Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
23235 |
Gene nameGene Name - the full gene name approved by the HGNC.
|
Salt inducible kinase 2 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
SIK2 |
SynonymsGene synonyms aliases
|
LOH11CR1I, QIK, SIK-2, SNF1LK2 |
ChromosomeChromosome number
|
11 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
11q23.1 |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
|
UniProt ID |
Q9H0K1 |
Protein name |
Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2) |
Protein function |
Serine/threonine-protein kinase that plays a role in many biological processes such as fatty acid oxidation, autophagy, immune response or glucose metabolism (PubMed:23322770, PubMed:26983400). Phosphorylates 'Ser-794' of IRS1 in insulin-stimula |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00069 |
Pkinase |
20 → 271 |
Protein kinase domain |
Domain |
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Sequence |
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Sequence length |
926 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
|
|
Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Cholangitis |
Cholangitis, Sclerosing |
|
27992413, 23603763 |
Sclerosing cholangitis |
Primary sclerosing cholangitis |
|
23603763 |
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