ZFR2 (zinc finger RNA binding protein 2)

Gene

• Entrez ID: 23217
• Gene name: Zinc finger RNA binding protein 2
• Gene symbol: ZFR2
• Synonyms: KIAA1086
• Chromosome: 19
• Chromosome location: 19p13.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT519081	hsa-miR-1911-3p	PAR-CLIP	23446348
MIRT519080	hsa-miR-4716-5p	PAR-CLIP	23446348
MIRT519079	hsa-miR-197-3p	PAR-CLIP	23446348
MIRT461148	hsa-miR-6886-5p	PAR-CLIP	23592263
MIRT461147	hsa-miR-3665	PAR-CLIP	23592263
MIRT519081	hsa-miR-1911-3p	PAR-CLIP	23446348
MIRT519080	hsa-miR-4716-5p	PAR-CLIP	23446348
MIRT519079	hsa-miR-197-3p	PAR-CLIP	23446348
MIRT461148	hsa-miR-6886-5p	PAR-CLIP	23592263
MIRT461147	hsa-miR-3665	PAR-CLIP	23592263
MIRT1512018	hsa-miR-1207-3p	CLIP-seq
MIRT1512019	hsa-miR-2861	CLIP-seq
MIRT1512020	hsa-miR-3165	CLIP-seq
MIRT1512021	hsa-miR-3650	CLIP-seq
MIRT1512022	hsa-miR-3689d	CLIP-seq
MIRT1512023	hsa-miR-4456	CLIP-seq
MIRT1512024	hsa-miR-4501	CLIP-seq
MIRT1512025	hsa-miR-4504	CLIP-seq
MIRT1512026	hsa-miR-541	CLIP-seq
MIRT1512027	hsa-miR-542-3p	CLIP-seq
MIRT1512028	hsa-miR-654-5p	CLIP-seq
MIRT1512029	hsa-let-7a	CLIP-seq
MIRT1512030	hsa-let-7b	CLIP-seq
MIRT1512031	hsa-let-7c	CLIP-seq
MIRT1512032	hsa-let-7d	CLIP-seq
MIRT1512033	hsa-let-7e	CLIP-seq
MIRT1512034	hsa-let-7f	CLIP-seq
MIRT1512035	hsa-let-7g	CLIP-seq
MIRT1512036	hsa-let-7i	CLIP-seq
MIRT1512037	hsa-miR-106a	CLIP-seq
MIRT1512038	hsa-miR-106b	CLIP-seq
MIRT1512039	hsa-miR-1182	CLIP-seq
MIRT1512040	hsa-miR-1234	CLIP-seq
MIRT1512041	hsa-miR-1273d	CLIP-seq
MIRT1512042	hsa-miR-1275	CLIP-seq
MIRT1512043	hsa-miR-17	CLIP-seq
MIRT1512044	hsa-miR-20a	CLIP-seq
MIRT1512045	hsa-miR-20b	CLIP-seq
MIRT1512046	hsa-miR-302a	CLIP-seq
MIRT1512047	hsa-miR-302b	CLIP-seq
MIRT1512048	hsa-miR-302c	CLIP-seq
MIRT1512049	hsa-miR-302d	CLIP-seq
MIRT1512050	hsa-miR-302e	CLIP-seq
MIRT1512051	hsa-miR-3607-3p	CLIP-seq
MIRT1512052	hsa-miR-3686	CLIP-seq
MIRT1512053	hsa-miR-371-5p	CLIP-seq
MIRT1512054	hsa-miR-371b-5p	CLIP-seq
MIRT1512055	hsa-miR-372	CLIP-seq
MIRT1512056	hsa-miR-373	CLIP-seq
MIRT1512057	hsa-miR-3973	CLIP-seq
MIRT1512058	hsa-miR-4438	CLIP-seq
MIRT1512059	hsa-miR-4447	CLIP-seq
MIRT1512060	hsa-miR-4458	CLIP-seq
MIRT1512061	hsa-miR-4472	CLIP-seq
MIRT1512062	hsa-miR-4500	CLIP-seq
MIRT1512063	hsa-miR-4525	CLIP-seq
MIRT1512064	hsa-miR-4665-5p	CLIP-seq
MIRT1512065	hsa-miR-4723-5p	CLIP-seq
MIRT1512066	hsa-miR-4731-5p	CLIP-seq
MIRT1512067	hsa-miR-4757-5p	CLIP-seq
MIRT1512068	hsa-miR-5095	CLIP-seq
MIRT1512069	hsa-miR-512-3p	CLIP-seq
MIRT1512070	hsa-miR-519d	CLIP-seq
MIRT1512071	hsa-miR-520a-3p	CLIP-seq
MIRT1512072	hsa-miR-520b	CLIP-seq
MIRT1512073	hsa-miR-520c-3p	CLIP-seq
MIRT1512074	hsa-miR-520d-3p	CLIP-seq
MIRT1512075	hsa-miR-520e	CLIP-seq
MIRT1512076	hsa-miR-520g	CLIP-seq
MIRT1512077	hsa-miR-520h	CLIP-seq
MIRT1512078	hsa-miR-625	CLIP-seq
MIRT1512079	hsa-miR-720	CLIP-seq
MIRT1512080	hsa-miR-93	CLIP-seq
MIRT1512081	hsa-miR-98	CLIP-seq
MIRT1512041	hsa-miR-1273d	CLIP-seq
MIRT2154149	hsa-miR-3199	CLIP-seq
MIRT2154150	hsa-miR-3672	CLIP-seq
MIRT2374395	hsa-miR-1271	CLIP-seq
MIRT2374396	hsa-miR-142-5p	CLIP-seq
MIRT2374397	hsa-miR-561	CLIP-seq
MIRT2374398	hsa-miR-96	CLIP-seq
MIRT2154149	hsa-miR-3199	CLIP-seq
MIRT2463959	hsa-miR-4755-3p	CLIP-seq
MIRT2463960	hsa-miR-552	CLIP-seq
MIRT2463961	hsa-miR-591	CLIP-seq
MIRT2463962	hsa-miR-764	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003725	Function	Double-stranded RNA binding	IBA	21873635
GO:0003727	Function	Single-stranded RNA binding	IBA	21873635
GO:0008270	Function	Zinc ion binding	IEA

