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SLC9A8 (solute carrier family 9 member A8)

Gene

23315

Solute carrier family 9 member A8

SLC9A8

NHE-8, NHE8

20q13.13

Sodium-hydrogen exchangers (NHEs), such as SLC9A8, are integral transmembrane proteins that exchange extracellular Na+ for intracellular H+. NHEs have multiple functions, including intracellular pH homeostasis, cell volume regulation, and electroneutral N

Show/Hide all(360)

miRTarBase ID	miRNA	Experiments	Reference
MIRT713755	hsa-miR-4293	HITS-CLIP	19536157
MIRT713754	hsa-miR-596	HITS-CLIP	19536157
MIRT713753	hsa-miR-1199-5p	HITS-CLIP	19536157
MIRT713752	hsa-miR-6751-3p	HITS-CLIP	19536157
MIRT713751	hsa-miR-4534	HITS-CLIP	19536157
MIRT713750	hsa-miR-8082	HITS-CLIP	19536157
MIRT713749	hsa-miR-3134	HITS-CLIP	19536157
MIRT441898	hsa-miR-6807-5p	HITS-CLIP	19536157
MIRT713755	hsa-miR-4293	HITS-CLIP	19536157
MIRT713754	hsa-miR-596	HITS-CLIP	19536157
MIRT713753	hsa-miR-1199-5p	HITS-CLIP	19536157
MIRT713752	hsa-miR-6751-3p	HITS-CLIP	19536157
MIRT713751	hsa-miR-4534	HITS-CLIP	19536157
MIRT713750	hsa-miR-8082	HITS-CLIP	19536157
MIRT713749	hsa-miR-3134	HITS-CLIP	19536157
MIRT441898	hsa-miR-6807-5p	HITS-CLIP	19536157
MIRT630590	hsa-miR-3662	HITS-CLIP	23824327
MIRT630589	hsa-miR-3065-3p	HITS-CLIP	23824327
MIRT630588	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT630587	hsa-miR-3607-3p	HITS-CLIP	23824327
MIRT630586	hsa-miR-1537-5p	HITS-CLIP	23824327
MIRT630585	hsa-miR-4718	HITS-CLIP	23824327
MIRT630584	hsa-miR-4999-5p	HITS-CLIP	23824327
MIRT441901	hsa-miR-6830-5p	PAR-CLIP	22291592
MIRT441900	hsa-miR-4480	PAR-CLIP	22291592
MIRT441899	hsa-miR-4792	PAR-CLIP	22291592
MIRT441898	hsa-miR-6807-5p	PAR-CLIP	22291592
MIRT441897	hsa-miR-192-3p	PAR-CLIP	22291592
MIRT441901	hsa-miR-6830-5p	PAR-CLIP	23708386
MIRT441900	hsa-miR-4480	PAR-CLIP	23708386
MIRT441899	hsa-miR-4792	PAR-CLIP	23708386
MIRT441898	hsa-miR-6807-5p	PAR-CLIP	23708386
MIRT441897	hsa-miR-192-3p	PAR-CLIP	23708386
MIRT441901	hsa-miR-6830-5p	PAR-CLIP	22100165
MIRT441900	hsa-miR-4480	PAR-CLIP	22100165
MIRT441899	hsa-miR-4792	PAR-CLIP	22100165
MIRT441898	hsa-miR-6807-5p	PAR-CLIP	22100165
MIRT441897	hsa-miR-192-3p	PAR-CLIP	22100165
MIRT713755	hsa-miR-4293	HITS-CLIP	19536157
MIRT713754	hsa-miR-596	HITS-CLIP	19536157
