FLT1 (fms related receptor tyrosine kinase 1)

Gene

• Entrez ID: 2321
• Gene name: Fms related receptor tyrosine kinase 1
• Gene symbol: FLT1
• Synonyms: FLT, FLT-1, VEGFR-1, VEGFR1
• Chromosome: 13
• Chromosome location: 13q12.3
• Summary: This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a tra

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT006441	hsa-miR-200b-3p	Luciferase reporter assay, Western blot	21544626
MIRT006441	hsa-miR-200b-3p	Luciferase reporter assay, Western blot	21544626
MIRT006441	hsa-miR-200b-3p	Luciferase reporter assay, Western blot	21544626
MIRT006850	hsa-miR-100-5p	Luciferase reporter assay	22955733
MIRT006850	hsa-miR-100-5p	Luciferase reporter assay	22955733
MIRT006885	hsa-miR-200c-3p	Luciferase reporter assay, Western blot	22569286
MIRT020776	hsa-miR-155-5p	qRT-PCR	21310411
MIRT006885	hsa-miR-200c-3p	Luciferase reporter assay, qRT-PCR, Western blot	22735571
MIRT608058	hsa-miR-8485	HITS-CLIP	23313552
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23313552
MIRT608056	hsa-miR-935	HITS-CLIP	23313552
MIRT608058	hsa-miR-8485	HITS-CLIP	23313552
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23313552
MIRT608056	hsa-miR-935	HITS-CLIP	23313552
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23313552
MIRT608058	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT608058	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT608058	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT608058	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT608058	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT608058	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT608058	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT608058	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT608058	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT608058	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT608058	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608058	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT608058	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT608058	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT608058	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT608058	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT608058	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT608058	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT608058	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT608058	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608058	hsa-miR-8485	HITS-CLIP	24906430
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	24906430
MIRT608056	hsa-miR-935	HITS-CLIP	24906430
MIRT608055	hsa-miR-582-5p	HITS-CLIP	24906430
MIRT443671	hsa-miR-371b-3p	PAR-CLIP	22100165
MIRT443670	hsa-miR-371a-3p	PAR-CLIP	22100165
MIRT443669	hsa-miR-33b-3p	PAR-CLIP	22100165
MIRT443668	hsa-miR-515-3p	PAR-CLIP	22100165
MIRT443667	hsa-miR-519e-3p	PAR-CLIP	22100165
MIRT443666	hsa-miR-5189-3p	PAR-CLIP	22100165
MIRT443664	hsa-miR-4671-3p	PAR-CLIP	22100165
MIRT443665	hsa-miR-4473	PAR-CLIP	22100165
MIRT443663	hsa-miR-6844	PAR-CLIP	22100165
MIRT006441	hsa-miR-200b-3p	Western blot	27373709
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	27418678
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	27418678
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	27418678
MIRT575422	hsa-miR-8485	HITS-CLIP	27418678
MIRT575422	hsa-miR-8485	HITS-CLIP	27418678
MIRT575422	hsa-miR-8485	HITS-CLIP	27418678
MIRT575422	hsa-miR-8485	HITS-CLIP	27418678
MIRT575422	hsa-miR-8485	HITS-CLIP	27418678
MIRT735012	hsa-miR-373-3p	Luciferase reporter assay, qRT-PCR, In situ hybridization, Flow cytometry	33093438
MIRT575422	hsa-miR-8485	HITS-CLIP	23313552
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23313552
MIRT608056	hsa-miR-935	HITS-CLIP	23313552
MIRT575422	hsa-miR-8485	HITS-CLIP	23313552
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23313552
MIRT608056	hsa-miR-935	HITS-CLIP	23313552
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23313552
MIRT575422	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT575422	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT575422	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT575422	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT575422	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT575422	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT575422	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT575422	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT575422	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT575422	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT575422	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT575422	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT575422	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT575422	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT575422	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT575422	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT575422	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT575422	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT575422	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT608056	hsa-miR-935	HITS-CLIP	23824327
MIRT608055	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT575422	hsa-miR-8485	HITS-CLIP	23824327
MIRT608057	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT443671	hsa-miR-371b-3p	PAR-CLIP	22100165
MIRT443670	hsa-miR-371a-3p	PAR-CLIP	22100165
MIRT443669	hsa-miR-33b-3p	PAR-CLIP	22100165
MIRT443668	hsa-miR-515-3p	PAR-CLIP	22100165
MIRT443667	hsa-miR-519e-3p	PAR-CLIP	22100165
MIRT443666	hsa-miR-5189-3p	PAR-CLIP	22100165
MIRT443664	hsa-miR-4671-3p	PAR-CLIP	22100165
MIRT443665	hsa-miR-4473	PAR-CLIP	22100165
MIRT443663	hsa-miR-6844	PAR-CLIP	22100165
MIRT999025	hsa-miR-1470	CLIP-seq
MIRT999026	hsa-miR-148a	CLIP-seq
MIRT999027	hsa-miR-148b	CLIP-seq
MIRT999028	hsa-miR-152	CLIP-seq
MIRT999029	hsa-miR-1909	CLIP-seq
MIRT999030	hsa-miR-200b	CLIP-seq
MIRT999031	hsa-miR-200c	CLIP-seq
MIRT999032	hsa-miR-224	CLIP-seq
MIRT999033	hsa-miR-2682	CLIP-seq
MIRT999034	hsa-miR-3121-3p	CLIP-seq
MIRT999035	hsa-miR-34a	CLIP-seq
MIRT999036	hsa-miR-34c-5p	CLIP-seq
MIRT999037	hsa-miR-3688-3p	CLIP-seq
MIRT999038	hsa-miR-3714	CLIP-seq
MIRT999039	hsa-miR-3919	CLIP-seq
MIRT999040	hsa-miR-429	CLIP-seq
MIRT999041	hsa-miR-449a	CLIP-seq
MIRT999042	hsa-miR-449b	CLIP-seq
MIRT999043	hsa-miR-449c	CLIP-seq
MIRT999044	hsa-miR-4691-5p	CLIP-seq
MIRT999045	hsa-miR-4713-3p	CLIP-seq
MIRT999046	hsa-miR-4713-5p	CLIP-seq
MIRT999047	hsa-miR-491-3p	CLIP-seq
MIRT999048	hsa-miR-1307	CLIP-seq
MIRT999049	hsa-miR-4638-5p	CLIP-seq
MIRT999050	hsa-miR-4772-3p	CLIP-seq
MIRT999030	hsa-miR-200b	CLIP-seq
MIRT999031	hsa-miR-200c	CLIP-seq
MIRT999051	hsa-miR-30a	CLIP-seq
MIRT999052	hsa-miR-30b	CLIP-seq
MIRT999053	hsa-miR-30c	CLIP-seq
MIRT999054	hsa-miR-30d	CLIP-seq
MIRT999055	hsa-miR-30e	CLIP-seq
MIRT999056	hsa-miR-33a	CLIP-seq
MIRT999057	hsa-miR-33b	CLIP-seq
MIRT999058	hsa-miR-369-3p	CLIP-seq
MIRT999059	hsa-miR-4265	CLIP-seq
MIRT999040	hsa-miR-429	CLIP-seq
MIRT999060	hsa-miR-4296	CLIP-seq
MIRT999061	hsa-miR-4322	CLIP-seq
MIRT999062	hsa-miR-578	CLIP-seq
MIRT999063	hsa-miR-581	CLIP-seq
MIRT999064	hsa-miR-586	CLIP-seq
MIRT1996042	hsa-miR-4279	CLIP-seq
MIRT1996043	hsa-miR-1178	CLIP-seq
MIRT1996044	hsa-miR-1245	CLIP-seq
MIRT1996045	hsa-miR-136	CLIP-seq
MIRT1996046	hsa-miR-1972	CLIP-seq
MIRT1996047	hsa-miR-3194-5p	CLIP-seq
MIRT1996048	hsa-miR-4650-5p	CLIP-seq
MIRT1996049	hsa-miR-4676-5p	CLIP-seq
MIRT1996050	hsa-miR-575	CLIP-seq
MIRT999025	hsa-miR-1470	CLIP-seq
MIRT2230109	hsa-miR-3120-3p	CLIP-seq
MIRT2230110	hsa-miR-3124-3p	CLIP-seq
MIRT2230111	hsa-miR-4276	CLIP-seq
MIRT2230112	hsa-miR-4302	CLIP-seq
MIRT999046	hsa-miR-4713-5p	CLIP-seq
MIRT2230113	hsa-miR-4756-3p	CLIP-seq
MIRT2230114	hsa-miR-548t	CLIP-seq
MIRT2230115	hsa-miR-595	CLIP-seq
MIRT2230116	hsa-miR-648	CLIP-seq
MIRT2388020	hsa-miR-4780	CLIP-seq
MIRT2388021	hsa-miR-623	CLIP-seq
MIRT2449782	hsa-miR-1254	CLIP-seq
MIRT2449783	hsa-miR-1272	CLIP-seq
MIRT2449784	hsa-miR-1297	CLIP-seq
MIRT2449785	hsa-miR-1322	CLIP-seq
MIRT2449786	hsa-miR-1343	CLIP-seq
MIRT2449787	hsa-miR-1976	CLIP-seq
MIRT2449788	hsa-miR-26a	CLIP-seq
MIRT2449789	hsa-miR-26b	CLIP-seq
MIRT2449790	hsa-miR-3116	CLIP-seq
MIRT2449791	hsa-miR-3149	CLIP-seq
MIRT739478	hsa-miR-3682-3p	CLIP-seq
MIRT1996042	hsa-miR-4279	CLIP-seq
MIRT2449792	hsa-miR-4421	CLIP-seq
MIRT2449793	hsa-miR-4465	CLIP-seq
MIRT2449794	hsa-miR-4735-5p	CLIP-seq
MIRT2449795	hsa-miR-4740-3p	CLIP-seq
MIRT2449796	hsa-miR-4775	CLIP-seq
MIRT2449797	hsa-miR-4794	CLIP-seq
MIRT2449798	hsa-miR-590-3p	CLIP-seq
MIRT2449799	hsa-miR-661	CLIP-seq
MIRT2533954	hsa-miR-122	CLIP-seq
MIRT2449782	hsa-miR-1254	CLIP-seq
MIRT2449783	hsa-miR-1272	CLIP-seq
MIRT2533955	hsa-miR-139-3p	CLIP-seq
MIRT2449790	hsa-miR-3116	CLIP-seq
MIRT2533956	hsa-miR-3135b	CLIP-seq
MIRT2449791	hsa-miR-3149	CLIP-seq
MIRT2533957	hsa-miR-3652	CLIP-seq
MIRT739478	hsa-miR-3682-3p	CLIP-seq
MIRT2533958	hsa-miR-4423-5p	CLIP-seq
MIRT2533959	hsa-miR-4430	CLIP-seq
MIRT2449794	hsa-miR-4735-5p	CLIP-seq
MIRT2449796	hsa-miR-4775	CLIP-seq
MIRT2449797	hsa-miR-4794	CLIP-seq
MIRT2449798	hsa-miR-590-3p	CLIP-seq
MIRT2533960	hsa-miR-633	CLIP-seq
MIRT2449799	hsa-miR-661	CLIP-seq
MIRT2449782	hsa-miR-1254	CLIP-seq
MIRT2449790	hsa-miR-3116	CLIP-seq
MIRT2449791	hsa-miR-3149	CLIP-seq
MIRT2681048	hsa-miR-4312	CLIP-seq
MIRT2449794	hsa-miR-4735-5p	CLIP-seq
MIRT2449796	hsa-miR-4775	CLIP-seq
MIRT2449797	hsa-miR-4794	CLIP-seq
MIRT2449798	hsa-miR-590-3p	CLIP-seq
MIRT2533960	hsa-miR-633	CLIP-seq
MIRT2449799	hsa-miR-661	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
ATF1	Unknown	7499271
CREB1	Unknown	7499271
E2F1	Unknown	20516113
EGR1	Unknown	10828020
EPAS1	Activation	15192019;19616846
ESR1	Unknown	17242190
ETS1	Unknown	10554042
TP53	Activation	16432214
TP53	Unknown	1724219e

