Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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23683 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Protein kinase D3 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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PRKD3 |
SynonymsGene synonyms aliases
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EPK2, PKC-NU, PKD3, PRKCN, nPKC-NU |
ChromosomeChromosome number
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2 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2p22.2 |
SummarySummary of gene provided in NCBI Entrez Gene.
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This gene belongs to the multigene protein kinase D family of serine/threonine kinases, which bind diacylglycerol and phorbol esters. Members of this family are characterized by an N-terminal regulatory domain comprised of a tandem repeat of cysteine-rich |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
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UniProt ID |
O94806 |
Protein name |
Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu) |
Protein function |
Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress (By similarity). |
PDB |
2D9Z
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Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00130 |
C1_1 |
155 → 206 |
Phorbol esters/diacylglycerol binding domain (C1 domain) |
Domain |
PF00130 |
C1_1 |
272 → 324 |
Phorbol esters/diacylglycerol binding domain (C1 domain) |
Domain |
PF00169 |
PH |
417 → 532 |
PH domain |
Domain |
PF00069 |
Pkinase |
577 → 832 |
Protein kinase domain |
Domain |
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Sequence |
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Sequence length |
890 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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