MIRT713753	hsa-miR-1199-5p	HITS-CLIP	19536157
MIRT713752	hsa-miR-6751-3p	HITS-CLIP	19536157
MIRT713751	hsa-miR-4534	HITS-CLIP	19536157
MIRT713750	hsa-miR-8082	HITS-CLIP	19536157
MIRT713749	hsa-miR-3134	HITS-CLIP	19536157
MIRT441898	hsa-miR-6807-5p	HITS-CLIP	19536157
MIRT713755	hsa-miR-4293	HITS-CLIP	19536157
MIRT713754	hsa-miR-596	HITS-CLIP	19536157
MIRT713753	hsa-miR-1199-5p	HITS-CLIP	19536157
MIRT713752	hsa-miR-6751-3p	HITS-CLIP	19536157
MIRT713751	hsa-miR-4534	HITS-CLIP	19536157
MIRT713750	hsa-miR-8082	HITS-CLIP	19536157
MIRT713749	hsa-miR-3134	HITS-CLIP	19536157
MIRT441898	hsa-miR-6807-5p	HITS-CLIP	19536157
MIRT630590	hsa-miR-3662	HITS-CLIP	23824327
MIRT630589	hsa-miR-3065-3p	HITS-CLIP	23824327
MIRT630588	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT630587	hsa-miR-3607-3p	HITS-CLIP	23824327
MIRT630586	hsa-miR-1537-5p	HITS-CLIP	23824327
MIRT630585	hsa-miR-4718	HITS-CLIP	23824327
MIRT630584	hsa-miR-4999-5p	HITS-CLIP	23824327
MIRT441901	hsa-miR-6830-5p	PAR-CLIP	22291592
MIRT441900	hsa-miR-4480	PAR-CLIP	22291592
MIRT441899	hsa-miR-4792	PAR-CLIP	22291592
MIRT441898	hsa-miR-6807-5p	PAR-CLIP	22291592
MIRT441897	hsa-miR-192-3p	PAR-CLIP	22291592
MIRT441901	hsa-miR-6830-5p	PAR-CLIP	23708386
MIRT441900	hsa-miR-4480	PAR-CLIP	23708386
MIRT441899	hsa-miR-4792	PAR-CLIP	23708386
MIRT441898	hsa-miR-6807-5p	PAR-CLIP	23708386
MIRT441897	hsa-miR-192-3p	PAR-CLIP	23708386
MIRT441901	hsa-miR-6830-5p	PAR-CLIP	22100165
MIRT441900	hsa-miR-4480	PAR-CLIP	22100165
MIRT441899	hsa-miR-4792	PAR-CLIP	22100165
MIRT441898	hsa-miR-6807-5p	PAR-CLIP	22100165
MIRT441897	hsa-miR-192-3p	PAR-CLIP	22100165
MIRT1369084	hsa-miR-1178	CLIP-seq
MIRT1369085	hsa-miR-1206	CLIP-seq
MIRT1369086	hsa-miR-1224-5p	CLIP-seq
MIRT1369087	hsa-miR-1226	CLIP-seq
MIRT1369088	hsa-miR-1266	CLIP-seq
MIRT1369089	hsa-miR-1270	CLIP-seq
MIRT1369090	hsa-miR-1273f	CLIP-seq
MIRT1369091	hsa-miR-1304	CLIP-seq
MIRT1369092	hsa-miR-1468	CLIP-seq
MIRT1369093	hsa-miR-151-3p	CLIP-seq
MIRT1369094	hsa-miR-15a	CLIP-seq
MIRT1369095	hsa-miR-15b	CLIP-seq
MIRT1369096	hsa-miR-16	CLIP-seq
MIRT1369097	hsa-miR-181a	CLIP-seq
MIRT1369098	hsa-miR-181b	CLIP-seq
MIRT1369099	hsa-miR-181c	CLIP-seq
MIRT1369100	hsa-miR-181d	CLIP-seq
MIRT1369101	hsa-miR-1825	CLIP-seq
MIRT1369102	hsa-miR-1911	CLIP-seq
MIRT1369103	hsa-miR-1912	CLIP-seq
