs140627, rs1555396858, rs1555396990, rs1555396991, rs1555396993, rs769588424, rs1555397022, rs1555397024, rs1555397160, rs1555397174, rs1555397176, rs1555397193, rs1555397209, rs1555397210, rs1555397214, rs1060501076, rs113082854, rs113693945, rs111978932, rs1555397403, rs1555397419, rs1555397420, rs1555397421, rs1555397536, rs1555397537, rs1555397540, rs1555397542, rs1555397543, rs1555397545, rs1555397546, rs1555397670, rs1555397692, rs1555397718, rs1555397723, rs1555397744, rs113393517, rs1555398148, rs1555398152, rs1555398174, rs1555398176, rs1555398179, rs1555398282, rs1555398287, rs1555398380, rs1555398394, rs1555398397, rs1555398401, rs1555398404, rs1555398407, rs1555398413, rs1555398501, rs1555398508, rs1555398512, rs1555398513, rs1555398515, rs1555398521, rs794728205, rs1555398527, rs1555398551, rs1060501075, rs1555398566, rs1555398572, rs1555398580, rs1555398582, rs140597, rs1555398622, rs1555398624, rs1555398625, rs112547596, rs1555398627, rs1555398633, rs1555398637, rs1555398642, rs778867355, rs1555398648, rs1555398659, rs1293095681, rs1060501040, rs987202268, rs1555398672, rs1555398673, rs1555398677, rs1555398793, rs1555398803, rs1555398811, rs1555398826, rs1555398833, rs1555398974, rs1555398981, rs778900586, rs1555398988, rs1555398994, rs1555398995, rs1555398996, rs1555399093, rs869025405, rs1555399101, rs1555399146, rs1555399160, rs1555399162, rs1555399164, rs1555399165, rs1555399193, rs1555399195, rs1555399202, rs1555399204, rs1555399206, rs201778577, rs1555399210, rs1555399214, rs1555399270, rs1555399273, rs1555399281, rs1555399371, rs1555399385, rs1555399477, rs1555399484, rs1555399761, rs1555399775, rs1555399802, rs1555399804, rs1555399837, rs1555399840, rs1555399940, rs1555399944, rs1555399949, rs1555399953, rs1555399954, rs1555399955, rs1555399959, rs1555399962, rs1555399963, rs1060501041, rs1555399974, rs1555399976, rs1555399977, rs1555400049, rs794728172, rs1555400062, rs1555400064, rs1555400066, rs1555400267, rs1555400268, rs1555400278, rs794728168, rs1555400279, rs1156747241, rs1555400288, rs1555400371, rs1555400372, rs1555400379, rs1555400385, rs587782943, rs1555400387, rs1555400406, rs1439533354, rs746201757, rs1555400595, rs1555400603, rs1555400604, rs1555400606, rs1555400609, rs752010116, rs1555400612, rs1555400616, rs1555401004, rs1555401005, rs146348130, rs1555401667, rs1555401671, rs1555401676, rs1555401679, rs1555401687, rs1555401689, rs1555401695, rs1555401697, rs1555401701, rs1555404799, rs1555404800, rs200295020, rs1555404810, rs1555404820, rs1555405031, rs1555405039, rs1555405045, rs1555405530, rs794728292, rs1555405533, rs1555405536, rs1555405537, rs111764111, rs1555405658, rs1555405664, rs774371494, rs1555405673, rs1555407399, rs1555407414, rs1555407423, rs1555407429, rs886041536, rs1555404806, rs1566911709, rs1566913974, rs1566894226, rs1566895223, rs1566897376, rs1566902526, rs1566915277, rs1566897374, rs1566897420, rs1566891655, rs1346043320, rs1566922396, rs1566891706, rs1566894783, rs1566913670, rs1555394196, rs1566891454, rs1566891406, rs1566891404, rs1566895262, rs1566891645, rs1566895225, rs1566896114, rs1566898399, rs1566904011, rs1566906537, rs1566908956, rs1566909766, rs1566919599, rs1566937712, rs1566915335, rs1566891675, rs1566904526, rs1566906506, rs1566900540, rs1566894230, rs1555395206, rs1566891797, rs1597512576, rs1597523873, rs1597581001, rs1597516325, rs1057524757, rs1597506641, rs1597520781, rs1597593695, rs1597529829, rs1597520625, rs1597579923, rs1597531796, rs1008275504, rs1597567249, rs1597569265, rs1597652471, rs1597516347, rs1597577114, rs1597633163, rs1597519658, rs1597593852, rs1597516501, rs1566913982, rs1555393859, rs1597513708, rs368978109, rs1480832655, rs1597520683, rs1597522390, rs1597522553, rs1597529748, rs1597533707, rs1597537815, rs1597545309, rs1597545836, rs1597563234, rs1597563280, rs1597564359, rs772108557, rs1597568968, rs1597574236, rs1597574308, rs1597577975, rs193922179, rs1597581005, rs1597593736, rs1597623670, rs1597625734, rs1597631662, rs113604459, rs1597633183, rs1597633219, rs1597518951, rs1555394781, rs1597525871, rs1597526073, rs1597569159, rs1597569536, rs1597563934, rs1597545199, rs1364210063, rs1597552583, rs1597520619, rs1597540854, rs1597591602, rs1597569551, rs1597548716, rs1597553721, rs112728248, rs1597537858, rs1597517935, rs1597540907, rs1597552388, rs1597591643, rs1597529841, rs1597506547, rs1597509836, rs1597529686, rs1566897404, rs1597533713, rs1597543486, rs1597545257, rs1597545345, rs1597548672, rs1597562812, rs1597563287, rs1597571391, rs1555400052, rs1597583989, rs363852, rs1597547226, rs363808, rs974604498, rs2043595650, rs2043526284, rs2042997306, rs1555397195, rs886039054, rs1555397213, rs2042873946	17260099

Unknown
Disease name	Disease term	dbSNP ID	References
Anorexia	Anorexia Nervosa		31308545
Mammary neoplasms	Mammary Neoplasms, Human, Mammary Neoplasms		17260099
Melancholia	Melancholia		22113448
Mental depression	Endogenous depression, Depressive disorder, Unipolar Depression, Depressive Syndrome, Depression, Neurotic	rs587778876, rs587778877	22113448