Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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23208 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Synaptotagmin 11 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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SYT11 |
SynonymsGene synonyms aliases
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SYT12, sytXI |
ChromosomeChromosome number
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1 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1q22 |
SummarySummary of gene provided in NCBI Entrez Gene.
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This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is a |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
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UniProt ID |
Q9BT88 |
Protein name |
Synaptotagmin-11 (Synaptotagmin XI) (SytXI) |
Protein function |
Synaptotagmin family member involved in vesicular and membrane trafficking which does not bind Ca(2+). Inhibits clathrin-mediated and bulk endocytosis, functions to ensure precision in vesicle retrieval. Plays an important role in dopamine trans |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00168 |
C2 |
172 → 279 |
C2 domain |
Domain |
PF00168 |
C2 |
306 → 414 |
C2 domain |
Domain |
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Sequence |
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Sequence length |
431 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Schizophrenia |
Schizophrenia |
rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 |
17192956 |
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