MIRT1369104	hsa-miR-195	CLIP-seq
MIRT1369105	hsa-miR-199a-5p	CLIP-seq
MIRT1369106	hsa-miR-199b-5p	CLIP-seq
MIRT1369107	hsa-miR-218	CLIP-seq
MIRT1369108	hsa-miR-30a	CLIP-seq
MIRT1369109	hsa-miR-30b	CLIP-seq
MIRT1369110	hsa-miR-30c	CLIP-seq
MIRT1369111	hsa-miR-30d	CLIP-seq
MIRT1369112	hsa-miR-30e	CLIP-seq
MIRT1369113	hsa-miR-3120-3p	CLIP-seq
MIRT1369114	hsa-miR-3121-3p	CLIP-seq
MIRT1369115	hsa-miR-3126-5p	CLIP-seq
MIRT1369116	hsa-miR-3130-5p	CLIP-seq
MIRT1369117	hsa-miR-3150a-3p	CLIP-seq
MIRT1369118	hsa-miR-3154	CLIP-seq
MIRT1369119	hsa-miR-3175	CLIP-seq
MIRT1369120	hsa-miR-3190	CLIP-seq
MIRT1369121	hsa-miR-3529	CLIP-seq
MIRT1369122	hsa-miR-3611	CLIP-seq
MIRT1369123	hsa-miR-3649	CLIP-seq
MIRT1369124	hsa-miR-3652	CLIP-seq
MIRT1369125	hsa-miR-3664-3p	CLIP-seq
MIRT1369126	hsa-miR-379	CLIP-seq
MIRT1369127	hsa-miR-3915	CLIP-seq
MIRT1369128	hsa-miR-3919	CLIP-seq
MIRT1369129	hsa-miR-3921	CLIP-seq
MIRT1369130	hsa-miR-3927	CLIP-seq
MIRT1369131	hsa-miR-3974	CLIP-seq
MIRT1369132	hsa-miR-424	CLIP-seq
MIRT1369133	hsa-miR-4262	CLIP-seq
MIRT1369134	hsa-miR-4263	CLIP-seq
MIRT1369135	hsa-miR-4267	CLIP-seq
MIRT1369136	hsa-miR-4269	CLIP-seq
MIRT1369137	hsa-miR-4286	CLIP-seq
MIRT1369138	hsa-miR-4292	CLIP-seq
MIRT1369139	hsa-miR-4308	CLIP-seq
MIRT1369140	hsa-miR-4327	CLIP-seq
MIRT1369141	hsa-miR-4419a	CLIP-seq
MIRT1369142	hsa-miR-4430	CLIP-seq
MIRT1369143	hsa-miR-4436b-3p	CLIP-seq
MIRT1369144	hsa-miR-4446-3p	CLIP-seq
MIRT1369145	hsa-miR-4462	CLIP-seq
MIRT1369146	hsa-miR-4463	CLIP-seq
MIRT1369147	hsa-miR-4482	CLIP-seq
MIRT1369148	hsa-miR-4492	CLIP-seq
MIRT1369149	hsa-miR-4498	CLIP-seq
MIRT1369150	hsa-miR-4499	CLIP-seq
MIRT1369151	hsa-miR-4505	CLIP-seq
MIRT1369152	hsa-miR-4509	CLIP-seq
MIRT1369153	hsa-miR-4510	CLIP-seq
MIRT1369154	hsa-miR-4514	CLIP-seq
MIRT1369155	hsa-miR-4518	CLIP-seq
MIRT1369156	hsa-miR-451b	CLIP-seq
MIRT1369157	hsa-miR-4649-3p	CLIP-seq
MIRT1369158	hsa-miR-4651	CLIP-seq
MIRT1369159	hsa-miR-4653-5p	CLIP-seq
MIRT1369160	hsa-miR-4671-5p	CLIP-seq
MIRT1369161	hsa-miR-4676-5p	CLIP-seq
MIRT1369162	hsa-miR-4681	CLIP-seq
MIRT1369163	hsa-miR-4683	CLIP-seq
MIRT1369164	hsa-miR-4689	CLIP-seq
MIRT1369165	hsa-miR-4692	CLIP-seq
MIRT1369166	hsa-miR-4705	CLIP-seq
MIRT1369167	hsa-miR-4709-3p	CLIP-seq
MIRT1369168	hsa-miR-4717-5p	CLIP-seq
MIRT1369169	hsa-miR-4733-3p	CLIP-seq