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001525	Process	Angiogenesis	IEA
GO:0002244	Process	Hematopoietic progenitor cell differentiation	IBA	21873635
GO:0002548	Process	Monocyte chemotaxis	IDA	8605350, 18079407
GO:0004714	Function	Transmembrane receptor protein tyrosine kinase activity	IBA	21873635
GO:0005021	Function	Vascular endothelial growth factor-activated receptor activity	IDA	1312256, 8605350, 9299537, 15952180
GO:0005021	Function	Vascular endothelial growth factor-activated receptor activity	IMP	11312102
GO:0005515	Function	Protein binding	IPI	1312256, 7657594, 9393862, 10543948, 12771128, 14684734, 16893970, 18273061, 20660291, 23397142
GO:0005524	Function	ATP binding	IEA
GO:0005615	Component	Extracellular space	TAS	8248162
GO:0005768	Component	Endosome	IEA
GO:0005886	Component	Plasma membrane	IDA
GO:0005886	Component	Plasma membrane	TAS
GO:0005887	Component	Integral component of plasma membrane	IBA	21873635
GO:0005887	Component	Integral component of plasma membrane	IDA	11513746
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0007169	Process	Transmembrane receptor protein tyrosine kinase signaling pathway	IBA	21873635
GO:0007275	Process	Multicellular organism development	IBA	21873635
GO:0008284	Process	Positive regulation of cell population proliferation	TAS	10748050
GO:0010863	Process	Positive regulation of phospholipase C activity	IMP	11312102
GO:0014068	Process	Positive regulation of phosphatidylinositol 3-kinase signaling	IMP	14633857
GO:0015629	Component	Actin cytoskeleton	IDA
GO:0016477	Process	Cell migration	IBA	21873635
GO:0016477	Process	Cell migration	IMP	8605350
GO:0018108	Process	Peptidyl-tyrosine phosphorylation	IDA	9299537, 11513746
GO:0019838	Function	Growth factor binding	IPI	1312256, 10471394, 11513746, 12366396, 16109918
GO:0030335	Process	Positive regulation of cell migration	IDA	8605350
GO:0033674	Process	Positive regulation of kinase activity	IBA	21873635
GO:0035924	Process	Cellular response to vascular endothelial growth factor stimulus	IDA	8605350
GO:0036323	Process	Vascular endothelial growth factor receptor-1 signaling pathway	IDA	15952180
GO:0036332	Function	Placental growth factor-activated receptor activity	IDA	12796773
GO:0038084	Process	Vascular endothelial growth factor signaling pathway	IEA
GO:0043235	Component	Receptor complex	IBA	21873635
GO:0043235	Component	Receptor complex	IDA	23382219
GO:0043406	Process	Positive regulation of MAP kinase activity	IDA	9299537
GO:0043410	Process	Positive regulation of MAPK cascade	IDA	9299537
GO:0043552	Process	Positive regulation of phosphatidylinositol 3-kinase activity	IMP	11312102
GO:0045766	Process	Positive regulation of angiogenesis	IBA	21873635
GO:0045766	Process	Positive regulation of angiogenesis	IMP	14633857, 28637396
GO:0046777	Process	Protein autophosphorylation	IDA	9299537, 11513746
GO:0048010	Process	Vascular endothelial growth factor receptor signaling pathway	IDA	1312256, 9299537
GO:0048010	Process	Vascular endothelial growth factor receptor signaling pathway	IMP	11312102
GO:0048010	Process	Vascular endothelial growth factor receptor signaling pathway	TAS
GO:0048514	Process	Blood vessel morphogenesis	ISS
GO:0048598	Process	Embryonic morphogenesis	ISS
GO:1905563	Process	Negative regulation of vascular endothelial cell proliferation	IGI	22955733
GO:1990384	Process	Hyaloid vascular plexus regression	ISS

