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RAB12 (RAB12, member RAS oncogene family)

Gene

201475

RAB12, member RAS oncogene family

RAB12

18p11.22

Show/Hide all(181)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020325	hsa-miR-130b-3p	Sequencing	20371350
MIRT021142	hsa-miR-186-5p	Sequencing	20371350
MIRT025992	hsa-miR-148a-3p	Sequencing	20371350
MIRT031886	hsa-miR-16-5p	Proteomics	18668040
MIRT053406	hsa-miR-629-5p	Microarray	23807165
MIRT025992	hsa-miR-148a-3p	PAR-CLIP	21572407
MIRT080878	hsa-miR-148b-3p	PAR-CLIP	21572407
MIRT080877	hsa-miR-152-3p	PAR-CLIP	21572407
MIRT080876	hsa-miR-143-5p	PAR-CLIP	21572407
MIRT025992	hsa-miR-148a-3p	PAR-CLIP	21572407
MIRT080878	hsa-miR-148b-3p	PAR-CLIP	21572407
MIRT080877	hsa-miR-152-3p	PAR-CLIP	21572407
MIRT080876	hsa-miR-143-5p	PAR-CLIP	21572407
MIRT080851	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT080848	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT080851	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT080847	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT080854	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT080849	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT080858	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT080848	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT025992	hsa-miR-148a-3p	PAR-CLIP	21572407
MIRT080878	hsa-miR-148b-3p	PAR-CLIP	21572407
MIRT080877	hsa-miR-152-3p	PAR-CLIP	21572407
MIRT080876	hsa-miR-143-5p	PAR-CLIP	21572407
MIRT025992	hsa-miR-148a-3p	PAR-CLIP	21572407
MIRT080878	hsa-miR-148b-3p	PAR-CLIP	21572407
MIRT080877	hsa-miR-152-3p	PAR-CLIP	21572407
MIRT080876	hsa-miR-143-5p	PAR-CLIP	21572407
MIRT1281609	hsa-miR-106a	CLIP-seq
MIRT1281610	hsa-miR-106b	CLIP-seq
MIRT1281611	hsa-miR-1197	CLIP-seq
MIRT1281612	hsa-miR-140-3p	CLIP-seq
MIRT1281613	hsa-miR-148a	CLIP-seq
MIRT1281614	hsa-miR-148b	CLIP-seq
MIRT1281615	hsa-miR-152	CLIP-seq
MIRT1281616	hsa-miR-153	CLIP-seq
MIRT1281617	hsa-miR-17	CLIP-seq
MIRT1281618	hsa-miR-186	CLIP-seq
MIRT1281619	hsa-miR-1912	CLIP-seq
MIRT1281620	hsa-miR-20a	CLIP-seq
MIRT1281621	hsa-miR-20b	CLIP-seq
MIRT1281622	hsa-miR-219-5p	CLIP-seq
MIRT1281623	hsa-miR-3117-3p	CLIP-seq
MIRT1281624	hsa-miR-3130-5p	CLIP-seq
MIRT1281625	hsa-miR-3133	CLIP-seq
MIRT1281626	hsa-miR-3140-3p	CLIP-seq
MIRT1281627	hsa-miR-3200-3p	CLIP-seq
MIRT1281628	hsa-miR-329	CLIP-seq
MIRT1281629	hsa-miR-345	CLIP-seq
MIRT1281630	hsa-miR-3591-5p	CLIP-seq
MIRT739006	hsa-miR-3613-3p	CLIP-seq
MIRT1281631	hsa-miR-362-3p	CLIP-seq
MIRT1281632	hsa-miR-3659	CLIP-seq
MIRT1281633	hsa-miR-3662	CLIP-seq
MIRT1281634	hsa-miR-3671	CLIP-seq
MIRT1281635	hsa-miR-3676	CLIP-seq
MIRT1281636	hsa-miR-412	CLIP-seq
MIRT1281637	hsa-miR-4272	CLIP-seq
MIRT1281638	hsa-miR-4280	CLIP-seq
MIRT1281639	hsa-miR-4325	CLIP-seq
MIRT1281640	hsa-miR-4423-3p	CLIP-seq
MIRT1281641	hsa-miR-4445	CLIP-seq
MIRT1281642	hsa-miR-448	CLIP-seq
MIRT1281643	hsa-miR-4482	CLIP-seq
MIRT1281644	hsa-miR-4668-3p	CLIP-seq
MIRT1281645	hsa-miR-4698	CLIP-seq
MIRT1281646	hsa-miR-4699-3p	CLIP-seq
MIRT1281647	hsa-miR-4724-3p	CLIP-seq
MIRT1281648	hsa-miR-4782-3p	CLIP-seq
MIRT1281649	hsa-miR-4797-5p	CLIP-seq
MIRT1281650	hsa-miR-485-3p	CLIP-seq
MIRT1281651	hsa-miR-503	CLIP-seq
MIRT1281652	hsa-miR-507	CLIP-seq
MIRT1281653	hsa-miR-508-3p	CLIP-seq
MIRT1281654	hsa-miR-519d	CLIP-seq
MIRT1281655	hsa-miR-520d-5p	CLIP-seq
MIRT1281656	hsa-miR-520g	CLIP-seq
MIRT1281657	hsa-miR-520h	CLIP-seq
MIRT1281658	hsa-miR-524-5p	CLIP-seq
MIRT1281659	hsa-miR-548m	CLIP-seq
