GeDiPNet: Comprehensive Gene Data - OMIM, HGNC, Ensembl, UniProt, GO, Transcription Factors & miRNA

Home
Browse
- Genes
- Diseases
- Pathways
  - Reactome
  - KEGG
Analysis
Help
Links
FAQ
Contact us

DNMBP (dynamin binding protein)

Gene

Dynamin binding protein

DNMBP

ARHGEF36, CTRCT48, TUBA

10

10q24.2

This gene encodes a protein belonging to the guanine nucleotide exchange factor family, and which regulates the configuration of cell junctions. It contains multiple binding sites for dynamin and thus links dynamin to actin regulatory proteins. Polymorphi

Show/Hide all(2)

SNP ID	Visualize variation	Clinical significance	Consequence
rs1564722302	CT>-	Pathogenic	Stop gained, coding sequence variant
rs1564723150	GGTT>-	Pathogenic	Frameshift variant, coding sequence variant

Show/Hide all(363)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016851	hsa-miR-335-5p	Microarray	18185580
MIRT022215	hsa-miR-124-3p	Microarray	18668037
MIRT028856	hsa-miR-26b-5p	Microarray	19088304
MIRT052230	hsa-let-7b-5p	CLASH	23622248
MIRT050939	hsa-miR-17-5p	CLASH	23622248
MIRT046341	hsa-miR-23b-3p	CLASH	23622248
MIRT039020	hsa-miR-766-3p	CLASH	23622248
MIRT641150	hsa-miR-3120-3p	HITS-CLIP	23824327
MIRT641149	hsa-miR-3675-5p	HITS-CLIP	23824327
MIRT641148	hsa-miR-3678-5p	HITS-CLIP	23824327
MIRT641147	hsa-miR-6762-5p	HITS-CLIP	23824327
MIRT641146	hsa-miR-6845-5p	HITS-CLIP	23824327
MIRT641145	hsa-miR-128-1-5p	HITS-CLIP	23824327
MIRT641144	hsa-miR-128-2-5p	HITS-CLIP	23824327
MIRT260871	hsa-miR-1227-5p	HITS-CLIP	23824327
MIRT727863	hsa-miR-26a-5p	HITS-CLIP	22473208
MIRT028856	hsa-miR-26b-5p	HITS-CLIP	22473208
MIRT641150	hsa-miR-3120-3p	HITS-CLIP	23824327
MIRT641149	hsa-miR-3675-5p	HITS-CLIP	23824327
MIRT641148	hsa-miR-3678-5p	HITS-CLIP	23824327
MIRT641147	hsa-miR-6762-5p	HITS-CLIP	23824327
MIRT641146	hsa-miR-6845-5p	HITS-CLIP	23824327
MIRT641145	hsa-miR-128-1-5p	HITS-CLIP	23824327
MIRT641144	hsa-miR-128-2-5p	HITS-CLIP	23824327
MIRT260871	hsa-miR-1227-5p	HITS-CLIP	23824327
MIRT942440	hsa-miR-1	CLIP-seq
MIRT942441	hsa-miR-1225-3p	CLIP-seq
MIRT942442	hsa-miR-1233	CLIP-seq
MIRT942443	hsa-miR-1255a	CLIP-seq
MIRT942444	hsa-miR-1255b	CLIP-seq
MIRT942445	hsa-miR-1273e	CLIP-seq
MIRT942446	hsa-miR-1297	CLIP-seq
MIRT942447	hsa-miR-1299	CLIP-seq
MIRT942448	hsa-miR-135a	CLIP-seq