Other IDs

• MIM: 165070
• HGNC: 3763
• e!Ensembl: ENSG00000102755

Protein

• UniProt ID: P17948
• Protein name: Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)
• Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, c
• PDB: 1FLT, 1QSV, 1QSZ, 1QTY, 1RV6, 2XAC, 3HNG, 4CKV, 4CL7, 5ABD, 5EX3, 5T89
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00047	ig	235 → 326	Immunoglobulin domain	Domain
  PF07679	I-set	337 → 426	Immunoglobulin I-set domain	Domain
  PF13927	Ig_3	560 → 640		Domain
  PF07679	I-set	661 → 748	Immunoglobulin I-set domain	Domain
  PF17988	VEGFR-2_TMD	753 → 787	VEGFR-2 Transmembrane domain	Domain
  PF07714	PK_Tyr_Ser-Thr	827 → 1154	Protein tyrosine and serine/threonine kinase	Domain

• Sequence:

  MVSYWDTGVLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHK
  WSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKET
  ESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPD
  GKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPV
  KLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDK
  MQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVK
  AFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTA
  TLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNHSEARC
  DFCSNNEESFILDADSNMGNRIESITQRMAIIEGKNKMASTLVVADSRISGIYICIASNK
  VGTVGRNISFYITDVPNGFHVNLEKMPTEGEDLKLSCTVNKFLYRDVTWILLRTVNNRTM
  HYSISKQKMAITKEHSITLNLTIMNVSLQDSGTYACRARNVYTGEEILQKKEITIRDQEA
  PYLLRNLSDHTVAISSSTTLDCHANGVPEPQITWFKNNHKIQQEPGIILGPGSSTLFIER
  VTEEDEGVYHCKATNQKGSVESSAYLTVQGTSDKSNLELITLTCTCVAATLFWLLLTLFI
  RKMKRSSSEIKTDYLSIIMDPDEVPLDEQCERLPYDASKWEFARERLKLGKSLGRGAFGK
  VVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALMTELKILTHIGHHLNVVNLLGACTK
  QGGPLMVIVEYCKYGNLSNYLKSKRDLFFLNKDAALHMEPKKEKMEPGLEQGKKPRLDSV
  TSSESFASSGFQEDKSLSDVEEEEDSDGFYKEPITMEDLISYSFQVARGMEFLSSRKCIH
  RDLAARNILLSENNVVKICDFGLARDIYKNPDYVRKGDTRLPLKWMAPESIFDKIYSTKS
  DVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLREGMRMRAPEYSTPEIYQIMLDCWHRD
  PKERPRFAELVEKLGDLLQANVQQDGKDYIPINAILTGNSGFTYSTPAFSEDFFKESISA
  PKFNSGSSDDVRYVNAFKFMSLERIKTFEELLPNATSMFDDYQGDSSTLLASPMLKRFTW
  TDSKPKASLKIDLRVTSKSKESGLSDVSRPSFCHSSCGHVSEGKRRFTYDHAELERKIAC
  CSPPPDYNSVVLYSTPPI

• Sequence length: 1338

Pathways

KEGG:

MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
HIF-1 signaling pathway
PI3K-Akt signaling pathway
Focal adhesion
Transcriptional misregulation in cancer
Rheumatoid arthritis

Reactome:

Neurophilin interactions with VEGF and VEGFR
VEGF binds to VEGFR leading to receptor dimerization