MIRT1369170	hsa-miR-4742-5p	CLIP-seq
MIRT1369171	hsa-miR-4751	CLIP-seq
MIRT1369172	hsa-miR-4768-5p	CLIP-seq
MIRT1369173	hsa-miR-4786-3p	CLIP-seq
MIRT1369174	hsa-miR-4790-3p	CLIP-seq
MIRT1369175	hsa-miR-4799-5p	CLIP-seq
MIRT1369176	hsa-miR-483-3p	CLIP-seq
MIRT1369177	hsa-miR-485-3p	CLIP-seq
MIRT1369178	hsa-miR-491-5p	CLIP-seq
MIRT1369179	hsa-miR-497	CLIP-seq
MIRT1369180	hsa-miR-498	CLIP-seq
MIRT1369181	hsa-miR-513a-5p	CLIP-seq
MIRT1369182	hsa-miR-516b	CLIP-seq
MIRT1369183	hsa-miR-526b	CLIP-seq
MIRT1369184	hsa-miR-541	CLIP-seq
MIRT1369185	hsa-miR-543	CLIP-seq
MIRT1369186	hsa-miR-544b	CLIP-seq
MIRT1369187	hsa-miR-548m	CLIP-seq
MIRT1369188	hsa-miR-575	CLIP-seq
MIRT1369189	hsa-miR-576-3p	CLIP-seq
MIRT1369190	hsa-miR-576-5p	CLIP-seq
MIRT1369191	hsa-miR-586	CLIP-seq
MIRT1369192	hsa-miR-608	CLIP-seq
MIRT1369193	hsa-miR-620	CLIP-seq
MIRT1369194	hsa-miR-634	CLIP-seq
MIRT1369195	hsa-miR-636	CLIP-seq
MIRT1369196	hsa-miR-654-5p	CLIP-seq
MIRT1369197	hsa-miR-668	CLIP-seq
MIRT1369198	hsa-miR-7	CLIP-seq
MIRT1369199	hsa-miR-711	CLIP-seq
MIRT1369200	hsa-miR-762	CLIP-seq
MIRT1369201	hsa-miR-767-3p	CLIP-seq
MIRT1369202	hsa-miR-885-3p	CLIP-seq
MIRT1369203	hsa-miR-939	CLIP-seq
MIRT2109639	hsa-miR-1205	CLIP-seq
MIRT2109640	hsa-miR-1343	CLIP-seq
MIRT2109641	hsa-miR-149	CLIP-seq
MIRT1369094	hsa-miR-15a	CLIP-seq
MIRT1369095	hsa-miR-15b	CLIP-seq
MIRT1369096	hsa-miR-16	CLIP-seq
MIRT2109642	hsa-miR-1909	CLIP-seq
MIRT1369104	hsa-miR-195	CLIP-seq
MIRT2109643	hsa-miR-3150b-3p	CLIP-seq
MIRT2109644	hsa-miR-3166	CLIP-seq
MIRT2109645	hsa-miR-3176	CLIP-seq
MIRT2109646	hsa-miR-3922-3p	CLIP-seq
MIRT1369132	hsa-miR-424	CLIP-seq
MIRT2109647	hsa-miR-4265	CLIP-seq
MIRT2109648	hsa-miR-4296	CLIP-seq
MIRT2109649	hsa-miR-4322	CLIP-seq
MIRT2109650	hsa-miR-4417	CLIP-seq
MIRT2109651	hsa-miR-4418	CLIP-seq
MIRT2109652	hsa-miR-4468	CLIP-seq
MIRT2109653	hsa-miR-4519	CLIP-seq
MIRT1369164	hsa-miR-4689	CLIP-seq
MIRT2109654	hsa-miR-4757-5p	CLIP-seq
MIRT2109655	hsa-miR-4784	CLIP-seq
MIRT1369179	hsa-miR-497	CLIP-seq
MIRT2109656	hsa-miR-499a-5p	CLIP-seq
MIRT2109657	hsa-miR-509-3-5p	CLIP-seq
MIRT2109658	hsa-miR-509-5p	CLIP-seq
MIRT2109659	hsa-miR-658	CLIP-seq
MIRT2332841	hsa-miR-103a	CLIP-seq
MIRT2332842	hsa-miR-107	CLIP-seq
MIRT2332843	hsa-miR-1183	CLIP-seq
MIRT2332844	hsa-miR-1245b-3p	CLIP-seq