MIRT942449	hsa-miR-135b	CLIP-seq
MIRT942450	hsa-miR-153	CLIP-seq
MIRT942451	hsa-miR-1915	CLIP-seq
MIRT942452	hsa-miR-206	CLIP-seq
MIRT942453	hsa-miR-224	CLIP-seq
MIRT942454	hsa-miR-2276	CLIP-seq
MIRT942455	hsa-miR-26a	CLIP-seq
MIRT942456	hsa-miR-26b	CLIP-seq
MIRT942457	hsa-miR-296-3p	CLIP-seq
MIRT942458	hsa-miR-3129-3p	CLIP-seq
MIRT942459	hsa-miR-3174	CLIP-seq
MIRT942460	hsa-miR-3185	CLIP-seq
MIRT942461	hsa-miR-3192	CLIP-seq
MIRT942462	hsa-miR-345	CLIP-seq
MIRT942463	hsa-miR-3617	CLIP-seq
MIRT942464	hsa-miR-3671	CLIP-seq
MIRT942465	hsa-miR-3673	CLIP-seq
MIRT942466	hsa-miR-3682-5p	CLIP-seq
MIRT942467	hsa-miR-3714	CLIP-seq
MIRT942468	hsa-miR-378g	CLIP-seq
MIRT942469	hsa-miR-3934	CLIP-seq
MIRT942470	hsa-miR-4256	CLIP-seq
MIRT942471	hsa-miR-4279	CLIP-seq
MIRT942472	hsa-miR-4314	CLIP-seq
MIRT942473	hsa-miR-4323	CLIP-seq
MIRT942474	hsa-miR-4452	CLIP-seq
MIRT942475	hsa-miR-4465	CLIP-seq
MIRT942476	hsa-miR-448	CLIP-seq
MIRT942477	hsa-miR-4505	CLIP-seq
MIRT942478	hsa-miR-450b-5p	CLIP-seq
MIRT942479	hsa-miR-4646-5p	CLIP-seq
MIRT942480	hsa-miR-4694-5p	CLIP-seq
MIRT942481	hsa-miR-4708-3p	CLIP-seq
MIRT942482	hsa-miR-4728-5p	CLIP-seq
MIRT942483	hsa-miR-4733-5p	CLIP-seq
MIRT942484	hsa-miR-4766-5p	CLIP-seq
MIRT942485	hsa-miR-4777-5p	CLIP-seq
MIRT942486	hsa-miR-4781-3p	CLIP-seq
MIRT942487	hsa-miR-4782-5p	CLIP-seq
MIRT942488	hsa-miR-507	CLIP-seq
MIRT942489	hsa-miR-513a-5p	CLIP-seq
MIRT942490	hsa-miR-516b	CLIP-seq
MIRT942491	hsa-miR-518a-5p	CLIP-seq
MIRT942492	hsa-miR-518d-5p	CLIP-seq
MIRT942493	hsa-miR-519b-5p	CLIP-seq
MIRT942494	hsa-miR-519c-5p	CLIP-seq
MIRT942495	hsa-miR-520c-5p	CLIP-seq
MIRT942496	hsa-miR-526a	CLIP-seq
MIRT942497	hsa-miR-527	CLIP-seq
MIRT942498	hsa-miR-548an	CLIP-seq
MIRT942499	hsa-miR-552	CLIP-seq
MIRT942500	hsa-miR-557	CLIP-seq
MIRT942501	hsa-miR-579	CLIP-seq
MIRT942502	hsa-miR-607	CLIP-seq
MIRT942503	hsa-miR-613	CLIP-seq
MIRT942504	hsa-miR-636	CLIP-seq
MIRT942505	hsa-miR-641	CLIP-seq
MIRT942506	hsa-miR-875-3p	CLIP-seq
MIRT942507	hsa-miR-885-5p	CLIP-seq
MIRT942508	hsa-miR-921	CLIP-seq
MIRT1979022	hsa-miR-103b	CLIP-seq
MIRT1979023	hsa-miR-1200	CLIP-seq
MIRT1979024	hsa-miR-1207-5p	CLIP-seq
MIRT1979025	hsa-miR-1266	CLIP-seq
MIRT1979026	hsa-miR-1285	CLIP-seq
MIRT1979027	hsa-miR-1909	CLIP-seq
MIRT1979028	hsa-miR-202	CLIP-seq