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158, rs80357524, rs80357115, rs80357945, rs80357729, rs80357609, rs80357259, rs80357981, rs80358063, rs80357389, rs80356862, rs80359876, rs80357580, rs80358053, rs80358089, rs80187739, rs397507241, rs80358069, rs80357590, rs80357284, rs80357941, rs80359261, rs80359272, rs80359276, rs276174813, rs80358474, rs80359316, rs1555282969, rs80359388, rs80359499, rs80359505, rs80359520, rs80359526, rs80359533, rs56253082, rs80358824, rs80359554, rs80359636, rs80359651, rs80359659, rs80359011, rs80359012, rs80359013, rs80359718, rs397507410, rs81002812, rs80359730, rs80359152, rs80359159, rs397507419, rs28897759, rs80359211, rs80359775, rs397514577, rs397507584, rs80358435, rs80358456, rs80359340, rs80359343, rs80359365, rs80358579, rs397507670, rs80358593, rs80359406, rs80359444, rs80359454, rs276174853, rs276174854, rs80359483, rs80359537, rs80358815, rs80358843, rs80359558, rs80359560, rs80359594, rs80358893, rs28897743, rs397507900, rs397507906, rs397507918, rs80358971, rs80358981, rs397507941, rs80359030, rs80359035, rs41293511, rs397507396, rs81002806, rs80359112, rs397508006, rs81002893, rs45580035, rs80359760, rs397508051, rs80359772, rs4987049, rs80359777, rs80357770, rs397508867, rs62625303, rs397508874, rs80357506, rs80357287, rs273898674, rs80358042, rs80358083, rs80357058, rs41286296, rs80357960, rs80356945, rs80357223, rs386134270, rs80358116, rs80357856, rs80357424, rs397509050, rs80357485, rs80357966, rs397509067, rs80357310, rs80356866, rs80357260, rs80357437, rs80358023, rs80358086, rs80357133, rs80356993, rs80357997, rs80357239, rs80357227, rs397509243, rs80356969, rs80356959, rs63750617, rs63751319, rs587779315, rs200640585, rs398122546, rs80357543, rs398122687, rs80359328, rs398122779, rs398122783, rs62517194, rs80358029, rs515726060, rs180177103, rs180177111, rs180177133, rs587776527, rs180177135, rs180177136, rs515726117, rs587779813, rs587779909, rs587780024, rs587780100, rs28909982, rs121908698, rs180177100, rs587780210, rs587780240, rs587780639, rs587781269, rs587781353, rs587781471, rs587781658, rs587781697, rs587781730, rs587781894, rs587781948, rs587782005, rs587782011, rs200928781, rs587781558, rs370228071, rs587782245, rs587782401, rs180177110, rs587782504, rs72552322, rs587782531, rs587782620, rs587782680, rs587782774, rs587782818, rs730881411, rs730881389, rs564652222, rs397507768, rs587776419, rs730881868, rs730881940, rs56383036, rs758972589, rs201089102, rs730881348, rs786202608, rs786201886, rs786203318, rs786203775, rs786203714, rs786202033, rs750621215, rs786203884, rs786203650, rs772821016, rs863224521, rs864622223, rs864622655, rs375699023, rs876659572, rs768362387, rs876659535, rs876658957, rs483353072, rs876659435, rs267608041, rs876661113, rs730881369, rs878853535, rs772228129, rs878855122, rs760551339, rs80359596, rs397509222, rs886039630, rs886039683, rs886040828, rs587781799, rs886040374, rs886040649, rs397507967, rs878854957, rs886040043, rs1057517589, rs1060502769, rs866380588, rs863224765, rs1064793243, rs747563556, rs1555074976, rs1064795885, rs753961188, rs1064794708, rs869312772, rs1064793887, rs1131690820, rs1135401928, rs1135401868, rs1135401859, rs1553370324, rs397507630, rs1555283160, rs1555283251, rs1555283262, rs1555283361, rs1555286298, rs1555288462, rs886040950, rs1555289566, rs776323117, rs80357123, rs1555579627, rs1555580697, rs80358054, rs1555593302, rs1328985852, rs763470424, rs1555139694, rs878854697, rs1555461217, rs1555461765, rs774684620, rs766416564, rs1554558613, rs1305740166, rs1555461460, rs1555461407, rs1555461586, rs1555567202, rs1555607022, rs1555069815, rs1442299125, rs1474786480, rs1555084947, rs1555457867, rs141087784, rs1482641121, rs1564830522, rs1565469955, rs1565503137, rs864622613, rs755263466, rs757679199, rs1593903166, rs1597801649, rs1603293306, rs879253880, rs80358754, rs1597062038, rs45494092, rs1603275367, rs887358871, rs1597091518, rs1966967065, rs1064793049, rs2082872908, rs2085078278, rs2072475243	23146280, 26124351
Breast carcinoma	Breast Carcinoma	rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451, rs397507859, rs80359709, rs80359742, rs80359205, rs80357627, rs80357004, rs80357571, rs80357767, rs80357653, rs80358086, rs80357608, rs28897696, rs41293465, rs146650273, rs63751017, rs63750617, rs63750726, rs63750199, rs63749848, rs398122618, rs398122653, rs397509211, rs80357791, rs121912666, rs587778541, rs121908698, rs536907995, rs587781302, rs140342925, rs587781506, rs587782652, rs587782849, rs587783057, rs10520699, rs11852999, rs139770721, rs374950566, rs786202800, rs863224451, rs377153250, rs747727055, rs876658804, rs780001540, rs760815829, rs878854926, rs775248597, rs886040658, rs886040192, rs786203523, rs886040319, rs397508006, rs587782011, rs1060502772, rs1555461727, rs1553333072, rs1114167702, rs1257401983, rs886040950, rs1060502759, rs774684620, rs142947311, rs1555580883, rs748513310, rs376170600, rs863224499, rs1593909229, rs748453607, rs1294578913, rs1574737047, rs1593909960, rs2081922847, rs2082559544, rs2053694038	26124351, 23146280
Coronary artery disease	Coronary Artery Disease	rs137852988, rs121918313, rs121918529, rs121918531, rs137852340, rs405509, rs1555800701, rs1215189537	29212778, 23202125, 28714975