MIRT2332845	hsa-miR-125a-5p	CLIP-seq
MIRT2332846	hsa-miR-125b	CLIP-seq
MIRT1369088	hsa-miR-1266	CLIP-seq
MIRT1369090	hsa-miR-1273f	CLIP-seq
MIRT2332847	hsa-miR-128	CLIP-seq
MIRT2332848	hsa-miR-143	CLIP-seq
MIRT1369092	hsa-miR-1468	CLIP-seq
MIRT2332849	hsa-miR-1470	CLIP-seq
MIRT2109641	hsa-miR-149	CLIP-seq
MIRT2332850	hsa-miR-1587	CLIP-seq
MIRT2332851	hsa-miR-182	CLIP-seq
MIRT2332852	hsa-miR-183	CLIP-seq
MIRT2332853	hsa-miR-1908	CLIP-seq
MIRT2109642	hsa-miR-1909	CLIP-seq
MIRT2332854	hsa-miR-1976	CLIP-seq
MIRT2332855	hsa-miR-210	CLIP-seq
MIRT2332856	hsa-miR-23a	CLIP-seq
MIRT2332857	hsa-miR-23b	CLIP-seq
MIRT2332858	hsa-miR-23c	CLIP-seq
MIRT2332859	hsa-miR-27a	CLIP-seq
MIRT2332860	hsa-miR-27b	CLIP-seq
MIRT2332861	hsa-miR-3121-5p	CLIP-seq
MIRT1369115	hsa-miR-3126-5p	CLIP-seq
MIRT2332862	hsa-miR-3127-5p	CLIP-seq
MIRT2332863	hsa-miR-3133	CLIP-seq
MIRT2109643	hsa-miR-3150b-3p	CLIP-seq
MIRT1369118	hsa-miR-3154	CLIP-seq
MIRT2332864	hsa-miR-3184	CLIP-seq
MIRT2332865	hsa-miR-3189-5p	CLIP-seq
MIRT2332866	hsa-miR-342-5p	CLIP-seq
MIRT2332867	hsa-miR-345	CLIP-seq
MIRT2332868	hsa-miR-3620	CLIP-seq
MIRT2332869	hsa-miR-3650	CLIP-seq
MIRT1369124	hsa-miR-3652	CLIP-seq
MIRT2332870	hsa-miR-3657	CLIP-seq
MIRT2332871	hsa-miR-3677-5p	CLIP-seq
MIRT2332872	hsa-miR-3714	CLIP-seq
MIRT2332873	hsa-miR-3907	CLIP-seq
MIRT1369128	hsa-miR-3919	CLIP-seq
MIRT1369129	hsa-miR-3921	CLIP-seq
MIRT2332874	hsa-miR-3935	CLIP-seq
MIRT1369131	hsa-miR-3974	CLIP-seq
MIRT2332875	hsa-miR-423-5p	CLIP-seq
MIRT2332876	hsa-miR-4256	CLIP-seq
MIRT2109647	hsa-miR-4265	CLIP-seq
MIRT2332877	hsa-miR-4268	CLIP-seq
MIRT2332878	hsa-miR-4270	CLIP-seq
MIRT2332879	hsa-miR-4283	CLIP-seq
MIRT2109648	hsa-miR-4296	CLIP-seq
MIRT2332880	hsa-miR-4319	CLIP-seq
MIRT2109649	hsa-miR-4322	CLIP-seq
MIRT2109650	hsa-miR-4417	CLIP-seq
MIRT1369141	hsa-miR-4419a	CLIP-seq
MIRT1369142	hsa-miR-4430	CLIP-seq
MIRT1369143	hsa-miR-4436b-3p	CLIP-seq
MIRT2332881	hsa-miR-4441	CLIP-seq
MIRT1369144	hsa-miR-4446-3p	CLIP-seq
MIRT2332882	hsa-miR-4447	CLIP-seq
MIRT2332883	hsa-miR-4448	CLIP-seq
MIRT2332884	hsa-miR-4455	CLIP-seq
MIRT2332885	hsa-miR-4469	CLIP-seq
MIRT2332886	hsa-miR-4472	CLIP-seq
MIRT1369148	hsa-miR-4492	CLIP-seq
MIRT2332887	hsa-miR-4493	CLIP-seq
MIRT1369149	hsa-miR-4498	CLIP-seq
MIRT1369151	hsa-miR-4505	CLIP-seq
MIRT1369153	hsa-miR-4510	CLIP-seq
