Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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23034 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Sterile alpha motif domain containing 4A |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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SAMD4A |
SynonymsGene synonyms aliases
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SAMD4, SMAUG, SMAUG1, SMG, SMGA |
ChromosomeChromosome number
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14 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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14q22.2 |
SummarySummary of gene provided in NCBI Entrez Gene.
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Sterile alpha motifs (SAMs) in proteins such as SAMD4A are part of an RNA-binding domain that functions as a posttranscriptional regulator by binding to an RNA sequence motif known as the Smaug recognition element, which was named after the Drosophila Sma |
miRNAmiRNA information provided by mirtarbase database.
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Transcription factors
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Transcription factor |
Regulation |
Reference |
SRF |
Activation |
16814806 |
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
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UniProt ID |
Q9UPU9 |
Protein name |
Protein Smaug homolog 1 (Smaug 1) (hSmaug1) (Sterile alpha motif domain-containing protein 4A) (SAM domain-containing protein 4A) |
Protein function |
Acts as a translational repressor of SRE-containing messengers. |
PDB |
8OIK
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Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00536 |
SAM_1 |
321 → 381 |
SAM domain (Sterile alpha motif) |
Domain |
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Sequence |
MMFRDQVGVLAGWFKGWNECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLER EANSPGIINQWQQESKDKVISLLLTHLPLLKPGNLDAKVEYMKLLPKILAHSIEHNQHIE ESRQLLSYALIHPATSLEDRSALAMWLNHLEDRTSTSFGGQNRGRSDSVDYGQTHYYHQR QNSDDKLNGWQNSRDSGICINASNWQDKSMGCENGHVPLYSSSSVPTTINTIGTSTSTIL SGQAHHSPLKRSVSLTPPMNVPNQPLGHGWMSHEDLRARGPQCLPSDHAPLSPQSSVASS GSGGSEHLEDQTTARNTFQEEGSGMKDVPAWLKSLRLHKYAALFSQMTYEEMMALTECQL EAQNVTKGARHKIVISIQKLKERQNLLKSLERDIIEGGSLRIPLQELHQMILTPIKAYSS PSTTPEARRREPQAPRQPSLMGPESQSPDCKDGAAATGATATPSAGASGGLQPHQLSSCD GELAVAPLPEGDLPGQFTRVMGKVCTQLLVSRPDEENISSYLQLIDKCLIHEAFTETQKK RLLSWKQQVQKLFRSFPRKTLLDISGYRQQRNRGFGQSNSLPTAGSVGGGMGRRNPRQYQ IPSRNVPSARLGLLGTSGFVSSNQRNTTATPTIMKQGRQNLWFANPGGSNSMPSRTHSSV QRTRSLPVHTSPQNMLMFQQPEFQLPVTEPDINNRLESLCLSMTEHALGDGVDRTSTI
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Sequence length |
718 |
Interactions |
View interactions |
Associated diseases
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Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Lip and oral cavity carcinoma |
Lip and Oral Cavity Carcinoma |
rs121913388, rs121912651, rs11540652, rs28934573, rs28934578, rs28933406, rs104894229, rs104894230, rs121913273, rs104894228, rs587778720, rs55832599, rs121913344, rs587782705, rs104894226, rs730882001, rs876660754, rs876660726, rs2124437, rs1335022, rs4512367, rs121913449, rs121913454, rs121913389, rs1057519927, rs243865, rs10090787, rs9849237, rs1957358, rs2306058, rs11130760, rs985033810, rs868137297 |
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Schizophrenia |
Schizophrenia |
rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 |
27846195 |
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