Diabetes mellitus	Diabetes Mellitus, Insulin-Dependent	rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs4402960, rs1362648752, rs3745368, rs3792267, rs3842570, rs5030952, rs2975760, rs119489103, rs7903146, rs12255372, rs11196205, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237, rs80356613, rs137852740, rs137852786, rs387906407, rs151344623, rs28938469, rs28936371, rs137852672, rs80356637, rs80356642, rs80356653, rs137852673, rs137852674, rs80356634, rs80356651, rs193929360, rs137853334, rs137853335, rs137853336, rs1600731198, rs137853338, rs121964882, rs121964883, rs387906511, rs121964884, rs121964885, rs2147483647, rs387906512, rs121964887, rs121964888, rs121964889, rs121964890, rs121964891, rs28934878, rs74315383, rs121964893, rs886037620, rs886037621, rs80356663, rs121434593, rs121913150, rs587776825, rs137853236, rs2135842335, rs137853237, rs137853238, rs2135818776, rs1566092470, rs1463923467, rs137853243, rs137853244, rs2135839114, rs137853245, rs2135847417, rs121918407, rs104894005, rs104894006, rs80356655, rs104894008, rs104894009, rs104894010, rs104894011, rs80356654, rs104894016, rs193929376, rs193929374, rs193929375, rs193929373, rs80356666, rs80356669, rs80356664, rs193929366, rs1048095, rs193929355, rs193929356, rs1259467443, rs104893642, rs387906777, rs387906779, rs141804752, rs182349376, rs184917682, rs193922396, rs193922400, rs193922401, rs137852676, rs193922407, rs193922638, rs193922257, rs193922258, rs193922259, rs193922260, rs193922261, rs193922262, rs193922263, rs193922264, rs193922265, rs193922268, rs193921338, rs193922269, rs193922272, rs193922273, rs193922275, rs193922278, rs193922279, rs193922280, rs193922281, rs193922282, rs193922283, rs193922284, rs193922286, rs193922287, rs193922289, rs193922291, rs193922295, rs193922297, rs193922300, rs193922302, rs193922303, rs193922308, rs193922313, rs193922314, rs144723656, rs193922315, rs193922316, rs193922317, rs148311934, rs193922319, rs193922320, rs193922326, rs193922329, rs193922330, rs193922331, rs193922335, rs193922336, rs193922338, rs193922340, rs193922341, rs193922471, rs193922475, rs193922476, rs193922479, rs193922355, rs193922356, rs193922576, rs193922578, rs193922582, rs193922588, rs193922592, rs193922594, rs193922596, rs386134267, rs193922598, rs193922599, rs193922600, rs193922604, rs193922605, rs397514580, rs397515519, rs267601516, rs587780343, rs587780345, rs587780346, rs587780347, rs587780357, rs148954387, rs61736969, rs587783673, rs587783672, rs587783669, rs786204676, rs794727236, rs151344624, rs794727775, rs794727839, rs199946797, rs869320673, rs796065047, rs759072800, rs797045595, rs797045209, rs797045207, rs797045213, rs797045623, rs863225280, rs149703259, rs864321656, rs139964066, rs777870079, rs878853246, rs769268803, rs886039380, rs886041392, rs886041391, rs886042610, rs143064649, rs1057516192, rs746480424, rs1057516281, rs576684889, rs754728827, rs1057520291, rs1057520779, rs893256143, rs1057520504, rs1057524790, rs1057524902, rs1057524904, rs1057524905, rs764232985, rs1064793998, rs1064794268, rs769086289, rs369429452, rs1085307913, rs1131691416, rs765432081, rs1131692182, rs748749585, rs1554335441, rs762263694, rs1312678560, rs767565869, rs1375656631, rs1554335391, rs1360415315, rs1554335616, rs1554335752, rs1554909277, rs769518471, rs757171524, rs768951263, rs762703502, rs1555212248, rs1555212359, rs1555813319, rs1555816654, rs1553638903, rs1553638909, rs948820149, rs371977235, rs1553784995, rs76474829, rs200998587, rs1415041911, rs1554334894, rs1260178539, rs1554335421, rs1555211904, rs779184183, rs1554335564, rs200670692, rs1400535021, rs1554334872, rs1555212749, rs1553876668, rs1553878211, rs954727530, rs1554924035, rs372307320, rs925231098, rs1554913069, rs1554933565, rs766431403, rs746714109, rs751279984, rs770664202, rs1008906426, rs758844607, rs1554924540, rs1566092307, rs753998395, rs1565885935, rs1167124132, rs1376796469, rs556436603, rs1562715657, rs1486280029, rs1564869850, rs755259997, rs769569410, rs1172328722, rs1286294151, rs1375557127, rs1568731279, rs1562715426, rs556581174, rs1564865302, rs1565886545, rs776793516, rs1568724014, rs1392795567, rs781260712, rs1562719705, rs1382448285, rs1564977373, rs750586210, rs1598842892, rs1583592247, rs780612692, rs1593060859, rs1476637197, rs751279776, rs1593060890, rs1191912908, rs1167675604, rs1583601110, rs1593058932, rs778611627, rs753296261
Hypertension	Hypertensive disease	rs13306026, rs13333226
Kidney disease	Chronic Kidney Diseases	rs74315342, rs749740335, rs757649673, rs112417755, rs35138315
Lung adenocarcinoma	Adenocarcinoma of lung (disorder)	rs28934576, rs121913530, rs397516975, rs587776805, rs121913469, rs121913364, rs121913351, rs121913366, rs397516896, rs397516977, rs397516981, rs397517127, rs121913344, rs727504233, rs121913370, rs760043106, rs1057519788, rs1131692238, rs1131692237, rs1554350382
Marfan syndrome	Mammary Carcinoma, Human	rs137854456, rs137854457, rs267606796, rs137854458, rs137854459, rs137854460, rs137854470, rs137854471, rs267606797, rs137854461, rs137854462, rs137854463, rs869025419, rs137854464, rs137854465, rs137854466, rs137854467, rs387906547, rs387906548, rs137854469, rs137854473, rs1131692050, rs112989722, rs137854474, rs137854476, rs140593, rs1555395819, rs137854478, rs137854479, rs137854480, rs137854481, rs137854482, rs137854483, rs137854484, rs137854485, rs112289537, rs193922181, rs193922182, rs193922185, rs140603, rs193922187, rs193922188, rs193921256, rs112660651, rs193922193, rs193922194, rs193922197, rs193922198, rs193922199, rs193922203, rs193922204, rs193922205, rs193922206, rs111401431, rs193922207, rs113871094, rs111671429, rs193922216, rs193922219, rs193922220, rs193922223, rs193922224, rs193922225, rs193922226, rs193922227, rs193922228, rs193922230, rs193922235, rs147195031, rs193922236, rs193922239, rs193922240, rs193922241, rs193922246, rs397514558, rs398122934, rs397515753, rs397515754, rs397515755, rs397515756, rs397515757, rs113812345, rs397515758, rs397515759, rs397515762, rs25403, rs397515765, rs397515766, rs397