Other IDs

• MIM: 619284
• HGNC: 29189
• e!Ensembl: ENSG00000105278

Protein

• UniProt ID: Q9UPR6
• Protein name: Zinc finger RNA-binding protein 2
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12874	zf-met	271 → 295		Domain
  PF12874	zf-met	319 → 343		Domain
  PF12874	zf-met	468 → 492		Domain
  PF07528	DZF	658 → 904	DZF domain	Domain

• Sequence:

  MATSQYFDFAQGGGPQYSAQPPTLPLPTVGASYTAQPTPGMDPAVNPAFPPAAPAGYGGY
  QPHSGQDFAYGSRPQEPVPTATTMATYQDSYSYGQSAAARSYEDRPYFQSAALQSGRMTA
  ADSGQPGTQEACGQPSPHGSHSHAQPPQQAPIVESGQPASTLSSGYTYPTATGVQPESSA
  SIVTSYPPPSYNPTCTAYTAPSYPNYDASVYSAASPFYPPAQPPPPPGPPQQLPPPPAPA
  GSGSSPRADSKPPLPSKLPRPKAGPRQLQLHYCDICKISCAGPQTYREHLGGQKHRKKEA
  AQKTGVQPNGSPRGVQAQLHCDLCAVSCTGADAYAAHIRGSKHQKVFKLHAKLGKPIPTL
  EPALATESPPGAEAKPTSPTGPSVCASSRPALAKRPVASKALCEGPPEPQAAGCRPQWGK
  PAQPKLEGPGAPTQGGSKEAPAGCSDAQPVGPEYVEEVFSDEGRVLRFHCKLCECSFNDL
  NAKDLHVRGRRHRLQYRKKVNPDLPIATEPSSRARKVLEERMRKQRHLAEERLEQLRRWH
  AERRRLEEEPPQDVPPHAPPDWAQPLLMGRPESPASAPLQPGRRPASSDDRHVMCKHATI
  YPTEQELLAVQRAVSHAERALKLVSDTLAEEDRGRREEEGDKRSSVAPQTRVLKGVMRVG
  ILAKGLLLRGDRNVRLALLCSEKPTHSLLRRIAQQLPRQLQMVTEDEYEVSSDPEANIVI
  SSCEEPRMQVTISVTSPLMREDPSTDPGVEEPQADAGDVLSPKKCLESLAALRHARWFQA
  RASGLQPCVIVIRVLRDLCRRVPTWGALPAWAMELLVEKAVSSAAGPLGPGDAVRRVLEC
  VATGTLLTDGPGLQDPCERDQTDALEPMTLQEREDVTASAQHALRMLAFRQTHKVLGMDL
  LPPRHRLGARFRKRQRGPGEGEEGAGEKKRGRRGGEGLV

• Sequence length: 939

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Obesity	Obesity	rs34911341, rs74315349, rs1474810899, rs2282440, rs2491132, rs121918111, rs796065034, rs753856820, rs796065035, rs121918112, rs104894023, rs137852821, rs1580764441, rs137852822, rs137852823, rs137852824, rs13447324, rs121913562, rs121913564, rs74315393, rs121913556, rs2989924, rs193922650, rs193922685, rs193922687, rs751160202, rs1421085, rs747681609, rs1553400259, rs13447339, rs370479598, rs1554394014, rs1553174844, rs756232889, rs369841551, rs1557670950, rs1571321748, rs148538980, rs1572820988, rs1591461970, rs1419374563, rs745921568, rs144159890, rs1570714352, rs779783209, rs1573250294, rs1573254045, rs1580744791, rs1580746829, rs6548238, rs7138803, rs7754840	29273807