MIRT1979029	hsa-miR-2110	CLIP-seq
MIRT1979030	hsa-miR-214	CLIP-seq
MIRT1979031	hsa-miR-216a	CLIP-seq
MIRT1979032	hsa-miR-216b	CLIP-seq
MIRT942454	hsa-miR-2276	CLIP-seq
MIRT942458	hsa-miR-3129-3p	CLIP-seq
MIRT1979033	hsa-miR-3156-5p	CLIP-seq
MIRT1979034	hsa-miR-3187-5p	CLIP-seq
MIRT942461	hsa-miR-3192	CLIP-seq
MIRT942462	hsa-miR-345	CLIP-seq
MIRT1979035	hsa-miR-3619-5p	CLIP-seq
MIRT1979036	hsa-miR-3664-3p	CLIP-seq
MIRT1979037	hsa-miR-3667-5p	CLIP-seq
MIRT1979038	hsa-miR-3672	CLIP-seq
MIRT1979039	hsa-miR-3689a-3p	CLIP-seq
MIRT1979040	hsa-miR-3689c	CLIP-seq
MIRT1979041	hsa-miR-376a	CLIP-seq
MIRT1979042	hsa-miR-376b	CLIP-seq
MIRT942468	hsa-miR-378g	CLIP-seq
MIRT1979043	hsa-miR-3936	CLIP-seq
MIRT942470	hsa-miR-4256	CLIP-seq
MIRT1979044	hsa-miR-4271	CLIP-seq
MIRT1979045	hsa-miR-4291	CLIP-seq
MIRT1979046	hsa-miR-4324	CLIP-seq
MIRT1979047	hsa-miR-4329	CLIP-seq
MIRT1979048	hsa-miR-4433	CLIP-seq
MIRT1979049	hsa-miR-4436b-3p	CLIP-seq
MIRT1979050	hsa-miR-4459	CLIP-seq
MIRT1979051	hsa-miR-4463	CLIP-seq
MIRT942478	hsa-miR-450b-5p	CLIP-seq
MIRT1979052	hsa-miR-4518	CLIP-seq
MIRT1979053	hsa-miR-451b	CLIP-seq
MIRT1979054	hsa-miR-4521	CLIP-seq
MIRT1979055	hsa-miR-4667-5p	CLIP-seq
MIRT1979056	hsa-miR-4685-5p	CLIP-seq
MIRT1979057	hsa-miR-4690-5p	CLIP-seq
MIRT1979058	hsa-miR-4696	CLIP-seq
MIRT1979059	hsa-miR-4700-5p	CLIP-seq
MIRT1979060	hsa-miR-4711-3p	CLIP-seq
MIRT1979061	hsa-miR-4725-3p	CLIP-seq
MIRT942482	hsa-miR-4728-5p	CLIP-seq
MIRT1979062	hsa-miR-4731-5p	CLIP-seq
MIRT1979063	hsa-miR-4763-3p	CLIP-seq
MIRT1979064	hsa-miR-4768-3p	CLIP-seq
MIRT1979065	hsa-miR-544b	CLIP-seq
MIRT1979066	hsa-miR-555	CLIP-seq
MIRT1979067	hsa-miR-601	CLIP-seq
MIRT1979068	hsa-miR-612	CLIP-seq
MIRT1979069	hsa-miR-661	CLIP-seq
MIRT1979070	hsa-miR-761	CLIP-seq
MIRT1979071	hsa-miR-922	CLIP-seq
MIRT1979022	hsa-miR-103b	CLIP-seq
MIRT2214177	hsa-miR-1237	CLIP-seq
MIRT942443	hsa-miR-1255a	CLIP-seq
MIRT942444	hsa-miR-1255b	CLIP-seq
MIRT1979026	hsa-miR-1285	CLIP-seq
MIRT2214178	hsa-miR-149	CLIP-seq
MIRT942450	hsa-miR-153	CLIP-seq
MIRT942451	hsa-miR-1915	CLIP-seq
MIRT1979028	hsa-miR-202	CLIP-seq
MIRT1979029	hsa-miR-2110	CLIP-seq
MIRT942453	hsa-miR-224	CLIP-seq
MIRT942454	hsa-miR-2276	CLIP-seq
MIRT2214179	hsa-miR-3064-5p	CLIP-seq
MIRT2214180	hsa-miR-3119	CLIP-seq