515767, rs397515768, rs397515769, rs397515770, rs397515771, rs25404, rs397515773, rs397515774, rs397515775, rs397515776, rs397515778, rs397515779, rs397515781, rs112202622, rs397515782, rs397515784, rs397515785, rs397515786, rs397515788, rs397515789, rs397515790, rs397515791, rs397515792, rs397515793, rs397515794, rs397515797, rs397515798, rs397515799, rs397515801, rs397515802, rs397515803, rs397515804, rs397515805, rs397515808, rs397515810, rs397515811, rs397515812, rs111231312, rs267606798, rs397515814, rs113905529, rs397515816, rs397515817, rs397515818, rs397515819, rs397515820, rs363853, rs113249837, rs397515821, rs111929350, rs397515823, rs397515824, rs113086760, rs397515825, rs397515826, rs397515827, rs363807, rs397515828, rs397515829, rs397515830, rs397515831, rs397515833, rs111687884, rs113080385, rs397515834, rs397515836, rs113001196, rs397515840, rs397515845, rs397515846, rs397515847, rs397515848, rs397515851, rs397515852, rs397515853, rs397515854, rs111856492, rs397515859, rs397515861, rs397515863, rs397515864, rs397515865, rs397515866, rs397515867, rs137854855, rs199474693, rs587782944, rs587782947, rs587782948, rs672601352, rs876658120, rs727504651, rs727503054, rs727504315, rs727504411, rs727503057, rs727504454, rs200309328, rs363811, rs727504410, rs363821, rs727504347, rs727505006, rs727505110, rs730880356, rs727505269, rs727503058, rs727504421, rs730880107, rs730880104, rs730880103, rs730880102, rs730880101, rs730880106, rs730880100, rs730880105, rs730880099, rs112645512, rs730880108, rs730880098, rs730880097, rs794728321, rs794728283, rs794728280, rs794728336, rs794728272, rs794728160, rs794728271, rs794728270, rs794728319, rs794728262, rs794728251, rs76702162, rs794728335, rs794728334, rs794728246, rs763091520, rs794728333, rs794728237, rs761857514, rs794728234, rs140630, rs794728231, rs794728228, rs794728225, rs794728308, rs794728216, rs794728221, rs763449629, rs201058219, rs794728210, rs794728208, rs794728206, rs794728199, rs794728195, rs794728194, rs794728193, rs794728190, rs1555399381, rs794728176, rs1555399968, rs113422242, rs794728326, rs794728166, rs794728325, rs794728165, rs794728162, rs794728213, rs869025417, rs112642323, rs869025416, rs869025415, rs869025424, rs869025423, rs869025414, rs869025422, rs869025413, rs869025412, rs869025411, rs869025418, rs869025426, rs869025406, rs869025421, rs869025425, rs869025404, rs869025420, rs869025403, rs398122833, rs876657645, rs878853686, rs878853676, rs886038919, rs886038795, rs187553035, rs886038869, rs886038949, rs886038967, rs886038976, rs886038848, rs886038940, rs886038877, rs886039038, rs886038817, rs886038963, rs886039036, rs886038797, rs886039550, rs886041482, rs1057517855, rs1057518912, rs1057518973, rs1057519502, rs1057521100, rs1057521102, rs1057518881, rs1057520617, rs1057521101, rs1555394445, rs369058466, rs1060501069, rs1060501031, rs778966916, rs1060501043, rs1555397663, rs1060501017, rs1060501094, rs1060501065, rs1555393848, rs1555394151, rs1060501051, rs1060501013, rs1060501054, rs1060501048, rs1060501089, rs1060501039, rs1555398160, rs1060501022, rs1060501024, rs1060501086, rs1060501058, rs1060501036, rs1060501100, rs1060501042, rs1060501059, rs1555397743, rs1060501021, rs1060501027, rs1060501096, rs1060501038, rs1060501050, rs1064794130, rs112118237, rs1064793980, rs1064793118, rs1064793636, rs1064794282, rs1064793559, rs1085307921, rs1085308004, rs1085307468, rs112907302, rs1131691479, rs1131691373, rs1131691467, rs1131691938, rs1131691311, rs1131691806, rs1131691317, rs1555393827, rs363804, rs1555397738, rs1555399144, rs1555400274, rs1555394195, rs1555398836, rs113543334, rs1555399825, rs1555394626, rs1555395256, rs1555395257, rs1555396427, rs1555397548, rs1555398173, rs1555404803, rs1232880706, rs1555393825, rs1555394567, rs1555396998, rs1555394928, rs1555397203, rs112375043, rs1555397720, rs140599, rs1555399150, rs1555400373, rs1555405041, rs1555395229, rs1555397671, rs775417975, rs1555398774, rs1555399368, rs1555394904, rs1555395987, rs1555397424, rs1555398377, rs1555398835, rs1555401011, rs1555405043, rs1555394580, rs1555397404, rs1555398511, rs1555395826, rs1555399372, rs1555399821, rs1555399836, rs1555400063, rs363810, rs1555397655, rs1555395756, rs1555395742, rs1555393844, rs112550005, rs1555395002, rs1555395658, rs765387131, rs1555396429, rs1555396835, rs1555397014, rs1555397016, rs778710767, rs1555397557, rs1555397704, rs140648, rs1555398406, rs1555398681, rs1555399257, rs1555399361, rs1555399764, rs1555405056, rs1555393510, rs1555395980, rs1555396789, rs1555399094, rs1555399378, rs1555399816, rs1555395645, rs371097218, rs1555398278, rs1555394238, rs1555396418, rs1206813753, rs1555399271, rs1555405044, rs113544411, rs1555395663, rs1555397216, rs1555398989, rs1555399149, rs1555401670, rs1555395001, rs1445085747, rs1555393538, rs1555393565, rs1404133653, rs1555394450, rs1555394581, rs1555394633, rs1555394900, rs1555395189, rs1555395261, rs1052480459, rs1555395480, rs1555395670, rs363806, rs1555395820, rs1555396419, rs1555396765, rs1296209846, rs794728233, rs1555396853, rs1555396863, rs1555397197, rs1555397204, rs1555397212, rs1555397713, rs1555397736, rs1555398139, rs1555398144, rs1555398409, rs1555398510, rs1555398520, rs1555398524, rs1555398667, rs1555399089, rs1555399482, rs1555399763, rs1555401002, rs794728323, rs1555393508, rs1555393514, rs1555393525, rs1555393532, rs1555393653, rs1555393657, rs1555393824, rs1555393831, rs112196241, rs1555393847, rs1555393862, rs1555393863, rs1555393866, rs113935744, rs1555393882, rs1555393886, rs1555393889, rs1555394138, rs1555394144, rs1555394146, rs1555394148, rs1555394149, rs1555394152, rs1555394153, rs1555