Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
220134 |
Gene nameGene Name - the full gene name approved by the HGNC.
|
Spindle and kinetochore associated complex subunit 1 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
SKA1 |
SynonymsGene synonyms aliases
|
C18orf24 |
ChromosomeChromosome number
|
18 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
18q21.1 |
miRNAmiRNA information provided by mirtarbase database.
|
|
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
|
GO ID |
Ontology |
Definition |
Evidence |
Reference |
GO:0000278 |
Process |
Mitotic cell cycle |
IBA |
21873635 |
GO:0000278 |
Process |
Mitotic cell cycle |
IMP |
19289083 |
GO:0000940 |
Component |
Condensed chromosome outer kinetochore |
IBA |
21873635 |
GO:0000940 |
Component |
Condensed chromosome outer kinetochore |
IDA |
17093495, 19289083 |
GO:0005515 |
Function |
Protein binding |
IPI |
16189514, 17093495, 19289083, 19360002, 25416956, 26496610, 28514442, 31515488, 32296183 |
GO:0005829 |
Component |
Cytosol |
TAS |
|
GO:0005876 |
Component |
Spindle microtubule |
IBA |
21873635 |
GO:0005876 |
Component |
Spindle microtubule |
IDA |
17093495, 19289083 |
GO:0007059 |
Process |
Chromosome segregation |
IBA |
21873635 |
GO:0007059 |
Process |
Chromosome segregation |
IMP |
19289083 |
GO:0008017 |
Function |
Microtubule binding |
IBA |
21873635 |
GO:0008017 |
Function |
Microtubule binding |
IDA |
19289083 |
GO:0015630 |
Component |
Microtubule cytoskeleton |
IDA |
|
GO:0031110 |
Process |
Regulation of microtubule polymerization or depolymerization |
IBA |
21873635 |
GO:0031110 |
Process |
Regulation of microtubule polymerization or depolymerization |
IDA |
19289083 |
GO:0051301 |
Process |
Cell division |
IBA |
21873635 |
GO:0051301 |
Process |
Cell division |
IMP |
17093495 |
GO:0072686 |
Component |
Mitotic spindle |
IBA |
21873635 |
|
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|
Protein
|
UniProt ID |
Q96BD8 |
Protein name |
SKA complex subunit 1 (Spindle and kinetochore-associated protein 1) |
Protein function |
Component of the SKA complex, a microtubule plus end-binding complex of the outer kinetochore that stabilizes spindle microtubule-kinetochore attachments, promotes alignment of chromosomes at the mitotic spindle equator (chromosome congression) |
PDB |
4AJ5
,
4C9Y
,
4CA0
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF07160 |
SKA1 |
16 → 248 |
Spindle and kinetochore-associated protein 1 |
Family |
|
Sequence |
|
Sequence length |
255 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
|
|
Associated diseases
|
Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Liver carcinoma |
Liver carcinoma |
|
28284560 |
|