MIRT2214181	hsa-miR-3126-3p	CLIP-seq
MIRT942458	hsa-miR-3129-3p	CLIP-seq
MIRT1979033	hsa-miR-3156-5p	CLIP-seq
MIRT942460	hsa-miR-3185	CLIP-seq
MIRT1979034	hsa-miR-3187-5p	CLIP-seq
MIRT942461	hsa-miR-3192	CLIP-seq
MIRT2214182	hsa-miR-33a	CLIP-seq
MIRT2214183	hsa-miR-33b	CLIP-seq
MIRT942462	hsa-miR-345	CLIP-seq
MIRT2214184	hsa-miR-3614-5p	CLIP-seq
MIRT942463	hsa-miR-3617	CLIP-seq
MIRT1979037	hsa-miR-3667-5p	CLIP-seq
MIRT942464	hsa-miR-3671	CLIP-seq
MIRT1979038	hsa-miR-3672	CLIP-seq
MIRT942466	hsa-miR-3682-5p	CLIP-seq
MIRT1979039	hsa-miR-3689a-3p	CLIP-seq
MIRT1979040	hsa-miR-3689c	CLIP-seq
MIRT2214185	hsa-miR-371-5p	CLIP-seq
MIRT2214186	hsa-miR-371b-5p	CLIP-seq
MIRT1979041	hsa-miR-376a	CLIP-seq
MIRT1979042	hsa-miR-376b	CLIP-seq
MIRT942468	hsa-miR-378g	CLIP-seq
MIRT2214187	hsa-miR-383	CLIP-seq
MIRT2214188	hsa-miR-3921	CLIP-seq
MIRT2214189	hsa-miR-3924	CLIP-seq
MIRT2214190	hsa-miR-412	CLIP-seq
MIRT942470	hsa-miR-4256	CLIP-seq
MIRT2214191	hsa-miR-4269	CLIP-seq
MIRT1979044	hsa-miR-4271	CLIP-seq
MIRT2214192	hsa-miR-4278	CLIP-seq
MIRT2214193	hsa-miR-4297	CLIP-seq
MIRT942473	hsa-miR-4323	CLIP-seq
MIRT942474	hsa-miR-4452	CLIP-seq
MIRT1979051	hsa-miR-4463	CLIP-seq
MIRT942476	hsa-miR-448	CLIP-seq
MIRT942478	hsa-miR-450b-5p	CLIP-seq
MIRT2214194	hsa-miR-4514	CLIP-seq
MIRT1979053	hsa-miR-451b	CLIP-seq
MIRT2214195	hsa-miR-4653-5p	CLIP-seq
MIRT1979055	hsa-miR-4667-5p	CLIP-seq
MIRT2214196	hsa-miR-4688	CLIP-seq
MIRT2214197	hsa-miR-4692	CLIP-seq
MIRT1979058	hsa-miR-4696	CLIP-seq
MIRT1979059	hsa-miR-4700-5p	CLIP-seq
MIRT2214198	hsa-miR-4719	CLIP-seq
MIRT1979061	hsa-miR-4725-3p	CLIP-seq
MIRT942482	hsa-miR-4728-5p	CLIP-seq
MIRT1979062	hsa-miR-4731-5p	CLIP-seq
MIRT2214199	hsa-miR-4742-5p	CLIP-seq
MIRT2214200	hsa-miR-4772-5p	CLIP-seq
MIRT942485	hsa-miR-4777-5p	CLIP-seq
MIRT2214201	hsa-miR-4794	CLIP-seq
MIRT2214202	hsa-miR-486-3p	CLIP-seq
MIRT942488	hsa-miR-507	CLIP-seq
MIRT2214203	hsa-miR-513b	CLIP-seq
MIRT942491	hsa-miR-518a-5p	CLIP-seq
MIRT942492	hsa-miR-518d-5p	CLIP-seq
MIRT942493	hsa-miR-519b-5p	CLIP-seq
MIRT942494	hsa-miR-519c-5p	CLIP-seq
MIRT942495	hsa-miR-520c-5p	CLIP-seq
MIRT942496	hsa-miR-526a	CLIP-seq
MIRT942497	hsa-miR-527	CLIP-seq
MIRT942500	hsa-miR-557	CLIP-seq
MIRT942501	hsa-miR-579	CLIP-seq
MIRT2214204	hsa-miR-582-3p	CLIP-seq
MIRT942502	hsa-miR-607	CLIP-seq