MIRT1369155	hsa-miR-4518	CLIP-seq
MIRT1369157	hsa-miR-4649-3p	CLIP-seq
MIRT1369158	hsa-miR-4651	CLIP-seq
MIRT1369159	hsa-miR-4653-5p	CLIP-seq
MIRT2332888	hsa-miR-4656	CLIP-seq
MIRT2332889	hsa-miR-4660	CLIP-seq
MIRT2332890	hsa-miR-4664-5p	CLIP-seq
MIRT2332891	hsa-miR-4667-3p	CLIP-seq
MIRT2332892	hsa-miR-4669	CLIP-seq
MIRT2332893	hsa-miR-4675	CLIP-seq
MIRT1369164	hsa-miR-4689	CLIP-seq
MIRT2332894	hsa-miR-4715-5p	CLIP-seq
MIRT2332895	hsa-miR-4719	CLIP-seq
MIRT2332896	hsa-miR-4731-5p	CLIP-seq
MIRT2332897	hsa-miR-4741	CLIP-seq
MIRT1369171	hsa-miR-4751	CLIP-seq
MIRT2109654	hsa-miR-4757-5p	CLIP-seq
MIRT1369172	hsa-miR-4768-5p	CLIP-seq
MIRT2332898	hsa-miR-4770	CLIP-seq
MIRT2109655	hsa-miR-4784	CLIP-seq
MIRT1369173	hsa-miR-4786-3p	CLIP-seq
MIRT1369176	hsa-miR-483-3p	CLIP-seq
MIRT2332899	hsa-miR-485-5p	CLIP-seq
MIRT2332900	hsa-miR-486-3p	CLIP-seq
MIRT1369181	hsa-miR-513a-5p	CLIP-seq
MIRT2332901	hsa-miR-548an	CLIP-seq
MIRT1369192	hsa-miR-608	CLIP-seq
MIRT2332902	hsa-miR-615-5p	CLIP-seq
MIRT2332903	hsa-miR-617	CLIP-seq
MIRT2332904	hsa-miR-645	CLIP-seq
MIRT2332905	hsa-miR-663	CLIP-seq
MIRT2332906	hsa-miR-665	CLIP-seq
MIRT1369197	hsa-miR-668	CLIP-seq
MIRT2332907	hsa-miR-760	CLIP-seq
MIRT1369200	hsa-miR-762	CLIP-seq
MIRT1369202	hsa-miR-885-3p	CLIP-seq
MIRT2332844	hsa-miR-1245b-3p	CLIP-seq
MIRT1369124	hsa-miR-3652	CLIP-seq
MIRT1369142	hsa-miR-4430	CLIP-seq
MIRT1369151	hsa-miR-4505	CLIP-seq
MIRT1369158	hsa-miR-4651	CLIP-seq
MIRT1369163	hsa-miR-4683	CLIP-seq
MIRT2394824	hsa-miR-4688	CLIP-seq
MIRT2394825	hsa-miR-4736	CLIP-seq
MIRT1369192	hsa-miR-608	CLIP-seq
MIRT2459940	hsa-miR-2467-5p	CLIP-seq
MIRT1369114	hsa-miR-3121-3p	CLIP-seq
MIRT2459941	hsa-miR-3188	CLIP-seq
MIRT2459942	hsa-miR-3975	CLIP-seq
MIRT1369134	hsa-miR-4263	CLIP-seq
MIRT1369157	hsa-miR-4649-3p	CLIP-seq
MIRT1369175	hsa-miR-4799-5p	CLIP-seq
MIRT2332899	hsa-miR-485-5p	CLIP-seq
MIRT1369186	hsa-miR-544b	CLIP-seq
MIRT1369190	hsa-miR-576-5p	CLIP-seq
MIRT2332907	hsa-miR-760	CLIP-seq
MIRT2627242	hsa-miR-1257	CLIP-seq
MIRT2627243	hsa-miR-3658	CLIP-seq
MIRT2627244	hsa-miR-4317	CLIP-seq
MIRT2627245	hsa-miR-4323	CLIP-seq
MIRT2627246	hsa-miR-4522	CLIP-seq
MIRT2627247	hsa-miR-4677-3p	CLIP-seq
MIRT2627248	hsa-miR-4679	CLIP-seq
MIRT2627249	hsa-miR-4690-3p	CLIP-seq
MIRT2627250	hsa-miR-4758-3p	CLIP-seq

