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ETV5 (ETS variant transcription factor 5)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
2119
Gene nameGene Name - the full gene name approved by the HGNC.
ETS variant transcription factor 5
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
ETV5
SynonymsGene synonyms aliases
ERM
ChromosomeChromosome number
3
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3q27.2
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT017311 hsa-miR-335-5p Microarray 18185580
MIRT530651 hsa-miR-4453 PAR-CLIP 22012620
MIRT530650 hsa-miR-4538 PAR-CLIP 22012620
MIRT530649 hsa-miR-1539 PAR-CLIP 22012620
MIRT530648 hsa-miR-5689 PAR-CLIP 22012620
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IDA 17126306
GO:0000785 Component Chromatin ISA
GO:0000976 Function Transcription regulatory region sequence-specific DNA binding IDA 19443906
GO:0000977 Function RNA polymerase II transcription regulatory region sequence-specific DNA binding IMP 15857832
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID P41161
Protein name ETS translocation variant 5 (Ets-related protein ERM)
Protein function Binds to DNA sequences containing the consensus nucleotide core sequence 5'-GGAA.-3'.
PDB 4UNO , 5ILV
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04621 ETS_PEA3_N
1 366
PEA3 subfamily ETS-domain transcription factor N terminal domain
Family
PF00178 Ets
369 448
Ets-domain
Domain
Sequence
Sequence length 510
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
KEGG
 
  Transcriptional misregulation in cancer
Prostate cancer
 
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Obesity Obesity rs34911341, rs74315349, rs1474810899, rs2282440, rs2491132, rs121918111, rs796065034, rs753856820, rs796065035, rs121918112, rs104894023, rs137852821, rs1580764441, rs137852822, rs137852823, rs137852824, rs13447324, rs121913562, rs121913564, rs74315393, rs121913556, rs2989924, rs193922650, rs193922685, rs193922687, rs751160202, rs1421085, rs747681609, rs1553400259, rs13447339, rs370479598, rs1554394014, rs1553174844, rs756232889, rs369841551, rs1557670950, rs1571321748, rs148538980, rs1572820988, rs1591461970, rs1419374563, rs745921568, rs144159890, rs1570714352, rs779783209, rs1573250294, rs1573254045, rs1580744791, rs1580746829, rs6548238, rs7138803, rs7754840 23563607
Prostate cancer Malignant neoplasm of prostate rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 27783944
Unknown
Disease name Disease term dbSNP ID References
Hyperuricemia Hyperuricemia 29124443
Prostatic neoplasms Prostatic Neoplasms 27783944

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