MIRT1979068	hsa-miR-612	CLIP-seq
MIRT942504	hsa-miR-636	CLIP-seq
MIRT942505	hsa-miR-641	CLIP-seq
MIRT1979069	hsa-miR-661	CLIP-seq
MIRT942507	hsa-miR-885-5p	CLIP-seq
MIRT1979024	hsa-miR-1207-5p	CLIP-seq
MIRT2387050	hsa-miR-1293	CLIP-seq
MIRT2214178	hsa-miR-149	CLIP-seq
MIRT942451	hsa-miR-1915	CLIP-seq
MIRT1979028	hsa-miR-202	CLIP-seq
MIRT2214179	hsa-miR-3064-5p	CLIP-seq
MIRT2214180	hsa-miR-3119	CLIP-seq
MIRT2214181	hsa-miR-3126-3p	CLIP-seq
MIRT942461	hsa-miR-3192	CLIP-seq
MIRT2214184	hsa-miR-3614-5p	CLIP-seq
MIRT2387051	hsa-miR-3657	CLIP-seq
MIRT1979039	hsa-miR-3689a-3p	CLIP-seq
MIRT1979040	hsa-miR-3689c	CLIP-seq
MIRT2387052	hsa-miR-3689d	CLIP-seq
MIRT942467	hsa-miR-3714	CLIP-seq
MIRT2387053	hsa-miR-376c	CLIP-seq
MIRT2214187	hsa-miR-383	CLIP-seq
MIRT2214191	hsa-miR-4269	CLIP-seq
MIRT2387054	hsa-miR-4483	CLIP-seq
MIRT942477	hsa-miR-4505	CLIP-seq
MIRT2214194	hsa-miR-4514	CLIP-seq
MIRT2214197	hsa-miR-4692	CLIP-seq
MIRT942481	hsa-miR-4708-3p	CLIP-seq
MIRT942482	hsa-miR-4728-5p	CLIP-seq
MIRT2387055	hsa-miR-4736	CLIP-seq
MIRT2214199	hsa-miR-4742-5p	CLIP-seq
MIRT1979063	hsa-miR-4763-3p	CLIP-seq
MIRT2214200	hsa-miR-4772-5p	CLIP-seq
MIRT2214201	hsa-miR-4794	CLIP-seq
MIRT942498	hsa-miR-548an	CLIP-seq
MIRT1979026	hsa-miR-1285	CLIP-seq
MIRT1979034	hsa-miR-3187-5p	CLIP-seq
MIRT1979037	hsa-miR-3667-5p	CLIP-seq
MIRT1979053	hsa-miR-451b	CLIP-seq
MIRT1979058	hsa-miR-4696	CLIP-seq
MIRT1979068	hsa-miR-612	CLIP-seq
MIRT1979069	hsa-miR-661	CLIP-seq
MIRT1979026	hsa-miR-1285	CLIP-seq
MIRT1979034	hsa-miR-3187-5p	CLIP-seq
MIRT1979037	hsa-miR-3667-5p	CLIP-seq
MIRT1979053	hsa-miR-451b	CLIP-seq
MIRT1979058	hsa-miR-4696	CLIP-seq
MIRT1979068	hsa-miR-612	CLIP-seq
MIRT1979069	hsa-miR-661	CLIP-seq
MIRT942441	hsa-miR-1225-3p	CLIP-seq
MIRT942442	hsa-miR-1233	CLIP-seq
MIRT942445	hsa-miR-1273e	CLIP-seq
MIRT1979026	hsa-miR-1285	CLIP-seq
MIRT2518549	hsa-miR-1321	CLIP-seq
MIRT2518550	hsa-miR-208a	CLIP-seq
MIRT2518551	hsa-miR-208b	CLIP-seq
MIRT1979030	hsa-miR-214	CLIP-seq
MIRT1979031	hsa-miR-216a	CLIP-seq
MIRT1979032	hsa-miR-216b	CLIP-seq
MIRT942457	hsa-miR-296-3p	CLIP-seq
MIRT1979033	hsa-miR-3156-5p	CLIP-seq
MIRT1979034	hsa-miR-3187-5p	CLIP-seq
MIRT2518552	hsa-miR-3613-3p	CLIP-seq
MIRT1979035	hsa-miR-3619-5p	CLIP-seq
MIRT2518553	hsa-miR-3650	CLIP-seq
MIRT2518554	hsa-miR-3658	CLIP-seq