Show/Hide all(12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	TAS
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005794	Component	Golgi apparatus	IBA	21873635
GO:0006811	Process	Ion transport	TAS
GO:0015385	Function	Sodium:proton antiporter activity	IBA	21873635
GO:0015386	Function	Potassium:proton antiporter activity	IBA	21873635
GO:0016021	Component	Integral component of membrane	IEA
GO:0035725	Process	Sodium ion transmembrane transport	IEA
GO:0051453	Process	Regulation of intracellular pH	IBA	21873635
GO:0071805	Process	Potassium ion transmembrane transport	IBA	21873635
GO:0098656	Process	Anion transmembrane transport	IEA
GO:1902600	Process	Proton transmembrane transport	IEA

MIM	HGNC	e!Ensembl
612730	20728	ENSG00000197818

Protein

UniProt ID

Q9Y2E8

Protein name

Sodium/hydrogen exchanger 8 (Na(+)/H(+) exchanger 8) (NHE-8) (Solute carrier family 9 member 8)

Protein function

Na(+)/H(+) antiporter. Mediates the electoneutral exchange of intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry (PubMed:15522866). Acts as an Na(+)/H(+) exchanger in the trans-Golgi. Contributes to the regulation of pH regulat

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00999	Na_H_Exchanger	62 → 473	Sodium/hydrogen exchanger family	Family

Sequence

MGEKMAEEERFPNTTHEGFNVTLHTTLVVTTKLVLPTPGKPILPVQTGEQAQQEEQSSGM
TIFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKIIEFKKLANWKEEEM
FRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFLGQAD
VISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFGESILNDAVSIVLTNTA
EGLTRKNMSDVSGWQTFLQALDYFLKMFFGSAALGTLTGLISALVLKHIDLRKTPSLEFG
MMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQILMQQTLRTVAFLCET
CVFAFLGLSIFSFPHKFEISFVIWCIVLVLFGRAVNIFPLSYLLNFFRDHKITPKMMFIM
WFSGLRGAIPYALSLHLDLEPMEKRQLIGTTTIVIVLFTILLLGGSTMPLIRLMDIEDAK
AHRRNKKDVNLSKTEKMGNTVESEHLSELTEEEYEAHYIRRQDLKGFVWLDAKYLNPFFT
RRLTQEDLHHGRIQMKTLTNKWYEEVRQGPSGSEDDEQELL

Sequence length

581

Interactions

View interactions

	Reactome
			Sodium/Proton exchangers

Associated diseases

Show/Hide Causal Diseases (2)

Causal
Disease name	Disease term	dbSNP ID	References
Multiple sclerosis	Multiple Sclerosis	rs104895219, rs483353022, rs483353023, rs483353028, rs483353029, rs483353024, rs483353030, rs3207617, rs483353031, rs483353032, rs483353033, rs483353034, rs483353035, rs483353036, rs483353039, rs483353038, rs61731956, rs568165874, rs767480544	24076602
Psoriasis	Psoriasis	rs281875215, rs587777763, rs281875213, rs281875212	26974007

Show/Hide Unknown Diseases (6)

Unknown
Disease name	Disease term	dbSNP ID	References
Ankylosing spondylitis	Ankylosing spondylitis		26974007
Cholangitis	Cholangitis, Sclerosing		26974007
Crohn disease	Crohn Disease	rs2066847, rs2066844, rs886052047, rs5743265, rs111608429, rs104895438	26974007
Dementia	Dementia, Familial Dementia		19234771
Senile paranoid dementia	Senile Paranoid Dementia		19234771
Ulcerative colitis	Ulcerative Colitis		26974007

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