Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
2171 |
Gene nameGene Name - the full gene name approved by the HGNC.
|
Fatty acid binding protein 5 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
FABP5 |
SynonymsGene synonyms aliases
|
E-FABP, EFABP, KFABP, PA-FABP, PAFABP |
ChromosomeChromosome number
|
8 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
8q21.13 |
SummarySummary of gene provided in NCBI Entrez Gene.
|
This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fa |
Transcription factors
|
Transcription factor |
Regulation |
Reference |
KLF2 |
Repression |
20424164 |
|
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
|
|
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|
Protein
|
UniProt ID |
Q01469 |
Protein name |
Fatty acid-binding protein 5 (Epidermal-type fatty acid-binding protein) (E-FABP) (Fatty acid-binding protein, epidermal) (Psoriasis-associated fatty acid-binding protein homolog) (PA-FABP) |
Protein function |
Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specific fatty |
PDB |
1B56
,
1JJJ
,
4AZM
,
4AZR
,
4LKP
,
4LKT
,
5HZ5
,
5UR9
,
7FWI
,
7FXD
,
7FY0
,
7FYD
,
7G01
,
7G04
,
7G0B
,
7G0E
,
7G1Q
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00061 |
Lipocalin |
8 → 134 |
Lipocalin / cytosolic fatty-acid binding protein family |
Domain |
|
Sequence |
|
Sequence length |
135 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
|
|
Associated diseases
|
Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Schizophrenia |
Schizophrenia |
rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 |
25027319, 19554614 |
|
Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Liver carcinoma |
Liver carcinoma |
|
21472284 |
Myocardial ischemia |
Myocardial Ischemia |
|
16214533 |
|