MIRT1979037	hsa-miR-3667-5p	CLIP-seq
MIRT2214185	hsa-miR-371-5p	CLIP-seq
MIRT2214186	hsa-miR-371b-5p	CLIP-seq
MIRT2518555	hsa-miR-4270	CLIP-seq
MIRT1979045	hsa-miR-4291	CLIP-seq
MIRT2518556	hsa-miR-4441	CLIP-seq
MIRT1979053	hsa-miR-451b	CLIP-seq
MIRT1979058	hsa-miR-4696	CLIP-seq
MIRT942482	hsa-miR-4728-5p	CLIP-seq
MIRT2518557	hsa-miR-4739	CLIP-seq
MIRT2214199	hsa-miR-4742-5p	CLIP-seq
MIRT2518558	hsa-miR-4756-5p	CLIP-seq
MIRT2518559	hsa-miR-499-5p	CLIP-seq
MIRT1979068	hsa-miR-612	CLIP-seq
MIRT1979069	hsa-miR-661	CLIP-seq
MIRT1979070	hsa-miR-761	CLIP-seq
MIRT1979071	hsa-miR-922	CLIP-seq
MIRT942441	hsa-miR-1225-3p	CLIP-seq
MIRT942442	hsa-miR-1233	CLIP-seq
MIRT942445	hsa-miR-1273e	CLIP-seq
MIRT1979026	hsa-miR-1285	CLIP-seq
MIRT2518549	hsa-miR-1321	CLIP-seq
MIRT1979028	hsa-miR-202	CLIP-seq
MIRT2518550	hsa-miR-208a	CLIP-seq
MIRT2518551	hsa-miR-208b	CLIP-seq
MIRT1979030	hsa-miR-214	CLIP-seq
MIRT1979031	hsa-miR-216a	CLIP-seq
MIRT1979032	hsa-miR-216b	CLIP-seq
MIRT942457	hsa-miR-296-3p	CLIP-seq
MIRT1979033	hsa-miR-3156-5p	CLIP-seq
MIRT1979034	hsa-miR-3187-5p	CLIP-seq
MIRT942461	hsa-miR-3192	CLIP-seq
MIRT2518552	hsa-miR-3613-3p	CLIP-seq
MIRT1979035	hsa-miR-3619-5p	CLIP-seq
MIRT2518553	hsa-miR-3650	CLIP-seq
MIRT2518554	hsa-miR-3658	CLIP-seq
MIRT1979037	hsa-miR-3667-5p	CLIP-seq
MIRT1979038	hsa-miR-3672	CLIP-seq
MIRT1979039	hsa-miR-3689a-3p	CLIP-seq
MIRT1979040	hsa-miR-3689c	CLIP-seq
MIRT2214185	hsa-miR-371-5p	CLIP-seq
MIRT2214186	hsa-miR-371b-5p	CLIP-seq
MIRT2214187	hsa-miR-383	CLIP-seq
MIRT2214191	hsa-miR-4269	CLIP-seq
MIRT2518555	hsa-miR-4270	CLIP-seq
MIRT1979045	hsa-miR-4291	CLIP-seq
MIRT2518556	hsa-miR-4441	CLIP-seq
MIRT1979051	hsa-miR-4463	CLIP-seq
MIRT2679375	hsa-miR-4464	CLIP-seq
MIRT2214194	hsa-miR-4514	CLIP-seq
MIRT1979053	hsa-miR-451b	CLIP-seq
MIRT2214197	hsa-miR-4692	CLIP-seq
MIRT1979058	hsa-miR-4696	CLIP-seq
MIRT942482	hsa-miR-4728-5p	CLIP-seq
MIRT2518557	hsa-miR-4739	CLIP-seq
MIRT2214199	hsa-miR-4742-5p	CLIP-seq
MIRT2679376	hsa-miR-4748	CLIP-seq
MIRT2518558	hsa-miR-4756-5p	CLIP-seq
MIRT2214200	hsa-miR-4772-5p	CLIP-seq
MIRT2518559	hsa-miR-499-5p	CLIP-seq
MIRT1979068	hsa-miR-612	CLIP-seq
MIRT2679377	hsa-miR-659	CLIP-seq
MIRT1979069	hsa-miR-661	CLIP-seq
MIRT1979070	hsa-miR-761	CLIP-seq
MIRT1979071	hsa-miR-922	CLIP-seq