394189, rs1555394197, rs1555394206, rs1555394212, rs1555394218, rs1555394220, rs1555394235, rs1555394245, rs1555394246, rs1057520728, rs1555394390, rs1555394391, rs537570299, rs1555394397, rs1555394398, rs1555394399, rs1555394402, rs1555394407, rs1555394412, rs1555394435, rs1555394436, rs1555394441, rs1555394556, rs1555394557, rs1555394559, rs1555394561, rs1555394570, rs397515844, rs1555394571, rs1555394574, rs1555394579, rs1555394582, rs534811966, rs111588631, rs1555394628, rs1555394629, rs1555394630, rs1555394631, rs1555394641, rs1555394644, rs1555394647, rs1555394756, rs886051245, rs1555394775, rs1555394776, rs1555394777, rs1555394779, rs1555394780, rs1555394783, rs1555394901, rs1555394906, rs1555394925, rs794728253, rs886039158, rs1555395013, rs1555395187, rs1555395188, rs1555395203, rs1555395205, rs363815, rs1246984265, rs794728245, rs1555395263, rs1555395267, rs1555395456, rs1555395475, rs1555395482, rs1555395638, rs1555395641, rs1555395648, rs1555395653, rs1555395659, rs111239111, rs1555395745, rs1555395747, rs1555395753, rs1555395757, rs1555395766, rs1555395767, rs1555395843, rs1555395846, rs1555395849, rs1555395978, rs1555395981, rs1555395984, rs1555395989, rs1555395990, rs1260109901, rs1555396186, rs1555396188, rs1555396198, rs1555396199, rs1555396201, rs1555396202, rs1555396205, rs1555396213, rs1555396424, rs1555396426, rs1555396428, rs1555396435, rs1555396630, rs1555396635, rs1555396636, rs1555396639, rs1555396757, rs1555396769, rs1555396838, rs1555396844, rs140627, rs1555396858, rs1555396990, rs1555396991, rs1555396993, rs769588424, rs1555397022, rs1555397024, rs1555397160, rs1555397174, rs1555397176, rs1555397193, rs1555397209, rs1555397210, rs1555397214, rs1060501076, rs113082854, rs113693945, rs111978932, rs1555397403, rs1555397419, rs1555397420, rs1555397421, rs1555397536, rs1555397537, rs1555397540, rs1555397542, rs1555397543, rs1555397545, rs1555397546, rs1555397670, rs1555397692, rs1555397718, rs1555397723, rs1555397744, rs113393517, rs1555398148, rs1555398152, rs1555398174, rs1555398176, rs1555398179, rs1555398282, rs1555398287, rs1555398380, rs1555398394, rs1555398397, rs1555398401, rs1555398404, rs1555398407, rs1555398413, rs1555398501, rs1555398508, rs1555398512, rs1555398513, rs1555398515, rs1555398521, rs794728205, rs1555398527, rs1555398551, rs1060501075, rs1555398566, rs1555398572, rs1555398580, rs1555398582, rs140597, rs1555398622, rs1555398624, rs1555398625, rs112547596, rs1555398627, rs1555398633, rs1555398637, rs1555398642, rs778867355, rs1555398648, rs1555398659, rs1293095681, rs1060501040, rs987202268, rs1555398672, rs1555398673, rs1555398677, rs1555398793, rs1555398803, rs1555398811, rs1555398826, rs1555398833, rs1555398974, rs1555398981, rs778900586, rs1555398988, rs1555398994, rs1555398995, rs1555398996, rs1555399093, rs869025405, rs1555399101, rs1555399146, rs1555399160, rs1555399162, rs1555399164, rs1555399165, rs1555399193, rs1555399195, rs1555399202, rs1555399204, rs1555399206, rs201778577, rs1555399210, rs1555399214, rs1555399270, rs1555399273, rs1555399281, rs1555399371, rs1555399385, rs1555399477, rs1555399484, rs1555399761, rs1555399775, rs1555399802, rs1555399804, rs1555399837, rs1555399840, rs1555399940, rs1555399944, rs1555399949, rs1555399953, rs1555399954, rs1555399955, rs1555399959, rs1555399962, rs1555399963, rs1060501041, rs1555399974, rs1555399976, rs1555399977, rs1555400049, rs794728172, rs1555400062, rs1555400064, rs1555400066, rs1555400267, rs1555400268, rs1555400278, rs794728168, rs1555400279, rs1156747241, rs1555400288, rs1555400371, rs1555400372, rs1555400379, rs1555400385, rs587782943, rs1555400387, rs1555400406, rs1439533354, rs746201757, rs1555400595, rs1555400603, rs1555400604, rs1555400606, rs1555400609, rs752010116, rs1555400612, rs1555400616, rs1555401004, rs1555401005, rs146348130, rs1555401667, rs1555401671, rs1555401676, rs1555401679, rs1555401687, rs1555401689, rs1555401695, rs1555401697, rs1555401701, rs1555404799, rs1555404800, rs200295020, rs1555404810, rs1555404820, rs1555405031, rs1555405039, rs1555405045, rs1555405530, rs794728292, rs1555405533, rs1555405536, rs1555405537, rs111764111, rs1555405658, rs1555405664, rs774371494, rs1555405673, rs1555407399, rs1555407414, rs1555407423, rs1555407429, rs886041536, rs1555404806, rs1566911709, rs1566913974, rs1566894226, rs1566895223, rs1566897376, rs1566902526, rs1566915277, rs1566897374, rs1566897420, rs1566891655, rs1346043320, rs1566922396, rs1566891706, rs1566894783, rs1566913670, rs1555394196, rs1566891454, rs1566891406, rs1566891404, rs1566895262, rs1566891645, rs1566895225, rs1566896114, rs1566898399, rs1566904011, rs1566906537, rs1566908956, rs1566909766, rs1566919599, rs1566937712, rs1566915335, rs1566891675, rs1566904526, rs1566906506, rs1566900540, rs1566894230, rs1555395206, rs1566891797, rs1597512576, rs1597523873, rs1597581001, rs1597516325, rs1057524757, rs1597506641, rs1597520781, rs1597593695, rs1597529829, rs1597520625, rs1597579923, rs1597531796, rs1008275504, rs1597567249, rs1597569265, rs1597652471, rs1597516347, rs1597577114, rs1597633163, rs1597519658, rs1597593852, rs1597516501, rs1566913982, rs1555393859, rs1597513708, rs368978109, rs1480832655, rs1597520683, rs1597522390, rs1597522553, rs1597529748, rs1597533707, rs1597537815, rs1597545309, rs1597545836, rs1597563234, rs1597563280, rs1597564359, rs772108557, rs1597568968, rs1597574236, rs1597574308, rs1597577975, rs193922179, rs1597581005, rs1597593736, rs1597623670, rs1597625734, rs1597631662, rs113604459, rs1597633183, rs1597633219, rs1597518951, rs1555394781, rs1597525871, rs1597526073, rs1597569159, rs1597569536, rs1597563934, rs1597545199, rs1364210063, rs1597552583, rs1597520619, rs1597540854, rs1597591602, rs1597569551, rs1597548716, rs1597553721, rs112728248, rs1597537858, rs1597517935, rs1597540907, rs1597552388, rs1597591643, rs1597529841, rs1597506547, rs1597509836, rs1597529686, rs1566897404, rs1597533713, rs1597543486, rs1597545257, rs1597545345, rs1597548672, rs1597562812, rs1597563287, rs1597571391, rs1555400052, rs1597583989, rs363852, rs1597547226, rs363808, rs974604498, rs2043595650, rs2043526284, rs2042997306, rs1555397195, rs886039054, rs1555397213, rs2042873946	26124351, 23146280
