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NUDCD3 (NudC domain containing 3)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
23386
Gene nameGene Name - the full gene name approved by the HGNC.
NudC domain containing 3
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
NUDCD3
SynonymsGene synonyms aliases
NudCL
ChromosomeChromosome number
7
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
7p13
SummarySummary of gene provided in NCBI Entrez Gene.
The product of this gene functions to maintain the stability of dynein intermediate chain. Depletion of this gene product results in aggregation and degradation of dynein intermediate chain, mislocalization of the dynein complex from kinetochores, spindle
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT025842 hsa-miR-7-5p Microarray 19073608
MIRT049022 hsa-miR-92a-3p CLASH 23622248
MIRT045654 hsa-miR-149-5p CLASH 23622248
MIRT042837 hsa-miR-324-3p CLASH 23622248
MIRT610881 hsa-miR-548ae-3p HITS-CLIP 23824327
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 16754861, 20562859, 25036637, 28514442
GO:0005737 Component Cytoplasm IBA 21873635
GO:0005868 Component Cytoplasmic dynein complex IDA 25205765
GO:0006457 Process Protein folding IBA 21873635
GO:0051082 Function Unfolded protein binding IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q8IVD9
Protein name NudC domain-containing protein 3
PDB 1WGV
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF14050 Nudc_N
8 67
N-terminal conserved domain of Nudc.
Family
PF04969 CS
188 267
CS domain
Domain
Sequence
METGAAELYDQALLGILQHVGNVQDFLRVLFGFLYRKTDFYRLLRHPSDRMGFPPGAAQA
LVLQVFK
TFDHMARQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDS
TTELDGHQEVEKVQPPGPVKEMAHGSQEAEAPGAVAGAAEVPREPPILPRIQEQFQKNPD
SYNGAVRENYTWSQDYTDLEVRVPVPKHVVKGKQVSVALSSSSIRVAMLEENGERVLMEG
KLTHKINTESSLWSLEPGKCVLVNLSK
VGEYWWNAILEGEEPIDIDKINKERSMATVDEE
EQAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDAEGSPFRGQRFDPAMFNISPGAVQ
F
Sequence length 361
Interactions View interactions
Associated diseases
Unknown
Disease name Disease term dbSNP ID References
Liver neoplasms Liver neoplasms 19233941
Liver cancer Malignant neoplasm of liver 19233941

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