MIRT1281660	hsa-miR-557	CLIP-seq
MIRT1281661	hsa-miR-586	CLIP-seq
MIRT1281662	hsa-miR-607	CLIP-seq
MIRT1281663	hsa-miR-651	CLIP-seq
MIRT1281664	hsa-miR-759	CLIP-seq
MIRT1281665	hsa-miR-890	CLIP-seq
MIRT1281666	hsa-miR-93	CLIP-seq
MIRT1920843	hsa-miR-4719	CLIP-seq
MIRT1920844	hsa-miR-4760-3p	CLIP-seq
MIRT1920845	hsa-miR-513b	CLIP-seq
MIRT1920843	hsa-miR-4719	CLIP-seq
MIRT1920844	hsa-miR-4760-3p	CLIP-seq
MIRT1920845	hsa-miR-513b	CLIP-seq
MIRT1281611	hsa-miR-1197	CLIP-seq
MIRT1281612	hsa-miR-140-3p	CLIP-seq
MIRT1281623	hsa-miR-3117-3p	CLIP-seq
MIRT1281625	hsa-miR-3133	CLIP-seq
MIRT1281628	hsa-miR-329	CLIP-seq
MIRT1281630	hsa-miR-3591-5p	CLIP-seq
MIRT739006	hsa-miR-3613-3p	CLIP-seq
MIRT1281631	hsa-miR-362-3p	CLIP-seq
MIRT1281634	hsa-miR-3671	CLIP-seq
MIRT1281637	hsa-miR-4272	CLIP-seq
MIRT1281638	hsa-miR-4280	CLIP-seq
MIRT2083254	hsa-miR-4282	CLIP-seq
MIRT2083255	hsa-miR-4662a-3p	CLIP-seq
MIRT1920843	hsa-miR-4719	CLIP-seq
MIRT1920844	hsa-miR-4760-3p	CLIP-seq
MIRT1281650	hsa-miR-485-3p	CLIP-seq
MIRT1920845	hsa-miR-513b	CLIP-seq
MIRT2083256	hsa-miR-567	CLIP-seq
MIRT1281662	hsa-miR-607	CLIP-seq
MIRT1281663	hsa-miR-651	CLIP-seq
MIRT2308599	hsa-miR-1279	CLIP-seq
MIRT2308600	hsa-miR-130a	CLIP-seq
MIRT2308601	hsa-miR-130b	CLIP-seq
MIRT2308602	hsa-miR-1323	CLIP-seq
MIRT1281612	hsa-miR-140-3p	CLIP-seq
MIRT2308603	hsa-miR-142-3p	CLIP-seq
MIRT1281616	hsa-miR-153	CLIP-seq
MIRT1281619	hsa-miR-1912	CLIP-seq
MIRT2308604	hsa-miR-199a-5p	CLIP-seq
MIRT2308605	hsa-miR-199b-5p	CLIP-seq
MIRT1281622	hsa-miR-219-5p	CLIP-seq
MIRT2308606	hsa-miR-297	CLIP-seq
MIRT2308607	hsa-miR-298	CLIP-seq
MIRT2308608	hsa-miR-301a	CLIP-seq
MIRT2308609	hsa-miR-301b	CLIP-seq
MIRT1281623	hsa-miR-3117-3p	CLIP-seq
MIRT1281624	hsa-miR-3130-5p	CLIP-seq
MIRT1281625	hsa-miR-3133	CLIP-seq
MIRT1281626	hsa-miR-3140-3p	CLIP-seq
MIRT1281628	hsa-miR-329	CLIP-seq
MIRT1281630	hsa-miR-3591-5p	CLIP-seq
MIRT739006	hsa-miR-3613-3p	CLIP-seq
MIRT1281631	hsa-miR-362-3p	CLIP-seq
MIRT1281633	hsa-miR-3662	CLIP-seq
MIRT2308610	hsa-miR-3666	CLIP-seq
MIRT2308611	hsa-miR-3691-3p	CLIP-seq
MIRT2308612	hsa-miR-3923	CLIP-seq
MIRT1281637	hsa-miR-4272	CLIP-seq
MIRT1281638	hsa-miR-4280	CLIP-seq
MIRT2308613	hsa-miR-4295	CLIP-seq
MIRT2308614	hsa-miR-4305	CLIP-seq
MIRT1281639	hsa-miR-4325	CLIP-seq
MIRT1281641	hsa-miR-4445	CLIP-seq
MIRT2308615	hsa-miR-4464	CLIP-seq
MIRT1281642	hsa-miR-448	CLIP-seq
MIRT1281643	hsa-miR-4482	CLIP-seq
MIRT2308616	hsa-miR-454	CLIP-seq
MIRT2308617	hsa-miR-4671-3p	CLIP-seq
MIRT1281645	hsa-miR-4698	CLIP-seq
MIRT2308618	hsa-miR-4704-5p	CLIP-seq
MIRT2308619	hsa-miR-4748	CLIP-seq
MIRT2308620	hsa-miR-4762-5p	CLIP-seq
MIRT2308621	hsa-miR-4778-5p	CLIP-seq
MIRT1281648	hsa-miR-4782-3p	CLIP-seq
MIRT1281650	hsa-miR-485-3p	CLIP-seq
MIRT1281653	hsa-miR-508-3p	CLIP-seq
MIRT2308622	hsa-miR-548o	CLIP-seq
MIRT2083256	hsa-miR-567	CLIP-seq
MIRT1281662	hsa-miR-607	CLIP-seq
MIRT2308623	hsa-miR-628-3p	CLIP-seq
MIRT2308624	hsa-miR-663b	CLIP-seq
MIRT1281625	hsa-miR-3133	CLIP-seq
MIRT739006	hsa-miR-3613-3p	CLIP-seq
MIRT1281642	hsa-miR-448	CLIP-seq
MIRT1281646	hsa-miR-4699-3p	CLIP-seq
MIRT739006	hsa-miR-3613-3p	CLIP-seq
MIRT1281626	hsa-miR-3140-3p	CLIP-seq
MIRT1281637	hsa-miR-4272	CLIP-seq
MIRT1281625	hsa-miR-3133	CLIP-seq
MIRT739006	hsa-miR-3613-3p	CLIP-seq
MIRT2083254	hsa-miR-4282	CLIP-seq
MIRT1281639	hsa-miR-4325	CLIP-seq
MIRT1281652	hsa-miR-507	CLIP-seq
MIRT1281660	hsa-miR-557	CLIP-seq
MIRT2457585	hsa-miR-590-3p	CLIP-seq
MIRT1281625	hsa-miR-3133	CLIP-seq
MIRT739006	hsa-miR-3613-3p	CLIP-seq