Melanoma	melanoma	rs121913315, rs121913323, rs137853080, rs137853081, rs121909232, rs121913388, rs104894094, rs1563902635, rs104894095, rs104894097, rs104894098, rs104894099, rs104894109, rs137854599, rs11547328, rs104894340, rs398123152, rs587780668, rs587782083, rs587782206, rs587782792, rs180177042, rs121913381, rs730881675, rs730881674, rs730881677, rs730881673, rs1800586, rs768966657, rs587778189, rs786204195, rs121913321, rs45476696, rs864622636, rs864622263, rs869025340, rs876660436, rs876658534, rs876658556, rs878853647, rs878853644, rs878853650, rs886041162, rs121913389, rs1057519852, rs121913384, rs121913387, rs1060501266, rs1060501263, rs1060501262, rs749714198, rs1060501265, rs559848002, rs1064794292, rs1131691187, rs1131691186, rs199907548, rs1554654052, rs1554656411, rs1554656624, rs1554653915, rs1554653956, rs1554656253, rs1554654224, rs754806883, rs1057520039, rs1563889584, rs1563889685, rs1287464120, rs1563888944, rs1563892715, rs1563889847, rs141798398, rs1587332338, rs1587340291, rs11552823, rs561034503, rs138677674, rs1819962958, rs1820531050	19718025
Melnick-needles syndrome	Melnick-Needles Syndrome	rs28935472, rs28935473	17954590
Multiple epiphyseal dysplasia	Multiple Epiphyseal Dysplasia	rs786200881, rs104893915, rs104893919, rs104893916, rs386833492, rs104893924, rs104893645, rs104893637, rs28939677, rs104893641, rs137852654, rs193922900, rs137852655, rs869320730, rs28936368, rs752248403, rs312262900, rs386833495, rs386833497, rs386833499, rs200963884, rs149551600, rs397515546, rs786204675, rs886039282, rs1057517523, rs1057517496, rs1057517462, rs1057517504, rs763198695, rs1057517483, rs1057517461, rs1057517524, rs1057517514, rs1057517526, rs1057517495, rs1057517532, rs1057517471, rs1057517502, rs1057517511, rs1057517482, rs1057517530, rs1057517474, rs762137330, rs1057517513, rs1014317450, rs1554095084, rs769859976, rs1554095145, rs1554095356, rs1554095374, rs1554095137, rs1554095156, rs745774620, rs1554095364, rs1481910744, rs1554095097, rs1554095125, rs1554095154, rs769657401, rs1554095381, rs1554095167, rs1554095266, rs1225601391, rs1554095296, rs1554095395, rs1235928535, rs1568554988, rs1561822760, rs1601054002, rs1601057167, rs1601054715, rs2055184939	17954590
Osteochondrodysplasia	Osteochondrodysplasias	rs386833498, rs104893919, rs104893916, rs386833492, rs121908078, rs386833497, rs386833507, rs200963884, rs121908077, rs786204675, rs763198695, rs1554095433, rs766836061	17954590
Papillary renal carcinoma	Papillary Renal Cell Carcinoma	rs5030823, rs2137087134, rs121913668, rs121913669, rs121913670, rs121913671, rs121913673, rs121913243, rs786202724	16596207
Renal carcinoma	Renal Cell Carcinoma, Conventional (Clear Cell) Renal Cell Carcinoma, Sarcomatoid Renal Cell Carcinoma, Collecting Duct Carcinoma of the Kidney	rs121913668, rs121913670, rs121913243, rs786202724	16596207
Schwartz-jampel syndrome	Schwartz-Jampel Syndrome	rs886039909, rs927473035, rs1572304438, rs1572356343	17954590
Spondyloenchondrodysplasia	Spondyloepiphyseal Dysplasia Tarda, X-Linked	rs121908616, rs267606734, rs121908617, rs121908618, rs1589509884, rs121908619, rs121908620, rs145538723, rs267606733, rs267606732, rs587776752, rs121912870, rs121912871, rs121912875, rs121912880, rs121912881, rs786200938, rs397514718, rs786200939, rs397514719, rs397514720, rs397514723, rs397514724, rs786200943, rs747171013, rs886039542, rs1553658926, rs1553659131, rs1181638652, rs1553667072, rs1553669703, rs769540174, rs1554022725, rs1555168505, rs1316347883, rs771866012, rs1553151294, rs1416783446, rs1565460853, rs771258750, rs1226321681, rs1294100541, rs1564532120, rs113683179, rs1597675888, rs1597675890, rs1202786652, rs377527583, rs1603225182, rs2085516391, rs934768094, rs2058757423, rs1589509307, rs771336246	17954590
Spondyloepiphyseal dysplasia	Spondyloepiphyseal Dysplasia	rs72555367, rs121908950, rs121908951, rs121908952, rs104893637, rs104893639, rs387906534, rs121913568, rs606231241, rs606231242, rs786200933, rs606231243, rs786200934, rs397515546, rs797045099, rs869312907, rs886041895, rs760093841, rs374379931, rs1471554906, rs1567185220, rs1567186585, rs1592198747, rs1239366051, rs1592197682	17954590

Unknown
Disease name	Disease term	dbSNP ID	References
Mammary neoplasms	Mammary Neoplasms, Human, Mammary Neoplasms		23146280, 26124351
Chondrodystrophic myotonia	Schwartz-Jampel Syndrome, Type 1		17954590
Chromophobe carcinoma	Chromophobe Renal Cell Carcinoma	rs137853247	16596207
Coronary heart disease	Coronary heart disease	rs9289231, rs281864746	23364394
Dyschondroplasias	Dyschondroplasias		17954590
Dyssomnia	Dyssomnias
Hemangiosarcoma	Hemangiosarcoma	rs199469669	17569031
Liver cirrhosis	Liver Cirrhosis		11981751
Liver fibrosis	Fibrosis, Liver		11981751
Polycystic ovary syndrome	Polycystic Ovary Syndrome
Preeclampsia	Preeclampsia	rs1553354646, rs1555628672
Skin cancer	Malignant neoplasm of skin		19718025
Skin neoplasms	Skin Neoplasms		19718025
Sleep disorders	Sleep Disorders
Bladder carcinoma	Transitional cell carcinoma of bladder
Uremia	Uremia		19092814
Van buchem disease	Van Buchem disease		17954590