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SSBP2 (single stranded DNA binding protein 2)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
23635
Gene nameGene Name - the full gene name approved by the HGNC.
Single stranded DNA binding protein 2
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
SSBP2
SynonymsGene synonyms aliases
HSPC116, SOSS-B2
ChromosomeChromosome number
5
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
5q14.1
SummarySummary of gene provided in NCBI Entrez Gene.
This gene encodes a subunit of a protein complex that interacts with single-stranded DNA and is involved in the DNA damage response and maintenance of genome stability. The encoded protein may also play a role in telomere repair. A variant of this gene ma
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT679312 hsa-miR-8062 HITS-CLIP 23824327
MIRT679311 hsa-miR-6513-3p HITS-CLIP 23824327
MIRT679310 hsa-miR-4258 HITS-CLIP 23824327
MIRT679309 hsa-miR-7108-3p HITS-CLIP 23824327
MIRT679308 hsa-miR-4485-5p HITS-CLIP 23824327
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003697 Function Single-stranded DNA binding NAS 12079286
GO:0005634 Component Nucleus IBA 21873635
GO:0005737 Component Cytoplasm IDA
GO:0006355 Process Regulation of transcription, DNA-templated NAS 12079286
GO:0045944 Process Positive regulation of transcription by RNA polymerase II IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID P81877
Protein name Single-stranded DNA-binding protein 2 (Sequence-specific single-stranded-DNA-binding protein 2)
PDB 6IWV , 6TYD , 8HIB
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04503 SSDP
83 125
Family
PF04503 SSDP
124 338
Family
Sequence
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGF
LHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNIPPGDGMPVGPVPP
GFF
QPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTP
PRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNY
VGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPGSDGPMGGLGGM
ESHHMNGSLGSGDMDSISKNSPNNMSLSNQPGTPRDDG
EMGGNFLNPFQSESYSPSMTMS
V
Sequence length 361
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Glioblastoma Glioblastoma, Glioblastoma Multiforme rs121913500, rs886042842, rs1555138291, rs1558518449, rs1567176006, rs1558650888 22472174
Prostate cancer Malignant neoplasm of prostate rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 18559593
Unknown
Disease name Disease term dbSNP ID References
Bipolar disorder Bipolar Disorder, Depression, Bipolar 31043756
Manic disorder Manic, Manic Disorder 31043756
Prostatic neoplasms Prostatic Neoplasms 18559593

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