Show/Hide all(26)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0003924	Function	GTPase activity	IEA
GO:0005515	Function	Protein binding	IPI	26824392
GO:0005525	Function	GTP binding	IEA
GO:0005764	Component	Lysosome	ISS
GO:0005765	Component	Lysosomal membrane	IEA
GO:0005768	Component	Endosome	IBA	21873635
GO:0005776	Component	Autophagosome	IEA
GO:0005794	Component	Golgi apparatus	IBA	21873635
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IBA	21873635
GO:0006904	Process	Vesicle docking involved in exocytosis	IBA	21873635
GO:0006914	Process	Autophagy	IEA
GO:0008021	Component	Synaptic vesicle	IBA	21873635
GO:0008333	Process	Endosome to lysosome transport	ISS
GO:0009306	Process	Protein secretion	IBA	21873635
GO:0017157	Process	Regulation of exocytosis	IBA	21873635
GO:0019003	Function	GDP binding	IDA	20937701
GO:0032482	Process	Rab protein signal transduction	IEA
GO:0032593	Component	Insulin-responsive compartment	IBA	21873635
GO:0032869	Process	Cellular response to insulin stimulus	IBA	21873635
GO:0044257	Process	Cellular protein catabolic process	ISS
GO:0055037	Component	Recycling endosome	IBA	21873635
GO:0055038	Component	Recycling endosome membrane	ISS
GO:0055038	Component	Recycling endosome membrane	TAS
GO:0072659	Process	Protein localization to plasma membrane	IBA	21873635

MIM	HGNC	e!Ensembl
616448	31332	ENSG00000206418

Protein

UniProt ID

Q6IQ22

Protein name

Ras-related protein Rab-12 (EC 3.6.5.2)

Protein function

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to r

PDB

2IL1 , 8VH4 , 8VH5

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00071	Ras	44 → 206	Ras family	Domain

Sequence

MDPGAALQRRAGGGGGLGAGSPALSGGQGRRRKQPPRPADFKLQVIIIGSRGVGKTSLME
RFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQERFNSITSAYYRSAKGIIL
VYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLDCETDREITRQQGEKFAQQITGM
RFCEASAKDNFNVDEIFLKLVDDILKKMPLDILRNELSNSILSLQPEPEIPPELPPPRPH
VRCC

Sequence length

244

Interactions

View interactions

	Reactome
			RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs

Associated diseases

Show/Hide Unknown Diseases (1)

Unknown
Disease name	Disease term	dbSNP ID	References
Myocardial ischemia	Myocardial Ischemia		16214533

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