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EMP1 (epithelial membrane protein 1)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
2012
Gene nameGene Name - the full gene name approved by the HGNC.
Epithelial membrane protein 1
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
EMP1
SynonymsGene synonyms aliases
CL-20, EMP-1, TMP
ChromosomeChromosome number
12
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12p13.1
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT005075 hsa-miR-34a-5p Microarray, Northern blot 17540599
MIRT019100 hsa-miR-335-5p Microarray 18185580
MIRT019984 hsa-miR-375 Microarray 20215506
MIRT023169 hsa-miR-124-3p Microarray 18668037
MIRT437637 hsa-miR-152-3p Microarray, qRT-PCR 22815788
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 12107182, 25416956, 32296183
GO:0005886 Component Plasma membrane IBA 21873635
GO:0005886 Component Plasma membrane IDA 12107182
GO:0008219 Process Cell death IDA 12107182
GO:0008544 Process Epidermis development TAS 7499420
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID P54849
Protein name Epithelial membrane protein 1 (EMP-1) (CL-20) (Protein B4B) (Tumor-associated membrane protein)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00822 PMP22_Claudin
1 151
PMP-22/EMP/MP20/Claudin family
Family
Sequence
Sequence length 157
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
KEGG
 
  Focal adhesion  
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Prostate cancer Malignant neoplasm of prostate rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 17199135
Unknown
Disease name Disease term dbSNP ID References
Mental depression Unipolar Depression, Major Depressive Disorder rs587778876, rs587778877 21146590
Miscarriage Miscarriage 18539642
Prostatic neoplasms Prostatic Neoplasms 17199135

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