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ARL5B (ARF like GTPase 5B)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
221079
Gene nameGene Name - the full gene name approved by the HGNC.
ARF like GTPase 5B
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
ARL5B
SynonymsGene synonyms aliases
ARL8
ChromosomeChromosome number
10
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
10p12.31
SummarySummary of gene provided in NCBI Entrez Gene.
ARL5B (ARL8) belongs to a family of proteins that are structurally similar to ADP-ribosylation factors (ARFs; see MIM 103180). ARLs and ARFs are part of the RAS superfamily of regulatory GTPases.[supplied by OMIM, Nov 2010]
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT001567 hsa-miR-155-5p pSILAC 18668040
MIRT017382 hsa-miR-335-5p Microarray 18185580
MIRT001567 hsa-miR-155-5p Proteomics;Other 18668040
MIRT044984 hsa-miR-186-5p CLASH 23622248
MIRT669480 hsa-miR-6828-3p HITS-CLIP 23824327
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0005525 Function GTP binding IBA 21873635
GO:0005737 Component Cytoplasm IBA 21873635
GO:0005802 Component Trans-Golgi network IBA 21873635
GO:0006886 Process Intracellular protein transport IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q96KC2
Protein name ADP-ribosylation factor-like protein 5B (ADP-ribosylation factor-like protein 8)
Protein function Binds and exchanges GTP and GDP.
PDB 1YZG
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00025 Arf
1 176
ADP-ribosylation factor family
Domain
Sequence
Sequence length 179
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Melanoma melanoma rs121913315, rs121913323, rs137853080, rs137853081, rs121909232, rs121913388, rs104894094, rs1563902635, rs104894095, rs104894097, rs104894098, rs104894099, rs104894109, rs137854599, rs11547328, rs104894340, rs398123152, rs587780668, rs587782083, rs587782206, rs587782792, rs180177042, rs121913381, rs730881675, rs730881674, rs730881677, rs730881673, rs1800586, rs768966657, rs587778189, rs786204195, rs121913321, rs45476696, rs864622636, rs864622263, rs869025340, rs876660436, rs876658534, rs876658556, rs878853647, rs878853644, rs878853650, rs886041162, rs121913389, rs1057519852, rs121913384, rs121913387, rs1060501266, rs1060501263, rs1060501262, rs749714198, rs1060501265, rs559848002, rs1064794292, rs1131691187, rs1131691186, rs199907548, rs1554654052, rs1554656411, rs1554656624, rs1554653915, rs1554653956, rs1554656253, rs1554654224, rs754806883, rs1057520039, rs1563889584, rs1563889685, rs1287464120, rs1563888944, rs1563892715, rs1563889847, rs141798398, rs1587332338, rs1587340291, rs11552823, rs561034503, rs138677674, rs1819962958, rs1820531050 22535842
Unknown
Disease name Disease term dbSNP ID References
Mental depression Major Depressive Disorder rs587778876, rs587778877 31164008

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