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STX2 (syntaxin 2)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
2054
Gene nameGene Name - the full gene name approved by the HGNC.
Syntaxin 2
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
STX2
SynonymsGene synonyms aliases
EPIM, EPM, STX2A, STX2B, STX2C
ChromosomeChromosome number
12
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12q24.33
SummarySummary of gene provided in NCBI Entrez Gene.
The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT002690 hsa-miR-124-3p Microarray 15685193
MIRT052827 hsa-miR-3200-3p CLASH 23622248
MIRT680922 hsa-miR-1247-3p HITS-CLIP 23706177
MIRT680921 hsa-miR-3160-3p HITS-CLIP 23706177
MIRT680920 hsa-miR-558 HITS-CLIP 23706177
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000149 Function SNARE binding IBA 21873635
GO:0005198 Function Structural molecule activity IDA 22226963
GO:0005484 Function SNAP receptor activity IBA 21873635
GO:0005515 Function Protein binding IPI 12773094
GO:0005615 Component Extracellular space IDA 22226963
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID P32856
Protein name Syntaxin-2 (Epimorphin)
Protein function Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00804 Syntaxin
29 226
Syntaxin
Domain
PF05739 SNARE
227 279
SNARE domain
Family
Sequence
Sequence length 288
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
KEGG
 
  SNARE interactions in vesicular transport
Synaptic vesicle cycle
 
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Schizophrenia Schizophrenia rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 29064472
Unknown
Disease name Disease term dbSNP ID References
Bipolar disorder Bipolar Disorder 29064472
Schizoaffective disorder Schizoaffective Disorder 29064472

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