TTC28 (tetratricopeptide repeat domain 28)
|
Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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23331 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Tetratricopeptide repeat domain 28 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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TTC28 |
SynonymsGene synonyms aliases
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TPRBK |
ChromosomeChromosome number
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22 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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22q12.1 |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
|
UniProt ID |
Q96AY4 |
Protein name |
Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) |
Protein function |
During mitosis, may be involved in the condensation of spindle midzone microtubules, leading to the formation of midbody. |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF13176 |
TPR_7 |
276 → 311 |
Tetratricopeptide repeat |
Repeat |
PF13424 |
TPR_12 |
311 → 386 |
|
Repeat |
PF13424 |
TPR_12 |
351 → 426 |
|
Repeat |
PF13424 |
TPR_12 |
472 → 546 |
|
Repeat |
PF13424 |
TPR_12 |
552 → 626 |
|
Repeat |
PF13424 |
TPR_12 |
636 → 706 |
|
Repeat |
PF13424 |
TPR_12 |
713 → 786 |
|
Repeat |
PF13424 |
TPR_12 |
832 → 909 |
|
Repeat |
PF13424 |
TPR_12 |
915 → 989 |
|
Repeat |
PF13424 |
TPR_12 |
995 → 1069 |
|
Repeat |
PF13424 |
TPR_12 |
1075 → 1149 |
|
Repeat |
PF12770 |
CHAT |
1390 → 1713 |
CHAT domain |
Domain |
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Sequence |
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Sequence length |
2481 |
Interactions |
View interactions |
Associated diseases
|
Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Breast carcinoma |
Breast Carcinoma |
rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451, rs397507859, rs80359709, rs80359742, rs80359205, rs80357627, rs80357004, rs80357571, rs80357767, rs80357653, rs80358086, rs80357608, rs28897696, rs41293465, rs146650273, rs63751017, rs63750617, rs63750726, rs63750199, rs63749848, rs398122618, rs398122653, rs397509211, rs80357791, rs121912666, rs587778541, rs121908698, rs536907995, rs587781302, rs140342925, rs587781506, rs587782652, rs587782849, rs587783057, rs10520699, rs11852999, rs139770721, rs374950566, rs786202800, rs863224451, rs377153250, rs747727055, rs876658804, rs780001540, rs760815829, rs878854926, rs775248597, rs886040658, rs886040192, rs786203523, rs886040319, rs397508006, rs587782011, rs1060502772, rs1555461727, rs1553333072, rs1114167702, rs1257401983, rs886040950, rs1060502759, rs774684620, rs142947311, rs1555580883, rs748513310, rs376170600, rs863224499, rs1593909229, rs748453607, rs1294578913, rs1574737047, rs1593909960, rs2081922847, rs2082559544, rs2053694038 |
29059683 |
Obesity |
Obesity |
rs34911341, rs74315349, rs1474810899, rs2282440, rs2491132, rs121918111, rs796065034, rs753856820, rs796065035, rs121918112, rs104894023, rs137852821, rs1580764441, rs137852822, rs137852823, rs137852824, rs13447324, rs121913562, rs121913564, rs74315393, rs121913556, rs2989924, rs193922650, rs193922685, rs193922687, rs751160202, rs1421085, rs747681609, rs1553400259, rs13447339, rs370479598, rs1554394014, rs1553174844, rs756232889, rs369841551, rs1557670950, rs1571321748, rs148538980, rs1572820988, rs1591461970, rs1419374563, rs745921568, rs144159890, rs1570714352, rs779783209, rs1573250294, rs1573254045, rs1580744791, rs1580746829, rs6548238, rs7138803, rs7754840 |
21552555 |
Prostate cancer |
Prostate carcinoma, Prostate cancer, familial |
rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 |
29892016, 29117387, 29892016 |
Prostate cancer, hereditary |
PROSTATE CANCER, HEREDITARY, 1 |
rs387906327, rs193929331, rs74315365, rs10993994, rs397516896, rs794729219, rs121913349, rs587782641, rs1114167673, rs1597371666, rs2073394466 |
29892016 |
|
Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Eczema |
Eczema |
|
30595370 |
Ovarian neoplasm |
ovarian neoplasm |
|
28346442 |
Ovarian serous adenocarcinoma |
Ovarian Serous Adenocarcinoma |
|
28346442 |
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