Show/Hide all(12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IDA	17015620
GO:0005515	Function	Protein binding	IPI	16413298, 17015620, 18654987
GO:0005794	Component	Golgi apparatus	ISS
GO:0005795	Component	Golgi stack	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005911	Component	Cell-cell junction	IDA	17015620
GO:0007568	Process	Aging	IEA
GO:0008360	Process	Regulation of cell shape	IMP	17015620
GO:0035556	Process	Intracellular signal transduction	IEA
GO:0045202	Component	Synapse	ISS
GO:0050790	Process	Regulation of catalytic activity	IEA
GO:0098793	Component	Presynapse	ISS

MIM	HGNC	e!Ensembl
611282	30373	ENSG00000107554

Protein

UniProt ID

Protein name

Dynamin-binding protein (Scaffold protein Tuba)

Protein function

Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in

PDB

1UG1 , 1UHC , 4CC2 , 4CC3 , 4CC4 , 4CC7 , 4GLM

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00018	SH3_1	8 → 53	SH3 domain	Domain
PF07653	SH3_2	70 → 124	Variant SH3 domain	Domain
PF14604	SH3_9	152 → 200	Variant SH3 domain	Domain
PF00018	SH3_1	249 → 294	SH3 domain	Domain
PF00621	RhoGEF	788 → 965	RhoGEF domain	Domain
PF03114	BAR	997 → 1209	BAR domain	Domain
PF00018	SH3_1	1519 → 1568	SH3 domain	Domain

Sequence

MEAGSVVRAIFDFCPSVSEELPLFVGDIIEVLAVVDEFWLLGKKEDVTGQFPSSFVEIVT
IPSLKEGERLFVCICEFTSQELDNLPLHRGDLVILDGIPTAGWLQGRSCWGARGFFPSSC
VRELCLSSQSRQWHSQSALFQIPEYSMGQARALMGLSAQLDEELDFREGDVITIIGVPEP
GWFEGELEGRRGIFPEGFVELLGPLRTVDESVSSGNQDDCIVNGEVDTPVGEEEIGPDED
EEEPGTYGVALYRFQALEPNELDFEVGDKIRILATLEDGWLEGSLKGRTGIFPYRFVKLC
PDTRVEETMALPQEGSLARIPETSLDCLENTLGVEEQRHETSDHEAEEPDCIISEAPTSP
LGHLTSEYDTDRNSYQDEDTAGGPPRSPGVEWEMPLATDSPTSDPTEVVNGISSQPQVPF
HPNLQKSQYYSTVGGSHPHSEQYPDLLPLEARTRDYASLPPKRMYSQLKTLQKPVLPLYR
GSSVSASRVVKPRQSSPQLHNLASYTKKHHTSSVYSISERLEMKPGPQAQGLVMEAATHS
QGDGSTDLDSKLTQQLIEFEKSLAGPGTEPDKILRHFSIMDFNSEKDIVRGSSKLITEQE
LPERRKALRPPPPRPCTPVSTSPHLLVDQNLKPAPPLVVRPSRPAPLPPSAQQRTNAVSP
KLLSRHRPTCETLEKEGPGHMGRSLDQTSPCPLVLVRIEEMERDLDMYSRAQEELNLMLE
EKQDESSRAETLEDLKFCESNIESLNMELQQLREMTLLSSQSSSLVAPSGSVSAENPEQR
MLEKRAKVIEELLQTERDYIRDLEMCIERIMVPMQQAQVPNIDFEGLFGNMQMVIKVSKQ
LLAALEISDAVGPVFLGHRDELEGTYKIYCQNHDEAIALLEIYEKDEKIQKHLQDSLADL
KSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELLNSTPESHPDKVPLTNAVLAVKEI
NVNINEYKRRKDLVLKYRKGDEDSLMEKISKLNIHSIIKKSNRVSSHLKHLTGFAPQIKD
EVFEETEKNFRMQERLIKSFIRDLSLYLQHIRESACVKVVAAVSMWDVCMERGHRDLEQF
ERVHRYISDQLFTNFKERTERLVISPLNQLLSMFTGPHKLVQKRFDKLLDFYNCTERAEK
LKDKKTLEELQSARNNYEALNAQLLDELPKFHQYAQGLFTNCVHGYAEAHCDFVHQALEQ
LKPLLSLLKVAGREGNLIAIFHEEHSRVLQQLQVFTFFPESLPATKKPFERKTIDRQSAR
KPLLGLPSYMLQSEELRASLLARYPPEKLFQAERNFNAAQDLDVSLLEGDLVGVIKKKDP
MGSQNRWLIDNGVTKGFVYSSFLKPYNPRRSHSDASVGSHSSTESEHGSSSPRFPRQNSG
STLTFNPSSMAVSFTSGSCQKQPQDASPPPKECDQGTLSASLNPSNSESSPSRCPSDPDS
TSQPRSGDSADVARDVKQPTATPRSYRNFRHPEIVGYSVPGRNGQSQDLVKGCARTAQAP
EDRSTEPDGSEAEGNQVYFAVYTFKARNPNELSVSANQKLKILEFKDVTGNTEWWLAEVN
GKKGYVPSNYIRKTEYT

