Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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23197 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Fas associated factor family member 2 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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FAF2 |
SynonymsGene synonyms aliases
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ETEA, UBXD8, UBXN3B |
ChromosomeChromosome number
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5 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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5q35.2 |
SummarySummary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is highly expressed in peripheral blood of patients with atopic dermatitis (AD), compared to normal individuals. It may play a role in regulating the resistance to apoptosis that is observed in T cells and eosinophils of A |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
|
UniProt ID |
Q96CS3 |
Protein name |
FAS-associated factor 2 (UBX domain-containing protein 3B) (UBX domain-containing protein 8) |
Protein function |
Plays an important role in endoplasmic reticulum-associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:18711132, PubMed:24215460). By controlling the steady-state expressi |
PDB |
2DAM
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Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF14555 |
UBA_4 |
14 → 57 |
|
Domain |
PF00789 |
UBX |
357 → 441 |
UBX domain |
Domain |
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Sequence |
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Sequence length |
445 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Prostate cancer |
Malignant neoplasm of prostate |
rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 |
17199135 |
|
Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Prostatic neoplasms |
Prostatic Neoplasms |
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17199135 |
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