Sequence length

1577

Interactions

View interactions

Associated diseases

Show/Hide Causal Diseases (1)

Causal
Disease name	Disease term	dbSNP ID	References
Cataract	Total early-onset cataract	rs118203965, rs118203966, rs104893685, rs121908938, rs104894175, rs121909048, rs28937573, rs121909049, rs121909050, rs74315488, rs80358200, rs80358203, rs121434643, rs56141211, rs132630322, rs121917775, rs121917735, rs121917736, rs137853199, rs137853200, rs121917867, rs121917869, rs121913555, rs104893736, rs121909595, rs121909596, rs121909597, rs28931605, rs121909598, rs104893618, rs1695062782, rs74315486, rs74315487, rs74315490, rs74315489, rs745938679, rs1566402656, rs74315439, rs74315441, rs121912973, rs121917823, rs1593332981, rs121917825, rs121917827, rs113994108, rs387906963, rs387906964, rs1240503246, rs387906965, rs387906966, rs750207077, rs387907336, rs387907337, rs387907342, rs140332366, rs397514703, rs398122937, rs398122378, rs398122392, rs398122944, rs137853924, rs398122947, rs397515623, rs397515624, rs397515625, rs397515626, rs398122948, rs587778872, rs398123066, rs587777601, rs370424081, rs786205221, rs786205222, rs864309684, rs864309688, rs864309701, rs864309689, rs864309690, rs864309681, rs864309686, rs864309696, rs864309693, rs864309687, rs864309691, rs864309692, rs864309695, rs864309678, rs864309685, rs864309700, rs864309698, rs864309683, rs864309682, rs864309679, rs111534978, rs864309680, rs864309702, rs864622780, rs756898971, rs869312732, rs775038545, rs878852983, rs1114167312, rs1114167313, rs1114167314, rs1114167315, rs1114167307, rs886041410, rs886041412, rs1057518738, rs1057517926, rs1057518878, rs1057519616, rs12799308, rs1064793935, rs1064797219, rs1085307126, rs1085307127, rs765628635, rs1114167427, rs1114167433, rs1554744860, rs1554743428, rs747093432, rs1411557416, rs1555179713, rs1481963503, rs1555549755, rs1456161420, rs1555547008, rs1555889308, rs1555888762, rs766522434, rs1264025914, rs1553585262, rs1567671947, rs1337897299, rs764945940, rs1307969607, rs949335475, rs1184095219, rs776129797, rs1569203234, rs1567668570, rs749141857, rs764098604, rs1184398243, rs1578956689, rs1568480054, rs1564745688, rs1564722302, rs1564723150, rs1571175950, rs1569602837, rs1576552712, rs1575369255, rs981126461, rs1570403798, rs200557771, rs1477743112, rs1651879427, rs1651881222, rs1651919374, rs2024441691, rs148284531, rs1246080692

Show/Hide Unknown Diseases (4)

Unknown
Disease name	Disease term	dbSNP ID	References
Congenital cataract	Congenital total cataract		30290152
Exotropia	Exotropia
Miosis disorder	Miosis disorder
Pendular nystagmus	Pendular Nystagmus

| © 2021, Biomedical Informatics Centre, NIRRH |
ICMR-National Institute for Research in Reproductive Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Tel: +91-22-24192104, Fax No: +91-22-24139412